Download or read book Stress the Aging Brain and the Mechanisms of Neuron Death written by Robert M. Sapolsky and published by MIT Press (MA). This book was released on 1992 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: Looking beyond the now widely recognized relationships between stress and physical illness, this accessible and engagingly written book suggests that stress and stress-related hormones can also endanger the brain.
Download or read book Science and the Navy written by Harvey M. Sapolsky and published by Princeton University Press. This book was released on 2014-07-14 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addressing all those interested in the history of American science and concerned with its future, a leading scholar of public policy explains how and why the Office of Naval Research became the first federal agency to support a wide range of scientific work in universities. Harvey Sapolsky shows that the ONR functioned as a "surrogate national science foundation" between 1946 and 1950 and argues that its activities emerged not from any particularly enlightened position but largely from a bureaucratic accident. Once involved with basic research, however, the ONR challenged a Navy skeptical of the value of independent scientific advice and established a national security rationale that gave American science its Golden Age. Eventually, the ONR's autonomy was worn away in bureaucratic struggles, but Sapolsky demonstrates that its experience holds lessons for those who are committed to the effective management of science and interested in the ability of scientists to choose the directions for their research. As military support for basic research fades, scientists are discovering that they are unprotected from the vagaries of distributive politics. Originally published in 1990. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Download or read book Stress and the Aging Brain written by G. Nappi and published by Raven Press (ID). This book was released on 1990 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of the Aging Brain written by Eugenia Wang and published by Elsevier. This book was released on 1998-08-13 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of the Aging Brain brings together diverse scientific disciplines to cover the most recent research findings in an easy-to-read summary. Scientists and clinicians will find a wide spectrum of subjects including gerontology, neurology, psychology, molecular biology, and cellular biology. The book includes general chapters on the neuroanatomy and neurobiology of the aging brain, and moves on to discussion of specifics including signal transduction, cell death, and specific cellular and neurological changes associated with dementia, Alzheimer's and Parkinson's Disease. Other chapters discuss the affect of aging on learning and memory, language, and cognition.
Download or read book The Aging Mind written by National Research Council and published by National Academies Press. This book was released on 2000-04-18 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Possible new breakthroughs in understanding the aging mind that can be used to benefit older people are now emerging from research. This volume identifies the key scientific advances and the opportunities they bring. For example, science has learned that among older adults who do not suffer from Alzheimer's disease or other dementias, cognitive decline may depend less on loss of brain cells than on changes in the health of neurons and neural networks. Research on the processes that maintain neural health shows promise of revealing new ways to promote cognitive functioning in older people. Research is also showing how cognitive functioning depends on the conjunction of biology and culture. The ways older people adapt to changes in their nervous systems, and perhaps the changes themselves, are shaped by past life experiences, present living situations, changing motives, cultural expectations, and emerging technology, as well as by their physical health status and sensory-motor capabilities. Improved understanding of how physical and contextual factors interact can help explain why some cognitive functions are impaired in aging while others are spared and why cognitive capability is impaired in some older adults and spared in others. On the basis of these exciting findings, the report makes specific recommends that the U.S. government support three major new initiatives as the next steps for research.
Download or read book Stress and the Aging Brain written by Giuseppe Nappi and published by . This book was released on 1990-01-01 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Neural Plasticity and Memory written by Federico Bermudez-Rattoni and published by CRC Press. This book was released on 2007-04-17 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq
Download or read book The Aging Brain written by Lawrence J. Whalley and published by . This book was released on 2001 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt: Why do some people remain alert and vigorous at an age when others are declining mentally and physically? Does their apparent advantage have a biological basis, and, if so, could this success be transferred to others predisposed to age more quickly? If this is achievable, does brain aging then become the last obstacle to an extension of our useful life span? These are just some of the questions answered in this book by Lawrence Whalley, a researcher who specializes in the study of Alzheimer©s disease. He relates that the brain may be able to compensate for its own aging since the loss of brain cells with age is not as extensive as once believed and that, if some surviving cells retain the capacity to replicate, there may be real prospects of reducing the worst effects of brain aging. In surveying the prospects of slowing or even preventing the worst effects of aging, Whalley looks at the development of the brain and how this is influenced by environmental factors such as diet and stress, the biological and psychological mechanisms of brain injury and disease, and the range of possible treatments and preventative measures, including gene therapy, silicon-neuron implants, virtual reality, and "intelligent environments." Throughout the book he relates the known facts about brain aging, as well as our many preconceptions. Reexamining older scientific studies, the author is able to show that though much of what we take for granted about the mental processes of the older person is not simple, we may indeed be able to alleviate the effects of mental deterioration--if not now, then in the future.
Download or read book Translational Research in Traumatic Brain Injury written by Daniel Laskowitz and published by CRC Press. This book was released on 2015-12-01 with total page 412 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.
Download or read book Brain Aging written by David R. Riddle and published by CRC Press. This book was released on 2007-04-19 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur
Download or read book Magnesium in the Central Nervous System written by Robert Vink and published by University of Adelaide Press. This book was released on 2011 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Download or read book Encyclopedia of Stress written by George Fink and published by Academic Press. This book was released on 2000 with total page 793 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comprised of nearly 400 entries by leading experts on the subject, "The Encyclopedia of Stress" covers almost every aspect and ramification of stress. The book explores the effects of stress on behavior, psychiatric and psychosomatic disorders, cardiovascular systems, reproductive function, and immune function, plus stress as a consequence of work, post-traumatic stress, and stress and predisposition to disease. (Social Sciences--Psychology)
Download or read book Depression as a Systemic Illness written by James J. Strain and published by Oxford University Press. This book was released on 2018 with total page 337 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although depression has been long considered an exclusively mental disorder, this book highlights the importance of recognizing it as a systemic--physical--illness. The chapters herein present key findings from research on animal models before proceding on to examine the "allostatic" load that depression bears on the body, commonly observed patterns of depression, and illnesses that it is likely to adversely effect--through mechanisms other than that of non-compliance with treatment. The authors also explore various diagnostic dilemmas including symptom-driven, phenomenologic approaches, and discuss drug-drug interactions and the use of unique electronic health records as collaborating agents to the physician. Depression as a Systemic Illness emphasizes the need for the primary care physician to be the first agent to care for "garden variety" depressive disorders and the need to alter medical school and residency training to accommodate the development of the necessary skills, knowledge and attitudes to fulfill this goal. Its unique approach and presentation of depression makes it a key resource for clinicians within the fields of both psychiatry and primary care medicine.
Download or read book Developmental Psychopathology Volume 3 written by Dante Cicchetti and published by John Wiley & Sons. This book was released on 2006-03-31 with total page 962 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developmental Psychopathology, Volume 3, Risk, Disorder, and Adaptation provides a life span developmental perspective on "high-risk" conditions and mental disorders. Moreover, it examines developmental pathways to resilient adaptation in the face of adversity.
Download or read book Does Stress Damage the Brain written by J. Douglas Bremner and published by W. W. Norton & Company. This book was released on 2002 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: Everyone who has ever experienced stress, or wondered about the effects of stress on their minds and bodies, will benefit from the insights in this clearly written and accessible book.
Download or read book Neuronal Cell Death written by Laura Lossi and published by Humana. This book was released on 2016-08-23 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume represents a valuable and readily reproducible collection of established and emerging techniques for neuronal cell death research. Conveniently divided into four parts, sections cover a series of techniques for the molecular, structural, functional and genomic characterization of dying neurons, a number of protocols that are of primary interest in neuropathology and in experimental neuropathology, a series of gene engineering techniques to obtain and manipulate neuronal stem cells and progenitors, to prepare HSV-1 vectors for the gene therapy, and to CNS transplantation of bone marrow stem cells, and finally, some very interesting protocols for the study of cell death in non-mammalian models. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Neuronal Cell Death: Methods and Protocols seeks to serve a large audience of scientists that are currently active in the field or are willing to enter such an exciting and still expanding area of neurobiology.
Download or read book Handbook of Mental Health and Aging written by Nathan Hantke and published by Academic Press. This book was released on 2020-04-11 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Mental Health and Aging, Third Edition provides a foundational background for practitioners and researchers to understand mental health care in older adults as presented by leading experts in the field. Wherever possible, chapters integrate research into clinical practice. The book opens with conceptual factors, such as the epidemiology of mental health disorders in aging and cultural factors that impact mental health. The book transitions into neurobiological-based topics such as biomarkers, age-related structural changes in the brain, and current models of accelerated aging in mental health. Clinical topics include dementia, neuropsychology, psychotherapy, psychopharmacology, mood disorders, anxiety, schizophrenia, sleep disorders, and substance abuse. The book closes with current and future trends in geriatric mental health, including the brain functional connectome, repetitive transcranial magnetic stimulation (rTMS), technology-based interventions, and treatment innovations. Identifies factors influencing mental health in older adults Includes biological, sociological, and psychological factors Reviews epidemiology of different mental health disorders Supplies separate chapters on grief, schizophrenia, mood, anxiety, and sleep disorders Discusses biomarkers and genetics of mental health and aging Provides assessment and treatment approaches
