Download or read book Survey Report on the Aging Nervous System written by and published by . This book was released on 1975 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Brain Aging written by David R. Riddle and published by CRC Press. This book was released on 2007-04-19 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur
Download or read book Model Systems of Development and Aging of the Nervous System written by Antonia Vernadakis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: The last decade has generated a multitude of studies using in vitro model systems to explore growth and differentiation of the nervous system. Although the findings have been exciting and have revealed unique properties of neural cells, considerable concern continues to be expressed regarding the significance of in vitro findings in terms of their applicability to in vivo biological events. To examine this issue further, a group of scientists pre sented and discussed their findings at a conference sponsored by the Institute of Developmental Neuroscience and Aging held in Crete, Greece, 26-29 May 1985. The conference was cosponsored by the University of Crete and was generously supported by the Ministry of Research and Technology of Greece, Tourism Organization of Greece, and also Sandoz and FIDIA. The Directors of the Institute of Developmental Neuroscience and Aging are indebted to these Institutions for their support. For the success of this conference, the Directors owe much to Drs. Eleni Fleischer-Lambropoulos and Yiannis Tsouderos, who spent countless hours in making arrangements so that the participants would have not only a scientific, but also a unique cultural, experience. Several chapters of this book focus on the complex phenomena of neurogenesis and gliogenesis, and the modulation of neuronal differentiation. The concept that neuronal differentiation has both genetic and epigenetic components is documented by elegant studies using both in vitro cultured cells and neurons transplanted in vivo.
Download or read book The Aging Mind written by National Research Council and published by National Academies Press. This book was released on 2000-04-18 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Possible new breakthroughs in understanding the aging mind that can be used to benefit older people are now emerging from research. This volume identifies the key scientific advances and the opportunities they bring. For example, science has learned that among older adults who do not suffer from Alzheimer's disease or other dementias, cognitive decline may depend less on loss of brain cells than on changes in the health of neurons and neural networks. Research on the processes that maintain neural health shows promise of revealing new ways to promote cognitive functioning in older people. Research is also showing how cognitive functioning depends on the conjunction of biology and culture. The ways older people adapt to changes in their nervous systems, and perhaps the changes themselves, are shaped by past life experiences, present living situations, changing motives, cultural expectations, and emerging technology, as well as by their physical health status and sensory-motor capabilities. Improved understanding of how physical and contextual factors interact can help explain why some cognitive functions are impaired in aging while others are spared and why cognitive capability is impaired in some older adults and spared in others. On the basis of these exciting findings, the report makes specific recommends that the U.S. government support three major new initiatives as the next steps for research.
Download or read book From Brain to Body The Impact of Nervous System Declines on Muscle Performance in Aging written by Brian C. Clark and published by Frontiers Media SA. This book was released on 2015-12-18 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Download PDF Download EPUB The deterioration of skeletal muscle performance (e.g., declines in muscle strength and motor performance) with advancing age has long been anecdotally recognized as Shakespeare pointed out nearly a half millennium ago in his monologue The Seven Ages of Man, and has been of scientific interest for well over a century. Over the past several decades the scientific and medical communities have recognized that reduced skeletal muscle performance is a debilitating and life threatening condition in the elderly. For example, the age-associated loss of muscle strength, as well as impairment in the ability to finely control movement, is highly associated with physical disability and difficulty performing activities of daily living. While the nervous system is widely recognized for its role in controlling skeletal muscle during motor function, its role in determining the performance characteristics of aged skeletal muscle has largely been understudied. Historically, it was believed that these reductions in muscle performance were primarily resultant of age-associated adaptations in skeletal muscle (e.g., muscle atrophy). However, aging is associated with widespread qualitative and quantitative changes in both the central and peripheral nervous systems that are likely to influence numerous aspects of muscle performance, such as muscle strength, fatigue, and motor control, as well as mobility. In this research topic, we sought to examine a broad range of issues surrounding: 1) the age-related changes in nervous system anatomical, physiological, and biochemical changes in the central and/or peripheral nervous systems; 2) the functional role of these nervous system changes in contributing to altered skeletal muscle performance and/or mobility; and 3) physical and pharmacologic interventions that act via the nervous system to enhance muscle performance and/or mobility. Researchers and academicians engaged in aging, neuroscience, and/or applied physiology research focused within the scope of this research topic, were encouraged to contribute an original research article, review article, clinical case study, hypothesis and theory article, method article, opinion article, or technology report to this research topic. Herein, we present a series of outstanding articles within this scope of work, including a last minute addition article from Wiesmeier, Dalin and Maurer that is not mentioned in the editorial, that we hope will help to vertically advance the intersecting fields of aging/geriatrics and neuroscience. Lastly, as the editors, we wish to thank all article contributors and peer reviewers for their efforts in contributing to this Research Topic journal issue/book. Additionally, we would like to thank people everywhere who volunteer their time and body for human subjects research studies, such that are presented herein. It is the wonderful individuals who are willing to participate in experiments that make scientific exploration and health and medical advancements possible.
Download or read book Geriatric Neurology written by Anil K. Nair and published by John Wiley & Sons. This book was released on 2014-03-06 with total page 760 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging affects neurological function leading to neurological disease As society grows older, so do the neurological problems associated with aging. These can be new neurological deficits due to the aging process itself, or the effect of aging on already existing neurological conditions. Neurologists will spend increasing amounts of time managing patients with age-related neurological complications. Geriatric Neurology brings together the wisdom of world-leading experts. They have crafted a new textbook to define this emerging subspecialty from basic science through clinical assessment and medical management to social aspects of patient care. Geriatric Neurology covers: The aging brain in neurology Assessment of the geriatric neurology patient Neurological conditions in the elderly Therapeutics for the geriatric neurology patient Management issues beyond therapeutics Comprehensive in scope but with practical focus for effective patient care, Geriatric Neurology provides top-of-class guidance for the management of elderly patients with neurological disorders.
Download or read book Functional Neurobiology of Aging written by Patrick R. Hof and published by Elsevier. This book was released on 2001-01-11 with total page 989 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some well-known age-related neurological diseases include Parkinson's disease, Alzheimer's disease, deafness, and blindness. Even more common are the problems of aging which are not due to disease but to more subtle impairments in neurobiological systems, including impairments in vision, memory loss, muscle weakening, and loss of reproductive functions, changes in body weight, and sleeplessness. As the average age of our society increases, diseases of aging continue to become more common, and conditions associated with aging need more attention by doctors and researchers. In 1991, patients over the age of 65 saw their doctors an average of eight times per year. Research funding is provided by the Neuroscience and Neuropsychology of Aging (NNA) Program, which is run by the National Institute on Aging. This book offers a comprehensive overview of all topics related to functional impairments which are related to the aging brain and nervous system. It is organized according to four general functions: movement, senses, memory, and neuroendocrine regulation. Written by the leading researchers in the field, this comprehensive work addresses both impairments associated with diseases and not associated with diseases, making it easier to understand the mechanisms involved. Functional Neurobiology of Aging is an important reference for professionals and students involved in aging research, as well as physicians who need to recognize and understand age-related impairments. - Organized by function, making it easy to find and understand the material - Addresses impairments both associated with diseases and not associated with diseases - Written by leading researchers in the field - Most comprehensive source of information on the neurobiology of aging
Download or read book Physical Activity and the Aging Brain written by Ronald Ross Watson and published by Academic Press. This book was released on 2016-12-15 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical Activity and the Aging Brain: Effects of Exercise on Neurological Function is a complete guide to the manifold effects of exercise and physical activity on the aging brain. Cognitive decline and motor impairment, onset of diseases and disorders, and even changes in family structure and social settings that occur as we age can all impact activity levels, yet continued physical activity is crucial for successful neurological functioning. This book examines the role that exercise and physical activity play in halting or modulating the deleterious effects of these numerous aging concerns by first examining the current state of research into how exercise manifests physical changes in the brain. It then discuss how physical activity combines with other lifestyle factors to benefit the aging brain, including nutrition, computerized brain training, and social engagement. Most significantly, it also covers how physical activity can serve as therapy to help alleviate the symptoms of various neurological diseases impacting aging populations, with particular emphasis on Alzheimer's disease and age-related cognitive decline. The book provides broad coverage of the effects of exercise and physical activity on the aging brain, its therapeutic effects, and the many factors that influence the aging process. - Presents research scientists with a complete understanding of the role of exercise in healthy brain aging - Considers the roles of nutrition, the mind-body connection, and other lifestyle factors - Presents a major resource for exercise and physical activity in the neurological health of older adults - Provides a synopsis of key ideas associated with the many aspects of physical activity, along with lifestyle factors that can modify neurological diseases and age-related neurological decline
Download or read book Aging with Grace written by David Snowdon and published by Bantam. This book was released on 2008-11-19 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1986 Dr. David Snowdon, one of the world’s leading experts on Alzheimer’s disease, embarked on a revolutionary scientific study that would forever change the way we view aging—and ultimately living. Dubbed the “Nun Study” because it involves a unique population of 678 Catholic sisters, this remarkable long-term research project has made headlines worldwide with its provocative discoveries. Yet Aging with Grace is more than a groundbreaking health and science book. It is the inspiring human story of these remarkable women—ranging in age from 74 to 106—whose dedication to serving others may help all of us live longer and healthier lives. Totally accessible, with fascinating portraits of the nuns and the scientists who study them, Aging with Grace also offers a wealth of practical findings: • Why building linguistic ability in childhood may protect against Alzheimer’s • Which ordinary foods promote longevity and healthy brain function • Why preventing strokes and depression is key to avoiding Alzheimer’s • What role heredity plays, and why it’s never too late to start an exercise program • How attitude, faith, and community can add years to our lives A prescription for hope, Aging with Grace shows that old age doesn’t have to mean an inevitable slide into illness and disability; rather it can be a time of promise and productivity, intellectual and spiritual vigor—a time of true grace.
Download or read book Future Directions for the Demography of Aging written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2018-07-21 with total page 409 pages. Available in PDF, EPUB and Kindle. Book excerpt: Almost 25 years have passed since the Demography of Aging (1994) was published by the National Research Council. Future Directions for the Demography of Aging is, in many ways, the successor to that original volume. The Division of Behavioral and Social Research at the National Institute on Aging (NIA) asked the National Academies of Sciences, Engineering, and Medicine to produce an authoritative guide to new directions in demography of aging. The papers published in this report were originally presented and discussed at a public workshop held in Washington, D.C., August 17-18, 2017. The workshop discussion made evident that major new advances had been made in the last two decades, but also that new trends and research directions have emerged that call for innovative conceptual, design, and measurement approaches. The report reviews these recent trends and also discusses future directions for research on a range of topics that are central to current research in the demography of aging. Looking back over the past two decades of demography of aging research shows remarkable advances in our understanding of the health and well-being of the older population. Equally exciting is that this report sets the stage for the next two decades of innovative researchâ€"a period of rapid growth in the older American population.
Download or read book Discovering the Brain written by National Academy of Sciences and published by National Academies Press. This book was released on 1992-01-01 with total page 195 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."
Download or read book Functional Performance in Older Adults written by Bette R Bonder and published by F.A. Davis. This book was released on 2008-10-31 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ideal resource for rehabilitation professionals who are working with or preparing to work with older adults! It describes the normal aging process, illustrates how health and social factors can impede an aging person’s abilities, and demonstrates how to develop mechanisms for maximizing the well-being of older adults.
Download or read book Aging of the Autonomic Nervous System written by Francesco Amenta and published by CRC Press. This book was released on 1993-06-16 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging of the Autonomic Nervous System is the first book devoted to the aging of the autonomic nervous system. The book presents the most recent findings on topics such as general aspects of the autonomic nervous system, main neurotransmitter systems, age-dependent changes of neuroeffector mechanisms in target organs, and therapeutic perspectives. It also provides a comprehensive analysis of the possible consequences of these findings. Aging of the Autonomic Nervous System will be a useful volume for gerontologists and neuroscientists.
Download or read book Monthly Catalog of United States Government Publications written by and published by . This book was released on 1975 with total page 2834 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Gene Therapy in Neurological Disorders written by Mingjie Li and published by Academic Press. This book was released on 2018-05-25 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene therapy has tremendous potential for the treatment of neurological disorders. There has been substantial progress in the development of gene therapy strategies for neurological disorders over the last two decades. Gene Therapy in Neurological Disorders thoroughly reviews currently available gene therapy tools and presents examples of their application in a variety of neurological diseases. The book begins with general reviews of gene therapy strategies with a focus on neurological disorders. The remainder of the chapters present approaches to specific neurological disorders. Each chapter gives an in-depth introduction to the relevant field before diving into the specific tool or application. The book aims to help investigators, students and research staff better understand the principles of gene therapy and its application in the nervous system. - Provides background information and experimental details of gene therapy tools applied for neuroscience research and neurological disorders - Covers a broad range of gene delivery and regulation tools, therapeutic agents, and target cells, including emerging new technologies such as CRISPR/Cas9 genome editing - Discusses applications of gene therapy tools to neurological disorders including neurodegeneration, muscular dystrophy, trauma and chronic pain, and neoplastic diseases
Download or read book Environmental Neurotoxicology written by National Research Council and published by National Academies Press. This book was released on 1992-02-01 with total page 167 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.
Download or read book Technology for Adaptive Aging written by National Research Council and published by National Academies Press. This book was released on 2004-04-25 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging and currently available technologies offer great promise for helping older adults, even those without serious disabilities, to live healthy, comfortable, and productive lives. What technologies offer the most potential benefit? What challenges must be overcome, what problems must be solved, for this promise to be fulfilled? How can federal agencies like the National Institute on Aging best use their resources to support the translation from laboratory findings to useful, marketable products and services? Technology for Adaptive Aging is the product of a workshop that brought together distinguished experts in aging research and in technology to discuss applications of technology to communication, education and learning, employment, health, living environments, and transportation for older adults. It includes all of the workshop papers and the report of the committee that organized the workshop. The committee report synthesizes and evaluates the points made in the workshop papers and recommends priorities for federal support of translational research in technology for older adults.
