Download or read book Innovation in Pharmacy Advances and Perspectives September 2018 written by Organizer Committee IPAP18 – Salamanca and published by Ediciones Universidad de Salamanca. This book was released on 2018-09-21 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the summaries of the "Innovation in Pharmacy: Advances and Perspectives" that took place in Salamanca (Spain) in September 2018. The early science of chemistry and microbiology were the source of most drugs until the revolution of genetic engineering in the mid 1970s. Then biotechnology made available novel protein agents such as interferons, blood factors and monoclonal antibodies that have changed the modern pharmacy. Over the past year, a new pharmacy of oligonucleotides has emerged from the science of gene expression such as RNA splicing and RNA interference. The ability to design therapeutic agents from genomic sequences will transform treatment for many diseases. The science that created this advance and its future promise will be discussed. Phillip Allen Sharp is an American geneticist and molecular biologist who co-discovered RNA splicing. He shared the 1993 Nobel Prize in Physiology or Medicine with Richard J. Roberts for “the discovery that genes in eukaryotes are not contiguous strings but contain introns, and that the splicing of messenger RNA to delete those introns can occur in different ways, yielding different proteins from the same DNA sequence. He works in Institute Professor Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, MA, US. Este libro recoge los resúmenes de la «Innovation in Pharmacy: Advances and Perspectives» que tuvo lugar en Salamanca (España) en septiembre de 2018. La ciencia primitiva de la química y la microbiología fue la fuente de la mayoría de las drogas hasta la revolución de la ingeniería genética a mediados de la década de 1970. Luego, la biotecnología puso a disposición agentes proteínicos novedosos como interferones, factores sanguíneos y anticuerpos monoclonales que han cambiado la farmacia moderna. Durante el año pasado, surgió una nueva farmacia de oligonucleótidos a partir de la ciencia de la expresión génica, como el empalme de ARN y la interferencia de ARN. La capacidad de diseñar agentes terapéuticos a partir de secuencias genómicas transformará el tratamiento de muchas enfermedades. La ciencia que creó este avance y su promesa futura será discutida. Phillip Allen Sharp es un genetista y biólogo molecular estadounidense que co-descubrió el empalme de ARN. Compartió el Premio Nobel de 1993 en Fisiología o Medicina con Richard J. Roberts por "el descubrimiento de que los genes en eucariotas no son cadenas contiguas, sino que contienen intrones, y que el empalme del ARN mensajero para eliminar esos intrones puede ocurrir de diferentes maneras, produciendo diferentes proteínas de la misma secuencia de ADN. Trabaja en el Instituto Profesor Koch Institute for Integrative Cancer Research, Instituto Tecnológico de Massachusetts (MIT), Cambridge, MA, EE. UU.

Download or read book Translational Medicine written by Joy A. Cavagnaro and published by CRC Press. This book was released on 2021-11-26 with total page 952 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.

Download or read book Developments and Advances in Defense and Security written by Álvaro Rocha and published by Springer. This book was released on 2018-04-05 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book includes a selection of articles from The 2018 Multidisciplinary International Conference of Research Applied to Defense and Security (MICRADS’18), held in Salinas, Peninsula de Santa Elena, Ecuador, from April 18 to 20, 2018. MICRADS is an international forum for researchers and practitioners to present and discuss the most recent innovations, trends, results, experiences and concerns in the various areas of defense and security, together with their technological development and applications. The main topics covered are: Information and Communication Technology in Education; Computer Vision in Military Applications; Engineering Analysis and Signal Processing; Cybersecurity and Cyberdefense; Maritime Security and Safety; Strategy, Geopolitics and Oceanopolitics; Defense planning; Leadership (e-leadership); Defense Economics; Defense Logistics; Health Informatics in Military Applications; Simulation in Military Applications; Computer Networks, Mobility and Pervasive Systems; Military Marketing; Military Physical Training; Assistive Devices and Wearable Technology; Naval and Military Engineering; Weapons and Combat Systems; Operational Oceanography. The book is aimed at all those dealing with defense and security issues, including practitioners, researchers and teachers as well as undergraduate, graduate, master’s and doctorate students.

Download or read book University and School Collaborations During a Pandemic written by Fernando M. Reimers and published by Springer Nature. This book was released on 2022 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Based on twenty case studies of universities worldwide, and on a survey administered to leaders in 101 universities, this open access book shows that, amidst the significant challenges caused by the COVID-19 pandemic, universities found ways to engage with schools to support them in sustaining educational opportunity. In doing so, they generated considerable innovation, which reinforced the integration of the research and outreach functions of the university. The evidence suggests that universities are indeed open systems, in interaction with their environment, able to discover changes that can influence them and to change in response to those changes. They are also able, in the success of their efforts to mitigate the educational impact of the pandemic, to create better futures, as the result of the innovations they can generate. This challenges the view of universities as "ivory towers" being isolated from the surrounding environment and detached from local problems. As they reached out to schools, universities not only generated clear and valuable innovations to sustain educational opportunity and to improve it, this process also contributed to transform internal university processes in ways that enhanced their own ability to deliver on the third mission of outreach

Download or read book Plant Invasions written by Giuseppe Brundu and published by . This book was released on 2001 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Fundamentals of Analytical Chemistry written by Douglas A. Skoog and published by Cengage Learning. This book was released on 2013-01-01 with total page 1152 pages. Available in PDF, EPUB and Kindle. Book excerpt: Known for its readability and systematic, rigorous approach, this fully updated FUNDAMENTALS OF ANALYTICAL CHEMISTRY, 9E, International Edition offers extensive coverage of the principles and practices of analytic chemistry and consistently shows students its applied nature. The book's award-winning authors begin each chapter with a story and photo of how analytic chemistry is applied in industry, medicine, and all the sciences. To further reinforce student learning, a wealth of dynamic photographs by renowned chemistry photographer Charlie Winters appear as chapter-openers and throughout the text. Incorporating Excel spreadsheets as a problem-solving tool, the Ninth Edition is enhanced by a chapter on Using Spreadsheets in Analytical Chemistry, updated spreadsheet summaries and problems, an "Excel Shortcut Keystrokes for the PC" insert card, and a supplement by the text authors, EXCEL® APPLICATIONS FOR ANALYTICAL CHEMISTRY, which integrates this important aspect of the study of analytical chemistry into the book's already rich pedagogy. New to this edition is OWL, an online homework and assessment tool that includes the Cengage YouBook, a fully customizable and interactive eBook, which enhances conceptual understanding through hands-on integrated multimedia interactivity.

Download or read book Hidden Hunger written by H.K. Biesalski and published by Karger Medical and Scientific Publishers. This book was released on 2016-05-24 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malnutrition caused by deficiencies of vitamins and minerals - also called hidden hunger - impairs both the intellectual and physical development of a child. Due to the absence of clinical symptoms and assessments, no intervention can be staged. The tragedy is that this, in turn, decreases the child’s chance to escape from poverty. This book looks at malnutrition in high-income countries, the nutrition transition and nutritional deficiencies in low-income countries, consequences of hidden hunger, and interventions to improve nutrition security. Written by leading experts in the field, it clearly stresses that national governments and international organizations must make malnutrition one of their top priorities in order to provide children with optimal conditions for a healthy future.

Download or read book Water and Society written by Darrell W. Pepper and published by WIT Press. This book was released on 2012 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains the papers presented at a conference co-organized by the University of Nevada-Las Vegas and the Wessex Institute of Technology to facilitate trans-disciplinary communication on issues related to the nature of water, and its use and exploitation by society. With adequate water supply becoming a critical issue in more and more area, \there is a great and urgent need to bridge the gap between the broad spectrum of social sciences and humanistic disciplines and the specialists in physical and natural sciences, biology, environmental sciences, and health. Many issues are also trans-national in nature and relate to rights of states and hence it is essential to discuss these at international level to arrive at equitable and binding solutions that will ensure the rights of society to quality water supplies. The book discusses The nature of water; Water as a human right; Water as the source of life; Water in a changing climate; Future water demands and adaptation strategies; Water resources contamination; Surface and sub-surface water resources; Irrigation and desertification; Water, sanitation and health; Transnational water rights; Legislation and controls; Water through the ages; Lessons to be learnt; and Water and disaster management.

Download or read book Cloud Computing Big Data Emerging Topics written by Marcelo Naiouf and published by Springer. This book was released on 2021-08-17 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the revised selected papers of the 9th International Conference on Cloud Computing, Big Data & Emerging Topics, JCC-BD&ET 2021, held in La Plata, Argentina*, in June 2021. The 12 full papers and 2 short papers presented were carefully reviewed and selected from a total of 37 submissions. The papers are organized in topical sections on parallel and distributed computing; machine and deep learning; big data; web and mobile computing; visualization.. *The conference was held virtually due to the COVID-19 pandemic.

Download or read book Soil and Sediment Remediation written by Piet Lens and published by IWA Publishing. This book was released on 2005-09-30 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: Soil and Sediment Remediation discusses in detail a whole set of remediative technologies currently available to minimise their impact. Technologies for the treatment of soils and sediments in-situ (landfarming, bioscreens, bioventing, nutrient injection, phytoremediation) and ex-situ (landfarming, bio-heap treatment, soil suspension reactor) will be discussed. The microbiological, process technological and socio-economical aspects of these technologies will be addressed. Special attention will be given to novel biotechnological processes that utilise sulfur cycle conversions, e.g. sulfur and heavy metal removal from soils. Also the potential of phytoremediation will be highlighted. In addition, treatment schemes for the clean-up of polluted megasites, e.g. harbours and Manufactured Gaswork Plants (MGP), will be elaborated. The aim of Soil and Sediment Remediation is to introduce the reader in: the biogeochemical characteristics of soil and sediments- new techniques to study soil/sediment processes (molecular probes, microelectrodes, NMR) clean up technologies for soils polluted with organic (PAH, NAPL, solvents) or inorganic (heavy metals) pollutants- preventative and remediative strategies and technologies available in environmental engineering novel process applications and bioreactor designs for bioremediation the impact of soil pollution on society and its economic importance.

Download or read book Investigaci n en sistemas de salud written by Instituto Nacional de Salud Pública (Mexico) and published by . This book was released on 2011 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Environmental Transport Processes written by Bruce E. Logan and published by John Wiley & Sons. This book was released on 2012-03-20 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: A unique approach to the challenges of complex environmental systems Environmental Transport Processes, Second Edition provides much-needed guidance on mass transfer principles in environmental engineering. It focuses on working with uncontrolled conditions involving biological and physical systems, offering examples from diverse fields, including mass transport, kinetics, wastewater treatment, and unit processes. This new edition is fully revised and updated, incorporating modern approaches and practice problems at the end of chapters, making the Second Edition more concise, accessible, and easy to use. The book discusses the fundamentals of transport processes occurring in natural environments, with special emphasis on working at the biological physical interface. It considers transport and kinetics in terms of systems that involve microorganisms, along with in-depth coverage of particles, size spectra, and calculations for particles that can be considered either spheres or fractals. The book's treatment of particles as fractals is especially unique and the Second Edition includes a new section on exoelectrogenic biofilms. It also addresses dispersion in natural and engineered systems unlike any other book on the subject. Readers will learn to tackle with confidence complex environmental systems and make transport calculations in heterogeneous environments with mixtures of chemicals.

Download or read book Media Activism in the Digital Age written by Victor Pickard and published by Routledge. This book was released on 2017-07-06 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Media Activism in the Digital Age captures an exciting moment in the evolution of media activism studies and offers an invaluable guide to this vibrant and evolving field of research. Victor Pickard and Guobin Yang have assembled essays by leading scholars and activists to provide case studies of feminist, technological, and political interventions during different historical periods and at local, national, and global levels. Looking at the underlying theories, histories, politics, ideologies, tactics, strategies, and aesthetics, the book takes an expansive view of media activism. It explores how varieties of activism are mediated through communication technologies, how activists deploy strategies for changing the structures of media systems, and how governments and corporations seek to police media activism. From memes to zines, hacktivism to artivism, this volume considers activist practices involving both older kinds of media and newer digital, social, and network-based forms. Media Activism in the Digital Age provides a useful cross-section of this growing field for both students and researchers.

Download or read book Geomagnetism and Aeronomy written by A. H. Waynick and published by . This book was released on 1965 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book 101 Life Skills Games for Children written by Bernie Badegruber and published by Turner Publishing Company. This book was released on 2011-01-01 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: How do you teach tolerance, self-awareness, and responsibility? How can you help children deal with fear, mistrust, or aggression? Play a game with them! Games are an ideal way to help children develop social and emotional skills; they are exciting, relaxing, and fun. 101 LIFE SKILLS GAMES FOR CHILDREN: LEARNING, GROWING, GETTING ALONG (Ages 6-12) is a resource that can help children understand and deal with problems that arise in daily interactions with other children and adults. These games help children develop social and emotional skills and enhance self-awareness. The games address the following issues: dependence, aggression, fear, resentment, disability, accusations, boasting, honesty, flexibility, patience, secrets, conscience, inhibitions, stereotypes, noise, lying, performance, closeness, weaknesses, self confidence, fun, reassurance, love, respect, integrating a new classmate, group conflict. Organized in three main chapters: (I-Games, You-Games and We-Games), the book is well structured and easily accessible. It specifies an objective for every game, gives step-by-step instructions, and offers questions for reflection. It provides possible variations for each game, examples, tips, and ideas for role plays. Each game contains references to appropriate follow-up games and is illustrated with charming drawings.

Download or read book Ontologies for Software Engineering and Software Technology written by Coral Calero and published by Springer Science & Business Media. This book was released on 2006-10-12 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers two applications of ontologies in software engineering and software technology: sharing knowledge of the problem domain and using a common terminology among all stakeholders; and filtering the knowledge when defining models and metamodels. By presenting the advanced use of ontologies in software research and software projects, this book is of benefit to software engineering researchers in both academia and industry.

Download or read book Radio Spectrum Management written by Haim Mazar (Madjar) and published by John Wiley & Sons. This book was released on 2016-08-29 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the fundamentals of wireless communications and services, explaining in detail what RF spectrum management is, why it is important, which are the authorities regulating the use of spectrum, and how is it managed and enforced at the international, regional and national levels. The book offers insights to the engineering, regulatory, economic, legal, management policy-making aspects involved. Real-world case studies are presented to depict the various approaches in different countries, and valuable lessons are drawn. The topics are addressed by engineers, advocates and economists employed by national and international spectrum regulators. The book is a tool that will allow the international regional and national regulators to better manage the RF spectrum, and will help operators and suppliers of wireless communications to better understand their regulators.