Download or read book RAPPORT SUR L ETAT ET LES TENDANCES DE LA TOXICOLOGIE IN VITRO ET MODIFICATIONS DES METHODOLOGIES POUR REDUIRE L EXPERIMENTATION ANIMALE written by and published by . This book was released on 1990 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Rapport sur l tat et les tendances de la toxicologie in vitro et modifications des m thodologies pour r duire l exp rimentation animale written by and published by . This book was released on 1990 with total page 225 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book In Vitro Toxicology A Progress Report from the Johns Hopkins Center for Alternatives to Animal Testing Volume 3 written by AM Goldberg (Ed) and published by . This book was released on 1985 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Rapport Sur L tat Et Les Tendances de la Toxicologie in Vitro Et Modifications Des M thodologies Pour R duire L exp rimentation Animale written by J. P. W. Gilman and published by Division de la toxicologie des médicaments, Bureau de recherche sur les médicaments, Santé et bien-être social Canada. This book was released on 1991 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: The primary purposes of toxicological testing are the protection of human health and the safeguarding of the environment from excessive manmade contamination. Responsibility for setting safety standards and monitoring their implementation lies mainly with the federal departments of health, agriculture, and the environment. This report discusses in some detail the state-of-the-art of in vitro toxicology and other trends in alternative toxicological testing that may lead to a reduction in the use of animals for these purposes. It covers both the national and international fields, particularly in pharmaceuticals and biologicals. The toxicological testing of consumer chemicals, agricultural chemicals, and foods is also considered in less detail. The report focuses on Canada and the testing R & D undertaken in this country.
Download or read book In Vitro Methods in Developmental Toxicology written by Gary L. Kimmel and published by CRC Press. This book was released on 1989-11-30 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text brings together the work of several investigators who used in vitro techniques to probe the nature of embryonic cell response to a diverse group of chemical agents. It focuses on the approaches, limitations, usefulness and applicability of defining mechanisms underlying altered development. This work includes discussions on pharmacodynamic principles and placental transfer mechanisms. It also examines the potential for in vitro systems to serve as an adjunct to the risk assessment process. Ideal for both the layman and the expert in this area, this volume provides a general understanding of the types of approaches that can be used and specific approaches in investigating altered development.
Download or read book In Vitro Toxicology Mechanisms and New Technology Volume 8 written by DE. Amacher and published by . This book was released on 1991 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Essai N 417 written by Organisation de coopération et de développement Économiques and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book In Vitro Toxicology New Directions Volume7 written by AM Goldberg (Ed) and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: In Vitro Approaches to Drug Discovery; Use of In Vitro Assays to Define the Malignant Activities of Tumor Cells and to Screen for Antimetastatic Drugs; Development of Alternatives in a Consumer Product Company; In Vitro Neurotoxicity in Drug Discovery and Development; Analysis of Cell Type Specific Neurotoxicity Using Purified Cultures of Avian and Mammalian Retinal Neurons and Photoreceptors; Whole Cell Patch Clamp Recordings of the Responses of Cultured Rabbit Trigeminal Ganglion Neurons to Capsaicin, An Irritant and Neurotoxin; Neurotoxicity of Dopamine Selective Drugs; In Vitro Neurotoxicity Testing of Cancer Chemotherapeutic Agents Using Cerebellar Explant Cultures; Permanent Differentiated Cell Lines from Human Biopsy Material; Toxicology, In Vitro Methods, and Alternatives; The Development of Insulin Assays Without the Use of Animals; An Introduction to the Immune System; In Vitro Analysis of Chemical Toxicity Directed Toward Bone Marrow Derived Macrophages and Stromal Cells, The Impact on B-Cell Lymphopoiesis; Characterization of In Vivo and In Vitro Chemical Exposure and Immunization Approaches for Assessing Effects on Acquired Immunity; Comparisons of the Cytotoxicities of Dermatotoxicants to Human Keratinocytes and Fibroblasts in Vitro; Flow Cytometric Analysis of Toxicity by Alkylating Agents in Human Epidermal Keratinocytes; Developing an Alternative to the Draize Skin Test, Comparison of Human Skin Cell Responses to Irritants In Vitro; A Physiological Skin Model for In Vitro Toxicity Studies; Evaluation of Various Parameters in Testing Drug Cytotoxicity in Primary Hepatocyte Cultures; Development of a Juvenile Catfish (Ictalurus punctatus) Primary Hepatocyte, Culture for Aquatic Toxicity Testing; Cytotoxic Response of Juvenile Catfish (Ictalurus punctatus) Primary Hepatocytes to Cadmium; Cytotoxic and Post Isolation Recovery Time Responses of Juvenile Catfish (Ictalurus punctatus) Primary Hepatocytes to Mercury Chloride; Hepatocyte Cocultures as a Model for the Study of Long Term, Selective, and Reversible Toxic Effects of Drugs; The Liver Slice System, A Simple Acute Toxicity Test for Evaluation of Hepatotoxic Agents; In Vitro Assays for Chemicals and Drugs Causing Immunomodulation in Fish; Suspended Nylon Screen Long Term Bone Marrow Cultures as Substrates for Cytotoxicity Determinations; Flow Cytometric Analysis of Peripheral Blood Lymphocytes for the Assessment of Toxicity by Alkylating Agents; Assessing the Eye Irritation Potential of Surfactant Based Materials Using the Chorioallantoic Membrane Vascular Assay; Validation Study, Ocular Irritancy Prediction with the Total Cell Protein, Uridine Uptake, and Neutral Red Assays Applied to Human Epidermal Keratinocytes and Mouse 3T3 Cells; Evaluation of an Alternative Method for Ocular Irritation; Evaluation of the Neutral Red Cytotoxicity Assay as a Predictive Test for the Ocular Irritancy Potential of Cosmetic Products; Proteoglycan and Procollagen Syntheses in Rat Embryo Limb Bud Cultures Treated with Quinolone Antibacterials; Primary Hepatocyte Culture as an Activating System for Xenobiotica Tested in the Rat Whole Embryo In Vitro; The Prediction of Phototoxic Potential Using Human A431 Cells and Mouse 3T3 Cells; Applications of the EYTEX Method for Determination of the Ocular Irritation of Surfactant Formulations; Toxicological Recognition of Replicate Casts; Isolation, Culture, and Characterization of Human Renal Papillary Collecting Duct Cells; Interlaboratory Validation Study of the Keratinocyte Neutral Red Bioassay from Clonetics Corporation.
Download or read book In Vitro Toxicology written by Alan M. Goldberg and published by . This book was released on 1985 with total page 748 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Progress in In Vitro Toxicology Volume 6 written by AM Goldberg (Ed) and published by . This book was released on 1988 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book In Vitro Methods in Developmental Toxicology written by Gary L. Kimmel and published by CRC Press. This book was released on 1989-11-30 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text brings together the work of several investigators who used in vitro techniques to probe the nature of embryonic cell response to a diverse group of chemical agents. It focuses on the approaches, limitations, usefulness and applicability of defining mechanisms underlying altered development. This work includes discussions on pharmacodynamic principles and placental transfer mechanisms. It also examines the potential for in vitro systems to serve as an adjunct to the risk assessment process. Ideal for both the layman and the expert in this area, this volume provides a general understanding of the types of approaches that can be used and specific approaches in investigating altered development.
