Download or read book Systems Pharmacology and Traditional Chinese Medicine written by Aiping Lu and published by Frontiers Media SA. This book was released on 2021-06-23 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Network Pharmacology and Traditional Medicine written by Shao Li and published by Frontiers Media SA. This book was released on 2020-10-08 with total page 438 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Download or read book Network Pharmacology written by Shao Li and published by Springer Nature. This book was released on 2021-09-29 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.
Download or read book Computational Systems Pharmacology and Toxicology written by Rudy J Richardson and published by Royal Society of Chemistry. This book was released on 2017-03-03 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: The network approaches of systems pharmacology and toxicology serve as early predictors of the most relevant screening approach to pursue both in drug discovery and development and ecotoxicological assessments. Computational approaches have the potential to improve toxicological experimental design, enable more rapid drug efficacy and safety testing and also reduce the number of animals used in experimentation. Rapid advances in availability of computing technology hold tremendous promise for advancing applied and basic science and increasing the efficiency of risk assessment. This book provides an understanding of the basic principles of computational toxicology and the current methods of predictive toxicology using chemical structures, toxicity-related databases, in silico chemical-protein docking, and biological pathway tools. The book begins with an introduction to systems pharmacology and toxicology and computational tools followed by a section exploring modelling adverse outcomes and events. The second part of the book covers the discovery of protein targets and the characterisation of toxicant-protein interactions. Final chapters include case studies and additionally discuss interactions between phytochemicals and Western therapeutics. This book will be useful for scientists involved in environmental research and risk assessment. It will be a valuable resource for postgraduate students and researchers wishing to learn about key methods used in studying biological targets both from a toxicity and pharmacological activity standpoint.
Download or read book Drug Discovery and Traditional Chinese Medicine written by Yuan Lin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: The "First International Conference on Traditional Chinese Medicine: Science, Regulation and Globalization" was held from August 30 to September 2, 2000 at the University of Maryland at College Park, Maryland. There were approximately 250 participants from the Peoples Republic of China, Taiwan, Hong Kong and the United States. This objective of this conference was to promote international collaboration for the modernization of Traditional Chinese herbal medicines (TCM) and their introduction into the global health care system. It was mainly sponsored by the Ministry of Science and Technology of the People's Republic of China and the NllI National Center for Complementary and Alternative Medicine (NCCAM). It was organized by Dr. William Tai, then director of the Institute of Global Chinese Affairs at the University of Maryland and Dr. Yuan Lin, president of Marco Polo Technologies, Bethesda, MD. This conference was conceived by Dr. Tai two years earlier recognizing that this was an appropriate time and also the unique location of the University of Maryland. Today, there is a growing recognition of the of alternative medicine in modem societies and the rapid loss of importance knowledge about traditional methods for the treatment of the multitude of human illnesses found throughout the world. TCM has been in common use in China for thousands of years; and many of its formulations are well defined.
Download or read book Drug Discovery and Evaluation Methods in Clinical Pharmacology written by H.Gerhard Vogel and published by Springer Science & Business Media. This book was released on 2010-12-15 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these processes can be divided up stepwise we have designed a book series "Drug Discovery and Evaluation" in the form of a recommendation document. The methods to detect drug targets are described in the first volume of this series "Pharmacological Assays" comprising classical methods as well as new technologies. Before going to man, the most suitable compound has to be selected by pharmacokinetic studies and experiments in toxicology. These preclinical methods are described in the second volume „Safety and Pharmacokinetic Assays". Only then are first studies in human beings allowed. Special rules are established for Phase I studies. Clinical pharmacokinetics are performed in parallel with human studies on tolerability and therapeutic effects. Special studies according to various populations and different therapeutic indications are necessary. These items are covered in the third volume: „Methods in Clinical Pharmacology".
Download or read book Network Pharmacology written by Shao Li and published by Springer. This book was released on 2021-09-30 with total page 468 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.
Download or read book Handbook Of Traditional Chinese Medicine In 3 Volumes written by Stevenson Xutian and published by World Scientific. This book was released on 2014-09-19 with total page 1491 pages. Available in PDF, EPUB and Kindle. Book excerpt: For over two thousand years, Traditional Chinese Medicine (TCM) has made many significant contributions to China's growth and prosperity. This textbook, based on the unique characteristics of TCM, discusses its principle theories and presents a comprehensive daily practice guide for health maintenance and disease treatment. The book provides clinical practitioners with a fundamental understanding of the essence of TCM.We highly recommend this book for students interested in TCM, Chinese medicine doctors and other healthcare professionals, biomedical researchers, and interested individuals. Readers will benefit from the inspirational viewpoints discussed in the book.
Download or read book Systems Biology and Its Application in TCM Formulas Research written by Weidong Zhang and published by Academic Press. This book was released on 2018-02-16 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Biology and Its Application in TCM Formulas Research presents a theoretical research system formed for Traditional Chinese Medicine (TCM) formulas, along with information on the study of Shexiang Baoxin Pill (SBP), a TCM formula that has shown significant clinical efficacy in the treatment of cardiovascular diseases. The content combines theory and practice, and includes guidance for both theoretical concepts and operable technical routes. This is a valuable source not only for biomedical researchers involved in Systems Biology studies, but also for students and scientists interested in learning more about Traditional Chinese Medicine and its applications in contemporary medicine. Explains, in detail, the Shexiang Baoxin Pill (SBP), a TCM formula efficiently applied in the treatment of cardiovascular diseases Presents TCM formulas from perspectives of systems biology, basic chemical material groups, modern pharmacology and network biology Offers an overview on biology, modern chemistry and information technology as applied in Systems Biology research
Download or read book What Is Medicine written by Paul U. Unschuld and published by Univ of California Press. This book was released on 2009-09-08 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt: What Is Medicine? Western and Eastern Approaches to Healing is the first comparative history of two millennia of Western and Chinese medicine from their beginnings in the centuries BCE through present advances in sciences like molecular biology and in Western adaptations of traditional Chinese medicine. In his revolutionary interpretation of the basic forces that undergird shifts in medical theory, Paul U. Unschuld relates the history of medicine in both Europe and China to changes in politics, economics, and other contextual factors. Drawing on his own extended research of Chinese primary sources as well as his and others' scholarship in European medical history, Unschuld argues against any claims of "truth" in former and current, Eastern and Western models of physiology and pathology. What Is Medicine? makes an eloquent and timely contribution to discussions on health care policies while illuminating the nature of cognitive dynamics in medicine, and it stimulates fresh debate on the essence and interpretation of reality in medicine's attempts to manage the human organism.
Download or read book Serum Pharmacochemistry of Traditional Chinese Medicine written by Xijun Wang and published by Academic Press. This book was released on 2016-12-27 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: Serum Pharmacochemistry of Traditional Chinese Medicine: Technologies, Strategies and Applications provides a valuable and indispensable guide on the latest methods, research advances, and applications in this area. Chapters offer cutting-edge information on pharmacokinetics and pharmacodynamics, analytical chemistry, traditional medicine, natural products, bioinformatics, new technologies, therapeutic applications, and more. For researchers and students in academia and industry, this book provides a hands-on description of experimental techniques, along with beneficial guidelines to help advance research in the fields of Traditional Chinese Medicine and drug development. Provides a valuable guide for practitioners of serum pharmacochemistry of Traditional Chinese Medicine, along with insights to its current use and future applications Edited and written by leading scientists at the forefront of this research Presents well written chapters that include an introduction, description of the method, and identification of chemical constituents, with applications and references to the latest research and literature
Download or read book Evidence and Rational Based Research on Chinese Drugs written by Hildebert Wagner and published by Springer Science & Business Media. This book was released on 2013-02-11 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: After the successful introduction of acupuncture to the West, recent advances in analytical methods in chemistry, molecular biology and systems biology – especially the development of the “omic” technologies – have again brought Chinese drugs into the focus of research on Traditional Chinese Medicine (TCM). With more than 1000 publications on the chemistry, molecular biology and pharmacology of TCM drugs in international journals over the last 10 years, Chinese drugs are gaining increasingly reputation and impact. These data offer great opportunities for the development of new pharmaceuticals for various clinical applications. International scientists have compiled relevant and trend setting research results in this book. Topics range from the latest methods of quality and safety assurance by chemical and genetic fingerprints to the development of new pharmaceuticals for a future evidence-based therapy e.g. for cancer, cardiovascular, inflammatory or infectious diseases as well as to recent experimental results on multitarget and synergy research for the preparation of multi-extract-pharmaceuticals from TCM.
Download or read book Brain Drug Targeting written by William M. Pardridge and published by Cambridge University Press. This book was released on 2001-05-31 with total page 377 pages. Available in PDF, EPUB and Kindle. Book excerpt: This challenging 2001 book reviews modern neurotherapeutics from the point of view of drug targeting.
Download or read book Chinese Drugs of Plant Origin written by Weici Tang and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 1005 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditional Chinese medicine has been used for thousands of years by a large population. It is currently still serving many of the health needs of the Chinese people; and still enjoying their confi dence it is practised in China in parallel with modern Western medical treatment. In addition to scientific organisations dedi cated to modern Western medicine, e. g. the Chinese Academy of Medical Sciences and various medical schools, a series of parallel institutions have been established in China to promote traditional Chinese medicine, such as the Academy of Traditional Chinese Medicine and training institutions. Almost all hospitals in China have a department of traditional medicine. Furthermore, a large number of scientific journals are dedicated to traditional Chinese medicine, covering both experimental and clinical investigations. Medicinal materials constitute a key topic in the treatment of disease according to traditional Chinese medicine. The Chinese Pharmacopoeia (1985 edition) is therefore divided into two sepa rate volumes, Volume I containing traditional Chinese medicinal materials and preparations and Volume II containing pharmaceu tics of Western medicine. The oldest Chinese review of medicinal materials, Shennong Bencao Jing (100-200 A. D. ), covered 365 herbal drugs. The clas sic compilation in this field, Bencao Gangmu (Compendium of Materia Medica), was published in 1578 by Li Shi-zhen and recorded as many as 1898 crude drugs of plant, animal and min eral origin.
Download or read book The Pharmacology of Chinese Herbs Second Edition written by Kee C. Huang and published by CRC Press. This book was released on 1998-07-27 with total page 538 pages. Available in PDF, EPUB and Kindle. Book excerpt: Records cataloging the healing powers of natural substances - plants, minerals, and animal byproducts - date back more than 4,000 years. There is no denying the effectiveness of traditional Chinese medicine, yet - until recently - the roots of this knowledge were largely lost in superstition and folklore. However, the use of herbs as an alternative medical treatment for many illnesses has increased steadily over the last decade, particularly since such herbs are categorized as "Natural Food Products" and are not yet subject to strict control by the FDA. Reports published in 1996 indicate that more than 10% of the US population has used herbal remedies. This book does not debate the value of Eastern or Western medicine but brings together Chinese herbal lore and Western scientific methods in a current, comprehensive treatise on the pharmacology of Chinese herbs. This second edition of The Pharmacology of Chinese Herbs presents the chemical composition, pharmacological action, toxicity, and therapeutic value of 473 herbs. The book: Classifies herbs according to their therapeutic value Informs how active ingredients in herbs may adversely interact with other herbs or drugs Evaluates which herbs have the potential for more investigation and possible use as drugs Describes the pharmacological action of each herb based on recent scientific study and describes each herb according to Chinese pharmacopoeia and folk medicine Provides a review of Chinese medical history Presents information on how to use modern chemical techniques for enhancing or modifying herbal ingredients into better agents with more strength and activity What's New in the Second Edition Discussions on: Herbs and their specific effects on the immune system Herbs and fertility/infertility Anti-cancer herbs Anti-HIV herbs Anti-malarial herbs Ginseng and ginsenosides Anti-Alzheimer herbs Herbs affecting the nervous system
Download or read book Medical Empathy Pharmacological Systems and Treatment Strategies in Integrative Cardiovascular Chinese Medicine written by Anika Niambi Al-Shura and published by Academic Press. This book was released on 2019-10-18 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical Empathy, Pharmacological Systems, and Treatment Strategies in Integrative Cardiovascular Chinese Medicine, volume two in the Integrative Cardiovascular Chinese Medicine series, presents sections on holism and humanity in medicine, considering the patient, medical empathy in prescribing, modifying and weaning, an overview of pharmacologic systems, an overview of pharmacology sciences and the cardiovascular drug classes and types as revealed from perspectives of Chinese and Western medicine, including descriptions of pharmaceutical drugs from China and the United States, with current pictures and inpatient directions. Finally, principles and treatments according to disease stages for each cardiovascular disease within the scope of integrative medicine is outlined. This important reference will aid cardiovascular researchers in the study of integrative Chinese and Western medicine and provide a clear, structured base to guide clinical practice and encourage collaboration between Chinese and Western medicine practitioners Integrates Western and Chinese Medicine for a realistic and complete scope of cardiology treatment, establishing the basis for standardization and rationale of inclusion of Traditional Chinese Medicine in cardiology Identifies and inspires ideas where future research can develop and strengthen Contains a breakdown comparison of herb and drug formula constituents on the pharmacokinetic and dynamic level Includes personalized medicine explaining the human genetics associated with the use of medicines and the advantages/disadvantages of herbs and/or drugs within treatment
Download or read book Modern Computational Approaches to Traditional Chinese Medicine written by Zhaohui Wu and published by Elsevier. This book was released on 2012-07-16 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognized as an essential component of Chinese culture, Traditional Chinese Medicine (TCM) is both an ancient medical system and one still used widely in China today. TCM's independently evolved knowledge system is expressed mainly in the Chinese language and the information is frequently only available through ancient classics and confidential family records, making it difficult to utilize. The major concern in TCM is how to consolidate and integrate the data, enabling efficient retrieval and discovery of novel knowledge from the dispersed data. Computational approaches such as data mining, semantic reasoning and computational intelligence have emerged as innovative approaches for the reservation and utilization of this knowledge system. Typically, this requires an inter-disciplinary approach involving Chinese culture, computer science, modern healthcare and life sciences. This book examines the computerization of TCM information and knowledge to provide intelligent resources and supporting evidences for clinical decision-making, drug discovery, and education. Recent research results from the Traditional Chinese Medicine Informatics Group of Zhejiang University are presented, gathering in one resource systematic approaches for massive data processing in TCM. These include the utilization of modern Semantic Web and data mining methods for more advanced data integration, data analysis and integrative knowledge discovery. This book will appeal to medical professionals, life sciences students, computer scientists, and those interested in integrative, complementary, and alternative medicine. Interdisciplinary book bringing together Traditional Chinese Medicine and computer scientists Introduces novel network technologies to Traditional Chinese Medicine informatics Provides theory and practical examples and case studies of new techniques
