Download or read book Synthetic Procedures in Nucleic Acid Chemistry Preparation of purines pyrimidines nucleosides and nucleotides written by W. Werner Zorbach and published by . This book was released on 1968 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Preparation of Purines Pyrimidines Nucleosides and Nucleotides written by and published by . This book was released on 1968 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Band 1.
Download or read book Synthetic Procedures in Nucleic Acid Chemistry Volume 1 Preparation of Purines Pyrimidines Nucleosides and Nucleotides written by W. Werner Zorbach and published by . This book was released on 1968 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Preparation of Purines Pyrimidines Nucleosides and Nucleotides written by William Werner Zorbach and published by . This book was released on 1973 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Purines Pyrimidines and Nucleotides and the Chemistry of Nucleic Acids written by Tilo Lajos Vittorio Ulbricht and published by . This book was released on 1964 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Synthetic Procedures in Nucleic Acid Chemistry Physical and physicochemical aids in characterization and in determination of structure written by W. Werner Zorbach and published by . This book was released on 1968 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Preperation of Purines Pyrimidines Nucleosides and Nucleotides written by William Werner Zorbach and published by . This book was released on 1968 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives written by Jesús Fernández Lucas and published by John Wiley & Sons. This book was released on 2019-04-29 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review of innovative tools for creative nucleic acid chemists that open the door to novel probes and therapeutic agents Nucleic acids continue to gain importance as novel diagnostic and therapeutic agents. With contributions from noted scientists and scholars, Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives is a practical reference that includes a wide range of approaches for the synthesis of designer nucleic acids and their derivatives. The book covers enzymatic (including chemo-enzymatic) methods, with a focus on the synthesis and incorporation of modified nucleosides. The authors also offer a review of innovative approaches for the non-enzymatic chemical synthesis of nucleic acids and their analogs and derivatives, highlighting especially challenging species. The book offers a concise review of the methods that prepare novel and heavily modified polynucleotides in sufficient amount and purity for most clinical and research applications. This important book: -Presents a timely and topical guide to the synthesis of designer nucleic acids and their derivatives -Addresses the growing market for nucleotide-derived pharmaceuticals used as anti-infectives and chemotherapeutic agents, as well as fungicides and other agrochemicals. -Covers novel methods and the most recent trends in the field -Contains contributions from an international panel of noted scientistics Written for biochemists, medicinal chemists, natural products chemists, organic chemists, and biotechnologists, Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives is a practice-oriented guide that reviews innovative methods for the enzymatic as well as non-enzymatic synthesis of nucleic acid species.
Download or read book Synthetic Procedures in Nucleic Acid Chemistry written by R. Stuart Tipson (jt. auth) and published by . This book was released on 1968 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Purines Pyrimidines and Nucleotides and the Chemistry of Nucleic Acids written by Tilo Lajos Vittorio Ulbricht and published by . This book was released on 1964 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Chemical Synthesis of Nucleoside Analogues written by Pedro Merino and published by John Wiley & Sons. This book was released on 2013-02-12 with total page 859 pages. Available in PDF, EPUB and Kindle. Book excerpt: Compiles current tested and proven approaches to synthesize novel nucleoside analogues Featuring contributions from leading synthetic chemists from around the world, this book brings together and describes tested and proven approaches for the chemical synthesis of common families of nucleoside analogues. Readers will learn to create new nucleoside analogues with desired therapeutic properties by using a variety of methods to chemically modify natural nucleosides, including: Changes to the heterocyclic base Modification of substituents at the sugar ring Replacement of the furanose ring by a different carbo- or heterocyclic ring Introduction of conformational restrictions Synthesis of enantiomers Preparation of hydrolitically stable C-nucleosides Chemical Synthesis of Nucleoside Analogues covers all the major classes of nucleosides, including pronucleotides, C-nucleosides, carbanucleosides, and PNA monomers which have shown great promise as starting points for the synthesis of nucleoside analogues. The book also includes experimental procedures for key reactions related to the synthesis of nucleoside analogues, providing a valuable tool for the preparation of a number of different compounds. Throughout the book, chemical schemes and figures help readers better understand the chemical structures of nucleoside analogues and the methods used to synthesize them. Extensive references serve as a gateway to the growing body of original research studies and reviews in the field. Synthetically modified nucleosides have proven their value as therapeutic drugs, in particular as antiviral and antitumor agents. However, many of these nucleoside analogues have undesirable side effects. With Chemical Synthesis of Nucleoside Analogues as their guide, researchers have a new tool for synthesizing a new generation of nucleoside analogues that can be used as therapeutic drugs with fewer unwanted side effects.
Download or read book Nucleic Acids in Chemistry and Biology written by G Michael Blackburn and published by Royal Society of Chemistry. This book was released on 2015-11-09 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: The structure, function and reactions of nucleic acids are central to molecular biology and are crucial for the understanding of complex biological processes involved. Revised and updated Nucleic Acids in Chemistry and Biology 3rd Edition discusses in detail, both the chemistry and biology of nucleic acids and brings RNA into parity with DNA. Written by leading experts, with extensive teaching experience, this new edition provides some updated and expanded coverage of nucleic acid chemistry, reactions and interactions with proteins and drugs. A brief history of the discovery of nucleic acids is followed by a molecularly based introduction to the structure and biological roles of DNA and RNA. Key chapters are devoted to the chemical synthesis of nucleosides and nucleotides, oligonucleotides and their analogues and to analytical techniques applied to nucleic acids. The text is supported by an extensive list of references, making it a definitive reference source. This authoritative book presents topics in an integrated manner and readable style. It is ideal for graduate and undergraduates students of chemistry and biochemistry, as well as new researchers to the field.
Download or read book The Biochemistry of Plants written by and published by Academic Press. This book was released on 2012-12-02 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Biochemistry of Plants, Volume 14: Carbohydrates provides information pertinent to the fundamental aspects of plant biochemistry. This book deals with the function and structure of the plant cell wall by describing the physical and chemical properties of cell wall components. Organized into 11 chapters, this volume begins with an overview of hexose phosphate metabolism in nonphotosynthetic tissues. This text then examines the findings in fructan structures, conformations, and linkages, the enzymes involved in fructan synthesis and degradation, and their cellular regulation, location, and metabolic role in plants. Other chapters consider the methods employing enzymes to determine starch structure. This book discusses as well the different biosynthetic modes of plant cell walls. The final chapter deals with the various environmental factors that influence expression of the ?-amylase gene, suggesting how molecular biology may help in understanding carbohydrate biochemistry and the enzymes involved in carbohydrate synthesis and metabolism. This book is a valuable resource for plant biochemists.
Download or read book Modified Nucleic Acids written by Kazuhiko Nakatani and published by Springer. This book was released on 2016-04-04 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases. Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs. This unique book addresses new developments and is designed for graduate level and professional research purposes.
Download or read book Nucleoside Triphosphates and their Analogs written by Morteza Vaghefi and published by CRC Press. This book was released on 2016-04-19 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: While adenosine triphosphate (ATP) is described as the universal currency of energy in all living organisms at the cellular level, the actual power lies in its phosphate tail. This book is the first dedicated to the field of nucleoside triphosphate (NTP). Its 13 chapters encompass the contributions of twenty scientists from both academia and industry. It provides collective information on the chemical, physiochemical, and biological properties of both natural and modified NTP and their application in life sciences. Three chapters review families of enzymes that depend on nucleotides for assembling DNA and RNA molecules. The appendix includes supporting NMR data.
Download or read book Prebiotic Chemistry and Chemical Evolution of Nucleic Acids written by César Menor-Salván and published by Springer. This book was released on 2018-08-01 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: The origin of life is one of the biggest unsolved scientific questions. This book deals with the formation and first steps of the chemical evolution of nucleic acids, including the chemical roots behind the origin of their components from the simplest sources in a geochemical context. Chemical evolution encompasses the chemical processes and interactions conducive to self-assembly and supramolecular organization, leading to an increase of complexity and the emergence of life. The book starts with a personal account of the pioneering work of Stanley Miller and Jeffrey Bada on the Chemistry of Origins of Life and how the development of organic chemistry beginning in the 19th century led to the emergence of the field of prebiotic chemistry, situated at the frontier between organic, geo- and biochemistry. It then continues reviewing in tutorial manner current central topics regarding the organization of nucleic acids: the origin of nucleobases and nucleosides, their phosphorylation and polymerization and ultimately, their self-assembly and supramolecular organization at the inception of life.
Download or read book Medical Biochemistry The Big Picture written by Lee W. Janson and published by McGraw Hill Professional. This book was released on 2012-03-25 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get the BIG PICTURE of Medical Biochemistry – and target what you really need to know to ace the course exams and the USMLE Step 1 300 FULL-COLOR ILLUSTRATIONS Medical Biochemistry: The Big Picture is a unique biochemistry review that focuses on the medically applicable concepts and techniques that form the underpinnings of the diagnosis, prognosis, and treatment of medical conditions. Those preparing for the USMLE, residents, as well as clinicians who desire a better understanding of the biochemistry behind a particular pathology will find this book to be an essential reference. Featuring succinct, to-the-point text, more than 300 full-color illustrations, and a variety of learning aids, Medical Biochemistry: The Big Picture is designed to make complex concepts understandable in the shortest amount of time possible. This full-color combination text and atlas features: Progressive chapters that allow you to build upon what you’ve learned in a logical, effective manner Chapter Overviews that orient you to the important concepts covered in that chapter Numerous tables and illustrations that clarify and encapsulate the text Sidebars covering a particular disease or treatment add clinical relevance to topic discussed Essay-type review questions at the end of each chapter allow you to assess your comprehension of the major topics USMLE-style review questions at the end of each section Three appendices, including examples of biochemically based diseases, a review of basic biochemical techniques, and a review of organic chemistry/biochemistry
