Download or read book How the Immune System Recognizes Self and Nonself written by Daisuke Kitamura and published by Springer Science & Business Media. This book was released on 2008-04-08 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: How do you discriminate yourself from other people? This question must sound odd to you since you easily recognize others at a glance and, without any effort, would not mistake them for yourself. However, it is not always easy for some people to discriminate themselves from others. For example, patients with schi- phrenia often talk with “others” living inside themselves. Thus it is likely that n- mally your brain actively recognizes and remembers the information belonging to yourself and discriminates it from the information provided by others, although you are not conscious of it. This brain function must have been particularly important for most animals to protect their lives from enemies and for species to survive through evolution. Similarly, higher organisms have also acquired their immune system through evolution that discriminates nonself pathogens and self-body to protect their lives from pathogens such as bacteria or viruses. The brain system may distinguish integrated images of self and nonself created from many inputs, such as vision, sound, smell, and others. The immune system recognizes and distinguishes a variety of structural features of self and nonself components. The latter actually include almost everything but self: for example, bacteria, viruses, toxins, pollens, chemicals, transplanted organs, and even tumor cells derived from self-tissue. To this end the immune system recruits different kinds of immune cells, such as B and T lymphocytes, natural killer (NK) cells, dendritic cells, and macrophages.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Limits of the Self written by Thomas Pradeu and published by OUP USA. This book was released on 2012-02-27 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunology asserts that an individual can be defined through self and nonself. Thomas Pradeu argues that this theory is inadequate, because immune responses to self constituents and immune tolerance of foreign entities are the rule, not the exception.
Download or read book Janeway s Immunobiology written by Kenneth Murphy and published by Garland Science. This book was released on 2010-06-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Download or read book Self and Non Self in Early Buddhism written by Joaquín Pérez-Remón and published by Walter de Gruyter. This book was released on 2012-10-25 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sinceits founding by Jacques Waardenburg in 1971, Religion and Reason has been a leading forum for contributions on theories, theoretical issues and agendas related to the phenomenon and the study of religion. Topics include (among others) category formation, comparison, ethnophilosophy, hermeneutics, methodology, myth, phenomenology, philosophy of science, scientific atheism, structuralism, and theories of religion. From time to time the series publishes volumes that map the state of the art and the history of the discipline.
Download or read book The Immune Self written by Alfred I. Tauber and published by Cambridge University Press. This book was released on 1994 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Immune Self is the first extended philosophical critique of immunology.
Download or read book Being No One written by Thomas Metzinger and published by MIT Press. This book was released on 2004-08-20 with total page 896 pages. Available in PDF, EPUB and Kindle. Book excerpt: According to Thomas Metzinger, no such things as selves exist in the world: nobody ever had or was a self. All that exists are phenomenal selves, as they appear in conscious experience. The phenomenal self, however, is not a thing but an ongoing process; it is the content of a "transparent self-model." In Being No One, Metzinger, a German philosopher, draws strongly on neuroscientific research to present a representationalist and functional analysis of what a consciously experienced first-person perspective actually is. Building a bridge between the humanities and the empirical sciences of the mind, he develops new conceptual toolkits and metaphors; uses case studies of unusual states of mind such as agnosia, neglect, blindsight, and hallucinations; and offers new sets of multilevel constraints for the concept of consciousness. Metzinger's central question is: How exactly does strong, consciously experienced subjectivity emerge out of objective events in the natural world? His epistemic goal is to determine whether conscious experience, in particular the experience of being someone that results from the emergence of a phenomenal self, can be analyzed on subpersonal levels of description. He also asks if and how our Cartesian intuitions that subjective experiences as such can never be reductively explained are themselves ultimately rooted in the deeper representational structure of our conscious minds.
Download or read book Self No Self written by Mark Siderits and published by OUP Oxford. This book was released on 2013-01-31 with total page 350 pages. Available in PDF, EPUB and Kindle. Book excerpt: The nature and reality of self is a subject of increasing prominence among Western philosophers of mind and cognitive scientists. It has also been central to Indian and Tibetan philosophical traditions for over two thousand years. It is time to bring the rich resources of these traditions into the contemporary debate about the nature of self. This volume is the first of its kind. Leading philosophical scholars of the Indian and Tibetan traditions join with leading Western philosophers of mind and phenomenologists to explore issues about consciousness and selfhood from these multiple perspectives. Self, No Self? is not a collection of historical or comparative essays. It takes problem-solving and conceptual and phenomenological analysis as central to philosophy. The essays mobilize the argumentative resources of diverse philosophical traditions to address issues about the self in the context of contemporary philosophy and cognitive science. Self, No Self? will be essential reading for philosophers and cognitive scientists interested in the nature of the self and consciousness, and will offer a valuable way into the subject for students.
Download or read book Self and No Self written by Dale Mathers and published by Routledge. This book was released on 2013-12-16 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: This collection explores the growing interface between Eastern and Western concepts of what it is to be human from analytical psychology, psychoanalytic and Buddhist perspectives. The relationship between these different approaches has been discussed for decades, with each discipline inviting its followers to explore the depths of the psyche and confront the sometimes difficult psychological experiences that can emerge during any in-depth exploration of mental processes. Self and No-Self considers topics discussed at the Self and No-Self conference in Kyoto, Japan in 2006. International experts from practical and theoretical backgrounds compare and contrast Buddhist and psychological traditions, providing a fresh insight on the relationship between the two. Areas covered include: the concept of self Buddhist theory and practice psychotherapeutic theory and practice mysticism and spirituality myth and fairy tale. This book explains how a Buddhist approach can be integrated into the clinical setting and will interest seasoned practitioners and theoreticians from analytical psychology, psychoanalytic and Buddhist backgrounds, as well as novices in these fields.
Download or read book Attention Not Self written by Jonardon Ganeri and published by Oxford University Press. This book was released on 2017 with total page 403 pages. Available in PDF, EPUB and Kindle. Book excerpt: Jonardon Ganeri presents an account of mind in which attention, not self, explains the experiential and normative situatedness of human beings in the world. Attention consists in an organisation of awareness and action at the centre of which there is neither a practical will nor a phenomenological witness. Attention performs two roles in experience, a selective role of placing and a focal role of access. Attention improves our epistemic standing, because it is in the nature of attention to settle on what is real and to shun what is not real. When attention is informed by expertise, it is sufficient for knowledge. That gives attention a reach beyond the perceptual: for attention is a determinable whose determinates include the episodic memory from which our narrative identities are made, the empathy for others that situates us in a social world, and the introspection that makes us self-aware. Empathy is other-directed attention, placed on you and focused on your states of mind; it is akin to listening. Empathetic attention is central to a range of experiences that constitutively require a contrast between oneself and others, all of which involve an awareness of oneself as the object of another's attention. An analysis of attention as mental action gainsays authorial conceptions of self, because it is the nature of intending itself, effortful attention in action, to settle on what to do and to shun what not to do. In ethics, a conception of persons as beings with a characteristic capacity for attention offers hope for resolution in the conflict between individualism and impersonalism. Attention, Not Self is a contribution to a growing body of work that studies the nature of mind from a place at the crossroads of three disciplines: philosophy in the analytical and phenomenological traditions, contemporary cognitive science and empirical work in cognitive psychology, and Buddhist theoretical literature.
Download or read book Thinking about Oneself written by Kristina Musholt and published by MIT Press. This book was released on 2015-07-17 with total page 229 pages. Available in PDF, EPUB and Kindle. Book excerpt: A novel theory of self-consciousness and its development that integrates philosophical considerations with recent findings in the empirical sciences. In this book, Kristina Musholt offers a novel theory of self-consciousness, understood as the ability to think about oneself. Traditionally, self-consciousness has been central to many philosophical theories. More recently, it has become the focus of empirical investigation in psychology and neuroscience. Musholt draws both on philosophical considerations and on insights from the empirical sciences to offer a new account of self-consciousness—the ability to think about ourselves that is at the core of what makes us human. Examining theories of nonconceptual content developed in recent work in the philosophy of cognition, Musholt proposes a model for the gradual transition from self-related information implicit in the nonconceptual content of perception and other forms of experience to the explicit representation of the self in conceptual thought. A crucial part of this model is an analysis of the relationship between self-consciousness and intersubjectivity. Self-consciousness and awareness of others, Musholt argues, are two sides of the same coin. After surveying the philosophical problem of self-consciousness, the notion of nonconceptual content, and various proposals for the existence of nonconceptual self-consciousness, Musholt argues for a non-self-representationalist theory, according to which the self is not part of the representational content of perception and bodily awareness but part of the mode of presentation. She distinguishes between implicitly self-related information and explicit self-representation, and describes the transitions from the former to the latter as arising from a complex process of self–other differentiation. By this account, both self-consciousness and intersubjectivity develop in parallel.
Download or read book No Self No Problem written by Chris Niebauer and published by Hierophant Publishing. This book was released on 2019-09-03 with total page 193 pages. Available in PDF, EPUB and Kindle. Book excerpt: While in grad school in the early 1990s, Chris Niebauer began to notice striking parallels between the latest discoveries in psychology, neuroscience, and the teachings of Buddhism, Taoism, and other schools of Eastern thought. When he presented his findings to a professor, his ideas were quickly dismissed as “pure coincidence, nothing more.” Fast-forward 20 years later and Niebauer is a PhD and a tenured professor, and the Buddhist-neuroscience connection he found as a student is practically its own genre in the bookstore. But according to Niebauer, we are just beginning to understand the link between Eastern philosophy and the latest findings in psychology and neuroscience and what these assimilated ideas mean for the human experience. In this groundbreaking book, Niebauer writes that the latest research in neuropsychology is now confirming a fundamental tenet of Buddhism, what is called Anatta, or the doctrine of “no self.” Niebauer writes that our sense of self, or what we commonly refer to as the ego, is an illusion created entirely by the left side of the brain. Niebauer is quick to point out that this doesn't mean that the self doesn't exist but rather that it does so in the same way that a mirage in the middle of the desert exists, as a thought rather than a thing. His conclusions have significant ramifications for much of modern psychological modalities, which he says are spending much of their time trying to fix something that isn’t there. What makes this book unique is that Niebauer offers a series of exercises to allow the reader to experience this truth for him- or herself, as well as additional tools and practices to use after reading the book, all of which are designed to change the way we experience the world—a way that is based on being rather than thinking.
Download or read book You Mean I m Not Lazy Stupid or Crazy written by Kate Kelly and published by Simon and Schuster. This book was released on 2006-04-25 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: A revised and updated edition of the classic self-help book that has served as a lifeline to the millions of adults who have ADHD! With over a quarter million copies in print, You Mean I'm Not Lazy, Stupid or Crazy?! is one of the bestselling books on attention deficit/hyperactivity disorder ever written. There is a great deal of literature about children with ADHD, but what do you do if you have ADHD and aren't a child anymore? This indispensable reference—the first of its kind written for adults with ADHD by adults with ADHD—focuses on the experiences of adults, offering updated information, practical how-tos, and moral support to help readers deal with ADHD. It also explains the diagnostic process that distinguishes ADHD symptoms from normal lapses in memory, lack of concentration or impulsive behavior, offering guidance on how your reframe our view of ADHD and embrace its benefits. Here's what's new: The new ADHD medications and their effectiveness The effects of ADHD on human sexuality The differences between male and female ADHD—including falling estrogen levels and its impact on cognitive function The power of meditation ADHD coaching tricks and tips And the book still includes the tried-and-true advice about: Achieving balance by analyzing one's strengths and weaknesses Getting along in groups, at work and in intimate and family relationships—including how to decrease discord and chaos Learning the mechanics and methods for getting organized and improving memory Seeking professional help, including therapy and medication
Download or read book From Self to Self written by Leo Hartong and published by New Harbinger Publications. This book was released on 2005-09-18 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: A compilation of expressions, questions and answers that came about in response to Leo's highly praised first book Awakening to the Dream. Leo writes with characteristic insight and uses metaphor to illuminate the paradoxical and apparently confusing nature of non-dual reality. His original writing is reinforced by a vast knowledge of non-duality in other spiritual traditions and he weaves these together with his own direct path to present clear pointers to contemporary seekers. An appropriately chosen quotation taken from various sources appears at the end of each short chapter. Also included at the end of the book is the full text of the Hsin-hsin Ming by the third Chan patriarch Seng-ts'an. “The words in this book repeatedly point to the essence which knows the reading as it takes place. Rather than an encouragement to follow a lengthy path, it is an invitation to step off the path. It does not point to 'your' awareness, but to Awareness itself in which the idea of 'you' appears. It does not point to 'your' beingness, but to the undeniable Beingness that appears as you.”
Download or read book Inflammation and Metastasis written by Yoshiro Maru and published by Springer. This book was released on 2016-07-25 with total page 515 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the latest information on cancer metastasis from the standpoint of inflammation, especially innate immune reactions caused by endogenous mediators but not exogenous pathogens, with ideas on how to understand the complicated mechanisms of metastasis as well as to interpret therapeutic targets. The book includes the topic of the emerging roles of endogenous TLR4 ligands whose functions are shared intriguingly by metastasis and auto-inflammatory diseases such as rheumatoid arthritis. For example, most cancer therapies established so far are effective initially. However, they eventually face the great obstacles of drug resistance, immune evasion, and metastatic progression. One of the endogenous TLR4 ligands is thought to contribute to all three processes. The most important features of the book are to explain a concept of homeostatic inflammation, disturbance of which in the lungs gives rise to the establishment of a pre-metastatic pulmonary microenvironment based on primary tumor-mediated hijacking of the innate immune defense system against respiratory infection. In addition, structure-based thinking is another important feature of this book. It is proposed that inflammation forms a functional triangle with angiogenesis and coagulation, in the center of which cancer is located. Given the proposal of precision medicine by President Obama in the United States in 2015 and the recent success of immune-modulator-based therapy, this book will appeal to researchers in a variety of fields with the title of the book connecting the worst disease (metastasis) and the most fundamental event (inflammation) that is common to many diseases.
Download or read book The Non Sovereign Self Responsibility and Otherness written by Rosine Kelz and published by Springer. This book was released on 2016-02-09 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing on Hannah Arendt, Judith Butler and Stanley Cavell, this book addresses contemporary theoretical and political debates in a broader comparative perspective and rearticulates the relationship between ethics and politics by highlighting those who are currently excluded from our notions of political community.
Download or read book Intrinsic Motivation written by Edward L. Deci and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: As I begin to write this Preface, I feel a rush of excitement. I have now finished the book; my gestalt is coming into completion. Throughout the months that I have been writing this, I have, indeed, been intrinsically motivated. Now that it is finished I feel quite competent and self-determining (see Chapter 2). Whether or not those who read the book will perceive me that way is also a concern of mine (an extrinsic one), but it is a wholly separate issue from the intrinsic rewards I have been experiencing. This book presents a theoretical perspective. It reviews an enormous amount of research which establishes unequivocally that intrinsic motivation exists. Also considered herein are various approaches to the conceptualizing of intrinsic motivation. The book concentrates on the approach which has developed out of the work of Robert White (1959), namely, that intrinsically motivated behaviors are ones which a person engages in so that he may feel competent and self-determining in relation to his environment. The book then considers the development of intrinsic motiva tion, how behaviors are motivated intrinsically, how they relate to and how intrinsic motivation is extrinsically motivated behaviors, affected by extrinsic rewards and controls. It also considers how changes in intrinsic motivation relate to changes in attitudes, how people attribute motivation to each other, how the attribution process is motivated, and how the process of perceiving motivation (and other internal states) in oneself relates to perceiving them in others.
