Download or read book Synthesis Structure Photophysics and Biological Activity of Platinum II Complexes written by Dileep Atchyuth Kumar Vezzu and published by . This book was released on 2013 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: The synthesis, structure, and photophysical properties of luminescent platinum (II) complexes with different coordination patterns, (C^C*N^N), (N^C*N), (N^N*C) and (N^N^C) are reported, where "C^N or N^N" denotes a bidentate coordination to the platinum to form a five-membered metallacycle and "C*N" denotes a bidentate coordination to the platinum to form a six-membered metallacycle. Sixteen cyclometalated platinum complexes have been synthesized with different coordination patterns, which include six complexes with tridentate N^C*N cyclometalating ligands (13, 14, 15, 16, 17, and 18), five complexes with N^N*C cyclometalating ligands (19a, 19b, 20a, 20b, and 24), three complexes with N^N^C cyclometalating ligands (21a, 21b, and 29) and two complexes with tetradentate C^C*N^N cyclometalating ligands (33 and 34). The structures of the platinum complexes 13, 15, 16, 18, 19a, 19b, 20a, 21a, 21b, 24, 29, 33, and 39 were determined by single crystal X-ray diffraction. In platinum complexes with five-six membered metallacycle (15, 16, 18, 19a, 19b, 20a, 24, and 39), the square geometry of the complexes is improved when compared to that of platinum complexes with five-five membered metallacycle as the biting angle is increased. The tetradentate coordination (C^C*N^N), square planar geometry of complex 33 are revealed from its X-ray crystal structure. The DFT calculations have been carried out on complexes 13, 14, 15, 16, 17, 18, 33, and 34 to examine the molecular orbital character of the complexes, which are used in interpreting the electronic spectra of the complexes. The photophysical properties of the platinum complexes were studied and a majority of the complexes were highly emissive in solution at room temperature. Complex 13 exhibited the highest quantum yield (65%) among all of the complexes. Self quenching was not observed in a majority of the platinum complexes at lower concentrations. The cytotoxicity (IC50) of the complexes in three lung cancerous cell lines and one prostate cancer cell line were determined by MTT assay. The toxic platinum complexes induced the cell death by triggering apoptosis. The interactions of the platinum complexes with plasmid and calf thymus DNA were studied. Activation of caspase -7, PARP, and p53 were also observed in RV1 and HCC827 cell lines when treated with platinum complexes. Complexes 35, 37 and 38 were more potent than the clinically approved drug, cis-platin.
Download or read book THE SYNTHESIS STRUCTURE AND PHOTOPHYSICAL PROPERTIES OF PHOSPHORESCENT CYCLOMETALATED N N C COORDINATED PLATINUM COMPLEXES written by Robert Mroz and published by . This book was released on 2016 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phosphorescent materials based on cyclometalated platinum complexes have attracted a great deal of attention because of their potential in chemical, biological and optoelectronic applications, specifically as emitters in organic light-emitting diode devices. In addition, development of phosphorescent materials emitting in the deep red and/or near infrared region have become a popular area of focus because of their capabilities as chemosensors, in solar cells and bioimaging dyes. Several classes of phosphorescent cyclometalated platinum complexes based on tridentate and tetradentate ligands have already been developed by our lab. In this study, two series of cyclometalated N^N^C Pt(II) complexes 1a-6a and 1b-6b, were designed to emit throughout a wide range of the visible spectrum and were successfully synthesized bearing either a phenyl acetylide or phenyl ancillary ligand. The photophysical properties of complexes can be tuned as desired through methodical modifications of the cyclometalating or ancillary ligand with varying electron accepting or donating moieties. Photophysical studies were conducted on the synthesized complexes and found emission wavelengths ranging from 496-643 nm, quantum yield ([Phi]p) values between 43.0% and [less than] 0.1% and lifetimes ([tau]) as long as 13.1 [micro]s at 298 K. TD-DFT calculations of ground state HOMO and LUMO orbitals, as well as X-ray crystallographic analysis of select complexes were conducted and analyzed. The data comparison of the obtained results between the phenyl acetylide and phenyl coordinated complexes assists in identifying any structure-photophysical property relationships present, which will be discussed in detail.
Download or read book Synthesis and Photophysical Characterization of Tridentate C N N Platinum II Complexes written by Deepak Ravindranathan and published by . This book was released on 2012 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: The synthesis, structure, and photophysical properties of a series of novel, highly luminescent tridentate platinum complexes with general coordination geometry of (C^N*N)-PtL are reported, where "C^N" denotes a coordination of C and N to the platinum to form a five-membered metallacycle and "N*N" denotes a coordination of two N atoms to the platinum to form a six-membered metallacycle; L is a mono anionic ligand such as halides or acetylides. Compared to the known (C^N^N)-PtL type of complexes that were reported to emit with low quantum yields, the structural modification leads to dramatic improvements in phosphorescence efficiency. For example, new complexes (C^N*N)-PtL with L = hexylacetylide and phenylacetylide emitted intensely with quantum yields of 47% and 56%, respectively, latter of which is among the highest quantum yields reported so far for cyclometalated platinum (II) complexes. Selectivity in C-H bond activation by platinum and the exact mechanism of cycloplatination are issues that still remain unclear. A series of ligands which include sp2/sp3, primary/secondary sp3 C-H bonds, and aromatic/vinylic sp2 C-H bonds with a carbon linker between the bipyridine and the carbon groups have been prepared. All ligands have been attempted for cycloplatination in glacial acetic acid and acetonitrile. All ligands produced the same sp2 C-H bond activated complex in both solvents, which suggests that the linker atom does play a role on selectivity.
Download or read book Synthesis and Photophysics of Platinum II Terpyridyl Complexes written by Zhiqiang JI and published by . This book was released on 2009 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Synthesis and Photophysics of Platinum II Terdentate and Bidentate Complexes written by Jing Yi and published by . This book was released on 2010 with total page 218 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Design Synthesis Photophysics and Self assembly Study of Platinum II 2 6 bis benzimidazol 2 yl pyridine Complexes with Conjugated Polyelectrolytes and Their Utilization as Luminescent Probes for Molecules of Biological Interest written by 陳啟彥 and published by . This book was released on 2017 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Design Synthesis Photophysics and Self assembly Study of Platinum II Terpyridine Complexes and Their Utilization as Stimuli responsive Smart Materials and Probes for Molecules and Macromolecules of Biological Interest written by Yik-sham Chung (Clive) and published by . This book was released on 2013 with total page 774 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Synthesis Structure and Spectroscopy of Platinum II Diimine Complexes with Potentially Facially coordinating Ligands written by and published by . This book was released on 2005 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Luminescent Platinum ii Complexes Containing Dianionic Tetradentate Ligands Having Mixed Oxygen Nitrogen and Carbon Donor Atoms and Platinum ii Containing Phosphorescent Polymers written by Wai-Yip Tong and published by Open Dissertation Press. This book was released on 2017-01-26 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This dissertation, "Luminescent Platinum(II) Complexes Containing Dianionic Tetradentate Ligands Having Mixed Oxygen, Nitrogen and Carbon Donor Atoms and Platinum(II)-containing Phosphorescent Polymers: Synthesis, Photophysical Properties and Material Applications" by Wai-yip, Tong, 唐煒燁, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Abstract of thesis entitled LUMINESCENT PLATINUM(II) COMPLEXES CONTAINING DIANIONIC TETRADENTATE LIGANDS HAVING MIXED OXYGEN, NITROGEN AND CARBON DONOR ATOMS AND PLATINUM(II)-CONTAINING PHOSPHORESCENT POLYMERS: SYNTHESIS, PHOTOPHYSICAL PROPERTIES AND MATERIAL APPLICATIONS Submitted by TONG WAI YIP for the degree of Doctor of Philosophy at The University of Hong Kong in May 2014 Square planar platinum(II) complexes exhibit rich photophysical properties which are tunable through the structural variation of ligands and can be harnessed for applications in materials science. In this thesis, the great variety of spectroscopic properties of various square planar cyclometalated platinum(II) complexes supported by tetradentate (O DEGREESN DEGREESN DEGREESC and O DEGREESN DEGREESC DEGREESN) and tridentate (C DEGREESN DEGREESN) ligands containing dipyridyl moieties will be highlighted, along with their synthesis, characterization and potential application in organic light emitting diodes (OLEDs). Ind Platinum(II) complexes supported by tetradentate O DEGREESN DEGREESN DEGREESC or O DEGREESN DEGREESN DEGREESC types of ligands (O DEGREESN DEGREESN DEGREESC = 2-(4-(3,5-di-tert-butylphenyl)-6'-phenyl-2,2'- Ind bipyridin-6-yl)phenolate; O DEGREESN DEGREESN DEGREESC = 5,5-dialkyl-2-(6-phenylpyridin-2-yl) indeno[1,2-b]pyridin-9-olate) are emissive in solution at room temperature, with emission maxima tunable from 582 nm to 640 nm and quantum yields up to 0.28. Mechanochromism and the associated luminescence change in [Pt(dihexyl- Ind O DEGREESN DEGREESN DEGREESC)] (Complex 3.6) were found associated with the two different crystal packings revealed by powder X-ray diffraction (PXRD) studies. Fast vapochromic response of [Pt(3-O DEGREESN DEGREESN-2,6-difluoropyridine)] (Complex 3.3) on chloroform or dichloromethane vapours was found to be associated with structural changes in the solid state through PXRD studies. Robust and strongly emissive platinum(II) complexes supported by tetradentate O DEGREESN DEGREESC DEGREESN ligands featuring fused six-five-six membered metallacyclic ring (O DEGREESN DEGREESC DEGREESN = 2-(4-(3,5-di-tert-butylphenyl)-6-(9-(pyridin-2-yl) carbazol-2-yl)pyridin-2-yl)phenol) have been prepared. These platinum(II) complexes are among the most efficient yellow phosphors, with emission maxima ranging from 526 nm to 553 nm and luminescence quantum yields as high as -1 0.47-0.86. A yellow OLED with power efficiency (η ) up to 52 lm W is power demonstrated. In combination with the typical blue emitting iridium(III) 2' bis(4,6-difluorophenyl-pyridinato-N, C ) picolinate (FIrpic), white organic -1 light-emitting diodes (WOLEDs) displayed η up to 61 lm W and reduced power -2 efficiency roll-off at 1000 cd m . Random copolymers with photo-inert backbone poly[(N-vinylcarbazole)-co- ((R-C DEGREESN DEGREESN)Pt)] and poly[(2-(4-tert-butylphenyl)-5-(4-vinylphenyl)-1,3,4- oxadiazole)-co-((R-C DEGREESN DEGREESN)Pt)] (R-C DEGREESN DEGREESN = 3-(6-phenyl-4-(4-vinylphenyl) pyridine-2-yl)-isoquinoline or 3-(4-(4-(dec-9-enyloxy)phenyl)-6-phenylpyridin- 2-yl)isoquinoline) have been synthesized and characterized. Energy transfer between the charge transporting units and emissive (R-C DEGREESN DEGREESN)Pt units was revealed through ICP-MS inve
Download or read book Design Synthesis Photophysics and Self assembly Study of Platinum II Terpyridine Complexes and Their Utilization as Stimuli responsive Smart Materials and Probes for Molecules and Macromolecules of Biological Interest written by Yik-sham Chung (Clive) and published by . This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Radically Different A Themed Issue in Honor of Professor Bernd Giese on the Occasion of His 80th Birthday written by Katharina M. Fromm and published by MDPI. This book was released on 2020-12-02 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue came together thanks to contributions from friends and colleagues of Prof. Bernd Giese on behalf of his 80th birthday on 2 June 2020. Reflecting on the varied interests of Bernd in all areas of chemistry, this issue contains work, including historical work, on inorganic coordination chemistry, nanomaterials, theory, and organic and radical chemistry—Bernd’s core expertise. It is wonderful that so many different publications came together from all over the world, as both review articles and original contributions, making this Special Issue worthwhile reading.
Download or read book Synthesis Characterization and Photophysical Properties of Cyclometalated Platinum II Complexes written by Claudio Pio Mastrocinque and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Platinum II and Gold I Complexes Based on 1 1 bis diphenylphosphino Metallocene Derivatives Synthesis Characterisation and Biological Activity of the Gold Complexes written by and published by . This book was released on with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt: The synthesis of series of 1,2,1' substituted bis(diphenylphosphino)-ruthenocenyl (1-4) and ferrocenyl cis-platinum(II) (5-7) and gold (I) (8-2) complexes are described. Crystal structures of 2 and 4, as well as 5, 6 and 10 confirm the molecular geometry of these ligands and their metal complexes. [partial abstract].
Download or read book Structure Electronic and Photophysical Properties of Platinum ii Biphenyl Complexes Containing 2 20 9 bipyridine and 1 10 phenanthroline Derivatives written by Wei Huang and published by . This book was released on 2010 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: Platinum(II) biphenyl diimine complexes have been synthesized and characterized. Single crystal X-ray structures from seven complexes show two types of configurations about the platinum coordination sphere in the solid state: X and B (butterfly). The two configurations give different circular dichroism spectra (CD) based on their C2 or Cs symmetry. The metal-to-ligand charge transfer (MLCT) bands which occur at ~440 nm are transitions from d orbitals on the platinum metal center to * orbitals of the diimine ligands. This agrees with the time dependant density functional theory (TDDFT) calculations where the lowest unoccupied molecular orbitals (LUMO) are located on diimine ligands. Emission spectra of the complexes can be divided into three groups according to different emission excited states: group I, ligand centered transitions (LC); group II, ligand field transitions (LF) and group III, metal-to-ligand charge transfer (MLCT). Emission profiles from the groups are different from one another: LC transitions have vibronic structures; LF transitions have sharp peaks without vibronic structure and MLCT transitions have a broad peak without vibronic structure. Linear free energy correlations were found between emission maxims, reduction potentials and emission lifetimes with Hammett sp values. The diimine with electron donating substituents have the higher energy emission maxima and the longer emission life time. The diimine with electron withdrawing substituents has the lower energy emission maxima and the shorter emission life time.
Download or read book Design and Synthesis of Platinum II Complexes with Multidentate N donor Ligands written by 傅莉其 and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Design Synthesis and Photophysical Properties of Dinuclear Platinum II Complexes with Varying Bridging and Cyclometalating Ligands written by Subhangi Roy and published by . This book was released on 2018 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt:
