Download or read book Redirection of Th1 and Th2 Responses written by Robert L. Coffman and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt: The two major subsets of CD4+ helper T cells, designated Th1 and Th2, have quite different patterns of cytokine production and, as a consequence, have very different roles in immune responses. The articles in this volume review both basic and clinical studies of T cell heterogeneity, including: the mechanisms by which Th1 and Th2 cells develop and maintain their differences in cytokine production; the different roles of Th1 and Th2 cells in allergy, autoimmunity and infectious diseases; the prospects and strategies for therapeutic manipulation of Th1 and Th2 cells; and the control of Th1 and Th2 responses by regulatory T cell subsets. The volume should give the reader a view of the development and function of Th1 and Th2 cells and the attempts to treat immunological diseases with therapies directed towards altering the Th1/Th2 balance.
Download or read book Scenarios and Responses to Future Deep Oil Spills written by Steven A. Murawski and published by Springer. This book was released on 2019-07-04 with total page 542 pages. Available in PDF, EPUB and Kindle. Book excerpt: It has often been said that generals prepare for the next war by re-fighting the last. The Deepwater Horizon (DWH) oil spill was unlike any previous – an underwater well blowout 1,500 meters deep. Much has been learned in the wake of DWH and these lessons should in turn be applied to both similar oil spill scenarios and those arising from “frontier” explorations by the marine oil industry. The next deep oil well blowout may be at 3,000 meters or even deeper. This volume summarizes regional (Gulf of Mexico) and global megatrends in marine oil exploration and production. Research in a number of key areas including the behavior of oil and gas under extreme pressure, impacts on biological resources of the deep sea, and the fate of oil and gas released in spills is synthesized. A number of deep oil spills are simulated with detailed computer models, and the likely effects of the spills and potential mitigation measures used to combat them are compared. Recommended changes in policies governing marine oil exploration and development are proposed, as well as additional research to close critical and emerging knowledge gaps. This volume synthesizes state-of-the-art research in deep oil spill behavior and response. It is thus relevant for government and industry oil spill responders, policy formulators and implementers, and academics and students desiring an in-depth and balanced overview of key issues and uncertainties surrounding the quest for deep oil and potential impacts on the environment.
Download or read book Differential Radiosensitivity of First and Second set Responses to Allogenic and Xenogenic Skin Grafts in Sublethally Irradiated Mice written by M. L. Tyan and published by . This book was released on 1963 with total page 22 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Factors Determining Long Term Anti Tumor Responses to Immune Checkpoint Blockade Therapy written by Alison Taylor and published by Frontiers Media SA. This book was released on 2023-01-31 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Platelets and Immune Responses During Thromboinflammation written by Mirta Schattner and published by Frontiers Media SA. This book was released on 2020-07-09 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Approaches to Blocking the Immune Response to Gene Transfer with Viral Vectors written by Katherine High and published by Frontiers E-books. This book was released on with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viral vectors are superior tools for gene therapy and as a genetic vaccine platform because viruses have evolved to efficiently infect and transfer their genomes to cells. Several impressive successes in viral vector-based gene therapies have been reported in humans, including restoration of vision in patients with Leber’s congenital amaurosis by retinal gene transfer and cures for severe immune deficiencies by gene transfer to hematopoietic stem cells. However, the mammalian immune system has evolved in parallel to fend off invading pathogens such as viruses. Innate and antigen-specific adaptive immune responses against viral vectors and therapeutic transgene products pose serious hurdles for successful gene therapy. Pre-existing immunity in humans, resulting from prior exposure to the parent virus that forms the basis for the gene transfer vehicle may be derived from, often prevents efficient gene transfer. This problem also reduces our ability to use certain vectors for genetic vaccination or in anti-cancer therapy. For these reasons, the gene transfer community has been extensively studying the mechanisms of immune responses against viral vectors and has started to develop strategies and protocols to block or circumvent such responses. Choice, design and engineering of a vector as well as the route of administration/target tissue can be optimized/ altered to minimize immune responses or evade pre-existing immunity. Immune suppression and modulation strategies are being developed in order to minimize inflammation, prevent antibody or T cell responses against vectors, and to promote tolerance to therapeutic gene products. Combinations of these approaches will likely facilitate clinical applications of gene therapy for many target diseases and also aid in vaccine development.
Download or read book Making Meaning written by Developmental Studies Center (Oakland, Calif.) and published by . This book was released on 2003-07-30 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Is designed to help the teacher make informed instructional decisions and track students' reading comprehension and social development as they teach the Making Meaning lesson. Consumable.
Download or read book The Th2 Type Immune Response in Health and Disease written by William C. Gause and published by Springer. This book was released on 2015-12-08 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: The type 2 immune response that develops during infectious disease has undergone major paradigm shifts in the last several years as new cell types and pathways have been identified. It is now clear that the type 2 immune response, characterized by elevations in specific cytokines, including IL-4, IL-5 and IL-13, is associated with helminth infections in both humans and mice. This response is complex and includes effector functions that mediate resistance, contributing to expulsion and in some cases destruction, of the parasite. But just as importantly, the type 2 immune response can also mediate tolerance mechanisms, which can mitigate tissue injury as these large multicellular parasites transit through vital organs. The tolerance mechanisms include both tissue repair and immune regulatory effects. These latter aspects of the helminth-induced type 2 immune response are increasingly recognized as a potential resource that can be mined for the development of novel immunotherapies that may enhance wound healing, control of autoimmune and inflammatory diseases and regulation of metabolic homeostasis. In this book, leading researchers in this exciting and dynamic field discuss the latest findings and emerging concepts, providing an intellectual framework that can be used as a basis for new discoveries and potentially new treatments for diseases associated with inflammation.
Download or read book Variability of Annoyance Response Due to Aircraft Noise written by Thomas K. Dempsey and published by . This book was released on 1979 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Resilience and Vulnerability Factors in Response to Stress written by Chantal Martin-Soelch and published by Frontiers Media SA. This book was released on 2020-01-31 with total page 220 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Response to Intervention written by William N. Bender and published by Corwin Press. This book was released on 2007-04-05 with total page 161 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discover a resource that shows teachers how to implement RTI in the classroom! This practical guide helps educators understand the tiers of the Response to Intervention (RTI) process, as well as how to implement interventions and utilize the results to modify existing instruction for students in the classroom. With vignettes, examples, and reproducible forms based on the problem-solving and standards-based approaches to RTI, this accessible handbook gives teachers the tools to: Document the existence or nonexistence of a learning disability Monitor individual student progress Plan specific follow-up interventions based on a learner's needs Implement strategies to support students' success
Download or read book Response to Disaster written by Richard Gist and published by Routledge. This book was released on 2013-11-12 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychological service in the wake of cataclysmic life events has emerged as a prominent and visible component of social response. This has generated a bandwagon of potential service providers, service approaches, and service venues. Where once help was scarce, it has become plentiful enough to engender its own set of conflicts and contradictions along with its intended solace and aid. Response to Disaster reconciles the technical, theoretical, and applied interests represented in these various populations and provides a contemporary treatment that can help define the directions of their increasing interaction.
Download or read book Call and Response written by Rob Carney and published by . This book was released on 2021-02-15 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt: Poetry. "Rob Carney is tuned to some amazing frequency--it comes from 500 North and Morton, it comes from beyond, it comes from when we were wooded slopes--but he listens and returns with these poems, thrumming with 'lifeblood,' these songs which throw down and call out (see 'Poetic Justice'), which are often rich with praise but never falsify. Sure, one might want to 'lovetalk' nature but nature will always kick our ass. It's always there, underneath us, 'with teeth.' I find this book both serious and joyful. CALL AND RESPONSE is such a good journey."--Kate Northrop
Download or read book Stimulus Response Compatibility written by R.W. Proctor and published by Elsevier. This book was released on 1989-12-18 with total page 505 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stimulus-response compatibility refers to the finding that certain mappings of stimuli to responses produce faster and more accurate responding than do others. The present volume surveys compatibility research which falls into four broad categories: (a) mental representation and coding (b) neurophysiological mechanisms (c) motor performance (d) human factors applications. The major findings and models within each of the categories are summarized, and an integrated perspective is provided. The research indicates that compatibility effects reflect basic cognitive processes that bear on a range of issues in cognitive science and that have applied implications for human factors specialists.
Download or read book Autophagy Infection and the Immune Response written by William T. Jackson and published by John Wiley & Sons. This book was released on 2014-12-03 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: The relationship between infection and immunity and autophagy, a pathway of cellular homeostasis and stress response, has been a rapidly growing field of study over the last decade. While some cellular processes are pro- or anti-infection, autophagy has been proven to be both: a part of the innate immune response against some microbes, and a cellular pathway subverted by some pathogens to promote their own replication. Autophagy, Infection, and the Immune Response provides a unified overview of the roles of cellular autophagy during microbial infection. Introductory chapters ground the reader by delineating the autophagic pathway from a cellular perspective, and by listing assays available for measuring autophagy. Subsequent chapters address virus interactions with autophagy machinery, the various roles of autophagy parasitic infection, and interactions of bacteria with the autophagic pathway. Concluding chapters explore the relationships of autophagy to systemic immune responses, including antigen presentation, ER stress, and production of IFN-gamma. Designed as a resource for those interested in initiating studies on the relationship between autophagy and infection or immunity, Autophagy, Infection, and the Immune Response combines practical state-of the art technique descriptions with an overview of the wide variety of known interactions between pathogens and the autophagic pathway.
Download or read book Collaborative Response written by Kurtis Hewson and published by Corwin Press. This book was released on 2022-02-27 with total page 273 pages. Available in PDF, EPUB and Kindle. Book excerpt: A school-wide model for addressing individual needs The greatest goal of education is to ensure equity while enhancing learning and academic success for all students. And yet, it is impossible for one teacher to meet the extensive needs of all students in his or her classroom. The traditional schooling model cannot provide for this complexity and leaves educators perplexed. The solution is a collaborative approach where “every child deserves a team” to surround them with supports that recognize their strengths and challenges. Collaborative Response offers a school-wide model for addressing students’ individual needs. The three fundamental components of the model are: collaborative structures and processes; data and evidence; and continuum of supports. In this book, readers will find: Entry points for beginning this work Potential pitfalls of the approach Case studies from schools that have adopted the model Access to a website with tools, templates, case studies, and more With a focus on quality classroom instruction, this book shares examples from schools and districts that have transformed how they respond to the needs of all learners.
Download or read book Responses of Midbrain Cells in Macaca Mulatta Related to Transmission of Impulses Associated with Noxious Stimulation written by James Alexander McMillan and published by . This book was released on 1970 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
