Download or read book Reconceiving the Gene written by Frederic Lawrence Holmes and published by Yale University Press. This book was released on 2008-10-01 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book relates how, between 1954 and 1961, the biologist Seymour Benzer mapped the fine structure of the rII region of the genome of the bacterial virus known as phage T4. Benzer’s accomplishments are widely recognized as a tipping point in mid-twentieth-century molecular biology when the nature of the gene was recast in molecular terms. More often than any other individual, he is considered to have led geneticists from the classical gene into the molecular age. Drawing on Benzer’s remarkably complete record of his experiments, his correspondence, and published sources, this book reconstructs how the former physicist initiated his work in phage biology and achieved his landmark investigation. The account of Benzer’s creativity as a researcher is a fascinating story that also reveals intriguing aspects common to the scientific enterprise.
Download or read book The Gene written by Hans-Jörg Rheinberger and published by University of Chicago Press. This book was released on 2018-01-26 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Few concepts played a more important role in twentieth-century life sciences than that of the gene. Yet at this moment, the field of genetics is undergoing radical conceptual transformation, and some scientists are questioning the very usefulness of the concept of the gene, arguing instead for more systemic perspectives. The time could not be better, therefore, for Hans-Jörg Rheinberger and Staffan Müller-Wille's magisterial history of the concept of the gene. Though the gene has long been the central organizing theme of biology, both conceptually and as an object of study, Rheinberger and Müller-Wille conclude that we have never even had a universally accepted, stable definition of it. Rather, the concept has been in continual flux—a state that, they contend, is typical of historically important and productive scientific concepts. It is that very openness to change and manipulation, the authors argue, that made it so useful: its very mutability enabled it to be useful while the technologies and approaches used to study and theorize about it changed dramatically.
Download or read book Reconceiving Schizophrenia written by Man Cheung Chung and published by Oxford University Press, USA. This book was released on 2007 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Schizophrenia has been investigated predominantly from psychological, psychiatric and neurobiological perspectives. This text examines it from a philosophical point of view.
Download or read book Babies by Design written by Ronald M. Green and published by Yale University Press. This book was released on 2007-01-01 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: Product Description: We stand on the brink of unprecedented growth in our ability to understand and change the human genome. New reproductive technologies now enable parents to select some genetic traits for their children, and soon it will be possible to begin to shape ourselves as a species. Despite the loud cries of alarm that such a prospect inspires, Ronald Green argues that we will, and we should, undertake the direction of our own evolution. A leader in the bioethics community, Green offers a scientifically and ethically informed view of human genetic self-modification and the possibilities it opens up for a better future. Fears of a terrible Brave New World or a new eugenics movement are overblown, he maintains, and in the more likely future, genetic modifications may improve parents' ability to enhance children's lives and may even promote social justice. The author outlines the new capabilities of genomic science, addresses urgent questions of safety that genetic interventions pose, and explores questions of parenting and justice. He also examines the religious implications of gene modification. Babies by design are assuredly in the future, Green concludes, and by making responsible choices as we enter that future, we can incorporate gene technology in a new age of human adventure.
Download or read book The Epistemology of Development Evolution and Genetics written by Richard Burian and published by Cambridge University Press. This book was released on 2005 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: These essays examine the developments in three fundamental biological disciplines--embryology, evolutionary biology, and genetics. These disciplines were in conflict for much of the 20th century and the essays in this collection examine key methodological problems within these disciplines and the difficulties faced in overcoming the conflicts between them. Burian skillfully weaves together historical appreciation of the settings within which scientists work, substantial knowledge of the biological problems at stake and the methodological and philosophical issues faced in integrating biological knowledge drawn from disparate sources.
Download or read book Conceiving Parenthood written by Amy Laura Hall and published by Wm. B. Eerdmans Publishing. This book was released on 2008 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The book is replete with photos and advertisements from popular magazines from the 1930s through the 1950s."--Jacket.
Download or read book Life s Blueprint written by Benny Shilo and published by Yale University Press. This book was released on 2014-10-28 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the span of just three decades, scientific understanding of the formation of embryos has undergone a major revolution. The implications of these new research findings have an immediate bearing on human health and future therapies, yet most nonscientists remain quite unaware of the exciting news. In this engaging book, a distinguished geneticist offers a clear, jargon-free overview of the field of developmental biology. Benny Shilo transforms complicated scientific paradigms into understandable ideas, employing an array of photographic images to demonstrate analogies between the cells of an embryo and human society. Shilo’s innovative approach highlights important concepts in a way that will be intuitive and resonant with readers’ own experiences. The author explains what is now known about the mechanisms of embryonic development and the commanding role of genes. For each paradigm under discussion, he provides both a scientific image and a photograph he has taken in the human world. These pairs of images imply powerful metaphors, such as the similarities between communication among cells and among human beings, or between rules embedded in the genome and laws that govern human society. The book concludes with a glimpse of promising future possibilities, including the generation of tissues and organs for use as “spare parts.”
Download or read book Making Kin Not Population written by Adele E. Clarke and published by . This book was released on 2018 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the planet's human numbers grow and environmental concerns proliferate, natural scientists, economists, and policy-makers are increasingly turning to new and old questions about families and kinship as matters of concern. From government programs designed to fight declining birth rates in Europe and East Asia, to controversial policies seeking to curb population growth in countries where birth rates remain high, to increasing income inequality transnationally, issues of reproduction introduce new and complicated moral and political quandaries. Making Kin Not Population ends the silence on these issues with essays from leading anti-racist, ecologically-concerned, feminist scholars. Though not always in accord, these contributors provide bold analyses of complex issues of intimacy and kinship, from reproductive justice to environmental justice, and from human and nonhuman genocides to new practices for making families and kin. This timely work offers vital proposals for forging innovative personal and public connections in the contemporary world.
Download or read book Reconceiving Reproductive Health Theological and Christian Ethical Reflections written by Manitza Kotzé and published by AOSIS. This book was released on 2019-12-12 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: While reproduction is fairly often touched upon in theological and Christian ethical discussions, reproductive health is not. However, reproductive health is a matter of theological and ethical concern. Discussion pertaining to reproductive health includes a number of debates about, for instance, abortion and the termination of pregnancy, reproductive loss, childlessness, infertility, stillbirth, miscarriage and adoption. Additionally, new reproductive possibilities made available by the development of reproductive technology have necessitated theological and ethical reflection on, for example, surrogacy, post-menopausal pregnancies, litter births, single mothers or fathers by choice, in vitro fertilisation and the so-called saviour siblings. These new developments compel us to reconceive our notions of what reproductive health is or should be. Many of these topics are receiving increasing attention in a variety of theological publications. The focus of this volume is unique, however, and to the best of our knowledge, this is the first volume dealing not only with reproductive issues, but also reflecting theologically and ethically on reproductive health. It makes a contribution by providing a variety of perspectives from different theological fields on this theme, and in many chapters, focussing especially on the South African context. These discussions are also part of urgent debates within churches, which require developing life-giving theological language and imaginative theological alternatives that may speak to experiences of matters relating to reproductive health. The popular books, TV series and films that touch upon these discussions including The Handmaids Tale and Mother! strengthen the perception that a more in-depth theological and ethical discussion on the theme may be necessary, particularly towards exploring stories and confessions from our faith tradition that may provide us with a timely opportunity to do the important work of theological reconceiving.
Download or read book Ribbon of Darkness written by Barbara Maria Stafford and published by University of Chicago Press. This book was released on 2019-06-18 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the course of her career, Barbara Stafford has established herself the preeminent scholar of the intersections of the arts and sciences, articulating new theories and methods for understanding the sublime, the mysterious, the inscrutable. Omnivorous in her research, she has published work that embraces neuroscience and philosophy, biology and culture, pinpointing connections among each discipline’s parallel concerns. Ribbon of Darkness is a monument to the scope of her work and the range of her intellect. At times associative, but always incisive, the essays in this new volume take on a distinctly contemporary purpose: to uncover the ethical force and moral aspects of overlapping scientific and creative inquiries. This shared territory, Stafford argues, offers important insights into—and clarifications of—current dilemmas about personhood, the supposedly menial nature of manual skill, the questionable borderlands of gene editing, the potentially refining value of dualism, and the limits of a materialist worldview. Stafford organizes these essays around three concepts that structure the book: inscrutability, ineffability, and intuitability. All three, she explains, allow us to examine how both the arts and the sciences imaginatively infer meaning from the “veiled behavior of matter,” bringing these historically divided subjects into a shared intellectual inquiry and imbuing them with an ethical urgency. A vanguard work at the intersection of the arts and sciences, this book will be sure to guide readers from either realm into unfamiliar yet undeniably fertile territory.
Download or read book Brenner s Encyclopedia of Genetics written by Stanley Maloy and published by Academic Press. This book was released on 2013-03-03 with total page 4360 pages. Available in PDF, EPUB and Kindle. Book excerpt: The explosion of the field of genetics over the last decade, with the new technologies that have stimulated research, suggests that a new sort of reference work is needed to keep pace with such a fast-moving and interdisciplinary field. Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set, builds on the foundation of the first edition by addressing many of the key subfields of genetics that were just in their infancy when the first edition was published. The currency and accessibility of this foundational content will be unrivalled, making this work useful for scientists and non-scientists alike. Featuring relatively short entries on genetics topics written by experts in that topic, Brenner's Encyclopedia of Genetics, Second Edition, Seven Volume Set provides an effective way to quickly learn about any aspect of genetics, from Abortive Transduction to Zygotes. Adding to its utility, the work provides short entries that briefly define key terms, and a guide to additional reading and relevant websites for further study. Many of the entries include figures to explain difficult concepts. Key terms in related areas such as biochemistry, cell, and molecular biology are also included, and there are entries that describe historical figures in genetics, providing insights into their careers and discoveries. This 7-volume set represents a 25% expansion from the first edition, with over 1600 articles encompassing this burgeoning field Thoroughly up-to-date, with many new topics and subfields covered that were in their infancy or not inexistence at the time of the first edition. Timely coverage of emergent areas such as epigenetics, personalized genomic medicine, pharmacogenetics, and genetic enhancement technologies Interdisciplinary and global in its outlook, as befits the field of genetics Brief articles, written by experts in the field, which not only discuss, define, and explain key elements of the field, but also provide definition of key terms, suggestions for further reading, and biographical sketches of the key people in the history of genetics
Download or read book The Black Box of Biology written by Michel Morange and published by Harvard University Press. This book was released on 2020-06-09 with total page 529 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this masterful account, a historian of science surveys the molecular biology revolution, its origin and continuing impact. Since the 1930s, a molecular vision has been transforming biology. Michel Morange provides an incisive and overarching history of this transformation, from the early attempts to explain organisms by the structure of their chemical components, to the birth and consolidation of genetics, to the latest technologies and discoveries enabled by the new science of life. Morange revisits A History of Molecular Biology and offers new insights from the past twenty years into his analysis. The Black Box of Biology shows that what led to the incredible transformation of biology was not a simple accumulation of new results, but the molecularization of a large part of biology. In fact, Morange argues, the greatest biological achievements of the past few decades should still be understood within the molecular paradigm. What has happened is not the displacement of molecular biology by other techniques and avenues of research, but rather the fusion of molecular principles and concepts with those of other disciplines, including genetics, physics, structural chemistry, and computational biology. This has produced decisive changes, including the discoveries of regulatory RNAs, the development of massive scientific programs such as human genome sequencing, and the emergence of synthetic biology, systems biology, and epigenetics. Original, persuasive, and breathtaking in its scope, The Black Box of Biology sets a new standard for the history of the ongoing molecular revolution.
Download or read book Philosophy of Behavioral Biology written by Kathryn S. Plaisance and published by Springer Science & Business Media. This book was released on 2011-10-05 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a broad overview of issues in the philosophy of behavioral biology, covering four main themes: genetic, developmental, evolutionary, and neurobiological explanations of behavior. It is both interdisciplinary and empirically informed in its approach, addressing philosophical issues that arise from recent scientific findings in biological research on human and non-human animal behavior. Accordingly, it includes papers by professional philosophers and philosophers of science, as well as practicing scientists. Much of the work in this volume builds on presentations given at the international conference, “Biological Explanations of Behavior: Philosophical Perspectives”, held in 2008 at the Leibniz Universität Hannover in Germany. The volume is intended to be of interest to a broad range of audiences, which includes philosophers (e.g., philosophers of mind, philosophers of biology, and metaethicists), as well as practicing scientists, such as biologists or psychologists whose interests relate to biological explanations of behavior.
Download or read book The Genetic Lottery written by Kathryn Paige Harden and published by Princeton University Press. This book was released on 2021-09-21 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: A provocative and timely case for how the science of genetics can help create a more just and equal society In recent years, scientists like Kathryn Paige Harden have shown that DNA makes us different, in our personalities and in our health—and in ways that matter for educational and economic success in our current society. In The Genetic Lottery, Harden introduces readers to the latest genetic science, dismantling dangerous ideas about racial superiority and challenging us to grapple with what equality really means in a world where people are born different. Weaving together personal stories with scientific evidence, Harden shows why our refusal to recognize the power of DNA perpetuates the myth of meritocracy, and argues that we must acknowledge the role of genetic luck if we are ever to create a fair society. Reclaiming genetic science from the legacy of eugenics, this groundbreaking book offers a bold new vision of society where everyone thrives, regardless of how one fares in the genetic lottery.
Download or read book Collecting Experiments written by Bruno J. Strasser and published by University of Chicago Press. This book was released on 2019-06-04 with total page 421 pages. Available in PDF, EPUB and Kindle. Book excerpt: Databases have revolutionized nearly every aspect of our lives. Information of all sorts is being collected on a massive scale, from Google to Facebook and well beyond. But as the amount of information in databases explodes, we are forced to reassess our ideas about what knowledge is, how it is produced, to whom it belongs, and who can be credited for producing it. Every scientist working today draws on databases to produce scientific knowledge. Databases have become more common than microscopes, voltmeters, and test tubes, and the increasing amount of data has led to major changes in research practices and profound reflections on the proper professional roles of data producers, collectors, curators, and analysts. Collecting Experiments traces the development and use of data collections, especially in the experimental life sciences, from the early twentieth century to the present. It shows that the current revolution is best understood as the coming together of two older ways of knowing—collecting and experimenting, the museum and the laboratory. Ultimately, Bruno J. Strasser argues that by serving as knowledge repositories, as well as indispensable tools for producing new knowledge, these databases function as digital museums for the twenty-first century.
Download or read book A Cultural History of Heredity written by Staffan Müller-Wille and published by University of Chicago Press. This book was released on 2012-06-22 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Thought-provoking…any scientist interested in genetics will find this an enlightening look at the history of this field.”—Quarterly Review of Biology It was only around 1800 that heredity began to enter debates among physicians, breeders, and naturalists. Soon thereafter, it evolved into one of the most fundamental concepts of biology. Here, Staffan Muller-Wille and Hans-Jorg Rheinberger offer a succinct cultural history of the scientific concept of heredity. They outline the dramatic changes the idea has undergone since the early modern period and describe the political and technological developments that brought about these changes. They begin with an account of premodern theories of generation, showing that these were concerned with the procreation of individuals rather than with hereditary transmission, and reveal that when hereditarian thinking first emerged, it did so in a variety of cultural domains, such as politics and law, medicine, natural history, breeding, and anthropology. The authors then track theories of heredity from the late nineteenth century—when leading biologists considered it in light of growing societal concerns with race and eugenics—through the rise of classical and molecular genetics in the twentieth century, to today, as researchers apply sophisticated information technologies to understand heredity. What we come to see from this exquisite history is why it took such a long time for heredity to become a prominent concept in the life sciences, and why it gained such overwhelming importance in those sciences and the broader culture over the last two centuries.
Download or read book Gene Drives at Tipping Points written by Arnim von Gleich and published by Springer Nature. This book was released on 2020-01-01 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book reports on a pilot project aiming at collecting information on the socio-ecological risks that could arise in the event of an uncontrolled spread of genetically engineered organisms into the environment. The researchers will, for instance, be taking a closer look at genetically engineered oilseed rape, genetically engineered olive flies as well as plants and animals with so-called gene drives. The book mainly adresses researchers.
