Download or read book Special report on environmental endocrine disruption an effects assessment and analysis prepared for the Risk Assessment Forum U S Environmental Protection Agency written by and published by DIANE Publishing. This book was released on 1997 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book SPECIAL REPORT ON ENVIRONMENTAL ENDOCRINE DISRUPTION AN EFFECTS ASSESSMENT AND ANALYSIS U S ENVIRONMENTAL PROTECTION AGENCY FEBRUAR written by and published by . This book was released on 1998* with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Special Report on Environmental Endocrine Disruption an Effects Assessment and Analysis written by Environmental Protection Agency EPA : Office of Research and Development and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Special Report on Environmental Endocrine Disruption written by Thomas M. Crisp and published by . This book was released on 1997 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Review of the Environmental Protection Agency s State of the Science Evaluation of Nonmonotonic Dose Response Relationships as they Apply to Endocrine Disruptors written by National Research Council and published by National Academies Press. This book was released on 2014-05-27 with total page 89 pages. Available in PDF, EPUB and Kindle. Book excerpt: Potential health effects from chemicals that disrupt endocrine function pose an environmental health concern because of their ability to interfere with normal hormone function in human and wildlife populations. The endocrine system regulates biological processes throughout the body and is sensitive to small changes in hormone concentrations. Endocrine-disruptor research has focused primarily on chemicals that affect three hormone pathways that play important roles in reproduction and development - the estrogen, androgen, and thyroid hormone pathways. Some of this research has identified dose-response relationships that have nonmonotonic curves. Nonmonotonic dose-response curves (NMDRs) are of concern because they do not follow the usual assumption made in toxicology that as dose decreases the response also decreases. The existence of NMDRs has been a controversial topic for decades, and there has been considerable debate about their implications for how chemicals are tested and for how risks from such chemicals are assessed. Toxicity tests are designed to identify hazards and to characterize dose-response relationships, so tests are aimed at finding a (high) dose that elicits a response, and dose-response is explored by testing lower doses spaced to identify statistically a no- or lowest-observed-adverse-effect level. The concern for NMDRs is that such studies, as currently designed, might not detect the inflection of the dose-response curve if only a few doses are tested or if the change in inflection occurs below the range of doses tested. Another concern is that some NMDRs are found for biological effects that are not usually evaluated in toxicity tests. If current testing strategies are inadequate to account for NMDRs, changes to risk assessment practices might be necessary. To help address these issues, the U.S. Environmental Protection Agency (EPA) developed a draft State-of-the-Science Evaluation: Nonmonotonic Dose Responses as they Apply to Estrogen, Androgen, and Thyroid Pathways and EPA Testing and Assessment Procedures. EPA asked the National Research Council to conduct an independent review of this evaluation to ensure that it is scientifically sound and of high quality. Review of Environmental Protection Agency's State-of-the-Science Evaluation of Nonmonotonic Dose-Response as they Apply to Endocrine Disrupters evaluates whether EPA's evaluation presents a scientifically sound and high-quality analysis of the literature on NMDRs. This report reviews how well the EPA evaluation described how the assessment was performed, whether consistent methods and criteria were applied in the analysis of different evidence streams, and whether appropriate methods were applied to evaluating the evidence. The report makes recommendations to improve EPA's process and strengthen the evaluation.
Download or read book EPA Special Report On Endocrine Disruption written by and published by . This book was released on 1997 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Endocrine Issues Update written by AJ. Duggan and published by . This book was released on 1998 with total page 14 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is growing controversy that low-level exposures to chemicals and pesticides have caused increased incidences of reproductive system cancers, developmental abnormalities and physical deformities in wildlife and humans. Substances that cause these effects are called endocrine disrupters. The science to address endocrine issues is still developing, but poignant publications, such as Theo Colborn's Our Stolen Future, have fueled the controversy and increased public awareness about endocrine issues. EPA recently issued the "Special Report on Endocrine Disruption: An Effects Assessment and Analysis Document." The report concluded that environmental contaminants can adversely affect animals and wildlife, but more research is warranted to determine the causal relationship between exposure and adverse health effects in humans. In August 1996, Congress enacted legislation that directed EPA to implement, by August 1999, a screening and testing program to evaluate chemicals and pesticides for endocrine effects. In October 1996, EPA convened a Federal Advisory Committee, EDSTAC (Endocrine Disrupter Screening and Testing Advisory Committee), of stakeholders and scientists from various activist groups, government and industry to assist them in the process.
Download or read book Endocrine Disruptors written by Ahmed R. G. and published by BoD – Books on Demand. This book was released on 2018-10-10 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: The World Health Organization estimated that each year there are more than 13 million deaths caused by environmental causes. Exposure to endocrine disrupting chemicals (EDCs) during development may cause long-term health outcomes. This book, Endocrine Disruptors, includes eight chapters that illustrate potential endocrine-disrupting activities in water, sediments, crops, animals, and humans. This book assesses the relationship between the EDCs and development, reproduction, or obesity. Finally, detection of the levels of EDCs by autobioluminescent cellular bioreporters is discussed. Scientists, physicians, neuroendocrinologists, neurotoxicologists, and lay readers who have engaged in EDC studies or practice will discover that this book offers insight into all areas of EDC research.
Download or read book Analysis of Endocrine Disrupting Compounds in Food written by Leo M. L. Nollet and published by John Wiley & Sons. This book was released on 2011-06-09 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Analysis of Endocrine Disrupting Compounds in Food provides a unique and comprehensive professional reference source covering most of the recent analytical methodology of endocrine disrupting compounds in food. Editor Nollet and his broad team of international contributors address the most recent advances in analysis of endocrine disrupting chemicals in food. While covering conventional (typically lab-based) methods of analysis, the book focuses on leading-edge technologies that recently have been introduced. The book looks at areas such as food quality assurance and safety. Issues such as persistent organic pollutants, monitoring pesticide and herbicide residues in food, determining heavy and other metals in food and discussing the impacts of dioxins, PCBs, PCDFs and many other suspected chemicals are covered. The book discusses the relationship between chemical compounds and hormone activity. What are the health impacts of different chemical compounds for men and animals? How are these compounds entering in foodstuffs? Analysis of Endocrine Disrupting Compounds in Food offers the food professional what its title promises – a compendium of sample preparation and analysis techniques of possible endocrine disrupting compounds in food. Special Features: Uniquely concentrates on analysis and detection methods of EDCs in foodstuffs Extensive coverage of the main types of globally available analytical techniques and methodologies Fully detailed properties, sample procedures, and analysis steps for each EDC Renowned editor Leo Nollet leads a broad team of international experts
Download or read book Analysis of Environmental Endocrine Disruptors written by Larry L. Needham and published by . This book was released on 2000 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annotation Endocrine disruptors are chemical compounds that can be found in common products and cause birth defects in humans and animals and other harm. This book looks at recent developments in the area and examines screening/monitoring methods and analytical techniques.
Download or read book Environmentally Induced Illnesses written by Thomas Kerns and published by McFarland. This book was released on 2012-07-24 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Readers drawn to Rachel Carson's Silent Spring, Laurie Garrett's The Coming Plague, or Theo Colburn's Our Stolen Future will appreciate this work by Thomas Kerns as well. The growing epidemics of chemically induced illnesses from long-term, low-dose exposure to toxicants in both developed and developing nations are being studied by serious researchers. Questions are being raised as to how societies will deal with these new problems. Kerns's book is the first to directly address the ethical dimension of managing environmental health and ubiquitous toxicants (such as solvents, pesticides, and artificial fragrances). The work includes recent medical literature on chronic health effects from exposure to toxicants and the social costs of these disorders; relevant historic and human rights documents; recommendations for public policy and legislation; and primary obstacles faced by public health advocates. College instructors and students, victims of chemical sensitivity disorders, public health workers, scientists, and policymakers who are interested in the challenge of these emerging epidemics will find Kerns's text highly informative.
Download or read book Toxicological profile for benzene written by and published by . This book was released on 2007 with total page 444 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Toxicological Profile for Selenium Update written by John Risher and published by DIANE Publishing. This book was released on 2011-05 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Selenium (SE) and its compounds are used in photographic devices, gun gluing, plastics, paints, anti-dandruff shampoos, vitamin and mineral supp., fungicides, and glass. It is also used to prepare drugs and as a nutritional feed supp. for poultry and livestock. This profile includes: (a) The exam¿n. of toxicologic info. and epidemiologic evaluations on SE to ascertain the levels of significant human exposure for the substance and the chronic health effects; (b) A determination of whether adequate info. on the health effects of SE is avail. to determine levels of exposure that present a significant risk to human health (SRHH); and (c) Ident¿n. of toxicologic testing needed to identify the types of exposure that may present SRHH. Illus. A print on demand pub.
Download or read book Proceedings of the 1997 Great Lakes Endocrine Disrupters Symposium written by and published by . This book was released on 1997 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book EPA Publications Bibliography written by United States. Environmental Protection Agency and published by . This book was released on 1997 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Environmental Health Perspectives written by and published by . This book was released on 2000 with total page 1724 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Water resources Investigations Report written by and published by . This book was released on 2000 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt:
