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Book Studies on Virus induced Cell Fusion  Progress Report  August 1  1977  June 30  1978

Download or read book Studies on Virus induced Cell Fusion Progress Report August 1 1977 June 30 1978 written by and published by . This book was released on 1978 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: We have previously postulated that wild-type Herpes Simplex Virus type I (HSV-1) infections are characterized by the presence of a fusion factor and a fusion inhibitor activity. The fusion inhibitor presumably is dominant so that a small fraction of cells fuse in a typical wild-type infection. Furthermore, the syn mutants isolated in our laboratory are thought to cause extensive cell fusion because the production of active fusion inhibitor in cell membranes is delayed. If mutations existed that altered both the fusion factor and fusion inhibitor activity then separate viruses containing these two mutations might be able to complement each other, each supplying the defective gene product missing in the other virus. This would produce a wild type and not a syncytial mutant response. Complementation tests between two viruses, tsB5 and syn 20, which are thought to contain defects in the production of active fusion factor and fusion inhibitor activity, respectively, were done. A wild-type response was observed indicating that the mutations affecting fusion were in two separate genes.

Book Studies on Virus induced Cell Fusion  Progress Report  July 1  1978 July 31  1979

Download or read book Studies on Virus induced Cell Fusion Progress Report July 1 1978 July 31 1979 written by and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: We have determined the extent of fusion in mixed Herpes Simplex Virus type 1 (HSV-1) cell populations. Labeled, sparse, infected cells were surrounded by unlabeled, excess, uninfected (or infected) cells to determine if fusion inhibition is active when present in the same cell as fusion factor, when present in cells that do not contain fusion factor, or in both situations. We found that wild type infected cells fuse to the same extent with each other as with uninfected cells. Therefore fusion inhibitor is active when present in the same cell as fusion factor. Other experiments indicate that the inhibition activity can also cause a small decrease of fusion when fusion factor and fusion inhibitor are present in different, but neighboring, cells. Marked variations are found in the capacity of different cell types, such as human embryonic lung (HEDL) and HEp-2 to support fusion by particular syn mutants. The difference in fusion capacity of the two cell types may be due to a difference in a cellular factor affecting the activity of viral, fusion-associated molecules, and not to cell surface differences of the uninfected cells. (PCS).

Book Nuclear Science Abstracts

Download or read book Nuclear Science Abstracts written by and published by . This book was released on 1976-04 with total page 912 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Government Reports Index

Download or read book Government Reports Index written by and published by . This book was released on 1975 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Accessions of Unlimited Distribution Reports

Download or read book Accessions of Unlimited Distribution Reports written by and published by . This book was released on 1974-07-12 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Government Reports Announcements

Download or read book Government Reports Announcements written by and published by . This book was released on 1974 with total page 1048 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Government Reports Announcements   Index

Download or read book Government Reports Announcements Index written by and published by . This book was released on 1977-02 with total page 736 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book ERDA Energy Research Abstracts

Download or read book ERDA Energy Research Abstracts written by United States. Energy Research and Development Administration and published by . This book was released on 1976 with total page 756 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Government reports annual index

Download or read book Government reports annual index written by and published by . This book was released on 199? with total page 852 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book INIS Atomindex

Download or read book INIS Atomindex written by and published by . This book was released on 1977 with total page 868 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Energy Research Abstracts

Download or read book Energy Research Abstracts written by and published by . This book was released on 1978 with total page 684 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Cumulated Index Medicus

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1974 with total page 1260 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Current Bibliography of Epidemiology

Download or read book Current Bibliography of Epidemiology written by and published by . This book was released on 1975 with total page 1408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Monthly, with annual cumulations. Comprehensive, current index to periodical medical literature intended for use of practitioners, investigators, and other workers in community medicine who are concerned with the etiology, prevention, and control of disease. Citations are derived from MEDLARS tapes for Index medicus of corresponding date. Arrangement by 2 sections, i.e., Selected subject headings, and Diseases, organisms, vaccines. No author index.

Book Bibliography of Medical Reviews

Download or read book Bibliography of Medical Reviews written by and published by . This book was released on 1971 with total page 1160 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Toxicological Profile for Lead

Download or read book Toxicological Profile for Lead written by and published by . This book was released on 2007 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Book Literature Search

    Book Details:
  • Author : National Library of Medicine (U.S.)
  • Publisher :
  • Release : 1970
  • ISBN :
  • Pages : 1848 pages

Download or read book Literature Search written by National Library of Medicine (U.S.) and published by . This book was released on 1970 with total page 1848 pages. Available in PDF, EPUB and Kindle. Book excerpt: