Download or read book Synthesis Characterization and Reactivity of New Nickel II Complexes Towards Urea and Carbon Dioxide written by William Seals and published by . This book was released on 2012 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Synthesis Characterization and Reactivity of Various Imine Nickel II Complexes written by Daniel Beagan and published by . This book was released on 2016 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nickel Catalysis in Organic Synthesis written by Sensuke Ogoshi and published by John Wiley & Sons. This book was released on 2020-03-09 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive reference to nickel chemistry for every scientist working with organometallic catalysts Written by one of the world?s leading reseachers in the field, Nickel Catalysis in Organic Synthesis presents a comprehensive review of the high potential of modern nickel catalysis and its application in synthesis. Structured in a clear and assessible manner, the book offers a collection of various reaction types, such as cross-coupling reactions, reactions for the activation of unreactive bonds, carbon dioxide fixation, and many more. Nickel has been recognized as one of the most interesting transition metals for homogeneous catalysis. This book offers an overview to the recently developed new ligands, new reaction conditions, and new apparatus to control the reactivity of nickel catalysts, allowing scientists to apply nickel catalysts to a variety of bond-forming reactions. A must-read for anyone working with organometallic compounds and their application in organic synthesis, this important guide: -Reviews the numerous applications of nickel catalysis in synthesis -Explores the use of nickel as a relatively cheap and earth-abundant metal -Examines the versatility of nickel catalysis in reactions like cross-coupling reactions and CH activations -Offers a resource for academics and industry professionals Written for catalytic chemists, organic chemists, inorganic chemists, structural chemists, and chemists in industry, Nickel Catalysis in Organic Synthesis provides a much-needed overview of the most recent developments in modern nickel catalysis and its application in synthesis.

Download or read book Synthesis Characterization and Reactivity of Ni II Complexes Stabilized by an Intramolecular Hydrogen Bonding Network written by Darla A. Powell-Jia and published by . This book was released on 2010 with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metalloenzymes are able to perform a wide variety of difficult chemical transformations in a highly selective and efficient manner. The ability of metal complexes to perform a particular chemical reaction is dependant on the properties of the primary and secondary coordination environments. Development of transition metal complexes that catalyze the formation of organic compounds in a selective and highly efficient manner is of interest to synthetic chemists. Advancement in this area of research requires studies aimed at developing ligands that will give desirable properties upon binding to a metal ion. Using interactions present in biological systems, the ligands in this study have been developed to investigate the effects of the primary coordination sphere as well as hydrogen bonding interactions on complex formation as well as reactivity. Chapter 2 discusses the synthesis of terminal monomeric NiII-OH complexes with H41R. The hydroxo ligand is stabilized by two intramolecular hydrogen bonding interactions and the source of the hydroxo ligand was confirmed to be water. Attempts to deprotonate the NiII-OH complex to form a NiII-oxo complex were unsuccessful. Treating the NiII-OH complexes with KOtBu afforded the alkoxide substituted product. NiII-siloxide complexes were isolated upon reaction of NiII-OH with K[N(TMS)2]. Chapter 3 features the synthesis of a series of Ni(II) complexes with H2pmb, which contains two carboxyamido units appended from pyridine rings. Four Ni(II) complexes were synthesized and structurally characterized. It was determined that the carboxyamido groups either provided intramolecular H-bonds or the carbonyl oxygen can bind directly to the metal center. Chapter 4 explores the electrochemistry of the Ni(II) complexes characterized in Chapter 3. Based upon the observed reduction potentials, the reduction chemistry of [NiIIH2pmb(Cl)2] was explored. Further reactivity of the reduced species was also explored with dioxygen. Preliminary reactivity studies will also be discussed.

Download or read book Synthesis Characterization and Reactivity of Nickel Complexes with N Donor Olefinic and Macrocyclic Ligands written by Lars Valentin and published by . This book was released on 2014 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Sulfur rich Nickel Complexes written by Patti Joann Riggs and published by . This book was released on 1990 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Synthesis Characterization and Reactivity of Nickel 2 pyridylphosphine Complexes written by and published by . This book was released on 2000 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Energy Research Abstracts written by and published by . This book was released on 1990 with total page 980 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Synthesis and Characterization of Nickel II Complexes of a Hydrotrispyrazolylborate Ligand and of Novel Phosphinetrithiol Ligands written by Weihong Zhang and published by . This book was released on 1990 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Synthesis and Characterization of Nickel II Complexes of a Hydrotrispyrazolylborato Ligand and of the Thiosalicylato Ligand written by Weibin Chen and published by . This book was released on 1994 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Part I The Electrocatalytic Reduction of Carbon Dioxide Using Macrocycles of Nickel and Cobalt Part II The Preparation Characterization and Reaction Chemistry of Some New Iridium Bis tertiary Phosphine Complexes written by Barbara Jo Fisher and published by . This book was released on 1983 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Synthesis and Characterization of Mixed ligand Nickel II Complexes Possessing a Hydrotrispyrazolylborato Ligand written by Subo Liao and published by . This book was released on 1992 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Synthesis and Characterization of Nickel II Complexes with 1 4 7 10 tetrabenzyl 1 4 7 10 tetraazacyclododecane written by George A. Kalligeros and published by . This book was released on 1971 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Synthesis Characterization and Biological Studies of Nickel II Complexes Containing Thiosemicarbazone and Thiourea Derivatives written by Hana Bashir Mohammed Shawish and published by . This book was released on 2014 with total page 510 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Nickel II Pincer Complexes Supported by 2 6 Bis 3 5 Ditolyl 2 Pyrrolyl Pyridine written by Abhijit Pramanik and published by . This book was released on 2015 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ni(II) pincer complexes are among the most important and useful compounds in homogeneous catalysis. Significant advancement has been made in this field in recent years. Many Ni(II) pincer complexes have been prepared and utilized in various catalytic reactions e.g. cross coupling reactions, C-H activation, carbon dioxide activation etc. Still, nickel(II) complexes supported by the pincer ligand with three nitrogen donors are relatively less explored and catalytic applications with those complexes are scarce in literature. This thesis describes the synthesis of a new pyrrolyl pyridine based pincer ligand and its Ni(II) complexes. The pyrrolyl pyridine pincer ligand, a relatively new class of dianionic, tridentate, nitrogen-based ligands in coordination chemistry, was prepared starting with a modified method for the synthesis of pyrrolyl pyridine. This modified procedure is simpler, less time consuming making it cheaper than the classical method and provides 2,6-bis(3,5-ditolyl-2-pyrrolyl)pyridine in good yields. Reaction of its potassium salt with Ni(OTf)2 resulted in three different stable nickel(II) pincer complexes. The novel nickel(II) pincer complexes were fully characterized by 1H NMR spectroscopy, 13C NMR spectroscopy, infrared spectroscopy and high resolution mass spectrometry. The X-ray crystal structures of the new ligand and metal complexes have been described.

Download or read book Synthesis Characterization and Biological Studies of Nickel Ii and Zinc Ii Complexes with Mono and Di Bromo Substituted Schiff Base Ligands written by Bussaba Pinchaipat and published by . This book was released on 2020 with total page 30 pages. Available in PDF, EPUB and Kindle. Book excerpt: Transition metal complexes of nickel(II) and zinc(II) with 5-bromo- N -(8-quinolyl)salicylaldimine (HqsalBr, HL 1 ) and 3,5-dibromo- N -(8-quinolyl)salicylaldimine (HqsalBr 2 , HL 2 ) have been synthesized and successfully characterized using several techniques: IR, 1 H-NMR, mass spectrometry and thermogravimetric analysis (TGA). The molecular structures of nickel(II) and zinc(II) complexes with HL 2 were determined by single crystal X-Ray crystallography. Ligands HL 1 and HL 2 both act as a tridentate ligand and coordinate to metal ion center via deprotonated hydroxyl oxygen atom, nitrogen of azomethine functional group and nitrogen of quinoline substituent. The interaction of these complexes with DNA was investigated using calf thymus DNA (CT-DNA) in which the studies by electronic absorption and luminescence titrations reveal that DNA binding mode of the complexes is intercalation. All the synthesized complexes provide great values of binding constant (K b ) and these results are consistent with the quenching capability defined by quenching constant values (K q ). Amongst the synthesized complexes, zinc(II) with ligand HL 2 complex, [Zn(qsalBr) 2 ], exhibits the most superior ability in the interaction with CT-DNA and the verification mode of binding by the competitive reaction with ethidium bromide (EB) also indicates the strongest intercalation by such complex. Additionally, ligands and complexes were also examined in anti-lung cancer activity against A549 cell line and compared with standard compounds, Etoposide and Cisplatin.

Download or read book The Development of New Direct and Asymmetric Ni II Catalysed Carbon carbon Bond Forming Reactions and Their Application to Total Synthesis written by Stuart Kennington and published by . This book was released on 2021 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This thesis focuses on the search for new methodologies for the direct, stereoselective and catalytic formation of carbon-carbon bonds through the formation of chiral nickel(II) enolate species and the application of such methods to the synthesis of natural products. The project starts with the stereocontrol coming from chiral auxiliaries, developed first by Evans and then later by Crimmins and Nagao, following the previous experience and expertise of the research group. These auxiliaries have proved to be a reliable and high yielding option to afford excellent levels of stereocontrol in various reactions. Furthermore, they can be removed after such processes to leave enantiopure synthons. However, they do have their drawbacks, one being the inability of synthesising all of the available stereoisomers from one starting material. To combat this issue, the second part of the thesis is centred around the development of a new methodology based on achiral starting materials (scaffolds) with chiral nickel(II) complexes, which both enable the reaction and control its stereochemical outcome.In the first Chapter, methods previously developed in the group were applied to the synthesis of a fragment of the marine sponge macrolide Peloruside A, which has shown to have anticancer activity, especially against leukaemia. Three key steps involve reactions based on the use of chiral auxiliaries that had been developed in the group: a nickel catalysed reaction with trimethyl orthoformate, a titanium-mediated acetate aldol reaction, and a titanium-mediated addition of an acetate enolate to an acetal. The overall yield of the synthesis of the target fragment C9-C19 was 24% over 14 steps.Chapter 2 presents a new reaction based on the addition of enolates, generated from chiral N-acyl thiazolidinethiones with an achiral nickel(II) complex, to stable carbocationic salts. This alkylation reaction was first thoroughgoingly optimised and later applied to a large range of substrates with wide success. Moreover, it was applied to a highly challenging electrophile successfully which lead to the discovery of a reversible alkylation process. The products were also transformed via the removal of the auxiliary to leave a variety of functional groups.In Chapter 3 the stereocontrol is passed from the starting material to the catalyst in an ambitious advancement of the group's chemistry. After an extensive study of potential achiral scaffolds to provide the platform for the reactions and chiral diphosphine ligands to provide the enantiocontrol, we observed the best scaffold was the 6-memberd thiazinanethione structure and the best ligand DTBM-SEGPHOS®. We were able to apply this methodology to the reaction of: trimethyl orthoformate (an oxocarbenium precursor), tropylium tetrafluoroborate (a cationic salt), a diaryl methyl ether (a carbenium precursor), and also a more complex diaryl ketal electrophile with high yields and exceptional control over the one stereocentre formed. Furthermore, using a dimethyl acetal we were able to exert some control over the relative configuration of two stereocentres whilst maintaining exceptional enantioselectivity. Calculations and elucidation of the configuration of the new stereocentre formed support our hypothesis for the mechanism for such a process. We also demonstrated the ease with which the scaffold can be removed and were able to synthesise a wide variety of synthons with differing functional groups. Finally, we were able to scale up and apply the methodology to the synthesis of Peperomin D, a five membered lactone containing two stereocentres.Finally, in the last Chapter we present a new methodology for the asymmetric aldol reaction of N-acyl thiazinanethiones with aromatic aldehydes catalysed by a chiral nickel (II) complex, which involves the simultaneous silyl protection of the adducts. This new reaction proceeds through an open transition state and leads to the anti-aldol products. We were able to optimise the reaction to achieve a high diastereoselectivity, exceptional enantioselectivity, and excellent yield. Furthermore, we were able to apply the conditions to various aromatic aldehydes and N-acyl thiazinanethiones. Finally, the scope of the reaction was expanded to three different electrophiles, opening new lines of investigation" -- TDX.