Download or read book Recent Progress in Molecular Biology and Immunology Provides New Aspects for the Pathophysiology of Cutaneous T cell Lymphomas written by Reinhard Dummer and published by . This book was released on 1994 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book T Cell and NK Cell Lymphomas written by Christiane Querfeld and published by Springer. This book was released on 2018-12-30 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, a group of internationally distinguished lymphoma experts provide a comprehensive review of the most important advances in the biology, diagnosis, and therapy of T cell and NK cell malignancies. In particular, it demonstrates in detail how advances in our understanding of the tumor microenvironment and molecular biology have helped to elucidate the pathogenesis of these lymphomas, improve diagnostic and prognostic accuracy, and develop novel therapies that promise improved patient outcomes. Individual chapters are devoted to particular tumor types and subtypes, and all aspects of transplantation for patients with T cell and NK cell lymphomas are discussed. As such, the book offers a valuable resource for hematologists, oncologists, hematopathologists, and all those seeking an up-to-date overview of how new, targeted therapies are delivering better disease control and improved quality of life.
Download or read book T Cell Lymphomas written by Francine Foss and published by Springer Science & Business Media. This book was released on 2012-11-06 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mature T and NK cell lymphomas are rare, comprising approximately 10% of all malignant lymphomas. The incidence of T-cell lymphoma is variable around the world, with a higher incidence compared to B-cell lymphomas in the Asian basin. While the overall incidence of B-cell lymphomas has begun to decline in the United States, the incidence of T-cell lymphomas continues to rise. Over the last decade, a number of novel agents have been developed which target T-cell lymphomas and studies have identified novel genes and pathways associated with lymphomagenesis in T-cells. This comprehensive volume examines the clinical and biological aspects of the T-cell lymphoproliferative disorders in adults and children. The book includes an overview of both the cutaneous and the systemic T-cell malignancies and addresses the classification of T-cell lymphomas, the clinical features of each subtype, and the relevant molecular and genetic studies. Clinical outcomes and treatment strategies are discussed with an emphasis on the development of novel biological and targeted therapies. An outstanding resource for hematologists and oncologists, this book gathers insights from experts in the field and provides the most up-to-date information on all of the T-cell lymphoma subgroups and current and emerging therapies.
Download or read book Cutaneous T Cell Lymphoma written by Herschel S. Zackheim and published by CRC Press. This book was released on 2004-10-28 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cutaneous T-cell lymphoma (CTCL) is a general term for many lymphomas of the skin including mycosis Fungoides and Sezary syndrome. This book presents the state of the art in CTCL epidemiology, clinical features, pathology, immunochemistry, diagnostic molecular techniques, staging and prognosis, and treatment. Edited by one of the leading experts in
Download or read book Cutaneous Lymphomas An Issue of Surgical Pathology Clinics written by Antonio Subtil and published by Elsevier Health Sciences. This book was released on 2014-06-28 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knowledge of cutaneous lymphomas has been growing significantly as a result of important discoveries in immunology, molecular biology, and immunohistochemistry. Improved clinical pathologic correlation and follow-up data, as well as the synergistic collaboration among different lymphoma registries and specialists from several academic medical centers have greatly contributed to the understanding of the difficult field of cutaneous lymphoproliferative disorders. While these advances have increased understanding of skin lymphomas, they have also produced an extensive and sometimes confusing litany of articles, studies, and classification schemes. This issue on Cutaneous Lymphomas in Surgical Pathology Clinics provides an organized and updated review of this challenging topic by leading experts. It bridges critical knowledge gaps in the diagnosis of cutaneous lymphomas. Sezary Syndrome, Mycosis Fungoides and variants are presented along with B-cell, CD30, lymphoproliferative disorders among others. In addition to multiple clinical and microscopic images, tables and algorithms are presented to aid in diagnosis and staging. Beyond its usefulness to general pathologists, dermatopathologists, and hematopathologists, this information is intended to be helpful for dermatologists, hematologists/oncologists, fellows, and residents.
Download or read book New Research on Cutaneous Lymphomas written by Angel Fernandez-Flores and published by Nova Publishers. This book was released on 2006-09 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cutaneous lymphoid infiltrates which are suspicious for lymphoma, are always important challenges for the general pathologist who faces them occasionally. Many times they are also difficult even for the dermatopathologist, and the most modern diagnostic weapons sometimes play a crucial role in the differential diagnosis with other non-malignant entities, as well as between the different types of lymphomas. Clinically, they sometimes simulate many other conditions, and are not always easy to be recognise by the dermatologist. In 2005, a new classification of cutaneous lymphomas was published, in an attempt to achieve a better comprehension of the nature and behaviour of these tumours. Nevertheless, many new aspects of pathogenesis, diagnosis and differential diagnosis, are constantly appearing in medical literature. This current book is an attempt to present to the reader, the field of cutaneous lymphomas in a way that can be useful in daily practice, either as a general surgical pathologist, a dermatologist, or a dermatopathologist. At the same time, the reader will find updated information which will probably be very helpful in order to face confidently most of the difficult clinical and histopathologic cases. The book goes through most of the cutaneous lymphomas in systematic order, either B-cell, T-cell, or Hodgkin type, presenting the clinical, and morphological aspects, which include many of the most recent molecular contributions. Many of the chapters also provide a therapeutic approach.
Download or read book The Peripheral T Cell Lymphomas written by Owen A. O'Connor and published by John Wiley & Sons. This book was released on 2021-02-19 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: THE PERIPHERAL T-CELL LYMPHOMAS Provides a comprehensive look at Peripheral T-Cell lymphomas, including the group’s unique geographic distribution, underlying genetics, and novel treatments Peripheral T-Cell lymphomas (PTCL) are a diverse group of lymphoid malignancies that develop from mature T cells and natural killer (NK) cells. PTCL represent 10-15% of all cases of non-Hodgkin lymphoma in the US, and up to 20-25% of cases in South America, Asia, and other regions around the world. The role of different etiologic factors and the variation of geographic distribution makes PTCL one of the most difficult types of cancer to understand and treat. For the first time in a single volume, The Peripheral T-Cell Lymphomas presents a comprehensive survey of this complex and rare group of blood cancers. Featuring contributions from an international team of leading authorities in the various aspects of PTCL, this authoritative text covers biology, epidemiology, classification, approved and emerging drugs, molecular genetics, and more. Detailed clinical chapters address diagnosis, prognosis, and treatment of each of the major PTCL subtypes identified in the 2018 WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues. This much-needed resource: Covers the biological basis, epidemiology, classification, and treatment of PTCL Discusses the future of the field, including global collaboration efforts and novel approaches to PCTL Explores the role of biologics in PTCL and autologous and allogeneic stem-cell transplantation Offers new insights on molecular pathogenesis, innovative therapeutics, and novel drug combinations Features contributions from the Chairs The T-Cell Lymphoma Forum: the world’s largest meeting focused on PTCL Reflecting the unique epidemiology and genetic diversity of the PTCL, The Peripheral T-Cell Lymphomas is an indispensable source of data, insight, and references for the medical community, particularly oncologists and hematologists in both training and practice.
Download or read book T Cell Lymphomas written by Francine Foss and published by Humana Press. This book was released on 2016-08-23 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mature T and NK cell lymphomas are rare, comprising approximately 10% of all malignant lymphomas. The incidence of T-cell lymphoma is variable around the world, with a higher incidence compared to B-cell lymphomas in the Asian basin. While the overall incidence of B-cell lymphomas has begun to decline in the United States, the incidence of T-cell lymphomas continues to rise. Over the last decade, a number of novel agents have been developed which target T-cell lymphomas and studies have identified novel genes and pathways associated with lymphomagenesis in T-cells. This comprehensive volume examines the clinical and biological aspects of the T-cell lymphoproliferative disorders in adults and children. The book includes an overview of both the cutaneous and the systemic T-cell malignancies and addresses the classification of T-cell lymphomas, the clinical features of each subtype, and the relevant molecular and genetic studies. Clinical outcomes and treatment strategies are discussed with an emphasis on the development of novel biological and targeted therapies. An outstanding resource for hematologists and oncologists, this book gathers insights from experts in the field and provides the most up-to-date information on all of the T-cell lymphoma subgroups and current and emerging therapies.
Download or read book Fast Facts Cutaneous T cell Lymphoma written by Paul L Haun and published by Karger Medical and Scientific Publishers. This book was released on 2019-04-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cutaneous T-cell lymphoma (CTCL) has been described as a 'great mimicker'. The correct diagnosis hinges on effective collaboration between clinicians and pathologists to correlate pathological and clinical findings. The patient's history, lesion description and diagnostic work-up will help the pathologist interpret the histopathology, whilst the clinician’s diagnosis is aided by a clear understanding the terminology used in the pathology report. The treatment of early and advanced mycosis fungoides and its variants is potentially lifelong, with patients typically cycling among treatments, interspersed with periods of expectant therapy providing palliation and symptomatic relief. Effective management requires knowledge of the wide range of options, how they are used, and their side-effect profile, in order to tailor treatment to the individual patient.
Download or read book Peripheral T cell Lymphomas written by Pier Paolo Piccaluga and published by BoD – Books on Demand. This book was released on 2019-08-07 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book the reader will find a collection of chapters written by different research teams describing different aspects of peripheral T-cell lymphoma pathobiology, classification, and treatment. This work is mainly addressed to researchers already working in this area, but it is also accessible to anyone with a scientific background who desires to have an updated overview of the recent progress in this domain. It will also be valuable to scientists and physicians who have become newly involved in this field. Each chapter is self-contained and can be read independently of the others. This book intends to provide highlights of the current research as well as the current gold standards for diagnosis and treatment of these diseases, showing the recent advances in the personalized approach to T-cell derived lymphomas.
Download or read book Chronic Leukemias and Lymphomas written by Gary J. Schiller and published by Springer Science & Business Media. This book was released on 2002-10-16 with total page 325 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Chronic Leukemias and Lymphomas: Clinical Management, a panel of recognized experts in hematological oncology describe the unique biological features of indolent hematologic neoplasms, providing powerful insight into their clinical manifestation, highlighting potential targets for novel therapies, and distinguishing these disorders from aggressive lymphoma and Hodgkin's disease. In their integrated surveys of these chronic myeloproliferative and lymphoproliferative disorders, the authors emphasize such unique entities as prolymphocytic leukemias and cutaneous lymphomas. Special emphasis is given to the mechanisms of disease progression with authoritative insights into the promising new era of antineoplastic pharmacology.
Download or read book The Cutaneous Lymphoid Proliferations written by Cynthia M. Magro and published by John Wiley & Sons. This book was released on 2016-02-23 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: A masterful and thorough revision of the only single-source, authoritative reference on cutaneous lymphoproliferative disease. Classic reference for unsurpassed coverage of lymphocytic infiltrates of the human skin Covers a broad spectrum of topics ranging from the role of the immune system in the pathogenesis of cutaneous lymphocytic infiltrates to one describing the immunohistochemica nd molecular aspects of lymphoid neoplasia. Each chapter contains an extensive array of ‘clinical vignettes’ clearly showing the application of principles and treatment techniques discussed in the chapter Presents a succinct and logical approach to the diagnosis of most cutaneous lymphocytic infiltrates and discusses the interplay between the immune system in the propagation of lymphocytic infiltrates focusing on the role of iatrogenic and endogenous immune dysregulation. The molecular and cytogenetic basis of lymphoid neoplasia is considered in great detail. Contains hundreds of full-color, high-quality clinical and histologic photographs, with over 200 new images in the new edition
Download or read book Fast Facts Diagnosing Cutaneous T Cell Lymphoma written by Paul L. Haun and published by Karger Medical and Scientific Publishers. This book was released on 2016-08-18 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cutaneous T-cell lymphoma (CTCL) is one of the 'great mimickers'. To be certain of the diagnosis, there must be clear correlation between the pathological and clinical findings, making collaboration between clinicians and pathologists essential. Knowing the patient's history, lesion description and diagnostic work-up will help the pathologist make a more informed decision with respect to the histopathology under the microscope. Likewise, understanding the terminology used in the pathology report will improve the clarity of the clinician’s diagnosis. 'Fast Facts: Diagnosing Cutaneous T-Cell Lymphoma' is designed to help primary care providers, dermatologists and pathologists speak the same language. With over 100 superb clinical and pathological images, this concise, practical handbook will ensure clear communication with respect to the clinical presentation, histopathology and immunophenotyping of: • early and advanced mycosis fungoides and its variants • Sézary syndrome • other non-mycosis fungoides CTCLs. It is therefore essential reading for all pathologists, non-specialist clinicians and dermatology trainees.
Download or read book Hodgkin s and Non Hodgkin s Lymphoma written by John P. Leonard and published by Springer Science & Business Media. This book was released on 2008-03-05 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years a dramatic increase in knowledge of the biology of the lymphomas has been accompanied by the emergence of new treatments offering improvements in efficacy and reduction in toxicity. In this volume an internationally recognized group of experts review relevant aspects of the biology, diagnosis and management, with particular emphasis on the emerging data available for this disease.
Download or read book Cutaneous T Cell Lymphoma CTCL written by Haipeng Shao and published by . This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cutaneous T-cell lymphomas (CTCLs) are a heterogeneous group of Non-Hodgkin lymphomas with a variety of clinical presentation and outcomes. The diagnosis and treatment of CTCLs have evolved significantly with advances in our understanding of their pathogenesis and biological behaviors through immunophenotypic, molecular, and cytogenetic analysis and clinical correlation. The diagnosis and classification of CTCLs depend on integration of clinical presentation, histology, immunophenotype, molecular and/or cytogenetic findings. Accurate diagnosis and staging are essential for proper treatment and prognosis of the patients. The book Cutaneous T-Cell Lymphoma (CTCL): Clinical Features, Diagnosis and Treatment Options aims to provide the most up-to-date knowledge of the diagnosis, prognosis and treatment strategies of CTCL. Each chapter focuses on a different aspect of CTCL: clinical presentation, pathology, therapeutic options, role of radiation therapy, and in-depth discussion of the specific subtypes of CTCL classified under the most recent World Health Organization (WHO) classification of lymphoid neoplasms. The authors are practicing physicians in major medical centers and university hospitals, and are familiar with the challenges of diagnosing and treating patients with CTCL. The book is written for the practicing physicians and provides practical information and advice for their daily practice. Residents, fellows and other trainees will also find the contents of this book useful for their education and board preparation. The authors hope that the material covered in this book will serve as a foundation for the readers to keep up with future developments in the field.
Download or read book Adult T cell Leukemia Lymphoma written by Toshiki Watanabe and published by Springer. This book was released on 2018-07-25 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides essential information on the epidemiology, molecular and genetic features, anti-CCR4 antibody therapy and a nationwide study of transplantation on human T-leukemia virus type-I (HTLV-1) and adult T-cell leukemia/lymphoma (ATL). This rare but important disease has restricted endemic areas and distinct clinical features such as a high frequency of hypercalcemia, strong predisposition to infection and poor response to chemotherapy, aspects which set ATL apart from other types of non-Hodgkin lymphoma. Given the small number of patients, enrollment in clinical trials has not been feasible, and establishing treatment standard has been difficult but new evidence, such as results of nationwide studies on transplantation, have shown new insights and potential treatments. Based on recent evidence, the book presents new treatment methods for ATL and infection prevention of HTLV-1, enabling clinicians, researchers and post-docs specializing in hematology and virology to gain a valuable overview of the disease.
Download or read book Cutaneous T cell Lymphoma written by Richard L. Edelson and published by . This book was released on 1980 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt:
