Download or read book Retinal and Optic Nerve Stem Cell Surgery written by Jeffrey N. Weiss and published by Springer Nature. This book was released on 2020-11-19 with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a concise how-to of successfully treating previously deemed "untreatable" retinal and optic nerve conditions with stem cell therapies. Based on the results of 11 years of experience treating approximately 600 patients, this text will serve as a template for others to develop similar stem cell based treatments in their specialty. Author, Jeffrey N. Weiss, MD is specifically poised to offer dependable insight on stem cell surgery for both the retina and the optic nerve, having performed the first retinal stem cell surgery in 2010, with Institutional Review Board (IRB) approved studies that are registered with the National Institute of Health (NIH), and listed on ClinicalTrials.gov. Featuring all original work from Dr. Jeffrey Weiss's specialization in stem cell ophthalmology, this book is primarily written for ophthalmologists, but structured so that specialists across disciplines can take the model presented and create their own studies and clinical trials using stem cell therapies.

Download or read book Patient s Guide to Retinal and Optic Nerve Stem Cell Surgery written by Jeffrey N. Weiss, M.d. and published by CreateSpace. This book was released on 2014-01-27 with total page 54 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book was written to educate and guide patients wishing to learn about retinal and optic nerve stem cell surgery.

Download or read book Ocular Neuroprotection written by Leonard A. Levin and published by CRC Press. This book was released on 2003-07-15 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many retinal and optic nerve disorders have no effective therapy, or are treated incompletely and with considerable side effects. Recent advances have suggested the significant benefits associated with neuroprotection - that is, when treatment strategies are directed to photoreceptors, retinal ganglion cells, or other neural targets. Enter Ocular N

Download or read book Clinical Trials in Optic Nerve Disease Treatment written by Jeffrey N. Weiss and published by Springer. This book was released on 2024-08-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compendium of the worldwide ocular stem cell, gene therapy, and other studies treating Optic Nerve Disease that are registered with Clinicaltrials.gov. The study and the Clinical Trial number is provided in order to make it easier for the reader to obtain further information. The book contains an introduction to Optic Nerve Disease as well as a summary of common optic nerve conditions. Clinical Trials in Optic Nerve Disease Treatment is a valuable resource for ophthalmologists, optometrists, other physicians, and researchers.

Download or read book Ocular Stem Cell Studies written by Jeffrey N. Weiss and published by Springer. This book was released on 2024-08-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compendium of the worldwide ocular stem cell studies registered with clinicaltrials.gov. The study title is provided, along with the country of origin and the clinical trial number in order to make it easier for the reader to locate the study and obtain further information. An analysis of the type of stem cell utilized and study support is also provided. The final section deals with issues encountered by the stem cell researchers. Ocular Stem Cell Studies: A Comprehensive Overview of Global Clinical Trials is a valuable resource for ophthalmologists, optometrists, other physicians, and researchers.

Download or read book Neurologic Stem Cell Surgery written by Jeffrey N. Weiss and published by Springer Nature. This book was released on 2021-05-04 with total page 119 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a concise how-to of successfully treating previously poorly or untreatable neurologic conditions with stem cell therapies. The text examines the IRB approved protocols of NEST (Neurologic Bone Marrow Derived Stem Cell Treatment Study), SCiExVr (Stem Cell Spinal Cord Injury Exoskeleton and Virtual Reality Treatment Study), and ACIST (Alzheimer’s and Cognitive Impairment Stem Cell Treatment Study). The discussion focuses on the protocols and informed consents and may be used as a template for specialists to develop clinical trials utilizing stem cell based therapy. Other potential noninvasive treatments for brain injury are also discussed. Neurologic Stem Cell Surgery, the sister text to the recently published Retinal and Optic Nerve Stem Cell Surgery, is an invaluable reference for all physicians with an interest in the development of stem cell based treatments.

Download or read book Retinal Degenerative Diseases written by Matthew M. LaVail and published by Springer Science & Business Media. This book was released on 2011-12-21 with total page 867 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will contain the proceedings of the XIV International Symposium on Retinal Degeneration (RD2010), held July 13-17, 2010, in Mont-Tremblant, Quebec, Canada. The volume will present representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy.

Download or read book Cell Based Therapy for Retinal Degenerative Disease written by R.P. Casaroli-Marano and published by Karger Medical and Scientific Publishers. This book was released on 2014-04-22 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this volume, some of the leading authorities present their exploration of applications of stem cell therapy to the treatment of major causes of blindness, including degenerative diseases and glaucoma. The diagnostic approach to patients, general concepts of cell-based therapy, immunological considerations, approaches to cell delivery (including engineered scaffolds), combined cell and gene therapy, nanomedicine applications to cell therapy and regulatory issues pertaining to manufacture and production are all considered in detail. The book serves as an excellent introduction to a field that is now entering early-stage clinical trials and promises to operate at the leading edge of regenerative medicine. Retina specialists, general ophthalmologists as well as researchers will find here a wealth of information on the translational aspects of cell-based therapies. Further, business executives and students interested in understanding the potential applications of stem cell therapy to retinal degenerative disease and glaucoma will also find this book informative reading.

Download or read book The Eye written by Eman E. Taher and published by Elsevier. This book was released on 2023-03-31 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Eye, Volume Four, the latest release in the Stem Cell Innovation in Health and Disease series, addresses the recent data accumulated on the potential applications of stem cells to treat eye diseases. This volume highlights the recent development of cutting-edge in vitro and in vivo research tools and approaches, including human and murine organoid cultures, genetic editing in vitro and in vivo, human iPSC models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure eye diseases. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors in the field. This is a timely and fascinating collection of information and new discoveries that provides a contemporary snapshot album on the fast-moving field of regenerative medicine and stem cell therapeutics. Provides cutting-edge research to understand stem cell functions used in disease treatments of the eye Develops processes to bring stem cells from bench to bedside Includes up-to-date references on stem cell biology and function in common eye diseases and disorders

Download or read book Orthopedic Stem Cell Surgery written by Jeffrey N. Weiss and published by Springer Nature. This book was released on 2021-06-26 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a concise guide that provides an easy to follow template for other physicians to develop similar stem cell based treatments within their specialty. It identifies and summarizes the current world-wide orthopedic stem cell trials. Organized into three sections, Orthopedic Stem Cell Surgery presents clinical studies that examine the procedures for setting up and implementing stem cell surgery within the specialty of orthopedics. Chapters maintain an accessible narrative while also addressing complex studies related to orthopedic stem cell surgery. A sister text to the recently published, Retinal and Optic Nerve Stem Cell Surgery, and Neurologic Stem Cell Surgery this expertly written book examines critical Institutional Review Board (IRB) approved studies.

Download or read book Cellular Therapies for Retinal Disease written by Steven D. Schwartz and published by Springer. This book was released on 2017-06-20 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book familiarizes the reader with the current landscape of cell-based therapies for the treatment of retinal disease, including diseases that affect the choriocapillaris, retinal pigment epithelium, photoreceptors, and retinal ganglion cells. Instead of utilizing a disease-centric approach to the topic, this book—edited by two world-renowned stem cell scientists—focuses on strategies for developing and transplanting the cells. This includes the creation of replacement cells, cell-based neuroprotection, and in vitro disease modeling and testing. The final chapters briefly review parallel approaches that do not directly utilize cellular transplantation. The use of cellular transplantation to treat retinal disease has recently become a viable and exciting therapeutic approach. The visibility of the retina and its laminar cellular architecture render it an ideal organ for the development of surgically delivered cellular therapies. Having an in-depth understanding of the current state of cell therapy for the eye is an essential first step toward utilizing similar approaches in other organs. Ophthalmologists, translational clinician-scientists, stem cell scientists, and researchers interested in eye disease will find Cellular Therapies for Retinal Disease: A Strategic Approach essential reading and it is also suitable for workshops or courses at the undergraduate or Ph.D. level.

Download or read book Why Is Grandma Still Blind written by Jeffrey Neill Weiss and published by . This book was released on 2017-09-15 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stem cells were discovered in 1981. Why, after so many years, has little been accomplished? Dr. Weiss, the Principal Investigator of the Stem Cell Ophthalmology Treatment Studies, the largest Institutional Review Board approved retina and optic nerve stem cell studies in the world, explains in straightforward language, why the promise of stem cells has not been kept.

Download or read book Regenerative Biology of the Eye written by Alice Pébay and published by Springer. This book was released on 2014-05-23 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is a comprehensive look at the current knowledge on stem cell application for vision loss, showcasing different types of stem cells (adult, embryonic, iPSCs) for diseases of the front and the back of the eye. It also highlights data obtained in various models from fish to human, as well as from the bionic eye project for vision regeneration. This volume in the Stem Cell Biology and Regenerative Medicine series is essential reading for stem cell biologists, ophthalmologists, advanced and graduate students, in addition to academics and medical staff who work in these disciplines.

Download or read book Cell Based Therapy for Degenerative Retinal Disease written by Marco A. Zarbin and published by Springer. This book was released on 2019-03-01 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses why specific diseases are being targeted for cell-based retinal therapy, what evidence exists that justifies optimism for this approach, and what challenges must be managed in order to bring this technology from the laboratory into routine clinical practice. There are a number of unanswered questions (e.g., surgical approach to cell delivery, management of immune response, optimum cell type to transplant) that very likely are not going to be answered until human trials are undertaken, but there is a certain amount of “de-risking” that can be done with preclinical experimentation. This book is essential reading for scientists, clinicians, and advanced students in stem cell research, cell biology, and ophthalmology.

Download or read book Neuroprotection and Neuroregeneration for Retinal Diseases written by Toru Nakazawa and published by Springer. This book was released on 2014-07-23 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the latest findings on neuroprotection and neuroregeneration as potential therapeutic strategies for various eye diseases, namely, glaucoma, age-related macular degeneration (AMD), retinal detachment, and retinitis pigmentosa. Glaucoma is one of the main causes of blindness throughout the world, and other diseases such as AMD and retinitis pigmentosa also lead to loss of vision. All these conditions are characterized by degeneration of specific retinal cell types, making it essential to establish treatments to protect retinal neurons and the optic nerve. With that aim in mind, this book explains the mechanisms underlying aforementioned diseases and their experimental models. The novel strategy proposals for the treatment of retinal diseases based on the concept of neuroprotection are also discussed in the main body of the text, while the section on regenerative research discusses optic nerve regeneration, endothelial progenitor cells, and iPS cells. This book is recommended as a professional reference work for all doctors and trainees in the field of ophthalmology who are interested in neuroprotective and neuroregenerative treatments.

Download or read book Stem Cell Surgery Trials in Heart Failure and Diabetes written by Jeffrey N. Weiss and published by Springer Nature. This book was released on 2022-03-23 with total page 164 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the application of stem cell surgery for diabetes and heart failure. Organized into two sections, the first identifies and summarizes the current worldwide stem cell trials for heart failure. Subsequent chapters in part two analyze the current worldwide stem cell trials in patients with Diabetes Mellitus. Both sections utilize studies that include non-expanded stem cells; each study is grouped by stem cell type and geographic location. Stem Cell Surgery Trials in Diabetes and Heart Failure is a comprehensive, convenient reference for cardiologists, endocrinologists, internists, and family physicians.

Download or read book Human Amniotic Membrane Basic Science And Clinical Application written by Nazly Hilmy and published by World Scientific. This book was released on 2017-08-23 with total page 380 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a comprehensive guide for all tissue bank operators to screen, procure and process amniotic membrane for clinical application.The amnion comes close to being the ideal biological membrane or dressing — readily available, inexpensive to procure and process. Its basic science is discussed in detail — anatomy, biological and biomechanical properties.It can be procured from the placenta in normal vaginal deliveries and from Caesarean Sections. Processing is by freeze-drying or by air-drying process with sterilisation using gamma irradiation.The product has low antigenicity, has anti-microbial properties with ability to enhance epithelisation with marked relief of pain. It is useful as a dressing for wounds — flap wounds, burn wounds, injury wounds, diabetic ulcers, leprous ulcers and post-surgery wounds and post-radiation wounds. It is also used as a biological scaffold for cells in tissue engineering. Its ophthalmic applications include treatment of corneal ulcers and conjunctival tumours. Oral uses include gingiva depigmentation and periodontal regeneration.