Download or read book Targeting Oral Cancer written by Andrew Fribley and published by Springer. This book was released on 2016-02-29 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides research-oriented care providers with up-to-date information on the oral cancer patient population, the ways in which we are treating them, and the scientific approaches being pursued in order to improve survival and reduce treatment-related morbidity. The text is organized into three sections covering epidemiology and management, cancer development and biomarkers, and breaking developments and novel approaches for drug discovery. The first section includes discussion of the emerging role of HPV in oral cancer and explains the surgical, chemotherapy and radiation approaches to treatment. Aspects such as molecular progression, the role of cancer stem cells in tumor development, and the value of various biomarkers are then examined. The final section is devoted to the latest advances and covers, among other topics, current clinical trials, emerging drug targets, and targeting of the unfolded protein response and of mediators of coagulation.

Download or read book Textbook of Oral Cancer written by Saman Warnakulasuriya and published by Springer Nature. This book was released on 2020-02-22 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive multidisciplinary book examines all aspects of cancers of the mouth and oropharynx with the aim of equipping advanced students and practitioners in the early stages of specialist training with an up-to-date guide and reference. A multinational team of authors – all experts in the field of oral oncology – provide illuminating contributions on the full range of relevant topics: epidemiology, risk factors, clinical features, staging and prognostic factors, pathology, diagnostic techniques, disease prevention, surgery, radiotherapy, and chemotherapy. Molecular biology, molecular targeted therapies for advanced cases, and future diagnostic and prognostic applications of new technologies also receive careful attention. In providing a wealth of essential information and guidance in a practical format, the book will be a superb asset for senior graduate students in dentistry and specialist trainees in head and neck oncology. It will also be of high value for the many physicians, surgeons, pathologists, dentists, and specialists involved in the prevention, diagnosis, and management of squamous cell carcinomas of the oral cavity and oropharynx.

Download or read book Screening for Oral Cancer written by U. S. Department of Health and Human Services and published by Createspace Independent Publishing Platform. This book was released on 2013-05-28 with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2004, the U.S Preventive Services Task Force (USPSTF) found insufficient evidence in its review to recommend for or against screening for oral cancer. In this review, we are updating the evidence search and analysis to allow this recommendation to be reconsidered. Oral cancer includes cancers of the lip, oral cavity, and pharynx. Ninety percent of cancers of the oral cavity are squamous cell carcinomas (SCCs) arising from the mucosal lining. The other 10 percent of oral cancers are malignant melanomas, salivary gland tumors, sarcomas of the soft tissues or jaw bones, nonHodgkin's lymphomas, or metastases from extra-oral primary tumors. The USPSTF requested this targeted update to focus on the evidence gap in the conceptual framework about screening for oral cancer (i.e., any test or combination of tests used to detect PMDs or cancer of the lip, oral cavity, or pharynx). The two key questions are: Key Question 1 (KQ 1): Does screening for oral cancer reduce morbidity or mortality? Key Question 2 (KQ 2): What are the performance characteristics of the screening oral examination as a means of identifying oral cancer or PMDs for oral cancer?

Download or read book Inflammation and Oral Cancer written by Hiroyuki Tomita and published by Academic Press. This book was released on 2021-09-01 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Inflammation and Oral Cancer: From Bench to Bedside discusses all aspects surrounding the relationship between inflammation and oral cancer, from basic science to the translational research that helps in the optimization of clinical management strategies. The book discusses topics such as chronic inflammation and cancer in oral cavity, the role of HPV in oral inflammation and cancer, rodent models of oral cancer, and epigenetics in oral inflammation and cancer. This is a valuable resource for cancer researchers, oncologists and members of biomedical field who are interested in learning more about the diverse aspects of inflammation and oral cancer. Inflammation in oral mucosa can remodel the topography of the overlying epithelium. If such inflammation is chronic, it can have fundamental clinical consequences, the principal of which can be premalignant lesions throughout the alimentary tract. Furthermore, mucosal inflammation, even if subtle, is the single most common pathway for oral cancer - therefore it is very important to understand these interactions in detail. Presents animal models of oral cancers for use in research Discusses epigenetics in oral cancers, along with risk factors such as tabaco and alcohol Encompasses detailed information on human papilloma virus (HPV) and its risk in oral inflammation and cancer

Download or read book Development of Oral Cancer written by Ala-Eddin Al Moustafa and published by Springer. This book was released on 2017-08-03 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aims to provide the reader with a complete understanding of the development of oral cancer by explaining the role of a wide variety of implicated risk factors and identifying their gene targets and key regulators. Some of the discussed risk factors are well known, including smoking, alcohol, betel quid chewing, and oncoviruses such as high-risk human papillomaviruses and Epstein-Barr virus; however, careful attention is also paid to less widely recognized factors, such as Qat chewing and yerba Mate consumption. The book concludes by describing and evaluating the most important strategies currently available for the prevention of oral carcinogenesis in humans. In presenting the most up-todate research and knowledge on these topics, this book will serve as a valuable source of up-to-date information for oncologists, cancer scientists, and medical students.

Download or read book Oral and Maxillofacial Surgery for the Clinician written by Krishnamurthy Bonanthaya and published by Springer Nature. This book was released on 2021 with total page 1965 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an open access book with CC BY 4.0 license. This comprehensive open access textbook provides a comprehensive coverage of principles and practice of oral and maxillofacial surgery. With a range of topics starting from routine dentoalveolar surgery to advanced and complex surgical procedures, this volume is a meaningful combination of text and illustrations including clinical photos, radiographs, and videos. It provides guidance on evidence-based practices in context to existing protocols, guidelines and recommendations to help readers deal with most clinical scenarios in their daily surgical work. This multidisciplinary textbook is meant for postgraduate trainees, young practicing oral surgeons and experienced clinicians, as well as those preparing for university and board certification exams. It also aids in decision-making, the implementation of treatment plans and the management of complications that may arise. This book is an initiative of Association of Oral and Maxillofacial Surgeons of India (AOMSI) to its commitment to academic medicine. As part of this commitment, this textbook is in open access to help ensure widest possible dissemination to readers across the world. ; Open access Unique presentation with contents divided into color-coded core competency gradations Covers all aspects of oral and maxillofacial surgery Supplemented with videos of all commonly carried out procedures as operative video Every chapter or topic concludes with "future perspective" and addresses cutting edge advances in each area Every topic has a pull out box that provides the most relevant systematic reviews/ key articles to every topic.

Download or read book Histological Typing of Cancer and Precancer of the Oral Mucosa written by J.J. Pindborg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book includes more clinical aspects and concentrates on cancer and precancer of the oral mucosa rather than attempting to cover all benign and malignant tumours of the oral and oropharyngeal tissue. One main emphasis is the significance of the clinical features of the various lesions discussed. Attention is also drawn to those conditions particular to the oral mucosa that may give rise to appearances which are important in differential diagnoses but can be misleading to those who do not have detailed knowledge of the tissue involved. The TNM-classification for malignant tumours of the lip and oral cavity is also included.

Download or read book Targeting in Argininosuccinate Synthetase in Human Oral Cancer written by 黃正池 and published by . This book was released on 2011 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Oral Cancer written by Sol Silverman and published by PMPH-USA. This book was released on 2003 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: new edition of the definitive Oral Cancer, provides a multidisciplinary approach to oral cancer prevention, diagnosis, treatment, and rehabilitation. The effective combination of both authoritative text and colored atlas has produced a thorough examination into this complex disease. Updates include (1) epidemiology, demographics and trends, (2) maxillofacial prosthetics, newer materials and advances in implants, and (3) managing complications in therapy. Expansions in this Fifth Edition comprise (1) new data on viral etiology, genetics and cell markers of oral cancer, and premalignant lesions, (2) diagnosis, staging, imaging, and nutrition, (3) genomics and molecular progression, (4) control of malignant lesions with newer data on agents, mechanisms, and the effectiveness of chemoprevention, and (5) additional illustrations in the MR imaging and PET scans section. New coverage incorporates (1) therapeutic advances in surgery, radiation, and chemotherapy, (2) newer agents, including combinations, radiation, survival morbidity, and quality of life, (3) newer and expanded tobacco data, along with smoking cessation, (4) sections on nutritional biochemistry and modern molecular analysis, and (5) new therapies for salivary gland malignancies.

Download or read book Controversies in Oral Cancer written by K. Alok Pathak and published by Springer. This book was released on 2015-10-30 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume brings together the work of experts from clinical and basic sciences specialties and addresses some of the controversial issues and advances in the management of oral cancer. Improving the outcome for the oral cancer patient will require dedicated work from many disciplines working together as multidisciplinary units. The book is meant for medical students, residents and consultants in various disciplines, including otolaryngology, head and neck surgery, neurosurgery, plastic surgery, maxillofacial surgery and oncology.

Download or read book Screening for Oral Cancer written by and published by . This book was released on with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Betel quid and Areca nut Chewing and Some Areca nut derived Nitrosamines written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by IARC. This book was released on 2004 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: A working group of sixteen experts from seven countries re-evaluated the evidence of the carcinogenicity of betel-quid and areca-nut chewing and some areca-nut related nitrosamines. Betel-quid and areca-nut chewing are widely practised in many parts of Asia and in Asian-migrant communities elsewhere in the world. There are hundreds of millions of users worldwide. They evaluated betel quid with tobacco as carcinogenic to humans (Group 1) on the basis of sufficient evidence of an increased risk of cancer of the oral cavity, pharynx and oesophagus. The working group reviewed epidemiological studies of human cancer, mainly studies from India, Pakistan and Taiwan (China). Studies on betel quid with tobacco and areca nut with tobacco in experimental animals now also provide sufficient evidence of carcinogenicity. The working group also evaluated betel quid without tobacco as carcinogenic to humans (Group 1), on the basis of sufficient evidence of an increased risk of oral cancer. Studies on betel quid without tobacco and areca nut without tobacco in experimental animals now also provide sufficient evidence of carcinogenicity. Areca nut, a common ingredient of betel quid and many different chewing preparations, including those available commercially, has been observed to cause oral submucous fibrosis

Download or read book Oral Cancer Detection written by Prashanth Panta and published by Springer. This book was released on 2019-01-04 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph equips clinicians with the knowledge required to detect oral cancer at the earliest possible stage while simultaneously inspiring researchers to work on novel methods of detection. All the methods employed in the oral cancer context are considered, from simple ones like oral screening to more complex emerging optical methods and biomarker identification strategies. Individual chapters focus on conventional oral screening and application of vital stains, optical methods like white light based fluorescence-reflectance imaging, narrow band imaging, direct-oral-microscopy, and more advanced methods like optical coherence tomography, an in-vivo optical biopsy technique, and photo-acoustic imaging that allows visualization of deeper tissue changes. Novel electrical methods like bio-impedance assessment, occult biophysical methods like crystallization test, and the most promising salivary biomarkers and point-of-care opportunities are covered. Helpful information is also provided on essential topics including, oral potentially malignant disorders, biological aspects and molecular mechanisms underlying oral cancer progression, global epidemiology, concept of diagnostic delays, traditional imaging, and classic histopathology and microscopic features. The newer techniques are currently of active research interest, and can soon become powerful chair-side tools with potential to reduce diagnostic delays and improve survival.

Download or read book Oral Cancer written by Gokul Sridharan and published by BoD – Books on Demand. This book was released on 2022-01-07 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oral cancer is a common disease with a high incidence of morbidity and mortality. Despite technological advancements in diagnosis and treatment, the five-year survival rate is low. Researchers worldwide are attempting to identify new and novel methods for early diagnosis and better treatment of oral cancer to improve survival rate and quality of life post recovery. This book examines current concepts in oral cancer and emphasizes future perspectives for diagnosis and treatment of disease for better clinical outcomes and patient care.

Download or read book Advances in the Multidisciplinary Management of Oral Cancer written by Alberto Paderno and published by Frontiers Media SA. This book was released on 2022-02-02 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Biology of Oral Cancer written by Prakash S. Bisen and published by CRC Press. This book was released on 2013-07-15 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite a decline in developed countries, cancer has consistently maintained its status as one of the top killers since time immemorial. Exploring cancer management and treatment at the molecular level, Biology of Oral Cancer: Key Apoptotic Regulators presents a key molecular event-apoptosis-in relation to genesis and progression of oral cancer. Th

Download or read book The Translational and Therapeutic Potential of the Tumor Microenvironment in Oral Cancer 2nd edition written by Keith David Hunter and published by Frontiers Media SA. This book was released on 2022-11-06 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the importance of the tissue surrounding a tumour, commonly termed the tumour microenvironment (TME), has been increasingly recognized. Whilst likely to play a tumour-suppressive role in the early stages of carcinogenesis, a wide array of evidence indicates the TME becomes corrupted by the presence of malignant cells and becomes tumour permissive, promoting growth, metastasis, immune evasion and therapeutic resistance. The major components of the TME are fibroblasts, immune cells, endothelial cells and the extracellular matrix in which they are embedded, but this is highly heterogeneous and site-specific, with other cells such as adipose, bone and neuronal likely to play a prominent role in some tumours. Other patient-specific factors are also likely to be important, including age and previous treatment. The multi-faceted contribution of the TME to tumourigenesis offers great potential for therapeutic intervention and biomarker development, but its inherent heterogeneity necessitates in-depth understanding of the contribution of different components of the TME to tumourigenesis to underpin clinical translation. This Research Topic will encompass a wide range of areas relating to the therapeutic opportunities offered by the tumour microenvironment of oral cancer, including (but not limited to) the role of fibroblasts, infiltrating immune and inflammatory cells and the extracellular matrix, including the influence of aging and previous treatment. The collection can encompass a range of oral tumours including mucosal cancers, salivary gland cancers and tumours of the jaws, including odontogenic tumours. This Research Topic will have a translational focus to it and may include biomarker development. We are particularly interested in receiving papers describing: - fundamental mechanisms underlying the contribution of components of the tumour microenvironment to carcinogenesis, tumour growth, metastasis and extra-nodal extension - the contribution of the physico-chemical environment to tumour progression - intercellular signalling pathways within the tumour microenvironment - the impact of ageing and previous treatment on the tumour microenvironment - tumour microenvironmental biomarkers - therapeutic targeting of components of the tumour microenvironment We welcome primary articles, review articles and mini reviews.