Download or read book Risk Assessment and Evaluation of Predictions written by Mei-Ling Ting Lee and published by Springer Science & Business Media. This book was released on 2013-12-11 with total page 446 pages. Available in PDF, EPUB and Kindle. Book excerpt: Methods of risk analysis and the outcome of particular evaluations and predictions are covered in detail in this proceedings volume, whose contributions are based on invited presentations from Professor Mei-Ling Ting Lee's 2011 symposium on Risk Analysis and the Evaluation of Predictions. This symposium was held at the University of Maryland in October of 2011. Risk analysis is the science of evaluating health, environmental, and engineering risks resulting from past, current, or anticipated, future activities. The use of these evaluations include to provide information for determining regulatory actions to limit risk, present scientific evidence in legal settings, evaluate products and potential liabilities within private organizations, resolve World Trade disputes amongst nations, and educate the public concerning particular risk issues. Risk analysis is an interdisciplinary science that relies on epidemiology and laboratory studies, collection of exposure and other field data, computer modeling, and related social, economic and communication considerations. In addition, social dimensions of risk are addressed by social scientists.

Download or read book Occupational Health and Safety in the Care and Use of Nonhuman Primates written by National Research Council and published by National Academies Press. This book was released on 2003-06-13 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of occupational health and safety constantly changes, especially as it pertains to biomedical research. New infectious hazards are of particular importance at nonhuman-primate facilities. For example, the discovery that B virus can be transmitted via a splash on a mucous membrane raises new concerns that must be addressed, as does the discovery of the Reston strain of Ebola virus in import quarantine facilities in the U.S. The risk of such infectious hazards is best managed through a flexible and comprehensive Occupational Health and Safety Program (OHSP) that can identify and mitigate potential hazards. Occupational Health and Safety in the Care and Use of Nonhuman Primates is intended as a reference for vivarium managers, veterinarians, researchers, safety professionals, and others who are involved in developing or implementing an OHSP that deals with nonhuman primates. The book lists the important features of an OHSP and provides the tools necessary for informed decision-making in developing an optimal program that meets all particular institutional needs.

Download or read book Science and Judgment in Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 1994-01-01 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: The public depends on competent risk assessment from the federal government and the scientific community to grapple with the threat of pollution. When risk reports turn out to be overblownâ€"or when risks are overlookedâ€"public skepticism abounds. This comprehensive and readable book explores how the U.S. Environmental Protection Agency (EPA) can improve its risk assessment practices, with a focus on implementation of the 1990 Clean Air Act Amendments. With a wealth of detailed information, pertinent examples, and revealing analysis, the volume explores the "default option" and other basic concepts. It offers two views of EPA operations: The first examines how EPA currently assesses exposure to hazardous air pollutants, evaluates the toxicity of a substance, and characterizes the risk to the public. The second, more holistic, view explores how EPA can improve in several critical areas of risk assessment by focusing on cross-cutting themes and incorporating more scientific judgment. This comprehensive volume will be important to the EPA and other agencies, risk managers, environmental advocates, scientists, faculty, students, and concerned individuals.

Download or read book The Wiley Handbook of What Works in Violence Risk Management written by J. Stephen Wormith and published by John Wiley & Sons. This book was released on 2020-02-10 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to the theory, research and practice of violence risk management The Wiley Handbook of What Works in Violence Risk Management: Theory, Research and Practice offers a comprehensive guide to the theory, research and practice of violence risk management. With contributions from a panel of noted international experts, the book explores the most recent advances to the theoretical understanding, assessment and management of violent behavior. Designed to be an accessible resource, the highly readable chapters address common issues associated with violent behavior such as alcohol misuse and the less common issues for example offenders with intellectual disabilities. Written for both those new to the field and professionals with years of experience, the book offers a wide-ranging review of who commit acts of violence, their prevalence in society and the most recent explanations for their behavior. The contributors explore various assessment approaches and highlight specialized risk assessment instruments. The Handbook provides the latest evidence on effective treatment and risk management and includes a number of well-established and effective treatment interventions for violent offenders. This important book: Contains an authoritative and comprehensive guide to the topic Includes contributions from an international panel of experts Offers information on violence risk formulation Reveals the most recent techniques in violence risk assessment Explains what works in violence intervention Reviews specialty clinical assessments Written for clinicians and other professionals in the field of violence prevention and assessment, The Wiley Handbook of What Works in Violence Risk Management is unique in its approach because it offers a comprehensive review of the topic rather than like other books on the market that take a narrower view.

Download or read book Personalized and Precision Medicine Informatics written by Terrence Adam and published by Springer Nature. This book was released on 2019-09-17 with total page 349 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book adopts an integrated and workflow-based treatment of the field of personalized and precision medicine (PPM). Outlined within are established, proven and mature workflows as well as emerging and highly-promising opportunities for development. Each workflow is reviewed in terms of its operation and how they are enabled by a multitude of informatics methods and infrastructures. The book goes on to describe which parts are crucial to discovery and which are essential to delivery and how each of these interface and feed into one-another. Personalized and Precision Medicine Informatics provides a comprehensive review of the integrative as well as interpretive nature of the topic and brings together a large body of literature to define the topic and ensure that this is the key reference for the topic. It is an unique contribution that is positioned to be an essential guide for both PPM experts and non-experts, and for both informatics and non-informatics professionals.

Download or read book Knowledge in Risk Assessment and Management written by Terje Aven and published by John Wiley & Sons. This book was released on 2018-02-20 with total page 359 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exciting new developments in risk assessment and management Risk assessment and management is fundamentally founded on the knowledge available on the system or process under consideration. While this may be self-evident to the laymen, thought leaders within the risk community have come to recognize and emphasize the need to explicitly incorporate knowledge (K) in a systematic, rigorous, and transparent framework for describing and modeling risk. Featuring contributions by an international team of researchers and respected practitioners in the field, this book explores the latest developments in the ongoing effort to use risk assessment as a means for characterizing knowledge and/or lack of knowledge about a system or process of interest. By offering a fresh perspective on risk assessment and management, the book represents a significant contribution to the development of a sturdier foundation for the practice of risk assessment and for risk-informed decision making. How should K be described and evaluated in risk assessment? How can it be reflected and taken into account in formulating risk management strategies? With the help of numerous case studies and real-world examples, this book answers these and other critical questions at the heart of modern risk assessment, while identifying many practical challenges associated with this explicit framework. This book, written by international scholars and leaders in the field, and edited to make coverage both conceptually advanced and highly accessible: Offers a systematic, rigorous and transparent perspective and framework on risk assessment and management, explicitly strengthening the links between knowledge and risk Clearly and concisely introduces the key risk concepts at the foundation of risk assessment and management Features numerous cases and real-world examples, many of which focused on various engineering applications across an array of industries Knowledge of Risk Assessment and Management is a must-read for risk assessment and management professionals, as well as graduate students, researchers and educators in the field. It is also of interest to policy makers and business people who are eager to gain a better understanding of the foundations and boundaries of risk assessment, and how its outcomes should be used for decision-making.

Download or read book QSAR in Safety Evaluation and Risk Assessment written by Huixiao Hong and published by Elsevier. This book was released on 2023-08-12 with total page 566 pages. Available in PDF, EPUB and Kindle. Book excerpt: QSAR in Safety Evaluation and Risk Assessment provides comprehensive coverage on QSAR methods, tools, data sources, and models focusing on applications in products safety evaluation and chemicals risk assessment. Organized into five parts, the book covers almost all aspects of QSAR modeling and application. Topics in the book include methods of QSAR, from both scientific and regulatory viewpoints; data sources available for facilitating QSAR models development; software tools for QSAR development; and QSAR models developed for assisting safety evaluation and risk assessment. Chapter contributors are authored by a lineup of active scientists in this field. The chapters not only provide professional level technical summarizations but also cover introductory descriptions for all aspects of QSAR for safety evaluation and risk assessment. Provides comprehensive content about the QSAR techniques and models in facilitating the safety evaluation of drugs and consumer products and risk assesment of environmental chemicals Includes some of the most cutting-edge methodologies such as deep learning and machine learning for QSAR Offers detailed procedures of modeling and provides examples of each model's application in real practice

Download or read book Review of the Department of Homeland Security s Approach to Risk Analysis written by National Research Council and published by National Academies Press. This book was released on 2010-10-10 with total page 160 pages. Available in PDF, EPUB and Kindle. Book excerpt: The events of September 11, 2001 changed perceptions, rearranged national priorities, and produced significant new government entities, including the U.S. Department of Homeland Security (DHS) created in 2003. While the principal mission of DHS is to lead efforts to secure the nation against those forces that wish to do harm, the department also has responsibilities in regard to preparation for and response to other hazards and disasters, such as floods, earthquakes, and other "natural" disasters. Whether in the context of preparedness, response or recovery from terrorism, illegal entry to the country, or natural disasters, DHS is committed to processes and methods that feature risk assessment as a critical component for making better-informed decisions. Review of the Department of Homeland Security's Approach to Risk Analysis explores how DHS is building its capabilities in risk analysis to inform decision making. The department uses risk analysis to inform decisions ranging from high-level policy choices to fine-scale protocols that guide the minute-by-minute actions of DHS employees. Although DHS is responsible for mitigating a range of threats, natural disasters, and pandemics, its risk analysis efforts are weighted heavily toward terrorism. In addition to assessing the capability of DHS risk analysis methods to support decision-making, the book evaluates the quality of the current approach to estimating risk and discusses how to improve current risk analysis procedures. Review of the Department of Homeland Security's Approach to Risk Analysis recommends that DHS continue to build its integrated risk management framework. It also suggests that the department improve the way models are developed and used and follow time-tested scientific practices, among other recommendations.

Download or read book Risk Evaluation and Management written by V.T. Covello and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 543 pages. Available in PDF, EPUB and Kindle. Book excerpt: Public attention has focused in recent years on an array of technological risks to health, safety, and the environment. At the same time, responsibilities for technological risk as sessment, evaluation, and management have grown in both the public and private sectors because of a perceived need to anticipate, prevent, or reduce the risks inherent in modem society. In attempting to meet these responsibilities, legislative, judicial, regulatory, and private sector institutions have had to deal with the extraordinarily complex problems of assessing and balancing risks, costs, and benefits. The need to help society cope with technological risks has given rise to a new intellectual endeavor: the social and behavioral study of issues in risk evaluation and risk management. The scope and complexity of these analyses require a high degree of cooperative effort on the part of specialists from many fields. Analyzing social and behavioral issues requires the efforts of political scientists, sociologists, decision analysts, management scientists, econ omists, psychologists, philosophers, and policy analysts, among others.

Download or read book Risk Analysis written by Terje Aven and published by John Wiley & Sons. This book was released on 2015-09-28 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical guide to the varied challenges presented in the ever-growing field of risk analysis. Risk Analysis presents an accessible and concise guide to performing risk analysis, in a wide variety of field, with minimal prior knowledge required. Forming an ideal companion volume to Aven's previous Wiley text Foundations of Risk Analysis, it provides clear recommendations and guidance in the planning, execution anduse of risk analysis. This new edition presents recent developments related to risk conceptualization, focusing on related issues on risk assessment and their application. New examples are also featured to clarify the reader's understanding in the application of risk analysis and the risk analysis process. Key features: Fully updated to include recent developments related to risk conceptualization and related issues on risk assessments and their applications. Emphasizes the decision making context of risk analysis rather than just computing probabilities Demonstrates how to carry out predictive risk analysis using a variety of case studies and examples. Written by an experienced expert in the field, in a style suitable for both industrial and academic audiences. This book is ideal for advanced undergraduates, graduates, analysts and researchers from statistics, engineering, finance, medicine and physical sciences. Managers facing decision making problems involving risk and uncertainty will also benefit from this book.

Download or read book Predictive Modeling and Risk Assessment written by Rui Costa and published by Springer Science & Business Media. This book was released on 2008-12-02 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: The single most important task of food scientists and the food industry as a whole is to ensure the safety of foods supplied to consumers. Recent trends in global food production, distribution and preparation call for increased emphasis on hygienic practices at all levels and for increased research in food safety in order to ensure a safer global food supply. The ISEKI-Food book series is a collection of books where various aspects of food safety and environmental issues are introduced and reviewed by scientists specializing in the field. In all of the books a special emp- sis was placed on including case studies applicable to each specific topic. The books are intended for graduate students and senior level undergraduate students as well as professionals and researchers interested in food safety and environmental issues applicable to food safety. The idea and planning of the books originates from two working groups in the European thematic network “ISEKI-Food” an acronym for “Integrating Safety and Environmental Knowledge In to Food Studies”. Participants in the ISEKI-Food network come from 29 countries in Europe and most of the institutes and univer- ties involved with Food Science education at the university level are represented. Some international companies and non teaching institutions have also participated in the program. The ISEKI-Food network is coordinated by Professor Cristina Silva at The Catholic University of Portugal, College of Biotechnology (Escola) in Porto. The program has a web site at: http://www. esb. ucp. pt/iseki/.

Download or read book EPA 630 R written by and published by . This book was released on 1998 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Fundamentals of Clinical Data Science written by Pieter Kubben and published by Springer. This book was released on 2018-12-21 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book comprehensively covers the fundamentals of clinical data science, focusing on data collection, modelling and clinical applications. Topics covered in the first section on data collection include: data sources, data at scale (big data), data stewardship (FAIR data) and related privacy concerns. Aspects of predictive modelling using techniques such as classification, regression or clustering, and prediction model validation will be covered in the second section. The third section covers aspects of (mobile) clinical decision support systems, operational excellence and value-based healthcare. Fundamentals of Clinical Data Science is an essential resource for healthcare professionals and IT consultants intending to develop and refine their skills in personalized medicine, using solutions based on large datasets from electronic health records or telemonitoring programmes. The book’s promise is “no math, no code”and will explain the topics in a style that is optimized for a healthcare audience.

Download or read book Issues in Risk Assessment written by National Research Council and published by National Academies Press. This book was released on 1993-02-01 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: The scientific basis, inference assumptions, regulatory uses, and research needs in risk assessment are considered in this two-part volume. The first part, Use of Maximum Tolerated Dose in Animal Bioassays for Carcinogenicity, focuses on whether the maximum tolerated dose should continue to be used in carcinogenesis bioassays. The committee considers several options for modifying current bioassay procedures. The second part, Two-Stage Models of Carcinogenesis, stems from efforts to identify improved means of cancer risk assessment that have resulted in the development of a mathematical dose-response model based on a paradigm for the biologic phenomena thought to be associated with carcinogenesis.

Download or read book Multivariate Statistical Machine Learning Methods for Genomic Prediction written by Osval Antonio Montesinos López and published by Springer Nature. This book was released on 2022-02-14 with total page 707 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license This open access book brings together the latest genome base prediction models currently being used by statisticians, breeders and data scientists. It provides an accessible way to understand the theory behind each statistical learning tool, the required pre-processing, the basics of model building, how to train statistical learning methods, the basic R scripts needed to implement each statistical learning tool, and the output of each tool. To do so, for each tool the book provides background theory, some elements of the R statistical software for its implementation, the conceptual underpinnings, and at least two illustrative examples with data from real-world genomic selection experiments. Lastly, worked-out examples help readers check their own comprehension.The book will greatly appeal to readers in plant (and animal) breeding, geneticists and statisticians, as it provides in a very accessible way the necessary theory, the appropriate R code, and illustrative examples for a complete understanding of each statistical learning tool. In addition, it weighs the advantages and disadvantages of each tool.

Download or read book An Update on Research Issues in the Assessment of Birth Settings written by National Research Council and published by National Academies Press. This book was released on 2013-09-23 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: More than 30 years ago, the Institute of Medicine (IOM) and the National Research Council (NRC) convened a committee to determine methodologies and research needed to evaluate childbirth settings in the United States. The committee members reported their findings and recommendations in a consensus report, Research Issues in the Assessment of Birth Settings (IOM and NRC, 1982). An Update on Research Issues in the Assessment of Birth Settings is the summary of a workshop convened in March, 2013, to review updates to the 1982 report. Health care providers, researchers, government officials, and other experts from midwifery, nursing, obstetric medicine, neonatal medicine, public health, social science, and related fields presented and discussed research findings that advance our understanding of the effects of maternal care services in different birth settings on labor, clinical and other birth procedures, and birth outcomes. These settings include conventional hospital labor and delivery wards, birth centers, and home births. This report identifies datasets and relevant research literature that may inform a future ad hoc consensus study to address these concerns.

Download or read book Risk Analysis written by Terje Aven and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 207 pages. Available in PDF, EPUB and Kindle. Book excerpt: Everyday we face decisions that carry an element of risk anduncertainty. The ability to analyze, predict, and prepare for thelevel of risk entailed by these decisions is, therefore, one of themost constant and vital skills needed for analysts, scientists andmanagers. Risk analysis can be defined as a systematic use of informationto identify hazards, threats and opportunities, as well as theircauses and consequences, and then express risk. In order tosuccessfully develop such a systematic use of information, thoseanalyzing the risk need to understand the fundamental concepts ofrisk analysis and be proficient in a variety of methods andtechniques. Risk Analysis adopts a practical, predictiveapproach and guides the reader through a number ofapplications. Risk Analysis: Provides an accessible and concise guide to performing riskanalysis in a wide variety of fields, with minimal prior knowledgerequired. Adopts a broad perspective on risk, with focus on predictionsand highlighting uncertainties beyond expected values andprobabilities, allowing a more flexible approach than traditionalstatistical analysis. Acknowledges that expected values and probabilities couldproduce poor predictions - surprises may occur. Emphasizes the planning and use of risk analyses, rather thanjust the risk analysis methods and techniques, including thestatistical analysis tools. Features many real-life case studies from a variety ofapplications and practical industry problems, including areas suchas security, business and economy, transport, oil & gas and ICT(Information and Communication Technology). Forms an ideal companion volume to Aven’s previous Wileytext Foundations of Risk Analysis. Professor Aven’s previous book Foundations of RiskAnalysis presented and discussed several risk analysisapproaches and recommended a predictive approach. This new textexpands upon this predictive approach, exploring further the riskanalysis principles, concepts, methods and models in an appliedformat. This book provides a useful and practical guide todecision-making, aimed at professionals within the risk analysisand risk management field.