Download or read book Reinventing Discovery written by Michael Nielsen and published by Princeton University Press. This book was released on 2020-04-07 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Reinventing Discovery argues that we are in the early days of the most dramatic change in how science is done in more than 300 years. This change is being driven by new online tools, which are transforming and radically accelerating scientific discovery"--
Download or read book Modern CNS Drug Discovery written by Rudy Schreiber and published by Springer Nature. This book was released on 2021-06-17 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system. It guides the reader through all essential steps, from finding an innovative idea, to the registration of a new drug. Divided into four sections, the book starts by presenting a broad perspective on current approaches in central nervous system (CNS) drug discovery. The second section addresses the generation of ideas for the identification of targets and novel treatment strategies; covers core functions in early discovery, and provides an example of a novel treatment paradigm: brain stimulation. The third section highlights strategies and technologies in translational CNS drug discovery. In an effort to bridge the gap between discovery and clinical development, it also covers brain imaging, EEG and cognitive testing approaches. The fourth section extensively discusses the clinical phase of drug development, covering the basics of early clinical testing for psychopharmacological drugs. The book’s final chapter addresses the registration for newly developed drugs. Written by experts from academia and industry, the book covers important basics and best practices, as well as recent developments in drug discovery. Offering in-depth insights into the world of drug development, it represents essential reading for early researchers who want to prepare for a career in drug discovery in academia or industry.
Download or read book Science Set Free written by Rupert Sheldrake and published by Deepak Chopra. This book was released on 2013-09-03 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: The bestselling author of Dogs That Know When Their Owners Are Coming Home offers an intriguing new assessment of modern day science that will radically change the way we view what is possible. In Science Set Free (originally published to acclaim in the UK as The Science Delusion), Dr. Rupert Sheldrake, one of the world's most innovative scientists, shows the ways in which science is being constricted by assumptions that have, over the years, hardened into dogmas. Such dogmas are not only limiting, but dangerous for the future of humanity. According to these principles, all of reality is material or physical; the world is a machine, made up of inanimate matter; nature is purposeless; consciousness is nothing but the physical activity of the brain; free will is an illusion; God exists only as an idea in human minds, imprisoned within our skulls. But should science be a belief-system, or a method of enquiry? Sheldrake shows that the materialist ideology is moribund; under its sway, increasingly expensive research is reaping diminishing returns while societies around the world are paying the price. In the skeptical spirit of true science, Sheldrake turns the ten fundamental dogmas of materialism into exciting questions, and shows how all of them open up startling new possibilities for discovery. Science Set Free will radically change your view of what is real and what is possible.
Download or read book Reinventing The Future written by Thomas A. Bass and published by Addison Wesley Publishing Company. This book was released on 1994 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The author of The Eudaemonic Pie now reveals the inspiration, motivations, and aspirations of the world's greatest scientists. The scientists interviewed in this collection have changed the rules of the game--altered our perception of reality and the language used to describe it.
Download or read book The Creativity Crisis written by Roberta B. Ness and published by Oxford University Press, USA. This book was released on 2015 with total page 297 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Creativity Crisis excavates the root causes of America's innovation slow-down, showing why revolutionary insights are no longer chased by young talent. Economically and socially, caution has overtaken creation. This book is ultimately a roadmap for reinvigorating innovation within the system of science"--
Download or read book Reinventing Knowledge From Alexandria to the Internet written by Ian F. McNeely and published by W. W. Norton & Company. This book was released on 2009-09-08 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: History.
Download or read book Creation written by Adam Rutherford and published by Penguin. This book was released on 2013-06-13 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: What is life? Humans have been asking this question for thousands of years. But as technology has advanced and our understanding of biology has deepened, the answer has evolved. For decades, scientists have been exploring the limits of nature by modifying and manipulating DNA, cells and whole organisms to create new ones that could never have existed on their own. In Creation, science writer Adam Rutherford explains how we are now radically exceeding the boundaries of evolution and engineering entirely novel creatures—from goats that produce spider silk in their milk to bacteria that excrete diesel to genetic circuits that identify and destroy cancer cells. As strange as some of these creations may sound, this new, synthetic biology is helping scientists develop radical solutions to some of the world’s most pressing crises—from food shortages to pandemic disease to climate change—and is paving the way for inventions once relegated to science fiction. Meanwhile, these advances are shedding new light on the biggest mystery of all—how did life begin? We know that every creature on Earth came from a single cell, sparked into existence four billion years ago. And as we come closer and closer to understanding the ancient root that connects all living things, we may finally be able to achieve a second genesis—the creation of new life where none existed before. Creation takes us on a journey four billion years in the making—from the very first cell to the ground-breaking biological inventions that will shape the future of our planet.
Download or read book Reinventing Project Based Learning 2nd Edition written by Suzie Boss and published by International Society for Technology in Education. This book was released on 2014-10-21 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lead students through powerful learning experiences with Reinventing Project-Based Learning, a guide for educators, administrators and professional development specialists who want to make the shift to a more student-driven learning model. Explore proven strategies for overcoming the limitations of the traditional classroom, including a wealth of technology tools for inquiry, collaboration and global connection to support this new vision of instructional design.
Download or read book The Road to Reinvention written by Josh Linkner and published by John Wiley & Sons. This book was released on 2014-05-27 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: Companies, communities, and individuals fall for many reasons, but one of the most common—and easily avoidable—is the failure to reinvent. When people and organizations rest on prior successes rather than driving purposeful transformation, they discover too late that they have lost their market position altogether to competitors and external forces. The most successful companies, brands, and individuals make reinvention a regular part of their business strategies. Transformation demands an ongoing process of discovery and imagination, and The Road to Reinvention lays out a systematic approach for continually challenging and reinventing yourself and your business. Venture capitalist and serial entrepreneur Josh Linkner identifies six elements in any business that are ripe for reinvention and shares examples, methods, and step-by-step techniques for creating deliberate, productive disruption. Throughout The Road to Reinvention, Linkner also explores the history—the great rise, unprecedented fall, and now rebirth—of his beloved hometown, Detroit. First rising to greatness as the result of breathtaking innovation, Detroit had generations of booming growth before succumbing to apathy, atrophy, and finally bankruptcy. Now, the city is rising from the ashes and driving sustainable success through an intense focus on reinvention. Linkner brings an insider's view of this incredible story of grit, determination, and creativity, sharing his perspective on Detroit's successes and setbacks as a profound example of large-scale organizational and personal transformation. Change is inevitable. You need to decide: Will you drive that change, or be driven away by it? Will you disrupt or be disrupted? By choosing to deliberately reimagine your own status quo, you can secure a strong future for both your company and your career.
Download or read book Reinventing Yourself Today written by Sharon Ball and published by Xlibris Corporation. This book was released on 2011-04-14 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: Life is a journey and sometimes we need a roadmap to get exactly where we want to go. Reinventing Yourself Today presents a step by step program that walks you through identifying and reprogramming unconscious beliefs, self talk, and other issues that lead to the learned behaviors and habits that have created your present reality. With the help of the workbook exercises at the end of each chapter, you are led through self discovery and goal setting to create your ideal life vision and then to deal with the many obstacles in your path such as stress, poor self esteem, etc. while you bring your vision of ideal life to reality. We must always change, renew, rejuvenate ourselves; otherwise we harden. ~ Johann Wolfgang von Goethe Its never too late to be what you might have been. ~George Eliot
Download or read book Empire of Imagination written by Michael Witwer and published by Bloomsbury Publishing USA. This book was released on 2015-10-06 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first comprehensive biography of geek and gaming culture's mythic icon, Gary Gygax, and the complete story behind his invention of Dungeons & Dragons. The life story of Gary Gygax, godfather of all fantasy adventure games, has been told only in bits and pieces. Michael Witwer has written a dynamic, dramatized biography of Gygax from his childhood in Lake Geneva, Wisconsin to his untimely death in 2008. Gygax's magnum opus, Dungeons & Dragons, would explode in popularity throughout the 1970s and '80s and irreversibly alter the world of gaming. D&D is the best-known, best-selling role-playing game of all time, and it boasts an elite class of alumni--Stephen Colbert, Robin Williams, and Vin Diesel all have spoken openly about their experience with the game as teenagers, and some credit it as the workshop where their nascent imaginations were fostered. Gygax's involvement in the industry lasted long after his dramatic and involuntary departure from D&D's parent company, TSR, and his footprint can be seen in the role-playing genre he is largely responsible for creating. Through his unwavering commitment to the power of creativity, Gygax gave generations of gamers the tools to invent characters and entire worlds in their minds. Witwer has written an engaging chronicle of the life and legacy of this emperor of the imagination.
Download or read book Reinventing Hoodia written by Laura A. Foster and published by University of Washington Press. This book was released on 2017-09-18 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: Native to the Kalahari Desert, Hoodia gordonii is a succulent plant known by generations of Indigenous San peoples to have a variety of uses: to reduce hunger, increase energy, and ease breastfeeding. In the global North, it is known as a natural appetite suppressant, a former star of the booming diet industry. In Reinventing Hoodia, Laura Foster explores how the plant was reinvented through patent ownership, pharmaceutical research, the self-determination efforts of Indigenous San peoples, contractual benefit sharing, commercial development as an herbal supplement, and bioprospecting legislation. Using a feminist decolonial technoscience approach, Foster argues that although patent law is inherently racialized, gendered, and Western, it offered opportunities for Indigenous San peoples, South African scientists, and Hoodia growers to make unequal claims for belonging within the shifting politics of South Africa. This radical interdisciplinary and intersectional account of the multiple materialities of Hoodia illuminates the co-constituted connections between law, science, and the marketplace, while demonstrating how these domains value certain forms of knowledge and matter differently.
Download or read book Reinventing Bach written by Paul Elie and published by Union Books. This book was released on 2013-04-04 with total page 731 pages. Available in PDF, EPUB and Kindle. Book excerpt: Johann Sebastian Bach – celebrated pipe organist, court composer and master of sacred music – was also a technical pioneer. Working in Germany in the early eighteenth century, he invented new instruments and carried out experiments in tuning, the effects of which are still with us today. Two hundred years later, a number of extraordinary musicians have utilised the music of Bach to thrilling effect through the art of recording, furthering their own virtuosity and reinventing the composer for our time. In Reinventing Bach, Paul Elie brilliantly blends the stories of modern musicians with a polyphonic account of our most celebrated composer’ s life to create a spellbinding narrative of the changing place of music in our lives. We see the sainted organist Albert Schweitzer playing to a mobile recording unit set up at London’ s Church of All Hallows in order to spread Bach’ s organ works to the world beyond the churches, and Pablo Casals’ s Abbey Road recordings of Bach’ s cello suites transform the middle-class sitting room into a hotbed of existentialism; we watch Leopold Stokowski persuade Walt Disney to feature his own grand orchestrations of Bach in the animated classical-music movie Fantasia – which made Bach the sound of children’ s playtime and Hollywood grandeur alike – and we witness how Glenn Gould’ s Goldberg Variations made Bach the byword for postwar cool. Through the Beatles and Switched-on Bach and Gö del, Escher, Bach – through film, rock music, the Walkman, the CD and up to Yo-Yo Ma and the iPod – Elie shows us how dozens of gifted musicians searched, experimented and collaborated with one another in the service of a composer who emerged as the prototype of the spiritualised, technically savvy artist.
Download or read book The Year of Knots written by Windy Chien and published by Abrams. This book was released on 2019-09-17 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: An acclaimed artist celebrates the creative possibilities of macramé and knots in this memoir and guide featuring projects and tutorials. Every day for a year, artist Windy Chien learned to tie a new kind of knot and then shared the results on Instagram—a project that both reinvented her life and revolutionized knot art. In The Year of Knots, Chien describes how knot-making led her on a path of discovery. She shares projects, tutorials, and transformative personal stories, all aimed at inspiring readers to make knotting—and creativity in general—part of a meditative daily practice. The knots in this book are gorgeously documented step-by-step. Knotted projects abound—from wall hangings to a necklace, a dog leash, a hanging light, and more. At the heart of the story is the simple, empowering idea that a single year is all the time you need to make a life-changing creative leap.
Download or read book Creation written by Adam Rutherford and published by Penguin. This book was released on 2014-05-27 with total page 291 pages. Available in PDF, EPUB and Kindle. Book excerpt: Today’s scientists are radically exceeding the boundaries of evolution and engineering entirely novel creatures. Cutting edge “synthetic biology” may lead to solutions to some of the world’s most pressing crises and pave the way for inventions once relegated to science fiction. Meanwhile, these advances are shedding new light on the biggest mystery of all—how did life begin? As we come closer and closer to understanding the ancient root that connects all living things, Adam Rutherford shows how we may finally be able to achieve the creation of new life where none existed before.
Download or read book Reinventing Darwin written by Niles Eldredge and published by John Wiley & Sons. This book was released on 1995-04-17 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: An insider's provocative account of one of the most contentious debates in science today When Niles Eldredge and Stephen Jay Gould, two of the world's leading evolutionary theorists, proposed a bold new theory of evolution—the theory of "punctuated equilibria"—they stood the standard interpretation of Darwin on its head. They also ignited a furious debate about the true nature of evolution. On the one side are the geneticists. They contend that evolution proceeds slowly but surely, driven by competition among organisms to transmit their genes from generation to generation. On the other are the paleontologists, like Eldredge and Gould, who show in the fossil record that in fact evolution proceeds only sporadically. Long periods of no change—equilibria—are "punctuated" by episodes of rapid evolutionary activity. According to the paleontologists, this pattern shows that evolution is driven far more by environmental forces than by genetic competition. How can the prevailing views on evolution be so different? In Reinventing Darwin, Niles Eldredge offers a spirited account of the dispute and an impressive case for the paleontologists' side of the story. With the mastery that only a leading contributor to the debate can provide, he charts the course of theory from Darwin's day to the present and explores the fundamental mysteries and crucial questions that underlie the current quarrels. Is evolution fired by a gentle and persistent motor and fueled by the survival instincts of "selfish genes"? Or does it proceed in fits and starts, as the fossil record seems to show? What is the role of environmental changes such as habitat destruction and of cataclysmic events like meteor impacts? Are most species inherently stable, changing only very little until they succumb to extinction? Or are species highly adaptable, changing all the time? Eldredge sorts through the major findings and interpretations and presents a lively introduction to the leading edge of evolutionary theory today. Reinventing Darwin offers a rare insider's view of the sometimes contentious, but always stimulating work of scientific inquiry. PRAISE FOR NILES ELDREDGE'S PREVIOUS BOOKS The Miner's Canary: Unraveling the Mysteries of Extinction "The Miner's Canary rings with integrity. The author takes care to present opposing views. Some readers, indeed, might view Mr. Eldredge as a little too self-effacing; he is, after all, one of the world's leading experts in his field."—The New York Times Book Review Fossils: The Evolution and Extinction of Species ". . . an important and informative book. It is also delightfully idiosyncratic. This is no scholarly treatise defending academic argument. It is an essay for everyone interested in the story of earthly life."—The Christian Science Monitor Life Pulse: Episodes from the Story of the Fossil Record "This is Earth history on a grand scale; those who enjoy the works of Stephen Jay Gould will appreciate Life Pulse."—Publishers Weekly
Download or read book Reinventing Discovery written by Michael Nielsen and published by Princeton University Press. This book was released on 2020-04-07 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: How the internet and powerful online tools are democratizing and accelerating scientific discovery Reinventing Discovery argues that we are living at the dawn of the most dramatic change in science in more than three hundred years. This change is being driven by powerful cognitive tools, enabled by the internet, which are greatly accelerating scientific discovery. There are many books about how the internet is changing business, the workplace, or government. But this is the first book about something much more fundamental: how the internet is transforming our collective intelligence and our understanding of the world. From the collaborative mathematicians of the Polymath Project to the amateur astronomers of Galaxy Zoo, Reinventing Discovery tells the exciting story of the unprecedented new era in networked science. It will interest anyone who wants to learn about how the online world is revolutionizing scientific discovery—and why the revolution is just beginning.
