Download or read book Reactive Species Manipulations Toward Desired Outcomes In Biological Systems written by G K Suraishkumar and published by World Scientific. This book was released on 2024-05-28 with total page 187 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fine balance in reactive species (RS) levels inside the cell, or redox homeostasis, is crucial for normal life. RS are molecules such as hydroxyl, superoxide, and others whose reaction rates are typically high. Further, RS are now accepted as the molecular mediators of stresses on cells. RS are also implicated in many diseases including cancer, cardiovascular diseases, and neurodegenerative diseases.In contrast to the popular view that RS are deleterious, this book discusses desirable outcomes from the manipulation of reactive species levels in the cells. The discoveries include a fundamental approach to overcome major limitations with traditional oxygen supply to bioreactors, a mere treatment of the inoculum to significantly (sometimes many-fold) increase productivity of bio-oil, enzymes, and other products from bioprocesses, unexpected effect of shear on cultivated cells, rhythms in intracellular reactive species levels and resetting the rhythm to significantly improve cancer drug efficiency.The book concludes with a description of a scalable reactive species module — one that can be integrated with any genome scale model to gain significant insights into the RS effects on metabolism.
Download or read book Reactive Oxygen Species ROS Nanoparticles and Endoplasmic Reticulum ER Stress Induced Cell Death Mechanisms written by Loutfy H. Madkour and published by Academic Press. This book was released on 2020-06-27 with total page 782 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms presents the role of ROS?mediated pathways cellular signaling stress, endoplasmic reticulum (ER) stress, oxidative stress, oxidative damage, nanomaterials, and the mechanisms by which metalloids and nanoparticles induce their toxic effects. The book covers the ecotoxicology of environmental heavy metal ions and free radicals on macromolecules cells organisms, heavy metals?induced cell responses, oxidative stress, the source of oxidants, and the roles of ROS, oxidative stress and oxidative damage mechanisms. It also examines the nanotoxicity, cytotoxicity and genotoxicity mechanisms of nanomaterials and the effects of nanoparticle interactions. Antioxidant defense therapy and strategies for treatment round out the book, making it an ideal resource for researchers and professional scientists in toxicology, environmental chemistry, environmental science, nanomaterials and the pharmaceutical sciences. - Covers the ecotoxicology of environmental heavy metal ions and the interactions between specific heavy metals?induced cell responses and oxidative stress - Provides a better understanding of the mechanism of nanomaterial-induced toxicity as a first defense for hazard prevention - Covers recent advances in new nanomedication technologies for the effects of NPs on oxidative stress, ROS and ER stress - Discusses the effects of interactions between antioxidant defense therapy, ROS and strategies for treatment
Download or read book Targeted Metallo Drugs written by Etelka Farkas and published by CRC Press. This book was released on 2023-05-15 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Volume 24, entitled Targeted Metallo-Drugs: Design, Development, and Modes of Action, of the series Metal Ions in Life Sciences (MILS), fosters inter-disciplinary research in the vibrant field of Biological Inorganic Chemistry. Inspired by the clinical success of cisplatin as a leading anticancer drug but mindful of the shortcomings associated with its use including dose-limiting toxic side effects and acquired or intrinsic drug resistance, scientists across the globe have been endeavoring to identify new metallo-drugs for therapeutic exploitation. This has led to innovative metallo-drug candidates that (i) enhance cancer cell selectivity, thus reducing toxic side effects, and/or (ii) possess new modes of action to improve efficacy and also target resistance pathways. This and more are captured in MILS- 24 which consists of 12 comprehensive, well-illustrated, and up to date chapters with over 1600 citations, 100 figures, and 10 tables with key contributions from 32 international experts from Europe, Asia, and North and South America. MILS- 24 not only keeps the scientific community abreast of latest developments, it also serves as an invaluable resource to stimulate further research on targeted metallo-drug design and development. It covers anticancer, antimicrobial, antiviral, and other agents, such as those targeting tropical diseases and cyanide poisoning and radiometals in molecular imaging and therapy It highlights recent metallo-drug developments targeting COVID-19 It features advanced spectroscopic methods and metallomics as important tools to elucidate the modes of actions of metallo-drugs
Download or read book Coulson and Richardson s Chemical Engineering written by Sohrab Rohani and published by Butterworth-Heinemann. This book was released on 2017-08-23 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coulson and Richardson's Chemical Engineering: Volume 3B: Process Control, Fourth Edition, covers reactor design, flow modeling, and gas-liquid and gas-solid reactions and reactors. - Converted from textbooks into fully revised reference material - Content ranges from foundational through to technical - Added emerging applications, numerical methods and computational tools
Download or read book Nitric Oxide and Hydrogen Peroxide Signaling in Higher Plants written by Dharmendra K. Gupta and published by Springer. This book was released on 2019-03-28 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes nitric oxide (NO) and hydrogen peroxide (H2O2) functions in higher plants. Much progress has been made in the field of NO and H2O2 research regarding the various mechanisms and functions of these two molecules, particularly regarding stress tolerance and signaling processes, but there are still gaps to be filled. NO and H2O2 are both crucial regulators of development, and act as signaling molecules at each step of the plant lifecycle, while also playing important roles in biotic and abiotic responses to environmental cues. The book summarizes key advances in the field of NO and H2O2 research, focusing on a range of processes including: signaling, metabolism, seed germination, development, sexual reproduction, fruit ripening, and defense.
Download or read book Progress in Colloid and Surface Science Research written by Emelio A. Scarpetti and published by Nova Publishers. This book was released on 2007 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents leading-edge research on colloids and surface science and spans a wide range of topics including biological interactions at surfaces, molecular assembly of selective surfaces, role of surface chemistry in microelectronics and catalysis, tribology, and colloidal physics in the context of crystallisation and suspensions; fluid interfaces; adsorption; surface aspects of catalysis; dispersion preparation, characterisation and stability; aerosols, foams and emulsions; surfaces forces; micelles and microemulsions; light scattering and spectroscopy; nanoparticles; new material science; detergency and wetting; thin films, liquid membranes and bilayers; surfactant science; polymer colloids; rheology of colloidal and disperse systems; electrical phenomena in interfacial and disperse systems.
Download or read book The Science and Applications of Synthetic and Systems Biology written by Institute of Medicine and published by National Academies Press. This book was released on 2011-12-30 with total page 570 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.
Download or read book A New Biology for the 21st Century written by National Research Council and published by National Academies Press. This book was released on 2009-11-20 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now more than ever, biology has the potential to contribute practical solutions to many of the major challenges confronting the United States and the world. A New Biology for the 21st Century recommends that a "New Biology" approach-one that depends on greater integration within biology, and closer collaboration with physical, computational, and earth scientists, mathematicians and engineers-be used to find solutions to four key societal needs: sustainable food production, ecosystem restoration, optimized biofuel production, and improvement in human health. The approach calls for a coordinated effort to leverage resources across the federal, private, and academic sectors to help meet challenges and improve the return on life science research in general.
Download or read book MEDICAL AND HEALTH SCIENCES Volume XII written by Osmo Otto Paivio Hanninen; Mustafa Atalay; B.P. Mansourian; A. Wojtezak; S.M. Mahfouz; Harry Majewski; Elaine Elisabetsky; Nina L. Etkin; Ralph Kirby; T.G. Downing and M.I. El Gohary and published by EOLSS Publications. This book was released on 2010-10-12 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical and Health Sciences is a component of Encyclopedia of Biological, Physiological and Health Sciences in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. These volume set contains several chapters, each of size 5000-30000 words, with perspectives, applications and extensive illustrations. It carries state-of-the-art knowledge in the fields of Medical and Health Sciences and is aimed, by virtue of the several applications, at the following five major target audiences: University and College Students, Educators, Professional Practitioners, Research Personnel and Policy Analysts, Managers, and Decision Makers and NGOs.
Download or read book Pharmacology Volume II written by Harry Majewski and published by EOLSS Publications. This book was released on 2009-10-29 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacology is a component of Encyclopedia of Biological, Physiological and Health Sciences in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. Pharmacology is the study of the actions of chemicals on the body and most usually it is defined as chemicals that can have a therapeutic action to treat disease. Since it looks at the interaction between chemicals and body systems pharmacology utilizes the basic disciplines of chemistry, biochemistry, physiology, pathology and microbiology in its practice. Pharmacology is a foundation science for pharmacy which is the rational prescribing of drugs to treat disease and the foundation science for toxicology which is the study of the toxic actions of chemicals on the body. The two volumes are organized in groups of chapters as follows: The first group of chapters discuss pharmacological principles and these include chapters on Pharmacodynamics; Pharmacokinetics, Neuropharmacology, Autonomic Pharmacology and Clinical Pharmacology. The second group of chapters discusses the processes of Drug discovery and the Safety requirements for drugs to be used therapeutically and include Drug Discovery and Safety Pharmacology assessment. The largest group of chapters discuss different therapeutic areas and include Cardiovascular and renal pharmacology; Endocrine pharmacology; Neuropsychopharmacology; Pulmonary Pharmacology; Gastrointestinal pharmacology; Poisons venoms and toxins; Drugs on skeletal muscle; the Pharmacotherapy of inflammation; Reproductive pharmacology; Pain pharmacology and analgesia. The final group of chapters discuss new approaches and include Pharmacogenetics and pharmacogenomics; Immunopharmacology and Gene therapy. These two volumes are aimed at the following a wide spectrum of audiences from the merely curious to those seeking in-depth knowledge: University and College students Educators, Professional practitioners, Research personnel and Policy analysts, managers, and decision makers and NGOs.
Download or read book Biofuel s Engineering Process Technology written by Marco Aurelio Dos Santos Bernardes and published by BoD – Books on Demand. This book was released on 2011-08-01 with total page 746 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book aspires to be a comprehensive summary of current biofuels issues and thereby contribute to the understanding of this important topic. Readers will find themes including biofuels development efforts, their implications for the food industry, current and future biofuels crops, the successful Brazilian ethanol program, insights of the first, second, third and fourth biofuel generations, advanced biofuel production techniques, related waste treatment, emissions and environmental impacts, water consumption, produced allergens and toxins. Additionally, the biofuel policy discussion is expected to be continuing in the foreseeable future and the reading of the biofuels features dealt with in this book, are recommended for anyone interested in understanding this diverse and developing theme.
Download or read book Towards Autonomous Robotic Systems written by Roderich Groß and published by Springer Science & Business Media. This book was released on 2011-08-19 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 12th Annual Conference Towards Autonomous Robotics Systems, TAROS 2011, held in Sheffield, UK, in August/September 2011. The 32 revised full papers presented together with 29 two-page abstracts were carefully reviewed and selected from 94 submissions. Among the topics addressed are robot navigation, robot learning, human-robot interaction, robot control, mobile robots, reinforcement learning, robot vehicles, swarm robotic systems, etc.
Download or read book Biodefense in the Age of Synthetic Biology written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-01-05 with total page 189 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.
Download or read book Social Psychology written by Thomas Heinzen and published by SAGE Publications, Incorporated. This book was released on 2020-10-15 with total page 561 pages. Available in PDF, EPUB and Kindle. Book excerpt: This award-winning text invites students to discover social psychology’s relevance to their lives. Authors Thomas Heinzen and Wind Goodfriend capture student interest by weaving stories drawn from their own personal experiences with compelling examples from everyday life, all carefully placed in historical context. Social psychology is presented as an evolving, science-driven conversation; chapters build on core questions central to scientific inquiry, while a methods-in-context approach cultivates psychological literacy. The Second Edition has been thoroughly updated with new pop culture examples, additional diversity coverage, recent controversies related to the Zimbardo and Milgram studies, and over a hundred new citations from the latest research. This title is accompanied by a complete teaching and learning package. Contact your SAGE representative to request a demo. Digital Option / Courseware SAGE Vantage is an intuitive digital platform that delivers this text’s content and course materials in a learning experience that offers auto-graded assignments and interactive multimedia tools, all carefully designed to ignite student engagement and drive critical thinking. Built with you and your students in mind, it offers simple course set-up and enables students to better prepare for class. Learn more. Assignable Video with Assessment Assignable video (available with SAGE Vantage) is tied to learning objectives and curated exclusively for this text to bring concepts to life. Watch a sample video on false memories. Assignable Self-Assessments Assignable and interactive self-assessments (available with SAGE Vantage) help students experience social psychology in a deeper, more memorable way that reinforces learning. LMS Cartridge: Import this title’s instructor resources into your school’s learning management system (LMS) and save time. Don’t use an LMS? You can still access all of the same online resources for this title via the password-protected Instructor Resource Site. Learn more. Also of Interest Case Studies for Teaching Social Psychology, Second Edition, also by Heinzen and Goodfriend, uses brief, entertaining real-world stories to illustrate the historical context and evolution of major theories within the field of social psychology. Bundle Case Studies for Teaching Social Psychology, Second Edition with Social Psychology, Second Edition for even more savings.
Download or read book Energy Research Abstracts written by and published by . This book was released on 1984 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Agricultural Chemistry Biotechnology written by and published by . This book was released on 1999 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Translational Insights Into Pancreatic Ductal Adenocarcinoma written by Peter Bailey and published by Frontiers Media SA. This book was released on 2022-04-26 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:
