Download or read book Stochastic Models for Carcinogenesis written by Wai-Yuan Tan and published by CRC Press. This book was released on 2020-01-31 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: An up-to-date survey of mathematical models of carcinogenesis, providing the most recent findings of cancer biology as evidence of the models, as well as extensive bibliographies of cancer biology and in-depth mathematical analyses for each of the models. May be used as a reference for biostaticians, biometricians, mathematical and molecular biologists, applied mathematicians, oncologists, cancer and toxicology researchers, environmental scientists, and graduate students in these fields.
Download or read book written by Jean-Christophe Rufin and published by W. W. Norton & Company. This book was released on 2002-08-01 with total page 1092 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sequel to The Abyssinian finds Jean-Baptiste Poncet in Persia practicing medicine for the Shah and trying to rescue his wife and daughter from inside the walls of a city under attack. Reprint. 11,500 first printing.
Download or read book Stochastic Analysis of Carcinogenicity Experiments written by Ying Lu and published by . This book was released on 1990 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Environmental Health Perspectives written by and published by . This book was released on 1996 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Design and Analysis of Animal Studies in Pharmaceutical Development written by Shein-Chung Chow and published by CRC Press. This book was released on 1998-01-15 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Provides well-integrated, comprehensive coverage of all the major statistical designs and methods used for animal studies in pharmaceutical research and development. Demonstrates the correct way to interpret the results of animal studies in the risk assessment of biopharmaceutical products and clarifies detailed presentations with real-world examp
Download or read book Dissertation Abstracts International written by and published by . This book was released on 1999 with total page 856 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Quantitative Medical Data Analysis Using Mathematical Tools And Statistical Techniques written by Don Hong and published by World Scientific. This book was released on 2007-07-10 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative biomedical data analysis is a fast-growing interdisciplinary area of applied and computational mathematics, statistics, computer science, and biomedical science, leading to new fields such as bioinformatics, biomathematics, and biostatistics. In addition to traditional statistical techniques and mathematical models using differential equations, new developments with a very broad spectrum of applications, such as wavelets, spline functions, curve and surface subdivisions, sampling, and learning theory, have found their mathematical home in biomedical data analysis.This book gives a new and integrated introduction to quantitative medical data analysis from the viewpoint of biomathematicians, biostatisticians, and bioinformaticians. It offers a definitive resource to bridge the disciplines of mathematics, statistics, and biomedical sciences. Topics include mathematical models for cancer invasion and clinical sciences, data mining techniques and subset selection in data analysis, survival data analysis and survival models for cancer patients, statistical analysis and neural network techniques for genomic and proteomic data analysis, wavelet and spline applications for mass spectrometry data preprocessing and statistical computing.
Download or read book Stability Problems for Stochastic Models written by Vladimir V. Kalashnikov and published by Springer. This book was released on 2006-11-15 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: The subject of this book is a new direction in the field of probability theory and mathematical statistics which can be called "stability theory": it deals with evaluating the effects of perturbing initial probabilistic models and embraces quite varied subtopics: limit theorems, queueing models, statistical inference, probability metrics, etc. The contributions are original research articles developing new ideas and methods of stability analysis.
Download or read book American Doctoral Dissertations written by and published by . This book was released on 2001 with total page 776 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Endocrine Disrupters and Carcinogenic Risk Assessment written by Lech Chyczewski and published by IOS Press. This book was released on 2002 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work is devoted to the study of the endocrine-related effects on human health with special reference to carcinogenesis, and to the assessment of carcinogenic risk. After providing basic information at the general, cellular and molecular levels, the contents focus on the paradigm of biologically-based risk assessment, as developed form physiologically-based toxicokinetic models. The analysis of this material is proposed as the novel parameters for developing biologically-based models of carcinogenesis, considered to be more relevant to risk assessment than traditional approaches.
Download or read book Handbook of Cancer Models with Applications written by W. Y. Tan and published by World Scientific. This book was released on 2008 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Composed of contributions from an international team of leading researchers, this book pulls together the most recent research results in the field of cancer modeling to provide readers with the most advanced mathematical models of cancer and their applications.Topics included in the book cover oncogenetic trees, stochastic multistage models of carcinogenesis, effects of ionizing radiation on cell cycle and genomic instability, induction of DNA damage by ionizing radiation and its repair, epigenetic cancer models, bystander effects of radiation, multiple pathway models of human colon cancer, and stochastic models of metastasis. The book also provides some important applications of cancer models to the assessment of cancer risk associated with various hazardous environmental agents, to cancer screening by MRI, and to drug resistance in cancer chemotherapy. An updated statistical design and analysis of xenograft experiments as well as a statistical analysis of cancer occult clinical data are also provided.The book will serve as a useful source of reference for researchers in biomathematics, biostatistics and bioinformatics; for clinical investigators and medical doctors employing quantitative methods to develop procedures for cancer diagnosis, prevention, control and treatment; and for graduate students.
Download or read book Statistical Analysis of Ecotoxicity Studies written by John W. Green and published by John Wiley & Sons. This book was released on 2018-07-05 with total page 743 pages. Available in PDF, EPUB and Kindle. Book excerpt: A guide to the issues relevant to the design, analysis, and interpretation of toxicity studies that examine chemicals for use in the environment Statistical Analysis of Ecotoxicity Studies offers a guide to the design, analysis, and interpretation of a range of experiments that are used to assess the toxicity of chemicals. While the book highlights ecotoxicity studies, the methods presented are applicable to the broad range of toxicity studies. The text contains myriad datasets (from laboratory and field research) that clearly illustrate the book's topics. The datasets reveal the techniques, pitfalls, and precautions derived from these studies. The text includes information on recently developed methods for the analysis of severity scores and other ordered responses, as well as extensive power studies of competing tests and computer simulation studies of regression models that offer an understanding of the sensitivity (or lack thereof) of various methods and the quality of parameter estimates from regression models. The authors also discuss the regulatory process indicating how test guidelines are developed and review the statistical methodology in current or pending OECD and USEPA ecotoxicity guidelines. This important guide: Offers the information needed for the design and analysis to a wide array of ecotoxicity experiments and to the development of international test guidelines used to assess the toxicity of chemicals Contains a thorough examination of the statistical issues that arise in toxicity studies, especially ecotoxicity Includes an introduction to toxicity experiments and statistical analysis basics Includes programs in R and excel Covers the analysis of continuous and Quantal data, analysis of data as well as Regulatory Issues Presents additional topics (Mesocosm and Microplate experiments, mixtures of chemicals, benchmark dose models, and limit tests) as well as software Written for directors, scientists, regulators, and technicians, Statistical Analysis of Ecotoxicity Studies provides a sound understanding of the technical and practical issues in designing, analyzing, and interpreting toxicity studies to support or challenge chemicals for use in the environment.
Download or read book Statistics and Experimental Design for Toxicologists Third Edition written by Shayne C. Gad and published by CRC Press. This book was released on 1998-08-14 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book serves as a primary text for students of pharmacology, toxicology, and biology, and as a practical handbook to support the daily operations of the toxicology laboratory and researcher. This edition retains the structure of earlier editions, but has been extensively revised to provide both the student and the working toxicologist with the necessary tools for the rigorous and critical design of studies and analysis of experimental data. Assuming only basic mathematical skills as a starting point, Statistics and Experimental Design for Toxicologists provides a thorough and exhaustive introduction to the statistical methods available to and used in the discipline. A worked, practical example from the field is provided for each technique presented. Written from a toxicologist's perspective, this book provides both the methodological tools necessary to analyze experimental toxicology data and the insight to know when to use them.
Download or read book Statistics and Experimental Design for Toxicologists and Pharmacologists Fourth Edition written by Shayne C. Gad and published by CRC Press. This book was released on 2005-07-18 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: Purposefully designed as a resource for practicing and student toxicologists, Statistics and Experimental Design for Toxicologists and Pharmacologists, Fourth Edition equips you for the regular statistical analysis of experimental data. Starting with the assumption of basic mathematical skills and knowledge, the author supplies a complete and systematic yet practical introduction to the statistical methodologists available for, and used in, the discipline. For every technique presented, a worked example from toxicology is also presented. See what's new in the Fourth Edition: The first practical guide to performing meta analysis allowing for using the power inherent in multiple similar studies Coverage of Bayesian analysis and data analysis in pharmacology and toxicology Almost 200 problems with solutions Discussion of analysis of receptor binding assays, safety pharmacology assays and other standard types conducted in pharmacology A new chapter explaining the basics of Good Laboratory Practices (GLPs) For those with computer skills, this edition has been enhanced with the addition of basic SAS Written specifically for toxicologists and pharmacologists, the author draws on more than 30 years of experience to provide understanding of the philosophical underpinnings for the overall structure of analysis. The book's organization fosters the ordered development of skills and yet still facilitates ease of access to information as needed. This Fourth Edition gives you the tools necessary to perform rigorous and critical analysis of experimental data and the insight to know when to use them.
Download or read book Stochastic Models of Tumor Latency and Their Biostatistical Applications written by Andrej Yu Yakovlev and published by World Scientific. This book was released on 1996 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: This research monograph discusses newly developed mathematical models and methods that provide biologically meaningful inferences from data on cancer latency produced by follow-up and discrete surveillance studies. Methods for designing optimal strategies of cancer surveillance are systematically presented for the first time in this book. It offers new approaches to the stochastic description of tumor latency, employs biologically-based models for making statistical inference from data on tumor recurrence and also discusses methods of statistical analysis of data resulting from discrete surveillance strategies. It also offers insight into the role of prognostic factors based on the interpretation of their effects in terms of parameters endowed with biological meaning, as well as methods for designing optimal schedules of cancer screening and surveillance. Last but not least, it discusses survival models allowing for cure rates and the choice of optimal treatment based on covariate information, and presents numerous examples of real data analysis.
Download or read book ICRDB Cancergram written by and published by . This book was released on 1985 with total page 24 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Journal written by National Cancer Institute (U.S.) and published by . This book was released on 1978 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt:
