Download or read book Risk of Breast Cancer Associated with Reproductive and Fertility Factors According to a Family History of Breast Cancer written by Thomas Sellers and published by . This book was released on 1999 with total page 45 pages. Available in PDF, EPUB and Kindle. Book excerpt: Early age at menarche, nulliparity, late age at first birth, and late age at menopause have been consistently associated with an increased risk of breast cancer. The association of these factors in addition to other reproductive and fertility factors with risk of breast cancer is less well characterized in women with a family history of breast cancer. The scope of this research is to examine the association of reproductive and fertility factors with risk of breast cancer among sisters, daughters, granddaughters, and nieces of 426 breast cancer probands as well as women who married into the 426 families. We found that women who have used oral contraceptives and also have a first-degree relative with breast cancer were at significantly increased risk of breast cancer compared to genetically comparable women who never used oral contraceptives. The association was particularly strong in families with multiple cases of breast and ovarian cancer and for oral contraceptive use before 1975. Further follow-up is needed of younger women who used oral contraceptives after 1975. These findings are very important in light of the published recommendations that women with a hereditary predisposition to breast and ovarian cancer take oral contraceptives to lower risk of ovarian cancer.
Download or read book The Role of Genetics in Breast and Reproductive Cancers written by Piri Welcsh and published by Springer Science & Business Media. This book was released on 2009-10-03 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume will explore the latest findings in research into the genetics of breast and reproductive cancers, covering the epidemiological aspects of these cancers, their etiology, the effect of environment on genes and cancer etiology, and how research in this area can lead to development of preventative measures and treatments.
Download or read book A Family History of Breast Cancer written by Dawn Marie Grabrick and published by . This book was released on 2001 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Family History of Breast Cancer as a Determinant of the Risk of Developing Endometrial and Ovarian Cancers written by Niloufar Neely Kazerouni and published by . This book was released on 2002 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Breast Cancer Fertility Preservation and Reproduction written by Nicoletta Biglia and published by Springer. This book was released on 2015-05-06 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive overview on issues surrounding fertility in patients who have been diagnosed with breast cancer or belong to a high-risk population. The impact of breast cancer treatment on fertility is clearly explained and all the available options for fertility preservation are discussed, including the use of assisted reproduction technologies. Guidance is offered on family planning and on management options when breast cancer arises during pregnancy and when pregnancy occurs after breast cancer. Answers are provided to a wide range of key questions, including: What is the impact of pregnancy after breast cancer on prognosis? What advice should be given on the timing of pregnancy in relation to chemotherapy and endocrine treatment? What is the effect of reducing the duration of endocrine treatment to allow an earlier attempt at pregnancy? Is breast feeding possible? Medical treatments of breast cancer have a huge impact on fertility. While many procedures can be applied to preserve fertility, all must be put into action within the very short time available before starting treatment. Any delay in referral of a woman wishing to preserve her fertility to an ART center with experience in oncologic patients may preclude the possibility of a future pregnancy. In addition, an increasing number of high-risk patients are asking questions about their reproductive life, from choice of contraception to the risks of assisted reproduction techniques. Physicians will find this book an invaluable aid in providing flawless counseling to their patients and ensuring that they receive optimal management.
Download or read book Risk Factors for Breast Cancer written by and published by Am Cncl on Science, Health. This book was released on with total page 27 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Relative Risk written by Nancy C. Baker and published by Penguin Mass Market. This book was released on 1992 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Here is an emphatic, reassuring, and hopeful guide for those who face an increased risk of developing breast cancer. The author explores the realistic assessment of risks; discusses key diet and health factors that can improve the chances of avoiding the disease; and provides emotional and psychological support for women at risk.
Download or read book Environmental and Lifestyle Influences on Breast Cancer Risk written by Mary-Claire King and published by . This book was released on 2000 with total page 22 pages. Available in PDF, EPUB and Kindle. Book excerpt: Women with inherited mutations in BRCAl or BRCA2 have significantly elevated risks of breast cancer. However, not all women with inherited BRCAl or BRCA2 mutations develop breast or ovarian cancer, and among those who do, ages at cancer onset vary widely even within the same family. If a woman with a BRCAl or BRCA2 mutation remains free of breast cancer for many years, it is possible that her status is due to chance, to modifying genes segregating in some families, or to environmental factors that influence risk. In this project, we evaluate environmental and lifestyle factors that could influence the impact of mutations in BRCA I and BRCA2 on disease risk. It is possible that such co-factors identified among genetically predisposed women may be generalized to women who have not inherited predisposition to breast or ovarian cancer, because clinically and biologically, inherited cancer is virtually indistinguishable from its far more common, non-inherited counterpart.
Download or read book Hereditary Breast Cancer written by Claudine Isaacs and published by CRC Press. This book was released on 2007-09-19 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Intended for medical oncologists, surgeons, obstetricians, gynecologists, geneticists, genetic counselors, and primary care physicians, this text presents the epidemiological, biological, and clinical issues associated with hereditary breast cancer. It offers clear guidance on the application and utilization of cancer risk assessment models, geneti
Download or read book Diet and Breast Cancer written by American Institute for Cancer Research and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fourth annual American Institute for Cancer Research (AICR) conference on diet, nutrition and cancer was held at the L'Enfant Plaza Hotel in Washington, D. C. , September 2~3, 1993. In keeping with present concerns and in line with current trends, the theme was "Diet and Breast Cancer. " This proceedings volume is comprised of chapters from the platform presentations of the two day conference and abstracts from the poster session held at the end of the first day. Experimentally, there is sufficient evidence to support a relationship between dietary fat and the risk of breast cancer. A meta-analysis was provided by data from 114 experiments with over 10,000 animals, divided into groups fed ad libitum on diets with different levels or sources of fat, or different levels of energy restriction. This exercise suggested that linoleic acid was a major determinant of mammary tumor development but that other fatty acids also enhanced mammary tumor development in animals. However, as mentioned by several speakers, results from epidemiological studies often are conflicting, thus leading to confusion among both health professionals and the public. Surveys of specific populations which have migrated from countries with low breast cancer rates to those with higher rates are often some of the most compelling studies with respect to a high fat diet-breast cancer association. Nonetheless, various cohort and prospective studies, some quite large, did not appear to show a relationship between consumption of fat (any type) and breast cancer.
Download or read book Breast Cancer in Young Women written by Nancy Klauber-DeMore and published by IOS Press. This book was released on 2006 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: This publication gives a comprehensive overview of breast cancer in young women for all members of the healthcare team who treat women with breast cancer. Breast cancer requires multidisciplinary management, and as such this book provides input from epidemiology, basic science, surgical oncology, radiation oncology, medical oncology, plastic and reconstructive surgery, genetics, reproductive endocrinology, psychology and nursing. Because breast cancer in young women occurs during the reproductive years, additional emphasis is placed on managing breast cancer in pregnant patients, as well as reproductive options for breast cancer survivors. The contributors to this volume comprise 30 experts from 6 academic institutions across 10 disciplines. By presenting a clear and comprehensive review of all aspects of breast cancer treatment in young women, the contributors hope to have provided a valuable resource to assist with patient care for all members of the multidisciplinary breast cancer team.
Download or read book Breast Cancer Metastasis and Drug Resistance written by Aamir Ahmad and published by Springer Nature. This book was released on 2019-08-27 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.
Download or read book The Role of Genetics in Breast and Reproductive Cancers written by Piri Welcsh and published by Springer. This book was released on 2009-11-05 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume will explore the latest findings in research into the genetics of breast and reproductive cancers, covering the epidemiological aspects of these cancers, their etiology, the effect of environment on genes and cancer etiology, and how research in this area can lead to development of preventative measures and treatments.
Download or read book Genetic Counseling in Breast Cancer written by Beth N. Peshkin and published by IOS Press. This book was released on 2007 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: A testament to how far the field of genetic counseling for breast cancer susceptibility has advanced since the mid-1990s, following the cloning of two major breast (and ovarian) cancer susceptibility genes, BRCA1 and BRCA2.
Download or read book Environmental and Lifestyle Influences on Breast Cancer Risk Clues from Women with Inherited Mutations in BRCA1 and BRCA2 written by and published by . This book was released on 2001 with total page 19 pages. Available in PDF, EPUB and Kindle. Book excerpt: This project aims to identify potentially preventable environmental influences on breast and ovarian cancer by focusing on a population of women with genetically inherited predisposition to the disease. This is an extension of our ongoing research into the genetics of breast and ovarian cancer among Jewish women in the New York City area. The IDEA project centered on female relatives of breast cancer patients with confirmed mutations in BRCAl or BRCA2. Each relative provided a blood sample for mutation testing and completed an extensive questionnaire addressing epidemiologic factors in breast cancer risk. Among participants, inherited mutations in BRCAl and BRCA2 were more frequent in women with a younger breast cancer diagnosis and in women with a breast and/or ovarian cancer family history. Breast cancer risks increased over time among women with mutations, suggesting the influence of environmental factors. The experiences and exposures of women with mutations who did and did not develop breast or ovarian cancer were compared to identify factors that ameliorate or exacerbate risk in this high-risk group. These risk factors may be generalized to women without inherited vulnerability to breast or ovarian cancer, as inherited cancer is virtually indistinguishable, clinically and biologically, from its non inherited counterpart.
Download or read book Understanding Breast Cancer Genetics written by Barbara T. Zimmerman and published by Univ. Press of Mississippi. This book was released on 2004 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Health & Sickness -- Consumer Health This book by a scientist whose background is in cellular and molecular biology examines the fearsome disease that strikes one in eight women in the United States. Although women are more likely to die of heart disease or of lung cancer, a diagnosis of breast cancer is the medical pronouncement that a woman is most likely to fear. It kills more than 40,000 Americans annually. Why are some women more vulnerable than others? The interplay between genetics and environment is suspected. Thus this book for general readers will help them understand the genetic bases of both sporadic and inherited breast cancers. Although only five to ten percent of breast cancer patients have inherited mutations in these genes, all women need to understand the genetic implications of the disease. In clear, concise language Barbara T. Zimmerman guides the reader through the complexities, discussing in detail the genes that are known to increase susceptibility and the ways they are passed on. Examining the general biology of breast cancer, Zimmerman describes how sporadic and inherited forms of the disease arise and how the location of the tumors can affect the body. She discusses genetic mutations and their roles in the development of tumors and tells how these potentially cancer-inducing genes were discovered. Covered too are the issues of risk, prevention, screening, diagnosis, therapy, and genetic testing and counseling. Zimmerman concludes with a comprehensive analysis of current research and with an emphasis on how a woman's understanding of inherited breast cancer can help doctors seeking to design better methods for prevention and therapy. A useful list of resources for further information about the genetic causes of breast cancer is included. Barbara T. Zimmerman did her graduate work in experimental pathology and her post-doctoral research in the cellular and molecular processes of disease. Widely published, she is the manager of the Denver-based firm Biomedical Communication and Consulting.
Download or read book Breast Cancer written by I. Craig Henderson and published by Oxford University Press, USA. This book was released on 2015 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an in-depth understanding of the biology of breast cancer, the natural history of the disease, the use of molecular markers, the interpretation of clinical trial data, and the integration of multiple therapeutic modalities. Outcomes of clinical trials and details about commonly used drug regimens, drug dosage, and the expected side effects are summarised.
