Download or read book Recent Advances in Steroid Hormone Action written by V. K. Moudgil and published by Walter de Gruyter GmbH & Co KG. This book was released on 2019-07-22 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: No detailed description available for "Recent Advances in Steroid Hormone Action".
Download or read book Molecular Mechanism of Steroid Hormone Action written by Virinder K. Moudgil and published by De Gruyter. This book was released on 1985 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Steroid Receptors in Health and Disease written by Virinder Moudgil and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last two decades, progress in steroid hormone research has resulted in the development of new approaches to contraception as well as diagnosis and treatment of endocrine disorders and cancers. Although significant advances have been made in the purification, characterization, immunochemistry and molecular biology of steroid receptors, the precise molecular mechanism of steroid hormone action has remained obscure. This book captures the detailed presentations made at the first conference on Steroid Receptors in Health and Disease held at Meadow Brook Hall, Oakland University in the fall of 1987. The purpose of this international con ference was to facilitate scientific exchange toward a better understand ing of the mode of action of steroid hormones. The scientific sessions consisted of poster presentations and state-of-the-art lectures, the latter of which make up this volume. The first chapter is meant to provide the reader with a more general background of the topics covered in the book, as well as to discuss certain theme-related issues that are either not yet well-established or accepted or are in the stage of infancy. It is hoped that this volume will serve as a useful treatise for students and investigators interested in basic and clinical aspects of biological regulation by steroid hormones. A task of this magnitude could not have been undertaken without the encouragement, advice and continued generous assistance of the members of the scientific committee. I am gratefully indebted to Drs.
Download or read book Recent Advances in Steroid Biochemistry written by J. R. Pasqualini and published by Elsevier. This book was released on 2014-05-18 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent Advances in Steroid Biochemistry contains the proceedings of the Second International Symposium of the Journal of Steroid Biochemistry. Separating 38 papers as chapters, this book discusses the partial purification of steroid-receptor complexes; enzymatic techniques in steroid assay; mass fragmentography of steroid hormones; biological consequences of 18-hydroxylation; and steroidogenesis in adrenal cells. This text also explores the regulation of steroidogenesis in testis; androgen binding proteins in different testis compartments; nuclear acceptor sites for glucocorticoid receptors; estrogen receptors in the pancreas; and molecular mechanisms of steroid hormone action.
Download or read book Neuroplasticity Development and Steroid Hormone Action written by Robert J. Handa and published by CRC Press. This book was released on 2001-07-30 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: A compilation of cutting-edge research, Neuroplasticity, Development, and Steroid Hormone Action explores the effects of steroid hormones on brain development, function, and aging. The experimental approaches used by the authors ranges from molecular to behavioral and endocrine to neurobiological. It contains scientific photographs, line drawings, tables, color illustrations, and graphs, this interesting and timely text covers the neuroplastic effects of steroid hormones throughout the lifetime of various animal models, such as bees, fish, lizards, turtles, birds, mice, rats, and primates.
Download or read book Steroid and Sterol Hormone Action written by Thomas C. Spelsberg and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to focus attention on recent developments in steroid and sterol hormone action. Many authors have generously contributed to the book. As a result, there is a great diversity of opinion! A majority of the chapters deal with steroid or sterol hormone receptors. This is not meant to imply that receptor-mediated mechanisms are the sole or even the most important mechanisms by which steroid hormones act in the cell. There is wealth of evidence showing that other, non-receptor events, are important also. Steroid hormone recep tor research and the study of nuclear events mediated by steroids are presently the most intensely studied aspects of sterol hormone action and our selection of topics reflects this trend. We have also included chapters on vitamin 0 sterols and thyroid hormone in the book, as there is pood evidence that these hormones act in a manner similar to other classical steroids. 1 IMMUNOCHARACTERIZATION OF THE NUCLEAR ACCEPTOR SITES FOR THE AVIAN OVIDUCT PROGESTERONE RECEPTOR A. GOLDBERGER, M. HORTON, T. C. SPELSBERG Department of Biochemistry and Molecular Biology, Mayo Clinic and Mayo Graduate School of Medicine, Rochester, MN 55905 INTRODUCTION It is well known that steroid hormones, certain vitamins and sterols, enter target cells and bind to specific protein receptors in the cyto plasm or nucleus (1-4). This binding is saturable, high affinity, and steroid specific.
Download or read book Steroid Hormone Receptors Basic and Clinical Aspects written by V. K. Moudgil and published by Springer Science & Business Media. This book was released on 2013-03-13 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past few years have witnessed the emergence of steroid hormones as the wonder molecules which generate as much discussion in the scientific literature as they do in a typical living room. This transition has been a result of the tremendous public and scientific interest in the normal functioning of the hor mones as well their suggested involvement in several clinical conditions. In the recent past, notable scientific and technological advances have been made in the areas of contraception and regulation of fertility. Steroid receptors are the indis pensable mediators of hormonal responses and are complex protein molecules which appear to exist in association with other, yet undefined, proteins and/or factors. Receptors for vitamin D, retinoic acid and the thyroid hormones share structural similarities with steroid receptors, and the roster of this superfamily is still expanding. While our knowledge of the diversity and magnitude of steroid effects has advanced, the precise mode of steroid hormone action has alluded investigators. This volume brings together an international team of prominent investigators who discuss their most recent work on the basic and clinical aspects of steroid/nuclear receptors. The contributions represent updated versions of the invited presentations made at The Second Meadow Brook Conference on Steroid Receptors in Health and Disease. I am grateful to my colleagues on the Scientific Committee: Etienne Baulieu, Jack Gorski, Benita Katzenellenbogen, David Toft and James WittJiff, who provided the vision and guidance in formulating an out standing program.
Download or read book Development of Responsiveness to Steroid Hormones written by Alvin M. Kaye and published by Elsevier. This book was released on 2013-10-22 with total page 497 pages. Available in PDF, EPUB and Kindle. Book excerpt: Development of Responsiveness to Steroid Hormones is a collection of papers presented at the Bat-Sheva Seminar of the same name which was held in Rehovot, Israel, on October 18-26, 1978 and sponsored by the Bat-Sheva de Rothschild Foundation for the Advancement of Science in Israel in cooperation with The Weizmann Institute of Science. Contributors explore how the steroid receptor complex modulates transcription of RNA and cover topics ranging from the sequential acquisition of responsiveness to estrogen in the rat uterus to the ontogeny of steroid receptors in the guinea pig. This book is comprised of 29 chapters and begins with a review of estrogen and estrogen effects in rat uterus and pituitary in culture. The embryonic chick Müllerian duct and several fetal guinea pig organs are then considered, followed by discussions on mammalian and chick liver, multi-hormonal control in rat liver; progesterone and decidualization; and rat mammary gland in culture. Glucocorticoids in developing pancreas, lung, and liver are examined, along with ecdysteroids in both locusts and Drosophila. Refractoriness is exemplified by gonadotropin action in the ovary. The remaining chapters deal with the role of steroid hormone receptors in brain development; the neural trigger for ovulation; aromatization and development of responsiveness of the brain to gonadal steroids; and neuroendocrine correlates of female-offspring interaction in maternal rats. This monograph will be of value to physiologists, biologists, and biochemists.
Download or read book Advances in Rapid Sex Steroid Action written by Gabriella Castoria and published by Springer Science & Business Media. This book was released on 2011-12-15 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast and prostate cancers are both hormone-dependent, at least in some stages of their progression. Hormonal manipulation represents an important therapeutic approach. Although most of breast and prostate cancers initially respond to hormone therapy, most tumors reinitiate to growth. Finally, hormone-resistant and metastatic breast and prostate cancers may develop. Thus, the challenge is the dissection of mechanisms by which steroid receptor signaling pathways continue to influence cell growth and invasiveness. Compelling evidence indicates that steroid hormones elicit non-genomic responses in extra-nuclear compartment of target cells. In this cellular location, steroid-coupled receptors rapidly recruit signaling effectors or scaffold proteins and activate multiple pathways leading to proliferation, survival, migration and invasiveness. The immediate challenge is the dissection of key events regulating the steroid response of target tissues to prevent progression and improve treatment of breast and prostate cancers.
Download or read book Steroid Hormone Action written by Malcolm G. Parker and published by Irl Press. This book was released on 1993 with total page 210 pages. Available in PDF, EPUB and Kindle. Book excerpt: "As well as being important physiologically, steroid-responsive systems have been widely used as models for studying eukaryotic gene structure, action, and regulation. This volume is a comprehensive description of the molecular mechanisms by which steroid hormones regulate the expression of specific target genes. Topics covered in detail include the structure of steroid receptors, transcriptional activation and repression, steroid binding proteins, and steroidogenesis." "Steroid Hormone Action is an up-to-date text, written by international experts, which brings together the most important recent advances in this field. It is a superb guide for molecular biologists, pharmacologists, and clinicians interested in gene regulation, hormones and steroid antagonists, and endocrine-related disorders."--BOOK JACKET.Title Summary field provided by Blackwell North America, Inc. All Rights Reserved
Download or read book Steroid Hormone Action and Cancer written by K. Menon and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 231 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is an outgrowth of a symposium held at the University of Michigan, Ann Arbor, Michigan, October 27-29, 1975. This symposium was organized to bring together basic scientists and clinicians for the purpose of exchanging new ideas and the latest information in the area of Steroid Hormone Action and Cancer. The design of the symposium included both formal plenary sessions and informal roundtable discussion groups, the chapters of this volume being drawn primarily from these proceedings. During the last quarter of a century considerable progress has been made toward understanding the molecular mechanisms in volved in steroid hormone action. It now appears that the mechan sim of action of the four major classes of steroid hormones is qualitatively similar. Research during the past decade has demonstrated steroid hormone receptors in a variety of normal and neoplastic tissues. Receptor-containing neoplasms have been shown to be hormone-dependent and undergo regression when treated with hormone antagonists. Natural and synthetic steroids also have been employed for many years to successfully treat various types of cancer, for example: estrogens, androgens and progestagens for breast cancer; estrogens and progestagens for prostatic carcinoma; progestagens for endometrial carcinoma; and corticoids for leu kemias. All of these neoplasms have now been found to possess receptors for the steroids empirically used in their treatment.
Download or read book Steroid Hormone Action written by Malcolm G. Parker and published by IRL Press. This book was released on 1993 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: Steroid Hormone Action is a comprehensive overview of the molecular mechanisms by which these hormones regulate the expression of specific target genes. The book covers the structure of steroid receptors, transcriptional activation and repression, and also contains chapters on steroid bindingproteins and steroidogenesis. Steroid receptors represent one of the best characterized transcription factors so that the book will be of general interest to Molecular Biologists studying eucaryotic gene regulation. Chapters on the mechanisms of action of steoid antagonists and defective receptorsin target cells will be of particular interest to Endocrinologists and Clinicians. In such a rapidly progressing field it is difficult to keep up with all the literature but this book, written by international experts, focuses on the most important advances that have been made recently.
Download or read book Recent Advances in Glucocorticoid Receptor Action written by A. Cato and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: The long-term use of glucocorticoids is associated with several deleterious effects. Attempts to separate the beneficial from the adverse effects of these compounds have met with varying degrees of difficulty. The discovery of distinct modes of action of the glucocorticoid receptor, the protein that mediates glucocorticoid action has opened up many possibilities for improving glucocorticoid therapy. This book provides an in-depth overview of the molecular actions of the glucocorticoid receptor and discusses the chances of an imminent identification of selective glucocorticoid agonists. Such componds should fulfill all the criteria of a glucocorticoid but should lack the sideeffects so far linked with classical glucocorticoids.
Download or read book Schering Symposium on Biodynamics and Mechanism of Action of Steroid Hormones Berlin March 14 to 16 1968 written by Gerhard Raspé and published by Elsevier. This book was released on 2013-10-22 with total page 365 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Biosciences 2 documents the proceedings of the Schering Symposium on Biodynamics and Mechanism of Action of Steroid Hormones held in Berlin, on 14-16 March 1968. The volume begins by presenting the opening address on the symposium's main themes followed by a lecture on the factors influencing the nature and significance of research in the biological sciences. The papers presented cover topics such as methods for automatic and semi-automatic assay of steroids; the combination of gas chromatography and mass spectrometry for the investigation of complex mixtures; factors controlling steroid hormone metabolism; and the metabolism of free and conjugated estrogens. Other studies deal with the molecular basis of estrogen-binding in target cells; early biochemical events in the mouse testis associated with ultimate induction of interstitial cell tumors by estrogens; biochemical features of androgens; and effects of corticosteroid administration on rats. This book also presents panel discussions on the clinical aspects, biodynamics, and action of steroid hormones.
Download or read book Molecular Mechanism of Steroid Hormone Action written by Virinder K. Moudgil and published by de Gruyter. This book was released on 1985 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Rapid Sex Steroid Action written by Gabriella Castoria and published by Springer. This book was released on 2011-12-14 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Breast and prostate cancers are both hormone-dependent, at least in some stages of their progression. Hormonal manipulation represents an important therapeutic approach. Although most of breast and prostate cancers initially respond to hormone therapy, most tumors reinitiate to growth. Finally, hormone-resistant and metastatic breast and prostate cancers may develop. Thus, the challenge is the dissection of mechanisms by which steroid receptor signaling pathways continue to influence cell growth and invasiveness. Compelling evidence indicates that steroid hormones elicit non-genomic responses in extra-nuclear compartment of target cells. In this cellular location, steroid-coupled receptors rapidly recruit signaling effectors or scaffold proteins and activate multiple pathways leading to proliferation, survival, migration and invasiveness. The immediate challenge is the dissection of key events regulating the steroid response of target tissues to prevent progression and improve treatment of breast and prostate cancers.
Download or read book An Introduction to Neuroendocrinology written by Richard E. Brown and published by Cambridge University Press. This book was released on 1994-01-27 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed as an introductory text in neuroendocrinology; the study of the interaction between the brain and endocrine system and the influence of this on behaviour. The endocrine glands, pituitary gland and hypothalamus and their interactions and hormones are discussed. The action of steroid and thyroid hormone receptors and the regulation of target cell response to hormones is examined. The function of neuropeptides is discussed with respect to the neuroendocrine system and behaviour. The neuroimmune system and lymphokines are described and the interaction between the neuroendocrine and neuroimmune systems discussed. Finally, methods for studying hormonal influences on behaviour are outlined. Each chapter has review and essay questions designed for advanced students and honours or graduate students with a background in neuroscience, respectively.
