Download or read book Bioassay Techniques for Drug Development written by Atta-ur-Rahman and published by CRC Press. This book was released on 2001-10-04 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of an activity-directed isolation process is to isolate bioactive compounds which may provide structural leads of therapeutic importance. Whereas the traditional process of drug development is long and expensive, simple and rapid bioassays can serve as the starting point for drug discovery. This book presents a range of "bench top" bioassa

Download or read book Beauty in Chemistry written by Luigi Fabbrizzi and published by Springer Science & Business Media. This book was released on 2012-02-22 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Beauty of Chemistry in the Words of Writers and in the Hands of Scientists, by Margherita Venturi, Enrico Marchi und Vincenzo Balzani Living in a Cage Is a Restricted Privilege, by Luigi Fabbrizzi Inner and Outer Beauty, by Kenneth N. Raymond und Casey J. Brown The Mechanical Bond: A Work of Art, by Carson J. Bruns und J. Fraser Stoddart The Beauty of Knots at the Molecular Level, by Jean-Pierre Sauvage und David B. Amabilino

Download or read book Lanthanide Single Molecule Magnets written by Jinkui Tang and published by Springer. This book was released on 2015-04-24 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book begins by providing basic information on single-molecule magnets (SMMs), covering the magnetism of lanthanide, the characterization and relaxation dynamics of SMMs and advanced means of studying lanthanide SMMs. It then systematically introduces lanthanide SMMs ranging from mononuclear and dinuclear to polynuclear complexes, classifying them and highlighting those SMMs with high barrier and blocking temperatures – an approach that provides some very valuable indicators for the structural features needed to optimize the contribution of an Ising type spin to a molecular magnet. The final chapter presents some of the newest developments in the lanthanide SMM field, such as the design of multifunctional and stimuli-responsive magnetic materials as well as the anchoring and organization of the SMMs on surfaces. In addition, the crystal structure and magnetic data are clearly presented with a wealth of illustrations in each chapter, helping newcomers and experts alike to better grasp ongoing trends and explore new directions. Jinkui Tang is a professor at Changchun Institute of Applied Chemistry, Chinese Academy of Sciences. Peng Zhang is currently pursuing his PhD at Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, with a specific focus on the molecular magnetism of lanthanide compounds under the supervision of Prof. Jinkui Tang.

Download or read book Metal Complex DNA Interactions written by Nick Hadjiliadis and published by John Wiley & Sons. This book was released on 2009-03-30 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal ions and metal complexes have long been recognized ascritically important components of nucleic acid chemistry, both inregulation of gene expression and as promising therapeutic agents.Understanding how metal complexes interact with DNA has become anactive research area at the interface between chemistry, molecularbiology and medicine. Metal Complex - DNA Interactions provides a comprehensiveoverview of this increasingly diverse field, presenting recentdevelopments and the latest research with particular emphasis onmetal-based drugs and metal ion toxicity. The text is divided intofour parts: Basic Structural and Kinetic Aspects: includes chapterson sequence-selective metal binding to DNA and thermodynamicmodels. Medical Applications: focuses on anticancer platinumdrugs, including discussions on DNA repair in antitumor effects ofplatinum drugs and photo-dynamic therapy. DNA-Recognition - Nucleases and Sensor: describesprobes for DNA recognition, artificial restriction agents,metallo-DNAzymes for metal sensing applications and metal iondependent catalysis in nucleic acid enzymes. Toxicological Aspects: deals with structural studies ofmercury–DNA interactions, chromium-induced DNA damage andrepair, and the effect of arsenic and nickel on DNAintegrity. This book will be a valuable resource for academic researchersand professionals from a range of pharmaceutical and chemicalindustries, particularly those involved in the development of newand less toxic anticancer metallo-drugs, and in the field ofenvironmental and toxicological chemistry.

Download or read book New Generation Bioinorganic Complexes written by Renata Jastrzab and published by Walter de Gruyter GmbH & Co KG. This book was released on 2016-03-21 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bio-Inorganic compounds are successfully applied as therapeutic agents since decades. Thus, scientist designed new metal complexes bearing biomolecules as ligands, investigating their potential as bioactive and therapeutic agents. This book presents a comprehensive overview on materials design, substance classes and their characterization. This book is compiled for scientists interested in medical application of bioinspired materials.

Download or read book A Search for Antibacterial Agents written by Varaprasad Bobbarala and published by BoD – Books on Demand. This book was released on 2012-09-19 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains precisely referenced chapters, emphasizing antibacterial agents with clinical practicality and alternatives to synthetic antibacterial agents through detailed reviews of diseases and their control using alternative approaches. The book aims at explaining bacterial diseases and their control via synthetic drugs replaced by chemicals obtained from different natural resources which present a future direction in the pharmaceutical industry. The book attempts to present emerging low cost and environmentally friendly drugs that are free from side effects studied in the overlapping disciplines of medicinal chemistry, biochemistry, microbiology and pharmacology.

Download or read book Research Methodology in Chemical Sciences written by Tanmoy Chakraborty and published by CRC Press. This book was released on 2017-03-03 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Methodology in Chemical Sciences provides an eclectic survey of contemporary problems in experimental, theoretical, and applied chemistry. This book covers recent trends in research with the different domain of the chemical sciences. The chapters, written by knowledgeable researchers, provide different insights to the modern-day research in the domain of spectroscopy, plasma modification, and theoretical and computational analysis of chemical problems. It covers descriptions of experimental techniques, discussions on theoretical modeling, and much more.

Download or read book Cage Metal Complexes written by Yan Voloshin and published by Springer. This book was released on 2017-05-11 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fundamental book presents the most comprehensive summary of the current state in chemistry of cage metal complexes. After their previous book “The Encapsulation Phenomenon” (www.springer.com/978-3-319-27737-0) the authors in this book focus on the encapsulation of metal ions by different types of three-dimensional mono- and polynucleating caging ligands. Within these cage metal complexes, (metal) ions can be isolated from external factors. The book provides both a classification of the cage compounds and summaries of synthetic approaches. On that basis the authors then describe the unique chemical and physical properties and the resulting reactivity of the cage compounds, as well as practical and potential applications as potent topological drugs and prodrugs, antifibrillogenic agents, radiodiagnostic and radiotherapeutic compounds, paramagnetic probes, single-molecule magnets, electrocatalysts for hydrogen production, (photo)electronic devices, and many more. Readers will find a well-structured and concise overview, with particular emphasis on a review of synthesis and reactivity of various cage metal complexes, summarizing over 400 literature references, clearly presented in over 300 color schemes and figures.

Download or read book Cadmium From Toxicity to Essentiality written by Astrid Sigel and published by Springer Science & Business Media. This book was released on 2013-02-26 with total page 590 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 11 provides in an authoritative and timely manner in 16 stimulating chapters, written by 40 internationally recognized experts from 11 nations, and supported by more than 2600 references, 35 tables, and over 100 illustrations, many in color, a most up-to-date view on the role of cadmium for life, presently a vibrant research area. MILS-11 covers the bioinorganic chemistry of Cd(II), its biogeochemistry, anthropogenic release into the environment, and speciation in the atmosphere, waters, soils, and sediments. The analytical tools for Cd determination, its imaging in cells, and the use of 113Cd NMR to probe Zn(II) and Ca(II) proteins are summarized, as are Cd(II) interactions with nucleotides, nucleic acids, amino acids, and proteins including metallothioneins. The phytoremediation by Cd(II)-accumulating plants, etc., the toxicology of Cd(II), its damage to mammalian organs, and its role as a carcinogen for humans, are highlighted.

Download or read book Bulletin of the Chemical Society of Japan written by Nihon Kagakkai and published by . This book was released on 2005 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Comprehensive Coordination Chemistry II written by J. A. McCleverty and published by Newnes. This book was released on 2003-12-03 with total page 11845 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprehensive Coordination Chemistry II (CCC II) is the sequel to what has become a classic in the field, Comprehensive Coordination Chemistry, published in 1987. CCC II builds on the first and surveys new developments authoritatively in over 200 newly comissioned chapters, with an emphasis on current trends in biology, materials science and other areas of contemporary scientific interest.

Download or read book Supramolecular Chemistry in the 3rd Millennium written by Catherine E. Housecroft and published by MDPI. This book was released on 2021-08-18 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Special Issue is one of the first for the new MDPI flagship journal Chemistry (ISSN 2624-8549) which has a broad remit for publishing original research in all areas of chemistry. The theme of this issue is Supramolecular Chemistry in the 3rd Millennium and I am sure that this topic will attract many exciting contributions. We chose this topic because it encompasses the unity of contemporary pluridisciplinary science, in which organic, inorganic, physical and theoretical chemists work together with molecular biologists and physicists to develop a systems-level understanding of molecular interactions. The description of supramolecular chemistry as 'chemistry beyond the molecule' (Jean-Marie Lehn, Nobel Lecture and Gautam R. Desiraju, Nature, 2001, 412, 397) addresses the wide variety of weak, non-covalent interactions that are the basis for the assembly of supramolecular architectures, molecular receptors and molecular recognition, programed molecular systems, dynamic combinatorial libraries, coordination networks and functional supramolecular materials. We welcome submissions from all disciplines involved in this exciting and evolving area of science.

Download or read book Gold Chemistry written by Fabian Mohr and published by John Wiley & Sons. This book was released on 2009-04-20 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by world-class authors, this most recent major book on the topic highlights new and current trends as well as future directions. It is comprehensive in its scope, covering all aspects of gold chemistry -- from homogeneous to heterogeneous catalysis, from supramolecular assemblies to sensors and medicinal applications. The result is an invaluable work for both organic and inorganic chemists working in universities and industry, as well as material scientists.

Download or read book Chemical Abstracts written by and published by . This book was released on 1991 with total page 2682 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Single Molecule Magnets written by Malgorzata Holynska and published by John Wiley & Sons. This book was released on 2019-02-11 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Concise overview of synthesis and characterization of single molecule magnets Molecular magnetism is explored as an alternative to conventional solid-state magnetism as the basis for ultrahigh-density memory materials with extremely fast processing speeds. In particular single-molecule magnets (SMM) are in the focus of current research, both because of their intrinsic magnetization properties, as well as because of their potential use in molecular spintronic devices. SMMs are fascinating objects on the example of which one can explain many concepts. Single-Molecule Magnets: Molecular Architectures and Building Blocks for Spintronics starts with a general introduction to single-molecule magnets (SMM), which helps readers to understand the evolution of the field and its future. The following chapters deal with the current synthetic methods leading to SMMs, their magnetic properties and their characterization by methods such as high-field electron paramagnetic resonance, paramagnetic nuclear magnetic resonance, and magnetic circular dichroism. The book closes with an overview of radical-bridged SMMs, which have shown application potential as building blocks for high-density memories. Covers a hot topic – single-molecule magnetism is one of the fastest growing research fields in inorganic chemistry and materials science Provides researchers and newcomers to the field with a solid foundation for their further work Single-Molecule Magnets: Molecular Architectures and Building Blocks for Spintronics will appeal to inorganic chemists, materials scientists, molecular physicists, and electronics engineers interested in the rapidly growing field of study.

Download or read book Experimental and Theoretical Approaches to Actinide Chemistry written by John K. Gibson and published by John Wiley & Sons. This book was released on 2018-03-19 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: A review of contemporary actinide research that focuses on new advances in experiment and theory, and the interplay between these two realms Experimental and Theoretical Approaches to Actinide Chemistry offers a comprehensive review of the key aspects of actinide research. Written by noted experts in the field, the text includes information on new advances in experiment and theory and reveals the interplay between these two realms. The authors offer a multidisciplinary and multimodal approach to the nature of actinide chemistry, and explore the interplay between multiple experiments and theory, as well as between basic and applied actinide chemistry. The text covers the basic science used in contemporary studies of the actinide systems, from basic synthesis to state-of-the-art spectroscopic and computational techniques. The authors provide contemporary overviews of each topic area presented and describe the current and anticipated experimental approaches for the field, as well as the current and future computational chemistry and materials techniques. In addition, the authors explore the combination of experiment and theory. This important resource: Provides an essential resource the reviews the key aspects of contemporary actinide research Includes information on new advances in experiment and theory, and the interplay between the two Covers the basic science used in contemporary studies of the actinide systems, from basic synthesis to state-of-the-art spectroscopic and computational techniques Focuses on the interplay between multiple experiments and theory, as well as between basic and applied actinide chemistry Written for academics, students, professionals and researchers, this vital text contains a thorough review of the key aspects of actinide research and explores the most recent advances in experiment and theory.

Download or read book Studies of Some Novel Coordination Compounds and their Application in Nanoparticle Synthesis written by Nidhi Rai and published by GRIN Verlag. This book was released on 2018-03-07 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific Study from the year 2018 in the subject Chemistry - Anorganic Chemistry, grade: 10, , language: English, abstract: Nanoscience is the study of phenomena exhibited by materials at atomic, molecular and macromolecular levels, of dimensions ranging from a few nanometres to less than a hundred nanometres. In chemistry, this size range has been associated with colloids, micelles, polymer molecules and similar structures. In physical and electrical engineering, nanoscience is often associated with quantum behaviour, and electron behaviour in nanoscale structures. The area of research in the field of nanotechnology is as diverse as physics, chemistry, material science, microbiology, biochemistry and also molecular biology. The interface of nanotechnology in combination with biotechnology and biomedical engineering has emerged with the use of nanoscale structures in diagnosis, gene sequencing, and drug delivery. Nanoparticles have attracted great interest in recent years because of their unique chemical and physical properties, which are different from those of either the bulk materials or single atoms. Nanostructure materials have potential applications in ceramics, optoelectronics and catalysis. Research on the synthesis of nanomaterials using metal complexes as precursors have been less reported. Application of metal complexes as precursors may be helpful to control the physical properties of metal nanoparticles. In the last few years, researchers have characterized the tunable properties by altering the nanostructure size, shape, and chemical composition and have developed reproducible strategies to make nanostructures of desired properties. It has been already proved that by controlling the size of the particle and manipulating surface structures of the semiconductor materials, the electronic, magnetic, mechanical, and chemical properties can be modified to suit a wide range of device application in many fields. The present book deals with the synthesis of Schiff base complexes of Cd(II), Zn(II) and Hg(II) with different sulphur containing ligand and preparation of metal sulphide nanoparticle by the thermal decomposition of complex precursor. During this academic journey four new sulphur containing ligands and their thirty complexes were synthesized. These ligands and complexes were characterized by spectroscopic methods like UV-Vis, FT-IR, 1H-NMR, 13C-NMR, 2D-NMR, FAB-MS / ESI-Ms spectra.