Download or read book Rejection of Allogeneic Skin Grafts and Production of Isohemagglutinins by Sensitized Mice After Sublethal Irradiation written by M. L. Tyan and published by . This book was released on 1965 with total page 10 pages. Available in PDF, EPUB and Kindle. Book excerpt: Male B6D2F1 mice were sensitized by the following means: (1) an allogeneic (A/HeJ) skin graft; (2) three s.c. injections of A/HeJ spleen cells in Freund's complete adjuvant; or (3) three i.p. 'njections of A/HeJ spleen cells. One week after the last injection, mice from each group received 670 rad whole-body X radiation. Sera were obtained frequently for hemagglutinin assay, and the mice were grafted with A/HeJ skin 30 days or 61 days after irradiation. In all groups the homograft response was significantly impaired 30 and 61 days after irradiation; however, in groups (1) and (2) normal secondary hemagglutinin responses were noted. This asynchronous recovery of the hemagglutinin and homograft responses suggested that distinct cell populations were responsible for these two manifestations of immunologic reactivity. (Author).
Download or read book Technical Abstract Bulletin written by and published by . This book was released on with total page 780 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Journal of Immunology written by and published by . This book was released on 1965 with total page 614 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1966 with total page 1542 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Radiation and infection written by Richard D. Stoner and published by . This book was released on 1967 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Rejection and Tolerance written by J.-L. Touraine and published by Springer Science & Business Media. This book was released on 1993-12-31 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Proceedings of the 25th Conference on Transplantation and Clinical Immunology 24--26 May 1993
Download or read book Clinical Xenotransplantation written by David K. C. Cooper and published by Springer Nature. This book was released on 2020-09-08 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title provides an illuminating examination of the current state of xenotransplantation – grafting or transplanting organs or tissues between members of different species – and how it might move forward into the clinic. To be sure, this is a critical topic, as a major problem that remains worldwide is an inadequate supply of organs from deceased human donors, severely limiting the number of organ transplants that can be performed each year. Based on presentations given at a major conference on xenotransplantation, this title includes important views from many leading experts who were invited to present their data and opinions on how xenotransplantation can advance into the clinic. Attention was concentrated on pig kidney and heart transplantation as it is in regard to these organs that most progress has been made. Collectively, these chapters effectively highlight the many advantages of xenotransplantation to patients with end-stage organ failure, thereby encouraging the mapping of a concrete pathway to clinical xenotransplantation. The book is organized across 22 chapters, beginning with background information on clinical and experimental xenotransplantation. Following this are discussions addressing how pigs can be genetically engineered for their organs to be resistant to the human immune response through deletion of pig xenoantigens, and the insertion of ‘protective’ human transgenes. Subsequent chapters analyze complications that arise in practice, comparing allotransplant and xenotransplant rejection. The selection of the ideal patients for the first clinical trials is discussed. Finally, the book concludes with an analysis on the regulatory, economic, and social aspects of this research, including FDA perspectives and the sensitive, psychosocial factors regarding allotransplantation and xenotransplantation. A major and timely addition to the literature, Clinical Xenotransplantation will be of great interest to all researchers, physicians, and academics from other disciplines with an interest in xenotransplantation.
Download or read book Immunobiology of the Head and Neck written by J.F. Poliquin and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work reviews the basic concepts of immunology and introduces the reader to the latest findings on immunological aspects of diseases of the head and neck. In the past two decades, there has been an explosion of new knowledge in immunology. The contributors to this volume, all of whom have been active in clinical and basic research, describe how recent discoveries in immunology play an increasingly vital role in the understanding and care of patients with head and neck diseases. An important teaching tool for the resident in training and a valuable reference work for physicians in practice, this book will be of special interest to otolaryngologist-head and neck surgeons, surgical oncologists, pediatricians, allergists, rheumatologists and edu cators desiring an advanced text in the field. Jacques F. Poliquin, MD Allen F. Ryan, PhD Jeffrey P. Harris, MD, PhD INTRODUCTION Immunology has been traced back at least to 1000 AD. when the Chinese discovered that the inhalation of smallpox crusts had some value in prevention of the disease. However, immunology as a science has developed almost entirely within the last 100 years.
Download or read book Textbook of Microbiology written by R. Ananthanarayan and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Abstracts of microbiology and hygiene written by and published by . This book was released on 1968 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Textbook of Immunology written by SK Mohanty and published by JP Medical Ltd. This book was released on 2013-11-30 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new edition has been fully revised to provide the most up to date information in the field of immunology. Beginning with a brief history of the subject, the following chapters cover all aspects of immunology, from basic immunity and antigens, to immunodeficiency disorders including HIV, tumour immunology, and transplantation immunology. This concise second edition is highly illustrated with detailed graphics, colour diagrams, charts and tables, and each chapter features study questions and suggestions for further reading. Key points Fully revised, second edition, providing latest information on complete field of immunology Highly illustrated with graphics, diagrams, charts and tables Study questions and further reading suggestions included in each chapter Previous edition published in 2007
Download or read book Clinical Organ Transplantation written by Roy Yorke Calne and published by Wiley-Blackwell. This book was released on 1971 with total page 562 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book A History of Transplantation Immunology written by Leslie Brent and published by Academic Press. This book was released on 1996-11-18 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: Those entering the field of transplantation are frequently unaware of the topics historical roots and even of the background on which modern discoveries in tolerance, histocompabatibility antigens, and xenotransplantation are based. A History of Transplantation Immunology is an account, written by one of the founding fathers of the field, of how tissue and organ transplantation has become one of the most successful branches of late 20th century medicine. The book helps place the work of contemporary scientists into its proper context and makes fascinating reading for immunologists in all stages of their career. Describes landmarks in immunology and places them in historical context Beautifully written by one of the founding fathers of the field Portrays the surprising history of events in a colorful and readable manner Contains biographical sketches of some of the pioneers Illustrates the development of key ideas in immunology--tolerance, graft rejection, and transplantation Foreword by Ray Owen
Download or read book HLA and Disease Associations written by J.L. Tiwari and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human leukocyte antigen (HLA) or tissue types are the products of a rapidly developing field of knowledge within the last 20 years. In the early stages of the research many investigators suspected the existence of a complex series of transplantation antigens, but it was widely believed that these antigens would not be well-defined even in this century. Yet in the last two decades as many as 124 different HLA antigens determined by at least 7 very closely linked genes located on the short arm of chromosome 6 have been identified and subsequently agreed upon by an international nomenclature committee. 1 Extensive international collaboration fueled by the potential clinical application of these antigens to clinical transplantation has advanced the field rapidly. There were nine inter national histocompatibility workshops held during this period. Although iden tification of HLA antigens was of primary clinical importance in transplantation 2 and of great basic interest in human genetics and anthropology, a rather un expected bonus has been the determination that HLA antigens are associated with disease susceptibility to a greater extent than any other known genetic marker in man. In the past, many genetic polymorphisms have been suspected to be associated with diseases. The most extensively studied markers are blood groups, enzymes, and serum proteins. A comprehensive account of published studies, totalling approximately 1,000, of these markers is available in a book by Mourant et al.
Download or read book Thoracic Transplantation written by Sara Shumway and published by Wiley-Blackwell. This book was released on 1995-07-12 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a definitive look at heart, lung, and heart-lung transplantation. It includes historical background on these procedures, and discusses the immunological basis of transplantation, organ preservation, donor procurement, pre-transplant recipient management, operative techniques, post-operative care, pathology, special considerations (cystic fibrosis, etc.) lung transplantation (results and complications) and future prospects, including a chapter on xenotransplantation by Columbia's Keith Reemtsma.
Download or read book Textbook Of Practical Microbiology written by Subhash Chandra Parija and published by . This book was released on 2007-03-01 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Intent Of The Book Is To Provide Recent Information & Explain In Detail The Routine Diagnostic Methods Performed In A Microbiology Laboratory. Every Effort Has Been Made To Incorporate All Aspects Of Practical Microbiology. This Book Consists Of 151 Learning Units. Each Units Contains Many Practical Exercise. The Book Is Profusely Illustrated With Diagrams & Photomicrographs Both Black & White & Color..
Download or read book Alphaherpesviruses written by Sandra Knowles Weller and published by Caister Academic Press Limited. This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Alphaherpesviruses are a fascinating group of DNA viruses that includes important human pathogens such as herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV): the causative agents of cold sores, genital ulcerous disease, and chickenpox/shingles, respectively. A key attribute of these viruses is their ability to establish lifelong latent infection in the peripheral nervous system of the host. Such persistence requires subversion of the host's immune system and intrinsic antiviral defense mechanisms. Understanding the mechanisms of the immune evasion and what triggers viral reactivation is a major challenge for today's researchers. This has prompted enormous research efforts into understanding the molecular and cellular biology of these viruses. This up-to-date and comprehensive volume aims to distill the most important research in this area providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections.
