Download or read book Studies on the Mechanism of Action of Phorbol Esters in Skin Tumor Formation written by William McKenzie Baird and published by . This book was released on 1971 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Cellular and Biochemical Studies on the Mode of Action of the Phorbol Ester Tumor Promotors written by Kenneth Barry Delclos and published by . This book was released on 1982 with total page 472 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book TRP Channels as Therapeutic Targets written by Arpad Szallasi and published by Academic Press. This book was released on 2015-04-09 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use is authored by experts across academia and industry, providing readers with a complete picture of the therapeutic potential and challenges associated with using TRP channels as drug targets. This book offers a unique clinical approach by covering compounds that target TRP channels in pre-clinical and clinical phases, also offering a discussion of TRP channels as biomarkers. An entire section is devoted to the novel and innovative uses of these channels across a variety of diseases, offering strategies that can be used to overcome the adverse effects of first generation TRPV1 antagonists. Intended for all researchers and clinicians working toward the development of successful drugs targeting TRP channels, this book is an essential resource chocked full of the latest clinical data and findings. Contains comprehensive coverage of TRP channels as therapeutic targets, from emerging clinical indications to completed clinical trials Discusses TRP channels as validated targets, ranging from obesity and diabetes through cancer and respiratory disorders, kidney diseases, hypertension, neurodegenerative disorders, and more Provides critical analysis of the complications and side effects that have surfaced during clinical trials, offering evidence-based suggestions for overcoming them

Download or read book Naturally Occurring Phorbol Esters written by Evans and published by CRC Press. This book was released on 2018-01-18 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the topic of naturally occurring phorbol esters. Chapters include; environmental hazards of diterpene esters from plants, multi-stage carcinogenesis and the biological effects of tumor promoters, review of the family euphorbiaceae, biosynthetic and chemosystematic aspects of the euphorbiacea and thymelaeaceae, non-diterpenoid constituents of euphorbiacea, macrocyclic diterpenes of the family euphorbiacea, phorbol: its esters and derivatives, the daphnane polyol esters, the ingenane polyol esters, and the biochemical mechanism of action of phorbol ester.

Download or read book Advances in Cancer Research written by and published by Academic Press. This book was released on 1980-07-02 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Cancer Research

Download or read book Biochemistry of Smooth Muscle Contraction written by Michael Barany and published by Elsevier. This book was released on 1996-01-04 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: This valuable resource provides a systematic account of the biochemistry of smooth muscle contraction. As a comprehensive guide to this rapidly growing area of research, it covers the structure and characteristic properties of contractile and regulatory proteins, with special emphasis on their predicted function in the live muscle. Also included in this book are intermediate filament proteins, and desmin and vimentin, whose function in smooth muscle is unknown; and several enzymes involved in the phosphorylation-dephosphorylation of contractile and other proteins.

Download or read book Biomedical Index to PHS supported Research written by and published by . This book was released on 1991 with total page 1104 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book National Cancer Institute Monograph written by and published by . This book was released on 1981 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Carcinogenic and Mutagenic N substituted Aryl Compounds written by and published by . This book was released on 1982 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Research Awards Index written by and published by . This book was released on 1989 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book CRC Critical Reviews in Toxicology written by and published by . This book was released on 1972 with total page 578 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Mechanisms of Carcinogenesis written by Elizabeth K. Weisburger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: but also the possibility of intervention in specific stages. In Human behavior, including stress and other factors, plays an important role in neoplasia, although too little is known addition, variables which affect cancer development as well on the reasons for such development. Carcinogens, which as some endogenous factors can be better delineated help initiate the neoplastic process, may be either synthetic through such investigations. The topics of this volume encompass premalignant non or naturally-occurring. Cancer causation may be ascribed to invasive lesions, species-specific aspects of carcinogenicity, certain chemicals, physical agents, radioactive materials, viruses, parasites, the genetic make-up of the organism, and radiation, viruses, a quantum theory of carinogenesis, onco bacteria. Humans, eumetazoan animals and vascular plants genes, and selected environmental carcinogens. are susceptible to the first six groups of cancer causes, whe reas the last group, bacteria, seems to affect only vascular plants. Neoplastic development may begin with impairment ofJmdy defenses by a toxic material (carcinogen) which acts as an initiator, followed by promotion and progression to an overt neoplastic state. Investigation of these processes Series Editor Volume Editor allows not only a better insight into the mechanism of action Hans E. Kaiser Elizabeth K. Weisburger vii ACKNOWLEDGEMENT Inspiration and encouragement for this wide ranging project on cancer distribution and dissemination from a comparative biological and clinical point of view, was given by my late friend E. H. Krokowski.

Download or read book Journal written by National Cancer Institute (U.S.) and published by . This book was released on 1978 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Subject Index of Extramural Research Administered by the National Cancer Institute written by and published by . This book was released on 1979 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt: Current information about research grants and contracts supported by the National Cancer Institute. Subject listing gives contract or grant number and topic. Investigator, grant number, and contract number indexes.

Download or read book Journal of the National Cancer Institute written by and published by . This book was released on 2001-07 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Environmental Health Perspectives written by and published by . This book was released on 1993 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book New Molecular Targets for Cancer Chemotherapy written by David J. Kerr and published by CRC Press. This book was released on 1994-06-27 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers a wide range of novel biochemical targets that appear to be the best leads in terms of designing novel targets for anticancer drug design. New Molecular Targets for Cancer Chemotherapy is a unique, multi-disciplinary effort, with internationally respected authors from the fields of growth factor-receptor interaction, phosphoinositide and phospholipase signal transduction, and DNA-drug binding interactions. The science is placed in clinical context and illustrations explain how clinicians can incorporate a mechanistic, pharmacodynamic approach into early clinical trial design.