Download or read book Somites in Developing Embryos written by Ruth Bellairs and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Somite development is a unique and important topic; unique because somitic mesoderm is the first tissue to become segmented, important because the somites - once established - exert a profound influence on other seg mental structures which form later. Somite development is of interest at a number of levels. In one aspect, demarcation of a specific number of somites and size regulation, it is a particularly intriguing example of embryonic pattern formation, 'especially in vew of its possible relation to homoeobox-controlled segmentation in insects. At another level, somite development has long been studied by compara tive anatomists, but only recently has new light been thrown on such sub jects as segmentation of the head, proposed in the 18th century by Goethe and now a live issue for developmental biologists. Somit es are simple when they first appear, but very complex structures arise from them. These include the vertebrae and the axial and other muscles and consequently there is a wealth of morphogenetic problems to be explored. Sometimes their morphogenesis is disturbed, by genetic or environ mental factors, and there are many clinical conditions which arise as a result.

Download or read book Somitogenesis Part 1 written by and published by Academic Press. This book was released on 1999-12-06 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: The chapters contained in this two-volume set provide a broad perspective on the novel strategies and conceptual paradigms that drive the current resurgence of interest in somitogenesis - the process by which somites form and elaborate differentiated tissues and structures. Because somites are a ubiquitous feature of vertebrate embryos, they can be studied in a variety of experimental animal models including those amenable to genetic (zebrafish, mammalian), molecular/genetic (mammalian, avian) as well as those already well established for classical experimental embryological and cell biological studies (amphibians, avian). The wide variety of experimental approaches to somitogenesis that are presented in these volumes will leave the reader with a broad perspective on how current research in somitogenesis is helping to solve fundamental questions in vertebrate development and morphogenesis.Key Features:* Novel transcriptional mechanisms that control repetitive pattern formation* Wide scale genetic screens for mutations affecting somitogenesis* Molecular/genetic control of pattern and tissue formation during somitogenesis* Transplantation of mouse embryo somites* Classical embryological approaches and concepts* Evolutionary perspectives on somitogenesis

Download or read book Models of Biological Pattern Formation written by Hans Meinhardt and published by . This book was released on 1982 with total page 252 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Mathematical Biology And Biological Physics written by Rubem P Mondaini and published by #N/A. This book was released on 2017-07-14 with total page 381 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a book on interdisciplinary topics of the Mathematical and Biological Sciences. The treatment is both pedagogical and advanced in order to motivate research students as well as to fulfill the requirements of professional practitioners. There are comprehensive reviews written by senior experts on the important problems of growth and agglomeration in biology, on the algebraic modelling of the genetic code and on multi-step biochemical pathways.There are new results on the state of the art research in the pattern recognition of probability distribution of amino acids, on somitogenesis through reaction-diffusion models, on the mathematical modelling of infectious diseases, on the biophysical modelling of physiological disorders, on the sensitive analysis of parameters of malaria models, on the stability and hopf bifurcation of ecological and epidemiological models, on the viral infection of bee colonies and on the structure and motion of proteins. All these contributions are also strongly recommended to professionals from other scientific areas aiming to work on these interdisciplinary fields.

Download or read book Building the Most Complex Structure on Earth written by Nelson R Cabej and published by Newnes. This book was released on 2013-04-01 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Building the Most Complex Structure on Earth provides readers with a basic biological education an easy and understandable introduction into a new epigenetic theory of development and evolution. This is a novel theory that describes the epigenetic mechanisms of the development and evolution of animals and explains the colossal evolution and diversification of animals from a new post-genetic perspective. Modern biology has demonstrated the existence of a common genetic toolkit in the animal kingdom, but neither the number of genes nor the evolution of new genes is responsible for the development and evolution of animals. The failure to understand how the same genetic toolkit is used to produce millions of widely different animal forms remains a perplexing conundrum in modern biology. The novel theory shows that the development and evolution of the animal kingdom are functions of epigenetic mechanisms, which are the competent users of the genetic toolkit. - Provides a comprehensive view of the epigenetic aspects of reproduction, development, and evolution. - Highly rigorous, but simple enough for readers with only a basic knowledge of biology.

Download or read book Mouse Development written by Janet Rossant and published by Gulf Professional Publishing. This book was released on 2002-03 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book represents a classic compilation of current knowledge about mouse development and its correlates to research in cell biology, molecular biology, genetics, and neuroscience. Emphasis is placed on the research strategy, experimental design, and critical analysis of the data, disguishing this from other books that only focus on protocols for mouse developmental research. Selected chapters are indexed to electronic databases such as GeneBank, GenBank, Electronic Mouse Atlas, and Transgenic/Knockout, further increasing the utility of this book as a reference. *Broad-based overview of mouse development from fundamental to specialist levels *Extensive coverage of a wide range of developmental mutations of the mouse *Excellent benchmark illustrations of brain, craniofacial, gut and heart development *In-depth experiment-based assessment of concepts in mammalian development *Focus on models of specific relevance to human development *Comprehensive reference to key literature and electronic databases related to mouse development *High-quality full-color production

Download or read book Principles of Developmental Genetics written by Sally A. Moody and published by Elsevier. This book was released on 2007-07-19 with total page 1094 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unlike anything currently available in the market, Dr. Sally A. Moody and a team of world-renowned experts provide a groundbreaking view of developmental genetics that will influence scientific approaches in embryology, comparative biology, as well as the newly emerging fields of stem cell biology and regenerative medicine. Principles of Developmental Genetics highlights the intersection of developmental biology with new revolutionary genomic technologies, and details how these advances have accelerated our understanding of the molecular genetic processes that regulates development. This definitive resource provides researchers with the opportunity to gain important insights into the clinical applicability of emerging new technologies and animal model data. This book is a must-have for all researchers in genetics, developmental biology, regenerative medicine, and stem cell biology.• Includes new research not previously published in any other book on the molecular geneticprocesses that regulates development• Chapters present a broad understanding on the application of animal model systems, allowingresearchers to better treat clinical disorders and comprehend human development• Relates the application of new technologies to the manipulation of stem cells, causes ofhuman birth defects, and several human disease conditions• Each chapter includes a bulleted summary highlighting clinical aspects of animal models

Download or read book Congenital Scoliosis written by Elio Ascani and published by . This book was released on 1988 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third volume of Progress in Spinal Pathology gathers a selection of papers presented at the 7th National Meeting of the Italian Scoliosis Research Group on Congenital Scoliosis. Up until 20 years ago congenital scoliosis was considered to be a practically benign disease characterized by a slight progression of spinal deformity and its prognosis was consequently good. This statement has recently turned out to be too optimistic. Deeper studies on spinal pathology have proved the existence of highly progressive forms of congenital scoliosis often associated with other diseases affecting the urinary and cardiac systems and above all the spinal cord. As a result a careful evaluation of the patient is necessary before any type of surgical treatment may be initiated, in order to reduce the risk of irreversible lesions to the spinal cord to a minimum. This volume encompasses all clinical and diagnostic aspects of the subject including the latest achievements and techniques of treatment. Furthermore it is completed by eminent studies on subjects of great interest such as imperfect osteogenesis, cervical and cranial abnormalities in von Recklinghausen's disease, experimental comparative analysis of different types of instrumentation used in the surgical treatment of vertebral fractures, rib resection following vertebral arthrodesis for cases of thoracic idiopathic scoliosis, and anesthesia in vertebral surgery for spinal muscle atrophy.

Download or read book Handbook of Marine Model Organisms in Experimental Biology written by Agnes Boutet and published by CRC Press. This book was released on 2021-12-13 with total page 964 pages. Available in PDF, EPUB and Kindle. Book excerpt: The importance of molecular approaches for comparative biology and the rapid development of new molecular tools is unprecedented. The extraordinary molecular progress belies the need for understanding the development and basic biology of whole organisms. Vigorous international efforts to train the next-generation of experimental biologists must combine both levels – next generation molecular approaches and traditional organismal biology. This book provides cutting-edge chapters regarding the growing list of marine model organisms. Access to and practical advice on these model organisms have become a conditio sine qua non for a modern education of advanced undergraduate students, graduate students and postdocs working on marine model systems. Model organisms are not only tools they are also bridges between fields – from behavior, development and physiology to functional genomics. Key Features Offers deep insights into cutting-edge model system science Provides in-depth overviews of all prominent marine model organisms Illustrates challenging experimental approaches to model system research Serves as a reference book also for next-generation functional genomics applications Fills an urgent need for students Related Titles Jarret, R. L. & K. McCluskey, eds. The Biological Resources of Model Organisms (ISBN 978-1-1382-9461-5) Kim, S.-K. Healthcare Using Marine Organisms (ISBN 978-1-1382-9538-4) Mudher, A. & T. Newman, eds. Drosophila: A Toolbox for the Study of Neurodegenerative Disease (ISBN 978-0-4154-1185-1) Green, S. L. The Laboratory Xenopus sp. (ISBN 978-1-4200-9109-0)

Download or read book The Neural Crest written by Nicole Le Douarin and published by Cambridge University Press. This book was released on 1999-11-28 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: This 1999 edition of The Neural Crest contains comprehensive information about the neural crest, a structure unique to the vertebrate embryo, which has only a transient existence in early embryonic life. The ontogeny of the neural crest embodies the most important issues in developmental biology, as the neural crest is considered to have played a crucial role in evolution of the vertebrate phylum. Data that analyse neural crest ontogeny in murine and zebrafish embryos have been included in this revision. This revised edition also takes advantage of recent advances in our understanding of markers of neural crest cell subpopulations, and a full chapter is now devoted to cell lineage analysis. The major research breakthrough since the first edition has been the introduction of molecular biology to neural crest research, enabling an elucidation of many molecular mechanisms of neural crest development. This book is essential reading for students and researchers in developmental biology, cell biology, and neuroscience.

Download or read book Across the Bridge written by Henry Gee and published by University of Chicago Press. This book was released on 2018-07-04 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Addresses an important topic for biologists and zoologists about vertebrates’ place in the ‘grand scheme’ . . . genuinely witty and charming . . . magnificent.” —Neil J. Gostling, University of Southampton Our understanding of vertebrate origins and the backbone of human history evolves with each new fossil find and DNA map. Many species have now had their genomes sequenced, and molecular techniques allow genetic inspection of even non-model organisms. But as longtime Nature editor Henry Gee argues in Across the Bridge, despite these giant strides and our deepening understanding of how vertebrates fit into the tree of life, the morphological chasm between vertebrates and invertebrates remains vast and enigmatic. As Gee shows, even as scientific advances have falsified a variety of theories linking these groups, the extant relatives of vertebrates are too few for effective genetic analysis. Moreover, the more we learn about the species that do remain—from sea-squirts to starfish—the clearer it becomes that they are too far evolved along their own courses to be of much use in reconstructing what the latest invertebrate ancestors of vertebrates looked like. Fossils present yet further problems of interpretation. Tracing both the fast-changing science that has helped illuminate the intricacies of vertebrate evolution as well as the limits of that science, Across the Bridge helps us to see how far the field has come in crossing the invertebrate-to-vertebrate divide—and how far we still have to go. “A beautiful ode to some of the least appreciated animals . . . guides the reader joyfully through deuterostomes—weaving disparate elements of embryology, paleontology, and morphology into an unprecedented and accessible narrative.” —Jakob Vinther, University of Bristol

Download or read book Organogenesis of the Kidney written by Lauri Saxen and published by Cambridge University Press. This book was released on 1987-04-16 with total page 185 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although this description of a model system for cell differentation and organogenesis emphasizes the mammalian kidney, detailed coverage is also given to the development of the transient excretory organs.

Download or read book Fetal Therapy written by Mark D. Kilby and published by Cambridge University Press. This book was released on 2013 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers the latest insights any fetal specialist needs and provides essential knowledge for professionals caring for women with high-risk pregnancies.

Download or read book The Zebrafish in Biomedical Research written by Samuel Cartner and published by Academic Press. This book was released on 2019-11-22 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provides significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using the species to gain critical insights into human physiology and disease. As the zebrafish has become an important model organism for the study of vertebrate development and disease, organ function, behavior, toxicology, cancer, and drug discovery, this book presents an important resource for future research. - Presents a complete view of the zebrafish, covering their biology, husbandry, diseases and research applications - Includes the work of world-renowned authors - Provides the first authoritative and comprehensive treatment of zebrafish in biomedical research as part of the ACLAM series

Download or read book The Dynamic Architecture of a Developing Organism written by L.V. Beloussov and published by Springer Science & Business Media. This book was released on 2013-04-18 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: For anybody capable of an emotional response to it, any view of a developing organism should give birth to a feeling of amazement and even admiration, whether this development is seen directly, or in the form of a time lapse film, or even if mentally reconstructed from a series of static images. We ask ourselves how such seemingly primitive eggs or pieces of tissue, without any obvious intervention from outside, so regularly transform themselves into precisely constructed adult organisms. If we try to formulate what amazes us most of all about development, the answer will probably be that it is the internal capacity of developing organisms themselves to create new structures. How, then, can we satisfy our amazement in ways that are more or less reasonable, as well as scientifically valuable? This depends, first of all, on what position we choose to regard embryonic development as occupying among other structure creating processes, even including human activities. On the one hand, one might regard the development of organisms as a highly specialized class of processes, unique to themselves and alien to the general laws of nature, or at least not derivable from them and more akin to the deliberate acts of our own human behaviour. In that case our task would become reduced to a search for some specific 'instructions' for each next member of such a class. Whether in an overt or hidden form, some such ideology seems to dominate in present day developmental biology.

Download or read book Epigenetic Principles of Evolution written by Nelson R Cabej and published by Elsevier. This book was released on 2011-11-22 with total page 847 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first and only book, so far, to deal with the causal basis of evolution from an epigenetic view. By revealing the epigenetic "user" of the "genetic toolkit", this book demonstrates the primacy of epigenetic mechanisms and epigenetic information in generating evolutionary novelties. The author convincingly supports his theory with a host of examples from the most varied fields of biology, by emphasizing changes in developmental pathways as the basic source of evolutionary change in metazoans. - Original and thought provoking--a radically new theory that overcomes the present difficulties of the theory of evolution - Is the first and only theory that uses epigenetic mechanisms and principles for explaining evolution of metazoans - Takes an integrative approach and shows a wide range of learning

Download or read book The Zebrafish Disease Models and Chemical Screens written by and published by Academic Press. This book was released on 2011-09-09 with total page 591 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Methods in Cell Biology is the 3e, and provides comprehensive compendia of laboratory protocols and reviews covering all the new methods developed since 2004. This new volume on Disease Models and Chemical Screens, covers two rapidly emerging and compelling applications of the zebrafish. - Details state-of-the art zebrafish protocols, delineating critical steps in the procedures as well as potential pitfalls - This volume concentrates on Disease Models and Chemical Screens