Download or read book Spider Venoms written by P. Gopalakrishnakone and published by Springer. This book was released on 2016-05-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the field of Toxinology has expanded substantially. On the one hand it studies venomous animals, plants and micro organisms in detail to understand their mode of action on targets. While on the other, it explores the biochemical composition, genomics and proteomics of toxins and venoms to understand their three interaction with life forms (especially humans), development of antidotes and exploring their pharmacological potential. Therefore, Toxinology has deep linkages with biochemistry, molecular biology, anatomy and pharmacology. In addition, there is a fast developing applied subfield, clinical toxinology, which deals with understanding and managing medical effects of toxins on human body. Given the huge impact of toxin-based deaths globally, and the potential of venom in generation of drugs for so-far incurable diseases (for example, Diabetes, Chronic Pain), the continued research and growth of the field is imminent. This has led to the growth of research in the area and the consequent scholarly output by way of publications in journals and books. Despite this ever growing body of literature within biomedical sciences, there is still no all-inclusive reference work available that collects all of the important biochemical, biomedical and clinical insights relating to Toxinology. The Handbook of Toxinology aims to address this gap and cover the field of Toxinology comprehensively.
Download or read book Snake and Spider Toxins written by Avi Priel and published by Humana. This book was released on 2020-10-02 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume explores techniques and protocols, across various biological disciplines, used to study snake and spider peptide toxins. The chapters in this book are organized into four parts and cover topics such as the use of toxins in drug development; analysis of bioactivity of complex mixtures like venom; extraction of venom glands and the production of toxins; characterization of toxins from the RNA level to the peptide structure; and the determination of the toxin’s biological function. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Snake and Spider Toxins: Methods and Protocols is a valuable resource for both novice and expert researchers who are interested in learning more about this evolving field.
Download or read book The Brown Recluse Spider written by Richard S. Vetter and published by Cornell University Press. This book was released on 2015-05-07 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brown recluse is a fascinating spider very well adapted to dwelling in houses and other buildings. Because of this very quality and the ghastly reputation associated with the medical consequences of its bite, it has become infamous throughout North America. Although recluse spiders can cause serious skin injuries and, in very rare cases, death, the danger posed by this spider is often exaggerated as a result of arachnophobia and the misdiagnosis of non-spider-related conditions as brown recluse bites. These misdiagnoses often occur in areas of North America where the spider does not exist, making legitimate bites improbable. One of the greatest factors that keeps the myths alive is misidentification of common (and harmless) spiders as brown recluses. With this book, Richard S. Vetter hopes to educate readers regarding the biology of the spider and medical aspects of its bites, to reduce the incidence of misdiagnoses, and to quell misplaced anxiety. In The Brown Recluse Spider, Vetter covers topics such as taxonomy, identification, misidentification, life history characteristics and biology, medical aspects of envenomations, medical conditions misdiagnosed as brown recluse bites, other spider species of medical consideration (several of which have been wrongly implicated as threats to human health), and the psychology behind the entrenched reasons why people believe so deeply in the presence of the spider in the face of strong, contradictory information. Vetter also makes recommendations for control of the spider for households in areas where the spiders are found and describes other species of recluse spiders in North America. Although The Brown Recluse Spider was written for a general audience, it is also a valuable source of information for arachnologists and medical personnel.
Download or read book Encyclopaedia Britannica written by Hugh Chisholm and published by . This book was released on 1910 with total page 1090 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eleventh edition was developed during the encyclopaedia's transition from a British to an American publication. Some of its articles were written by the best-known scholars of the time and it is considered to be a landmark encyclopaedia for scholarship and literary style.
Download or read book Venoms to Drugs written by Glenn F. King and published by Royal Society of Chemistry. This book was released on 2015-01-27 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: The pharmaceutical industry has become increasingly interested in biologics from animal venoms as a potential source for therapeutic agents in recent years, with a particularly emphasis on peptides. To date six drugs derived from venom peptides or proteins have been approved by the FDA, with nine further agents currently being investigated in clinical trials. In addition to these drugs in approved or advanced stages of development, many more peptides and proteins are being studied in varying stages of preclinical development. This unique book provides an up to date and comprehensive account of the potential of peptides and proteins from animal venoms as possible therapeutics. Topics covered include chemistry and structural biology of animal venoms, proteomic and transcriptomic approaches to drug discovery, bioassays, high-throughput screens and target identification, and reptile, scorpion, spider and cone snail venoms as a platform for drug development. Case studies are used to illustrate methods and successes and highlight issues surrounding administration and other important lessons that have been learnt from the development of approved therapeutics based on venoms. The first text to focus on this fascinating area and bridging an important gap, this book provides the reader with essential and current knowledge on this fast-developing area. Venoms to Drugs will find wide readership with researchers working in academia and industry working in all medicinal and pharmaceutical areas.
Download or read book Spider Man written by Jim Shooter and published by Marvel Universe. This book was released on 2007-04-04 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spider-Man becomes unraveled when his life is darkened by his shape-changing costume as well as his fashion sense.
Download or read book Venomous Animals and Their Venoms written by Wolfgang Bücherl and published by . This book was released on 1968 with total page 707 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ion Channel Factsbook written by and published by Academic Press. This book was released on 1995-11-16 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, sequence information, gene organization? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact? The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information overload. Each volume provides a catalogue of the essential properties of families of molecules. Gene organization, sequence information, physicochemical properties, and biological activity are presented using a common, easy to follow format. Taken together they compile everything you wanted to know about proteins but were too busy to look for.In a set of four inter-related volumes, The Ion Channel FactsBook provides a comprehensive framework of facts about channel molecules central to electrical signalling phenomena in living cells. The first volume is devoted to Extracellular Ligand-Gated Integral Receptor-Channel Families including those molecular complexes activated by: 5-Hydroxytryptamine, ATP, Glutamate, Acetylcholine, GABA, Glycine. - Nomenclature - Expression - Sequence analyses - Structure and function - Electrophysiology - Pharmacology - Information retrieval
Download or read book Neuroparasitology and Tropical Neurology written by Oscar H. Del Brutto and published by Elsevier Inc. Chapters. This book was released on 2013-07-03 with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cysticercosis, an infection caused by the cystic larvae of the pork tapeworm Taenia solium, is one of the most frequent parasitic infections of the human nervous system (neurocysticercosis). It is endemic in most of Latin America, the sub-Saharan Africa, and vast parts of Asia, including the Indian subcontinent. It has also been increasingly diagnosed in developed countries because of migration of people from endemic zones and exposure in travelers. The life cycle involves the development of the adult tapeworm in the human small intestine (after ingesting infected pork with cysts) and larval infection in pig tissues (after ingesting human stools containing the eggs of the tapeworm). Humans get infected by the fecal-oral route, most often from a direct contact with an asymptomatic Taenia carrier. Most common clinical presentations are seizures (particularly late-onset seizures), chronic headaches, and intracranial hypertension. However, cysticerci can locate anywhere in the human nervous system, thus potentially causing almost any neurological syndrome and making clinical diagnosis a difficult task. Neuroimaging is the main diagnostic tool, and specific serology confirms the diagnosis and helps to define the diagnosis when images are unclear. Factors such as location (extraparenchymal versus intraparenchymal), number, size and evolutive stage of the parasites determine the clinical manifestations, therapeutic approach, and prognosis. Management includes symptomatic drugs (analgesics, antiepileptic drugs, anti-inflammatory agents) and in many cases cysticidal drugs, either albendazole or praziquantel. In recent years, efforts have focused on transmission control and potential elimination in endemic regions.
Download or read book Advances in BioChirality written by C. Zucchi and published by Elsevier. This book was released on 1999-09-08 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chirality is a fundamental, persistent, but often overlooked feature of all living organisms on the molecular level as well as on the macroscopic scale. The high degree of preference for only one of two possible mirror image forms in Nature, often called biological homochirality is a puzzling, and not yet fully understood, phenomenon. This book covers biological homochirality from an interdisciplinary approach - contributions range from synthetic chemists, theoretical topologists and physicists, from palaeontologists and biologists to space scientists and representatives of the pharmaceutical and materials industries. Topics covered include - theory of biochirality, origins of biochirality, autocatalysis with amplification of chirality, macroscopic (present) biochirality, fossil records of chiral organisms - paleochirality, extraterrestrial origin of chirality, exceptions to the rule of biological homochirality, D-amino acids, chemical transfer of chirality, PV effects, and polarised radiation chemistry.
Download or read book Arthropod Venom Components and Their Potential Usage written by Katsuhiro Konno and published by MDPI. This book was released on 2020-03-25 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thousands of arthropod species, ranging from arachnids (spiders and scorpions) to hymenopterans (ants, bees, and wasps) and myriapods (centipedes), are venomous and use their venoms for both defense and predation. These venoms are invariably harmful to humans, and some may cause serious injuries, e.g., those from scorpions, spiders, and wasps. Arthropods’ venoms are also known as rich sources of biologically active compounds and have attracted the attention of toxin researchers for years. In this century, venom component analysis has progressed considerable due to the advances in analytical techniques, in particular, mass spectrometry and next-generation deep (DNA and RNA) sequencing. As such, proteomic and peptidomic analyses using LC–MS have enabled the full analysis of venom components, revealing a variety of novel peptide and protein toxins sequences and scaffolds, potentially useful as pharmacological research tools and for the development of highly selective peptide ligands and therapeutic leads, like chlorotoxin. Due to their specificity for numerous ion-channel subtypes, including voltage- and ligand-gated ion channels, arthropod neurotoxins have been investigated to dissect and treat neurodegenerative diseases and control epileptic syndromes. This Special Issue collects information on such progress, encouraging contributions on the chemical and biological characterization of venom components, not only peptides and proteins, but also small molecules, their mechanisms of action, and the development of venom-derived peptide leads.
Download or read book Venom s Wrath written by Keith R. A. DeCandido and published by Berkley. This book was released on 1998 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Venom is loose on the streets of New York, and only the amazing Spider-Man can stop his latest rampage! When lawyer Ann Weying--Venom's ex-wife--is snatched from her apartment by a group of radical terrorists, Spider-Man knows it's only a matter of time before Venom becomes involved in the city-wide search. But if Venom finds the kidnappers first, he's likely to eviscerate the kidnappers and cause his ex-wife to be executed at the same time! Spider-Man must find out why Ann and Daily Bugle editor-in-chief Joe Robertson have been kidnapped--and what the real motives of the terrorists might be. Racing against time, Spider-Man must keep New York from becoming the victim of Venom's wrath."--Back cover
Download or read book Handbook of Clinical Toxicology of Animal Venoms and Poisons written by Julian White and published by CRC Press. This book was released on 1995-08-22 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Clinical Toxicology of Animal Venoms is the first concise, one-volume book devoted to this important subject. The editors are internationally recognized authorities in the biology and clinical aspects of venomous and poisonous animals, and the chapter authors are world leaders in their respective fields of toxicology. All aspects of the topic are covered including information on the biology and taxonomy of poisonous animals, their venom or poison, diagnosis, and general treatment principles and specific treatment. The most up-to-date list of available antivenoms is provided. Coverage of venomous and poisonous animals is comprehensive, with thorough discussions on shellfish poisoning, ciguatera, fugu, coelenterates, stingrays, venous fish, blue-ringed octopus, sea-snakes, scorpions, spiders, insects, and gila lizards. Individual chapters focus on snakes and snakebite in Europe, Africa, Asia, Australia, North America, Central America, and South America. Nearly all clinical chapters have been written by clinicians with extensive experience treating the particular type of animal envenoming or poisoning under consideration. No other book brings together such a wealth of information in this field, and no other book provides it in a format useful to clinicians charged with the responsibility of treating envenomed or poisoned patients. The Handbook of Clinical Toxicology of Animal Venoms is an essential addition to all medical libraries, emergency departments, toxicology departments, poison information centers, and invaluable to all professionals working in these fields.
Download or read book Snakebite Spiderbite written by Julian White and published by . This book was released on 2006 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ecophysiology of Spiders written by Wolfgang Nentwig and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recently another book on insect physiology was published. It was restricted to a few focal points as are many of these new insect physiology books, but there was considerable depth in its specialized point of view. We were dis cussing the structure of this book and of insect physiology books, in general, when Prof. Remmert asked me " . . . and what about books on spider physio logy?" Silence. Then I started to explain "oh yes, there is a congress pro ceedings volume on this topic and there is a group with excellent publica tions on another topic . . . ", but I felt that this answer was weak. One can no longer buy the proceedings volume in a bookshop and to read a series of publications on a given topic one must search in a library for a dozen journals. Why is there not a single book on spider physiology comparable with the many books on insect physiology? Are spiders a scientific ivory tower, far from public interest and commercial importance? I do not think so, although spiders are one of the many "forgotten" animal groups which always grew in the shadow of the insects. There are research groups working on spider physiology, there are fascinating phenomena in this animal group and there are plenty of exciting results. Spiders may have been always underresearch ed, but research is progressing. In the last few years, new books have been published, e. g.
Download or read book Venom s Taste written by Lisa Smedman and published by Wizards of the Coast. This book was released on 2010-04-21 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: New York Times–bestselling author: When an evil cult forms an alliance with Sybil’s Chosen, the humans of Hlondeth face horrors unlike any other Enter the mysterious world of Hlondeth, a city populated by the humanoid serpents known as the yuan-ti, and ruled by House Extaminos. This powerful House of Serpents is the ultimate target of The Pox, a human cult whose members worship the goddess of plague and disease. Not only that, but they have begun to work the deadly will of Sybil’s Chosen, a dangerous cabal of yuan-ti who will turn Hlondeth citizens into freakish ‘tainted ones’. Amid this chaos is a human psionic named Arvin, who suddenly finds himself embroiled in schemes far beyond his understanding. His recruitment to the local thieves guild sends him down a twisted path of danger and corruption, bringing him face to face with the dreaded Pox and the true nature of his psionic powers. Elsewhere, hope emerges in the form of a yuan-ti half-blood, Dediana—the only one who can stop Sibyl and her puppet organization from turning all humans into the slaves of heartless, serpentine masters.
Download or read book Venom written by David Michelinie and published by Marvel Entertainment. This book was released on 2017-11-15 with total page 445 pages. Available in PDF, EPUB and Kindle. Book excerpt: Collecting Venom: Carnage Unleashed #1-4, Venom: Sinner Takes All #1-5; and material from Amazing Spider-Man Super Special, Spider-Man Super Special, Venom Super Special, Spectacular Spider-Man Super Special and Web of Spider-Man Super Special. Venom stars in tales of violence and vengeance! When the video game "Carnage Unleashed" becomes a hit, it provides the psychopathic Cletus Kasady with the opportunity to gain his freedom -and renew his sadistic reign of terror on the streets! The only way to stop a bad symbiote? A good(ish) symbiote! Blood will flow as Venom takes on Carnage! Then, when killer vigilante Sin-Eater strikes, Eddie Brock's ex-wife is caught in the crossfire. To survive, must she become the bride of Venom? Plus, Spider-Man and the Scarlet Spider must stand by Eddie's side when an alien invasion threatens to turn Earth into the Planet of the Symbiotes!
