Download or read book Surface Enhanced Raman Spectroscopy written by Marek Prochazka and published by Springer. This book was released on 2015-12-12 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book gives an overview of recent developments in RS and SERS for sensing and biosensing considering also limitations, possibilities and prospects of this technique. Raman scattering (RS) is a widely used vibrational technique providing highly specific molecular spectral patterns. A severe limitation for the application of this spectroscopic technique lies in the low cross section of RS. Surface-enhanced Raman scattering (SERS) spectroscopy overcomes this problem by 6-11 orders of magnitude enhancement compared with the standard RS for molecules in the close vicinity of certain rough metal surfaces. Thus, SERS combines molecular fingerprint specificity with potential single-molecule sensitivity. Due to the recent development of new SERS-active substrates, labeling and derivatization chemistry as well as new instrumentations, SERS became a very promising tool for many varied applications, including bioanalytical studies and sensing. Both intrinsic and extrinsic SERS biosensing schemes have been employed to detect and identify small molecules, nucleic acids and proteins, and also for cellular and in vivo sensing.
Download or read book Raman and Surface Enhanced Raman of Biological Material written by and published by . This book was released on 2004 with total page 6 pages. Available in PDF, EPUB and Kindle. Book excerpt: In light of recent world events, an emphasis has been placed firmly on the development of rapid biological threat detection techniques for the military as well as for homeland security. Vibrational spectroscopic methods such as Raman and surface enhanced Raman scattering (SERS) provide rapid detailed fingerprint information about the molecular composition of biomaterial in a non-destructive manner. The technology and methodology to acquire and interpret biological Raman spectra has seen tremendous advances over the past several decades. The problem of tissue fluorescence, which overwhelms the Raman signal of most biological samples upon excitation in the visible region, has been largely overcome by instrumentation operating in the near-IR region of the spectrum. In addition, treatment of biomaterials with silver nanoparticles not only enhances the normal Raman signal by several orders of magnitude but also further reduces the fluorescence backgrounds via interaction between the analyte and the metal SERS substrate. This work presents a study into the applicability of qualitative Raman spectroscopy with principal component analysis (PCA) and surface enhanced Raman for quantitative analysis of the biological threat materials associated with the Rapid Agent Aerosol Detection (RAAD) project.
Download or read book Principles of Surface Enhanced Raman Spectroscopy written by Eric Le Ru and published by Elsevier. This book was released on 2008-11-17 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt: SERS was discovered in the 1970s and has since grown enormously in breadth, depth, and understanding. One of the major characteristics of SERS is its interdisciplinary nature: it lies at the boundary between physics, chemistry, colloid science, plasmonics, nanotechnology, and biology. By their very nature, it is impossible to find a textbook that will summarize the principles needed for SERS of these rather dissimilar and disconnected topics. Although a basic understanding of these topics is necessary for research projects in SERS with all its many aspects and applications, they are seldom touched upon as a coherent unit during most undergraduate studies in physics or chemistry. This book intends to fill this existing gap in the literature. It provides an overview of the underlying principles of SERS, from the fundamental understanding of the effect to its potential applications. It is aimed primarily at newcomers to the field, graduate students, researchers or scientists, attracted by the many applications of SERS and plasmonics or its basic science. The emphasis is on concepts and background material for SERS, such as Raman spectroscopy, the physics of plasmons, or colloid science, all of them introduced within the context of SERS, and from where the more specialized literature can be followed. Represents one of very few books fully dedicated to the topic of surface-enhanced Raman spectroscopy (SERS) Gives a comprehensive summary of the underlying physical concepts around SERS Provides a detailed analysis of plasmons and plasmonics
Download or read book Surface Enhanced Raman Scattering New Theoretical Approaches Materials and Strategies written by Ivano Alessandri and published by Frontiers Media SA. This book was released on 2020-03-25 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Principles and Clinical Diagnostic Applications of Surface Enhanced Raman Spectroscopy written by Yuling Wang and published by Elsevier. This book was released on 2021-02-15 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Clinical Diagnostic Applications of Surface-Enhanced Raman Spectroscopy summaries the principles of SERS and nanoplasmonic materials for SERS, with a focus on applications in clinical diagnostics. This book covers the fundamentals of SERS, materials, experimental aspects and applications of SERS in clinical diagnostics, with discussions on label-free/direct SERS assay, design and synthesis of SERS nanotags, SERS nanotags for point-of-care diagnostics, microfluidic SERS assay, and in vitro and in vivo sensing and imaging. Written by subject experts, this comprehensive volume showcases recent progress in SERS applications in clinical diagnostics, thus helping readers understand when and how to use SERS in a clinical setting. Introduces the basics of SERS/SERS nanotags and suitable nanomaterials for SERS applications Gives an overview on the cutting-edge research on SERS applications for clinical diagnosis, including the latest advances in our understanding of underlying principles to enable material design and clinical applications Gradually builds from the fundamental concepts to the applications of SERS for clinical diagnostics
Download or read book Bacteria Classification Via Surface Enhanced Raman Spectroscopy and Principal Component Analysis written by and published by . This book was released on 2006 with total page 7 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface-enhanced Raman scattering (SERS) provides rapid fingerprinting of biomaterial in a non-destructive manner. The adsorption of colloidal silver to biological material suppresses native biofluorescence while increasing the normal Raman signal via the surface-enhanced Raman effect. This work validates the applicability of qualitative SER spectroscopy, utilizing principal component analysis (PCA) to show discrimination of biological threat simulants, based upon multivariate statistical confidences limits bounding known data clusters. Several strains of Bacillus spores are investigated along with Pantoea agglomerans, and Brucella noetomae.
Download or read book Surface Enhanced Raman Spectroscopy Biosensing and Diagnostic Technique for Healthcare Applications written by Swati Jain and published by Bentham Science Publishers. This book was released on 2021-12-28 with total page 263 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface enhanced Raman spectroscopy (SERS) is a technique applied in multidisciplinary research. Its use has tremendously grown in the last 40 years owing to improved nanofabrication, biomolecules extraction and sensitive signal acquisition techniques. This book focuses on the underlying principles of SERS by emphasizing on basic concepts and background information about the subject. Chapters explain the physics of Raman spectroscopy while also indicating its relevance to designing protocols and methodologies for biosensing and imaging. The book gives updated and recent details on colloids and nanostructures, their fabrication, surface engineering and immobilization methods, all in context to SERS based biosensing. Key Features: - Covers basic knowledge and new research about surface enhanced Raman spectroscopy (SERS) - Provides a complete framework on SERS based biosensing with concise chapters - Focuses on different active molecules critical to SERS and associated developed nanoassemblies - Presents information about ongoing research on SERS imaging applications - Highlights bottlenecks of SERS technique in biosensing - Includes references for further reading This book serves as a reference book for researchers and academicians and will also provide a reasonable understanding on the topic of SERS to newcomers irrespective of their background in a simple manner. The book is of interest to all readers within the scientific community involved with Raman spectroscopy, including chemists, physicists, biologists, material scientists as well as biomedical engineers.
Download or read book Surface Enhanced Raman Scattering SERS from Evanescent Wave Coupled Microcavity Applied to Simple Chemical and Biological Materials written by Gyoungil Lee and published by . This book was released on 2012 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Frontiers of Surface Enhanced Raman Scattering written by Yukihiro Ozaki and published by John Wiley & Sons. This book was released on 2014-02-19 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive presentation of Surface-Enhanced Raman Scattering (SERS) theory, substrate fabrication, applications of SERS to biosystems, chemical analysis, sensing and fundamental innovation through experimentation. Written by internationally recognized editors and contributors. Relevant to all those within the scientific community dealing with Raman Spectroscopy, i.e. physicists, chemists, biologists, material scientists, physicians and biomedical scientists. SERS applications are widely expanding and the technology is now used in the field of nanotechnologies, applications to biosystems, nonosensors, nanoimaging and nanoscience.
Download or read book Surface Enhanced Vibrational Spectroscopy written by Ricardo Aroca and published by John Wiley & Sons. This book was released on 2006-05-01 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface Enhanced Vibrational Spectroscopy (SEVS) has reached maturity as an analytical technique, but until now there has been no single work that describes the theory and experiments of SEVS. This book combines the two important techniques of surface-enhanced Raman scattering (SERS) and surface-enhanced infrared (SEIR) into one text that serves as the definitive resource on SEVS. Discusses both the theory and the applications of SEVS and provides an up-to-date study of the state of the art Offers interpretations of SEVS spectra for practicing analysts Discusses interpretation of SEVS spectra, which can often be very different to the non-enhanced spectrum - aids the practicing analyst
Download or read book Infrared and Raman Spectroscopy of Biological Materials written by Hans-Ulrich Gremlich and published by CRC Press. This book was released on 2000-09-25 with total page 602 pages. Available in PDF, EPUB and Kindle. Book excerpt: Infrared and Raman Spectroscopy of Biological Materials facilitates a comprehensive and through understanding of the latest developments in vibrational spectroscopy. It contains explains key breakthroughs in the methodologies and techniques for infrared, near-infrared, and Raman spectroscopy. Topics include qualitative and quantitative analysis, bi
Download or read book Surface Enhanced Raman Scattering written by Zhong-Qun Tian and published by John Wiley & Sons Incorporated. This book was released on 2010-06-14 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: Surface-Enhanced Raman Spectroscopy: Principles, Experiments, and Applications is a comprehensive, up to date, and balanced treatment of the theoretical and practical aspects of Surface-Enhanced Raman Scattering (SERS), a useful branch of spectroscopy for several areas of science. This book describes the basic principles of SERS, including SERS mechanisms, performing SERS measurements, and interpreting data. Also emphasized are applications in electrochemistry; catalysis; surface processing and corrosion; Self-Assemble-Layer and L-B Films; polymer science; biology; medicine and drug analysis; sensors; fuel cells; forensics; and archaeology. It is an essential guide for student and professional analytical chemists.
Download or read book Applications of Raman Spectroscopy to Biology written by M. Ghomi and published by IOS Press. This book was released on 2012-02-23 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Raman spectroscopy has been known and used as a technique for 80 years, originally for the study of inorganic substances. Recent advances in underlying technology, such as lasers, detectors, filters and components, have transformed the technique into a very effective modern tool for studying complex biological problems. Professor Mahmoud Ghomi (of the University of Paris XIII) has edited this book on the applications of Raman spectroscopy to biology, covering in a readily accessible way the area from basic studies to the diagnosis of disease. The early chapters provide background information on basic principles underlying the main Raman methods covered in the book, with information on Surface-Enhanced Raman Scattering (SERS) and Surface-Enhanced Fluorescence (SEF), as well as giving accounts of applications to biomolecular and cellular investigations. Among the topics covered are studies of drugs and their complexes with biomolecules on nanoparticles, application of SERS to blood analysis, studies of single cells and of applications to human cancer diagnostics.This will be a useful book for experimental scientists in academic, governmental, industrial and clinical environments and for those entering the field of biomolecular spectroscopy.
Download or read book Surface Enhanced Raman Scattering written by Richard Chang and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the course of the development of surface science, advances have been identified with the introduction of new diagnostic probes for analytical characterization of the adsorbates and microscopic structure of surfaces and interfaces. Among the most recently de veloped techniques, and one around which a storm of controversy has developed, is what has now been earmarked as surface enhanced Raman scattering (SERS). Within this phenomenon, molecules adsorbed onto metal surfaces under certain conditions exhibit an anomalously large interaction cross section for the Raman effect. This makes it possible to observe the detailed vibrational signature of the adsorbate in the ambient phase with an energy resolution much higher than that which is presently available in electron energy loss spectroscopy and when the surface is in contact with a much larger amount of material than that which can be tolerated in infrared absorption experiments. The ability to perform vibrational spectroscopy under these conditions would lead to a new understanding about the chemical identity, geome try, and bonding of adsorbed material at a level previously unacces sible. It is for these reasons that the last few years have brought an explosion of activity surrounding the exploitation of SERS. The search for the origines) of the anomalous enhancement has given rise to a research sub-activity of its own. Efforts to explain the en hancement have led to an increased understanding of the whole range of phenomena associated with the interaction of photons with adsor bates and metal surfaces.
Download or read book Tip Enhancement written by and published by Elsevier. This book was released on 2011-09-22 with total page 339 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book discusses the recent advances in the area of near-field Raman scattering, mainly focusing on tip-enhanced and surface-enhanced Raman scattering. Some of the key features covered here are the optical structuring and manipulations, single molecule sensitivity, analysis of single-walled carbon nanotubes, and analytic applications in chemistry, biology and material sciences. This book also discusses the plasmonic materials for better enhancement, and optical antennas. Further, near-field microscopy based on second harmonic generation is also discussed. Chapters have been written by some of the leading scientists in this field, who present some of their recent work in this field. ·Near-field Raman scattering·Tip-enhanced Raman spectroscopy·Surface-enhanced Raman spectroscopy·Nano-photonics·Nanoanalysis of Physical, chemical and biological materials beyond the diffraction limits·Single molecule detection
Download or read book Principles and Clinical Diagnostic Applications of Surface Enhanced Raman Spectroscopy written by Yuling Wang and published by Elsevier. This book was released on 2021-09-17 with total page 465 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles and Clinical Diagnostic Applications of Surface-Enhanced Raman Spectroscopy summarizes the principles of surface-enhanced Raman scattering/spectroscopy (SERS) and plasmonic nanomaterials for SERS, with a focus on SERS applications in clinical diagnostics. This book covers the key concepts from the fundamentals, materials, experimental aspects, and applications of SERS in clinical diagnostics with discussions on label-free/direct SERS assay, design and synthesis of SERS nanotags, SERS nanotags for point-of-care diagnostics, microfluidic SERS assay, and in vitro and in vivo sensing and imaging. Written by experts from around the world, this comprehensive volume showcases the recent progress of SERS applications in clinical diagnostics and helps readers understand when and how to use SERS in a clinical setting. Introduces the basics of SERS and suitable nanomaterials for SERS application Gives an overview of the cutting-edge research on SERS applications for clinical diagnosis, including the latest advances in our understanding of underlying principles to enable material design and clinical applications Gradually builds from the fundamental concepts to the applications of SERS for clinical diagnostics
Download or read book Application of Surface Enhanced Raman Spectroscopy to Biological Systems written by and published by . This book was released on 2013 with total page 125 pages. Available in PDF, EPUB and Kindle. Book excerpt:
