Download or read book Exposure Response Modeling written by Jixian Wang and published by CRC Press. This book was released on 2015-07-17 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover the Latest Statistical Approaches for Modeling Exposure-Response RelationshipsWritten by an applied statistician with extensive practical experience in drug development, Exposure-Response Modeling: Methods and Practical Implementation explores a wide range of topics in exposure-response modeling, from traditional pharmacokinetic-pharmacody

Download or read book Fundamental Statistical Inference written by Marc S. Paolella and published by John Wiley & Sons. This book was released on 2018-06-19 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: A hands-on approach to statistical inference that addresses the latest developments in this ever-growing field This clear and accessible book for beginning graduate students offers a practical and detailed approach to the field of statistical inference, providing complete derivations of results, discussions, and MATLAB programs for computation. It emphasizes details of the relevance of the material, intuition, and discussions with a view towards very modern statistical inference. In addition to classic subjects associated with mathematical statistics, topics include an intuitive presentation of the (single and double) bootstrap for confidence interval calculations, shrinkage estimation, tail (maximal moment) estimation, and a variety of methods of point estimation besides maximum likelihood, including use of characteristic functions, and indirect inference. Practical examples of all methods are given. Estimation issues associated with the discrete mixtures of normal distribution, and their solutions, are developed in detail. Much emphasis throughout is on non-Gaussian distributions, including details on working with the stable Paretian distribution and fast calculation of the noncentral Student's t. An entire chapter is dedicated to optimization, including development of Hessian-based methods, as well as heuristic/genetic algorithms that do not require continuity, with MATLAB codes provided. The book includes both theory and nontechnical discussions, along with a substantial reference to the literature, with an emphasis on alternative, more modern approaches. The recent literature on the misuse of hypothesis testing and p-values for model selection is discussed, and emphasis is given to alternative model selection methods, though hypothesis testing of distributional assumptions is covered in detail, notably for the normal distribution. Presented in three parts—Essential Concepts in Statistics; Further Fundamental Concepts in Statistics; and Additional Topics—Fundamental Statistical Inference: A Computational Approach offers comprehensive chapters on: Introducing Point and Interval Estimation; Goodness of Fit and Hypothesis Testing; Likelihood; Numerical Optimization; Methods of Point Estimation; Q-Q Plots and Distribution Testing; Unbiased Point Estimation and Bias Reduction; Analytic Interval Estimation; Inference in a Heavy-Tailed Context; The Method of Indirect Inference; and, as an appendix, A Review of Fundamental Concepts in Probability Theory, the latter to keep the book self-contained, and giving material on some advanced subjects such as saddlepoint approximations, expected shortfall in finance, calculation with the stable Paretian distribution, and convergence theorems and proofs.

Download or read book Essential Statistical Inference written by Dennis D. Boos and published by Springer Science & Business Media. This book was released on 2013-02-06 with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt: ​This book is for students and researchers who have had a first year graduate level mathematical statistics course. It covers classical likelihood, Bayesian, and permutation inference; an introduction to basic asymptotic distribution theory; and modern topics like M-estimation, the jackknife, and the bootstrap. R code is woven throughout the text, and there are a large number of examples and problems. An important goal has been to make the topics accessible to a wide audience, with little overt reliance on measure theory. A typical semester course consists of Chapters 1-6 (likelihood-based estimation and testing, Bayesian inference, basic asymptotic results) plus selections from M-estimation and related testing and resampling methodology. Dennis Boos and Len Stefanski are professors in the Department of Statistics at North Carolina State. Their research has been eclectic, often with a robustness angle, although Stefanski is also known for research concentrated on measurement error, including a co-authored book on non-linear measurement error models. In recent years the authors have jointly worked on variable selection methods. ​

Download or read book Evidential Statistics Model Identification and Science written by Mark Louis Taper and published by Frontiers Media SA. This book was released on 2022-02-15 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book The Nature of Scientific Evidence written by Mark L. Taper and published by . This book was released on 2004-10 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mark Taper, Subhash Lele and an esteemed group of contributors explore the relationships among hypotheses, models, data and interference on which scientific progress rests in an attempt to develop a new quantitative framework for evidence.

Download or read book Handbook Of Applied Econometrics And Statistical Inference written by Aman Ullah and published by CRC Press. This book was released on 2002-01-29 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summarizing developments and techniques in the field, this reference covers sample surveys, nonparametric analysis, hypothesis testing, time series analysis, Bayesian inference, and distribution theory for applications in statistics, economics, medicine, biology, engineering, sociology, psychology, and information technology. It supplies a geometric proof of an extended Gauss-Markov theorem, approaches for the design and implementation of sample surveys, advances in the theory of Neyman's smooth test, and methods for pre-test and biased estimation. It includes discussions ofsample size requirements for estimation in SUR models, innovative developments in nonparametric models, and more.

Download or read book Principles of Statistical Inference written by Luigi Pace and published by World Scientific. This book was released on 1997-08-05 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, an integrated introduction to statistical inference is provided from a frequentist likelihood-based viewpoint. Classical results are presented together with recent developments, largely built upon ideas due to R.A. Fisher. The term ?neo-Fisherian? highlights this.After a unified review of background material (statistical models, likelihood, data and model reduction, first-order asymptotics) and inference in the presence of nuisance parameters (including pseudo-likelihoods), a self-contained introduction is given to exponential families, exponential dispersion models, generalized linear models, and group families. Finally, basic results of higher-order asymptotics are introduced (index notation, asymptotic expansions for statistics and distributions, and major applications to likelihood inference).The emphasis is more on general concepts and methods than on regularity conditions. Many examples are given for specific statistical models. Each chapter is supplemented with problems and bibliographic notes. This volume can serve as a textbook in intermediate-level undergraduate and postgraduate courses in statistical inference.

Download or read book Chaos and Complexity Theory for Management Nonlinear Dynamics written by Banerjee, Santo and published by IGI Global. This book was released on 2012-11-30 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although chaos theory refers to the existence between seemingly random events, it has been gaining the attention of science, technology and managements fields. The shift from traditional procedures to the dynamics of chaos and complexity theory has resulted in a new element of complexity thinking, allowing for a greater capability for analyzing and understanding key business processes. Chaos and Complexity Theory for Management: Nonlinear Dynamics explores chaos and complexity theory and its relationship with the understanding of natural chaos in the business environment. Utilizing these theories aids in comprehending the development of businesses as a complex adaptive system.

Download or read book Probability Theory and Statistical Inference written by Aris Spanos and published by Cambridge University Press. This book was released on 2019-09-19 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt: This empirical research methods course enables informed implementation of statistical procedures, giving rise to trustworthy evidence.

Download or read book Principles Of Statistical Inference From A Neo fisherian Perspective written by Luigi Pace and published by World Scientific Publishing Company. This book was released on 1997-08-05 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, an integrated introduction to statistical inference is provided from a frequentist likelihood-based viewpoint. Classical results are presented together with recent developments, largely built upon ideas due to R.A. Fisher. The term “neo-Fisherian” highlights this.After a unified review of background material (statistical models, likelihood, data and model reduction, first-order asymptotics) and inference in the presence of nuisance parameters (including pseudo-likelihoods), a self-contained introduction is given to exponential families, exponential dispersion models, generalized linear models, and group families. Finally, basic results of higher-order asymptotics are introduced (index notation, asymptotic expansions for statistics and distributions, and major applications to likelihood inference).The emphasis is more on general concepts and methods than on regularity conditions. Many examples are given for specific statistical models. Each chapter is supplemented with problems and bibliographic notes. This volume can serve as a textbook in intermediate-level undergraduate and postgraduate courses in statistical inference.

Download or read book Lectures on Probability Theory and Mathematical Statistics 3rd Edition written by Marco Taboga and published by Createspace Independent Publishing Platform. This book was released on 2017-12-08 with total page 670 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is a collection of 80 short and self-contained lectures covering most of the topics that are usually taught in intermediate courses in probability theory and mathematical statistics. There are hundreds of examples, solved exercises and detailed derivations of important results. The step-by-step approach makes the book easy to understand and ideal for self-study. One of the main aims of the book is to be a time saver: it contains several results and proofs, especially on probability distributions, that are hard to find in standard references and are scattered here and there in more specialistic books. The topics covered by the book are as follows. PART 1 - MATHEMATICAL TOOLS: set theory, permutations, combinations, partitions, sequences and limits, review of differentiation and integration rules, the Gamma and Beta functions. PART 2 - FUNDAMENTALS OF PROBABILITY: events, probability, independence, conditional probability, Bayes' rule, random variables and random vectors, expected value, variance, covariance, correlation, covariance matrix, conditional distributions and conditional expectation, independent variables, indicator functions. PART 3 - ADDITIONAL TOPICS IN PROBABILITY THEORY: probabilistic inequalities, construction of probability distributions, transformations of probability distributions, moments and cross-moments, moment generating functions, characteristic functions. PART 4 - PROBABILITY DISTRIBUTIONS: Bernoulli, binomial, Poisson, uniform, exponential, normal, Chi-square, Gamma, Student's t, F, multinomial, multivariate normal, multivariate Student's t, Wishart. PART 5 - MORE DETAILS ABOUT THE NORMAL DISTRIBUTION: linear combinations, quadratic forms, partitions. PART 6 - ASYMPTOTIC THEORY: sequences of random vectors and random variables, pointwise convergence, almost sure convergence, convergence in probability, mean-square convergence, convergence in distribution, relations between modes of convergence, Laws of Large Numbers, Central Limit Theorems, Continuous Mapping Theorem, Slutsky's Theorem. PART 7 - FUNDAMENTALS OF STATISTICS: statistical inference, point estimation, set estimation, hypothesis testing, statistical inferences about the mean, statistical inferences about the variance.

Download or read book Error and Inference written by Deborah G. Mayo and published by Cambridge University Press. This book was released on 2009-10-26 with total page 491 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although both philosophers and scientists are interested in how to obtain reliable knowledge in the face of error, there is a gap between their perspectives that has been an obstacle to progress. By means of a series of exchanges between the editors and leaders from the philosophy of science, statistics and economics, this volume offers a cumulative introduction connecting problems of traditional philosophy of science to problems of inference in statistical and empirical modelling practice. Philosophers of science and scientific practitioners are challenged to reevaluate the assumptions of their own theories - philosophical or methodological. Practitioners may better appreciate the foundational issues around which their questions revolve and thereby become better 'applied philosophers'. Conversely, new avenues emerge for finally solving recalcitrant philosophical problems of induction, explanation and theory testing.

Download or read book Targeted Learning written by Mark J. van der Laan and published by Springer Science & Business Media. This book was released on 2011-06-17 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: The statistics profession is at a unique point in history. The need for valid statistical tools is greater than ever; data sets are massive, often measuring hundreds of thousands of measurements for a single subject. The field is ready to move towards clear objective benchmarks under which tools can be evaluated. Targeted learning allows (1) the full generalization and utilization of cross-validation as an estimator selection tool so that the subjective choices made by humans are now made by the machine, and (2) targeting the fitting of the probability distribution of the data toward the target parameter representing the scientific question of interest. This book is aimed at both statisticians and applied researchers interested in causal inference and general effect estimation for observational and experimental data. Part I is an accessible introduction to super learning and the targeted maximum likelihood estimator, including related concepts necessary to understand and apply these methods. Parts II-IX handle complex data structures and topics applied researchers will immediately recognize from their own research, including time-to-event outcomes, direct and indirect effects, positivity violations, case-control studies, censored data, longitudinal data, and genomic studies.

Download or read book Journal of the American Statistical Association written by and published by . This book was released on 2008 with total page 876 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Linear Models written by Calyampudi R. Rao and published by Springer Science & Business Media. This book was released on 2006-04-06 with total page 439 pages. Available in PDF, EPUB and Kindle. Book excerpt: An up-to-date account of the theory and applications of linear models, for use as a textbook in statistics at graduate level as well as an accompanying text for other courses in which linear models play a part. The authors present a unified theory of inference from linear models with minimal assumptions, not only through least squares theory, but also using alternative methods of estimation and testing based on convex loss functions and general estimating equations. Highlights include: - a special emphasis on sensitivity analysis and model selection; - a chapter devoted to the analysis of categorical data based on logic, loglinear, and logistic regression models; - a chapter devoted to incomplete data sets; - an extensive appendix on matrix theory; - a chapter devoted to the analysis of categorical data based on a unified presentation of generalized linear models including GEE-methods for correlated response; - a chapter devoted to incomplete data sets including regression diagnostics to identify Non-MCAR-processes The material covered is thus invaluable not only to graduates, but also to researchers and consultants in statistics.

Download or read book Handbook of Structural Equation Modeling written by Rick H. Hoyle and published by Guilford Publications. This book was released on 2023-02-17 with total page 801 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This accessible volume presents both the mechanics of structural equation modeling (SEM) and specific SEM strategies and applications. The editor, along with an international group of contributors, and editorial advisory board are leading methodologists who have organized the book to move from simpler material to more statistically complex modeling approaches. Sections cover the foundations of SEM; statistical underpinnings, from assumptions to model modifications; steps in implementation, from data preparation through writing the SEM report; and basic and advanced applications, including new and emerging topics in SEM. Each chapter provides conceptually oriented descriptions, fully explicated analyses, and engaging examples that reveal modeling possibilities for use with readers' data. Many of the chapters also include access to data and syntax files at the companion website, allowing readers to try their hands at reproducing the authors' results"--

Download or read book Linear Models in Statistics written by Alvin C. Rencher and published by John Wiley & Sons. This book was released on 2008-01-07 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: The essential introduction to the theory and application of linear models—now in a valuable new edition Since most advanced statistical tools are generalizations of the linear model, it is neces-sary to first master the linear model in order to move forward to more advanced concepts. The linear model remains the main tool of the applied statistician and is central to the training of any statistician regardless of whether the focus is applied or theoretical. This completely revised and updated new edition successfully develops the basic theory of linear models for regression, analysis of variance, analysis of covariance, and linear mixed models. Recent advances in the methodology related to linear mixed models, generalized linear models, and the Bayesian linear model are also addressed. Linear Models in Statistics, Second Edition includes full coverage of advanced topics, such as mixed and generalized linear models, Bayesian linear models, two-way models with empty cells, geometry of least squares, vector-matrix calculus, simultaneous inference, and logistic and nonlinear regression. Algebraic, geometrical, frequentist, and Bayesian approaches to both the inference of linear models and the analysis of variance are also illustrated. Through the expansion of relevant material and the inclusion of the latest technological developments in the field, this book provides readers with the theoretical foundation to correctly interpret computer software output as well as effectively use, customize, and understand linear models. This modern Second Edition features: New chapters on Bayesian linear models as well as random and mixed linear models Expanded discussion of two-way models with empty cells Additional sections on the geometry of least squares Updated coverage of simultaneous inference The book is complemented with easy-to-read proofs, real data sets, and an extensive bibliography. A thorough review of the requisite matrix algebra has been addedfor transitional purposes, and numerous theoretical and applied problems have been incorporated with selected answers provided at the end of the book. A related Web site includes additional data sets and SAS® code for all numerical examples. Linear Model in Statistics, Second Edition is a must-have book for courses in statistics, biostatistics, and mathematics at the upper-undergraduate and graduate levels. It is also an invaluable reference for researchers who need to gain a better understanding of regression and analysis of variance.