Download or read book Regulation of Macromolecular Synthesis By Low Molecular Weight Mediators written by Gebhard Koch and published by Elsevier. This book was released on 2012-12-02 with total page 401 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regulation of Macromolecular Synthesis by Low Molecular Weight Mediators contains the proceedings of the Workshop on Regulation of Macromolecular Synthesis by Low Molecular Weight Mediators held at Hamburg on May 29-31, 1979. The book discusses the functions and metabolism of guanosine 3',5'-bis(diphosphate); the purine nucleotides and sporulation; and the highly phosphorylated nucleotide in eukaryotes. The text also describes the alteration of translational mechanisms, as well as 2,5-oligoadenylic acid and interferon.
Download or read book Regulation of Macromolecular Synthesis by Low Molecular Weight Mediators written by Gebhard Koch and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Regulation of Macromolecular Synthesis by Low Weight Mediators written by Gebhard Koch and published by . This book was released on 1979 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Regulation of Macromolecular Synthesis by Low Weight Mediators written by Gebhard Koch and published by . This book was released on 1979 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Molecular Biology of Poliovirus written by F. Koch and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 603 pages. Available in PDF, EPUB and Kindle. Book excerpt: Years ago when we were asked to write a book on the present-day knowledge of the molecular biology of poliovirus, we did not expect that such an apparently simple task could involve so much time and effort. Our writing was hampered by the fact that both of us are full time "workers", so that this monograph is mainly a spare time expedience. The main attention of this book focuses on a detailed review of the molecular biology of poliovirus and especially on the advances of the last decade; medical and environmental aspects are only briefly mentioned. Observations from older studies are considered in view of more recent information. Some of the older ob servations provided fundamental insights and paved the way for present day research; too often such data has been neglected or independently rediscovered. Today, poliovirus research has again attracted considerable interest. High points gained within the last few years were the elucidation of the complete nucleotide sequences of the RNAs of the three poliovinls serotypes and the corresponding vaccine strains, the demonstration of genome evolution during transmission of poliovirus in an epidemic, further characterization of the antigenic sites on the virus particle and of the antigenic drift, characterization of alternate conforma tional states of the virion capsid, the development of monoclonal antibodies against some of the virus proteins, observations on the role of the plasma membrane, cytoskeleton, and cytoplasmic membranes as mediators in the virus induced redirection of the synthetic machinery of the host cell, and characteriza
Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1980 with total page 1340 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.
Download or read book Accuracy in Molecular Processes written by B. Kirkwood and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular biology proceeds at unremitting pace to unfold new secrets of the living world. Biology, long regarded as an inexact companion to physics and chemistry, has undergone transformation. Now, chemical and physical principles are tools in understanding highly complex biomolecular processes, whose origin lies in a history of chance, constraint and natural selection. The accuracy of these processes, often remarkably high, is crucial to their self perpetuation, both individually and collectively, as ingredients of the organism as a whole. In this book are presented thirteen chapters which deal with various facets of the accuracy problem. Subjects covered include: the specificity of enzymes; the fidelity of synthesis of proteins; the replication and repair of DNA: general schemes for the enhancement of biological accuracy; selection for an optimal balance between the costs and benefits of accuracy; and the possible relevance of molecular mistakes to the process of ageing. The viewpoints are distinct, yet complementary, and the book as a whole offers to researchers and students the first comprehensive account of this growing field.
Download or read book Ap4a and Other Dinucleoside Polyphosphates written by Alexander G. McLennan and published by CRC Press. This book was released on 2020-11-25 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ap4A and Other Dinucleoside Polyphosphates is the first compilation of contributions from major investigators involved in studying the chemistry and biology of dinucleoside polyphosphates. The book features reviews and original research (including unpublished and anecdotal material) covering the whole area of dinucleoside polyphosphate research from its inception to the present day. Ap4A and Other Dinucleoside Polyphosphates will be a useful reference for biological scientists studying nucleotide metabolism, cell signalling, DNA replication and repair, and cellular response to stress.
Download or read book Molecular Models of Photoresponsiveness written by G. Montagnoli and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Ribonucleases written by Giuseppe D'Alessio and published by Academic Press. This book was released on 1997-02-11 with total page 699 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pancreatic ribonuclease, the focus of highly productive scientific research for more than half a century and the only enzyme to be the basis of four Nobel prizes, has recently undergone a resurgence in popularity for the recognition of an extended ribonuclease superfamily with functions ranging from tumour growth and inhibition to self-recognition and neurotoxicity. This volume highlights the functional diversity of ribonucleases and reveals the emerging research opportunities provided by these enzymes. * Never before has discussion of the entire family of ribonucleases and related enzymes been covered in a single volume* Core chapters focus on the latest structures and functions of pancreatic-type ribonucleases* Structures and functions of intracellular ribonucleases and nondigestive members of the family are also covered* How ribonucleases continue to serve as excellent systems with which to uncover the secrets of protein chemistry is demonstrated
Download or read book Progress in Nucleic Acid Research and Molecular Biology written by and published by Academic Press. This book was released on 1989-09-21 with total page 343 pages. Available in PDF, EPUB and Kindle. Book excerpt: Progress in Nucleic Acid Research and Molecular Biology
Download or read book Cell and Molecular Biology of Artemia Development written by A. Warner and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The brine shrimp Artemia has become an important experimental system for studies of the developmental process. In recent years the shrimp has yielded considerable information on the pattern of development, bio chemistry, and gene structure and expression of crustaceans. This book is a compilation of research activity from twenty five of the most active re search laboratories working with brine shrimp in the above areas. It also represents the proceedings of a NATO Advanced Research Workshop held in Montreal, Canada, August 11-13, 1988. The book contains twenty nine full papers covering the major areas discussed at the workshop. In addition, one page abstracts representing seventeen poster presentations which were given at the workshop, and which were deemed to be most relevant to the theme of the book, are included. These are designated with an [al in the Table of Contents following the title of each paper. A considerable amount of discussion which took place during the workshop has not been included in the book because of space limitations. However, the editors will endeavour to make some of this in formation available at a later date through the Artemia Newsletter. In addition to the high percentage of invited speakers who attended and contributed to the workshop, the organizers would like to thank a number of participants who made valuable contributions to the major dis cussion sessions. These include: John Freeman, Michael Horst, Herman Slegers, Jack Vaughn, Frank Conte, Sandy McLennan, Clive Trotman and Patrick Sorgeloos.
Download or read book The Development Of Dictyostelium Discoideum written by William Loomis and published by Elsevier. This book was released on 2012-12-02 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Development of Dictyostelium discoideum consists of 11 chapters representing the 11 major aspects at which continuous progress are made in the study of Dictyostelium discoideum. This book begins with the discovery, classification, ecology, and development of Dictyostelium discoideum. It then outlines the advances in genetic manipulation and mutant isolation of the organism. Much of the advances in cell biology have been related to a better understanding of the composition and function of the cell membrane. Hence, analyses of Dictyostelium plasma membranes are collated. This reference material also describes the role of chemoattractants in organizing cell movements and the intracellular events triggered by occupancy of chemoreceptors. It also explains the understanding of the macromolecular components of the chemosensory system of Dictyostelium discoideum. It further discusses the cell motility, cell adhesion, morphogenetic signaling, cytodifferentiation, and gene expression in the species. Finally, the phenomenon of cell-type specification and regulation in this organism is addressed. This book will be valuable for those already familiar with the general outlines of Dictyostelium biology.
Download or read book Current Topics in Microbiology and Immunology written by M. Cooper and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Binding of various ligands (hormones, neurotransmitters, immunological stimuli) to membrane receptors induces the following changes: 1. Receptor redistribution (clustering, "capping") 2. Conformational changes that can be detected by fluorescent probes 3. Alteration in membrane fluidity (spin label and fluorescence polarization probes) 4. Changes in fluxes of ions and metabolites 5. Increased phospholipid turnover (especially of phosphatidyl inositol) 6. Activation of membrane-bound enzymes (adenyl cyclase, ATPase, transmethylases). Some of the early changes resulting from or associated with the binding (adsorption) of virions to the host cell membrane are of the same type. Adsorption of animal viruses to cells is the ftrst step in a chain of events resulting in the production of progeny virus on the one hand and in damage to cells and tissues on the other. In the classical studies of viral infection, cells are adsorbed with virus, usually for 60 min, and the changes induced by the virus in the host cell are recorded thereafter. In the past decade, more and more studies have been aimed at the events occurring in these ftrst 60 min of the so-called adsorption period. These studies deal with the nature of adsorption, e. g. , the ligand-receptor type of interaction between the virus and the cell membrane. Many receptors for viruses were identifted and so were the viral proteins which take part in adsorption.
Download or read book Biosynthesis Modification and Processing of Cellular and Viral Polyproteins written by Gebhard Koch and published by Elsevier. This book was released on 2012-12-02 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosynthesis, Modification, and Processing of Cellular and Viral Polyproteins presents the proceedings of the international conference held in Hamburg-Blankenese on May 27-31, 1980. The book discusses topics on polyproteins, polyfunctional proteins, precursor proteins, as well as the differences in synthesis and processing of ACTH/endorphin peptides in primary cultures of anterior and intermediate lobes of the pituitary. The text also presents evidence for a self-cleaving precursor of virus-coded protease, RNA-replicase, and VPg; and the role of Pr180gag-pol in the characterization and genetic analysis of retrovirus maturation.
Download or read book Protein Biosynthesis in Eukaryotes written by R. Perez-Bercoff and published by Springer Science & Business Media. This book was released on 2013-04-09 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bacillus Subtilis written by David Dubnau and published by Elsevier. This book was released on 2012-12-02 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Molecular Biology of the Bacilli, Volume I: Bacillus subtilis focuses on areas of research traditionally investigated in Bacillus subtilis, as well as topics in which outstanding progress has been made. It discusses the sporulation, defective bacteriophage, and transformation of Bacillus subtilis. Organized into 11 chapters, the book begins with the genetic map of Bacillus subtilis, followed by DNA replication and RNA polymerase of the said species. The book then describes the translational apparatus of Bacillus subtilis. It also explains the genetic transformation in Bacillus subtilis; the sporulation genes; the regulatory mechanisms in the development of lytic bacteriophages in this species; the temperate Bacillus subtilis phages; the specialized transduction in Bacillus subtilis; and molecular cloning in this organism. Lastly, the book considers the most economically important areas of the microbiological industry employing bacilli, including the production of enzymes, nucleosides, riboflavin, and preparations pathogenic to insects. This book will be useful to scientists who are concerned with the use of Bacillus subtilis as a tool for the study of molecular biology and to those who wish to increase the medical, veterinary, and industrial usefulness of this and related organisms.
