Download or read book Survival February March 2024 written by The International Institute for Strategic Studies (IISS) and published by Taylor & Francis. This book was released on 2024-02-09 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: Survival, the IISS’s bimonthly journal, challenges conventional wisdom and brings fresh, often controversial, perspectives on strategic issues of the moment. In this issue: Franz-Stefan Gady and Michael Kofman highlight the pitfalls of grafting a Western manoeuvre-oriented approach to war onto the Russia–Ukraine conflict Irene Mia examines the chasm between Javier Milei’s dramatic rhetoric and the domestic and international obstacles he faces to changing Argentina’s foreign and economic policies Edoardo Campanella and John Haigh outline the necessity of meaningful dialogue between the West and China to prevent the internet’s fragmentation John Raine assesses the geopolitical trends that the Gaza war has set in motion and the issues they create for Ukraine’s defence against Russia And seven more thought-provoking pieces, as well as our regular Book Reviews and Noteworthy column. Editor: Dr Dana Allin Managing Editor: Jonathan Stevenson Associate Editor: Carolyn West Editorial Assistant: Conor Hodges
Download or read book Survival February March 2022 written by The International Institute for Strategic Studies (IISS) and published by Taylor & Francis. This book was released on 2023-04-21 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: Survival, the IISS’s bimonthly journal, challenges conventional wisdom and brings fresh, often controversial, perspectives on strategic issues of the moment. In this issue: · The Ukraine crisis: Robert Hunter argues that the most important requirement of successful US-led negotiations with Russia is that Moscow demonstrate that it is prepared to be a responsible international actor · Erin Sikorsky contends that climate change should have a larger role in the day-to-day national-security agendas of the United States and other countries · Stephan Frühling and Andrew O’Neil warn that current US debates about no first use tend to underplay the broader alliance implications of any shift in US nuclear policy · Rahul Roy-Chaudhury and Kate Sullivan de Estrada assess that, given the 2021 US FONOP targeting India, Washington and New Delhi need to better manage their diverse positions on global governance, especially in the maritime domain · Nien-chung Chang-Liao warns that pragmatism in Chinese foreign policy is waning and considers why Chinese diplomats have become so aggressive And nine more thought-provoking pieces, as well as our regular Book Reviews and Noteworthy column. Editor: Dr Dana Allin Managing Editor: Jonathan Stevenson Associate Editor: Carolyn West Assistant Editor: Jessica Watson
Download or read book The Military Balance 2022 written by The International Institute for Strategic Studies (IISS) and published by Routledge. This book was released on 2022-02-14 with total page 504 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published each year since 1959, The Military Balance is an indispensable reference to the capabilities of armed forces across the globe. It is used by academia, the media, armed forces, the private sector and government. It is an open-source assessment of the military forces and equipment inventories of 171 countries, with accompanying defence economics and procurement data. Alongside detailed country data, The Military Balance assesses important defence issues, by region, as well as key global trends, such as in defence technology and equipment modernisation. This analysis is accompanied by full-colour graphics, including maps and illustrations. With extensive explanatory notes and reference information, The Military Balance is as straightforward to use as it is extensive. The 2022 edition is accompanied by a fullcolour wall chart illustrating security dynamics in the Arctic.
Download or read book Community series in Progress of Allo and Xeno transplantation Facilitating the Initial Xeno Kidney and Islet Clinical Trials volume II written by Lisha Mou and published by Frontiers Media SA. This book was released on 2024-06-21 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: Owing to the availability of more advanced genetically engineered pigs, more immunological and physiological barriers have been overcome. With the results of pig organ xenotransplantation steadily improving, consideration is now given to the first clinical trials of xenotransplantation. The first step is kidneys, but possibilities also exist in pig islet transplantation for patients with diabetes.
Download or read book Systemic Inflammation in Severe Infectious Diseases written by Praveen Papareddy and published by Frontiers Media SA. This book was released on 2024-09-30 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hospital-acquired infections are common and often result in life-threatening complications, mostly facing critically ill patients in the intensive care unit. Patients with hospital-acquired infections may die from bacteremia/fungal/viral infection or hyperinflammatory complications because of an uncontrolled over-activation of the innate immune system with pathological levels of circulating proinflammatory cytokines, or from multiorgan failure. In addition to eliciting a robust inflammatory response, it paradoxically renders the host in an immunocompromised state at the late stage of the disease progression. Severe infectious diseases, including sepsis and septic shock are among the most common reasons for death in hospitals. Sepsis is an infection-induced syndrome characterized by a generalized inflammatory state and represents a frequent complication in surgical patients and in immunocompromised patients. Sepsis is a common, expensive, and frequently associated with a fatal outcome. Every 3 to 4 seconds somebody dies with sepsis, and it is one of the leading causes of death worldwide.
Download or read book Advances toward improved understanding and treatment of uncommon ovarian cancer types and subtypes written by Robb Hollis and published by Frontiers Media SA. This book was released on 2024-10-22 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ovarian cancer is an umbrella term for a collection of distinct disease entities (histotypes). Until now, the majority of research has focussed on the most common histotype, high-grade serous ovarian carcinoma (HGSOC), which accounts for 70% of cases. The less common histotypes – including endometrioid, clear cell, mucinous, low-grade serous, carcinosarcoma, and non-epithelial histotypes – have received far less research attention. Accordingly, while major advances in our understanding of HGSOC have led to molecularly-directed therapies that improve patient outcomes, progress in less common histotypes has lagged behind. Notably, many of the uncommon histotypes demonstrate resistance to conventional chemotherapy regimens, and their inherent biological differences suggest most are unlikely to respond to emerging molecular therapeutics designed to target the biology of common ovarian cancer types.
Download or read book Gliomas microenvironment New drug entities mechanisms of action molecular biomarkers and drug delivery strategies written by Célia Cabral and published by Frontiers Media SA. This book was released on 2024-07-26 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gliomas are neoplasms originating in glial cells, the most malignant and frequent primary tumors of the Central Nervous System (CNS), representing approximately 40-50% of all intracranial tumors. Following the World Health Organization (WHO) guidelines, gliomas are classified into grades I-IV, regarding their malignancy degree. The latest report from WHO on CNS tumors considers that glioblastoma (GB), a grade IV adult-type diffuse glioma comprising isocitrate dehydrogenase (IDH)-wildtype tumors. Despite all efforts to improve patient survival and quality of life, the median survival remains lower due to the lack of effective diagnostic tools, poor prognosis, and limited therapeutic options. Regarding this, the design of novel treatment strategies is of the utmost importance. This can be by either the discovery of new medicines (for example synthetic compounds), repurposing known drugs or exploring novel strategies of drug delivery by nanotechnological platforms to improve treatment response and long-term survival of patients. Inter and intra-tumor heterogeneity mainly contribute to the poor prognosis and treatment efficacy. Therefore, exploiting tumor microenvironment (TME) and understanding GB’s cellular and molecular aspects are fundamental to developing more effective and better-tolerated personalized therapies. Thus, addressing physiological mechanisms involved in cancer development, progression and recurrence is crucial. Concerning this, our goal with this research topic is to share the latest advances in tumor-specific therapies for gliomas, especially GB, as well as to provide experimental validation of new bioactive molecules and their antitumor mechanism of action. Authors are invited to submit original research, review articles and systematic reviews covering, but not restricted to, the following topics: 1) Novel targeted therapies; 2) Mechanism of action and affected signaling pathways; 3) Repurposing drugs; 5) New chemical entities; 6) Pharmaceutical nanotechnology; 7) Drug delivery systems; 8) Preclinical and clinical studies of therapeutic molecules; 9) Potential molecular biomarkers to targeted therapies using proteomics or transcriptomics.
Download or read book Contraband Cultures written by Jennifer Cearns and published by UCL Press. This book was released on 2024-09-17 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contraband Cultures presents narratives, representations, practices and imaginaries of smuggling and extra-legal or informal circulation practices, across and between the Latin American region (including the Caribbean) and its diasporas. Countering a fetishizing and hegemonic imaginary (typically stemming from the Global North) of smuggling activity in Latin America as chaotic, lawless, violent and somehow ‘exotic’, this book reframes such activities through the lenses of kinship, political movements, economic exchange and resistance to capitalist state hegemony. The volume comprises a broad range of chapters from scholars across the social sciences and humanities, using various methodological techniques, theoretical traditions and analytic approaches to explore the efficacy and valence of ‘smuggling’ or ‘contraband’ as a lens onto modes of personhood, materiality, statehood and political (dis)connection across Latin America. This material is presented through a combination of historic documentation and contemporary ethnographic research across the region to highlight the genesis and development of these cultural practices whilst grounding them in the capitalist and colonial refashioning of the entire region from the sixteenth century to the present day.
Download or read book Blue Foods Security and Sustainability written by Ruijie Zhang and published by Frontiers Media SA. This book was released on 2024-10-09 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Blue foods — aquatic foods captured or farmed in marine and freshwater systems — play a key role in feeding and nourishing the world by providing highly accessible and affordable sources of protein and micronutrients for over 3.2 billion people and supporting the jobs of 58.5 million people, and the livelihoods of 600 million people. In the past 71-year period, blue foods have significantly expanded from 19.9 million tons in 1950 to 214 million tons in 2020. Yet, with 811 million people suffering from hunger and 3 billion people unable to afford a healthy diet, blue food production is poised to continue to expand in the future. However, the expansion of aquaculture and fisheries has also raised a series of ecological and environmental issues, such as biodiversity loss, environmental pollution (plastic pollution, antibiotic pollution, nitrogen and phosphorus emissions, etc.), land and freshwater use, overfishing, habitat degradation etc. In parallel, the continuously growing demand for blue food has been challenged by unprecedented environmental changes, such as climate change, ocean acidification, water pollution (microplastics, antibiotics, persistent pollutants), etc. But compared to other animal-sourced foods, blue food can remain an imperative component of sustainable food system solutions by reducing the environmental footprint and relieving pressure on overburdened terrestrial systems. Therefore, it is important to understand the challenges and priorities of the blue food transformation in order to jointly promote food safety and environmental sustainability.
Download or read book Hawke s Green Beret Survival Manual written by Mykel Hawke and published by Running Press Adult. This book was released on 2011-12-20 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: The perfect home-reference book for both seasoned outdoorsmen and average citizens to learn comprehensive outdoor survival techniques. This practical survival guide from U.S. Special Forces Captain and outdoor survival expert Mykel Hawke includes illustrated instruction on: shelter and water food and fire tools and medicine navigation and signaling survival psychology Hawke's engaging style and matter-of-fact attitude-not to mention his incredible resume in the survival arena-elevates this book above its competition.
Download or read book The State of Food Security and Nutrition in the World 2024 written by Food and Agriculture Organization of the United Nations and published by Food & Agriculture Org. [Author] [Author]. This book was released on 2024-07-23 with total page 286 pages. Available in PDF, EPUB and Kindle. Book excerpt: Six years from 2030, hunger and food insecurity trends are not yet moving in the right direction to end hunger and food insecurity (SDG Target 2.1) by 2030. The indicators of progress towards global nutrition targets similarly show that the world is not on track to eliminate all forms of malnutrition (SDG Target 2.2). Billions of people still lack access to nutritious, safe and sufficient food. Nevertheless, progress in many countries provides hope of the possibility of getting back on track towards hunger and malnutrition eradication. Implementing the policies, investments and legislation needed to revert the current trends of hunger, food insecurity and malnutrition requires proper financing for food security and nutrition. Despite a broad agreement on the urgent need to increase financing for food security and nutrition, the same cannot be said for a common understanding regarding how this financing should be defined and tracked. The report provides a long-awaited definition of financing for food security and nutrition and guidance for its implementation. There are recommendations regarding the efficient use of innovative financing tools and reforms to the food security and nutrition financing architecture. Establishing a common definition of financing for food security and nutrition, and methods for its tracking, measurement and implementation, is an important first step towards sustainably increasing the financing flows needed to end hunger, food insecurity and all forms of malnutrition, and to ensure access to healthy diets for all, today and tomorrow.
Download or read book Media Compass written by Aljosha Karim Schapals and published by John Wiley & Sons. This book was released on 2024-09-04 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: An extensive and inclusive account of the media environments of 45 countries worldwide In Media Compass: A Companion to International Media Landscapes, an international team of prominent scholars examines both long-term media systems and fluctuating trends in media usage around the world. Integrating country-specific summaries and cross-cutting studies of geopolitical regions, this interdisciplinary reference work describes key elements in the political, social, demographic, cultural, and economic conditions of media infrastructures and public communication. Enabling the mapping of media landscapes internationally, Media Compass contains up-to-date empirical surveys of individual countries and regions, as well as cross-country comparisons of particular areas of public communication. 45 entries, each guiding readers from a general summary to a more in-depth discussion of a country’s specific media landscape, address formative conditions and circumstances, historical background and development, current issues and challenges, and more. Designed to facilitate quick lookup of individual entries, as well as comparative readings of a country’s position in the wider media environment, Media Compass: A Companion to International Media Landscapes is an invaluable addition to libraries and institutions of higher education, and a must-read volume for students, educators, scholars, and practitioners working in communication and media studies, journalism, and media production.
Download or read book Who Will Defend Europe written by Keir Giles and published by Hurst Publishers. This book was released on 2024-10-24 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Who will defend Europe? The answer should be obvious: Europe should be able to defend itself. Yet, for decades, most of the continent enjoyed a defence holiday, outsourcing protection to the United States while banking an increasingly illusory ‘peace dividend’. Now, after three decades of reducing armed forces and drawing down defence industries, Europe finds itself close to unprotected—while Russia is intent on continuing its war of expansion, and the US is distracted and divided. In this urgent, vital book, Keir Giles lays out the stark choices facing leaders and societies as they confront the return of war in Europe. He explains how the West’s unwillingness to confront Russia has nurtured the threat, and that Putin’s ambition puts the whole continent at risk. He assesses the role and deficiencies of NATO as a guarantor of hard security, and whether the EU or coalitions of the willing can fill the gap. Above all, Giles emphasises the need for new leadership in defence of the free world after the US has stepped aside— and warns that the UK’s brief moment of setting the pace for Europe has already been squandered.
Download or read book New Mechanisms for Anti Cancer Drugs written by Ayaz Shahid and published by Frontiers Media SA. This book was released on 2024-04-15 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is the second leading cause of death. Every year, many anticancer drug candidates are discovered and synthesized, but the major challenge lies in identifying, characterizing and evaluating their efficacy. The aim of this Research Topic, "New Mechanisms for Anti-Cancer Drugs" is to collect a group of publications focused on novel chemical compounds exhibiting new modes of actions and/or new target proteins to fulfill their cytotoxic activity on cancer cells. In this context, we will also be pleased to consider studies on drug repurposing, including approved, discontinued, and shelved drugs, when anti-cancer activity results from an unexpected mode of action.
Download or read book Survival of the Friendliest written by Brian Hare and published by Random House. This book was released on 2020-07-14 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: A powerful new theory of human nature suggests that our secret to success as a species is our unique friendliness “Brilliant, eye-opening, and absolutely inspiring—and a riveting read. Hare and Woods have written the perfect book for our time.”—Cass R. Sunstein, author of How Change Happens and co-author of Nudge For most of the approximately 300,000 years that Homo sapiens have existed, we have shared the planet with at least four other types of humans. All of these were smart, strong, and inventive. But around 50,000 years ago, Homo sapiens made a cognitive leap that gave us an edge over other species. What happened? Since Charles Darwin wrote about “evolutionary fitness,” the idea of fitness has been confused with physical strength, tactical brilliance, and aggression. In fact, what made us evolutionarily fit was a remarkable kind of friendliness, a virtuosic ability to coordinate and communicate with others that allowed us to achieve all the cultural and technical marvels in human history. Advancing what they call the “self-domestication theory,” Brian Hare, professor in the department of evolutionary anthropology and the Center for Cognitive Neuroscience at Duke University and his wife, Vanessa Woods, a research scientist and award-winning journalist, shed light on the mysterious leap in human cognition that allowed Homo sapiens to thrive. But this gift for friendliness came at a cost. Just as a mother bear is most dangerous around her cubs, we are at our most dangerous when someone we love is threatened by an “outsider.” The threatening outsider is demoted to sub-human, fair game for our worst instincts. Hare’s groundbreaking research, developed in close coordination with Richard Wrangham and Michael Tomasello, giants in the field of cognitive evolution, reveals that the same traits that make us the most tolerant species on the planet also make us the cruelest. Survival of the Friendliest offers us a new way to look at our cultural as well as cognitive evolution and sends a clear message: In order to survive and even to flourish, we need to expand our definition of who belongs.
Download or read book The Importance of the Body Mind Relationship in Mental Functioning and Development of Body Focused Disorders in Adolescence volume II written by Stefania Cella and published by Frontiers Media SA. This book was released on 2024-06-28 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection is Volume II of the Research Topic The Importance of the Body-Mind Relationship in Mental Functioning and Development of Body-Focused Disorders in Adolescence. Adolescence is a critical period when the conflict between the body and mind becomes particularly pronounced due to the physical changes associated with puberty. These pubescent transformations can affect body image and the perception of self, necessitating a renegotiation of the relationship between body and mind. Failure to navigate this process successfully can lead to dissociation from the sexual body, resulting in feelings of alienation, hatred, disinvestment, and even self-destructive behaviors such as eating disorders, self-injury, and suicide.
