Download or read book Quinoline Based Heterocycles Synthesis And Biological Activities written by Amulrao Uttamrao Borse and published by Lulu.com. This book was released on with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Quinoline Heterocycles written by Rajesh Y B R D and published by . This book was released on 2019 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Among heterocyclic compounds, quinoline is a privileged scaffold that appears as an important construction motif for the development of new drugs. Quinoline nucleus is endowed with a variety of therapeutic activities, and new quinolone derivatives are known to be biologically active compounds possessing several pharmacological activities. Many new therapeutic agents have been developed by using quinoline nucleus. Hence, quinoline and its derivatives form an important class of heterocyclic compounds for the new drug development. Numerous synthetic routes have been developed for the synthesis of quinoline and its derivatives due to its wide range of biological and pharmacological activities. The article covers the synthesis as well as biological activities of quinoline derivatives such as antimalarial, anticancer, antibacterial, anthelmintic, antiviral, antifungal, anti-inflammatory, analgesic, cardiovascular, central nervous system, hypoglycemic, and miscellaneous activities.
Download or read book Synthesis Characterization and Biological Activities of Heterocycles written by Muthu Thangaraj and published by . This book was released on 2018 with total page 858 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Heterocycles written by B. P. Nandeshwarappa and published by . This book was released on 2020-06 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Synthesis of Bioactive Heterocycles Using 3 Acetyl Quinolines written by V. Vijayakumar and published by LAP Lambert Academic Publishing. This book was released on 2012-08 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quinoline heterocycles found to have diverse biological activities and 3-functionalised quinolines are important intermediates for the synthesis of various quinoline derivatives. 3-acetyl-4-hydroxy-quinolin-2(1H)-one and 6-chloro-3-acetyl-4-phenyl-2-methyl quinoline were chosen as intermediates for the synthesis of some novel quinoline derivatives. In particular, only a few methods are available for the synthesis of 3-acetyl-4-hydroxy-quinolin-2(1H)-one, which involve either two step or multistep reaction protocols. In the present work, a rapid, efficient and one pot procedure for the synthesis of 3-acetyl-4-hydroxy-quinolin-2(1H)-ones has been developed both by conventional and microwave assisted synthesis. The 3-acetyl quinolines were converted into chalcones which in turn converted to quinoline-3-yl pyrazolines and quinoline-3-yl isoxazolines and a few into 3-(2, 4-substitutedstyryl)isoxazolo[4,5-c]quinolin-4(5H)-ones. These compounds were explored for their anti-microbial and cyctotoxicity studies.
Download or read book Bioactive Heterocycles V written by Mahmud Tareq Hassan Khan and published by Springer. This book was released on 2007-09-26 with total page 342 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts
Download or read book Strategies for the Synthesis of Heterocycles and Their Applications written by Premlata Kumari and published by BoD – Books on Demand. This book was released on 2023-07-19 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterocycles are present in the molecular architecture of a wide variety of natural products and compounds with significant biological potency. The numerous heterocycles are employed as significant intermediates in the fields of synthetic organic chemistry, pharmaceuticals, and organic synthesis. This book summarizes the synthesis of different heterocycles using various synthetic methods, including green methods, and applications of heterocycles in various fields.
Download or read book Quinolines Benzofurans Occurrence Synthesis Biological Activity written by Anjali Gupta and published by LAP Lambert Academic Publishing. This book was released on 2014-05-30 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Acetoxy drug: Protein transacetylase catalyses the transfer of acetyl groups from acetylated polyphenolic peracetates (PAs) to the receptor proteins and modulates the activity of proteins and alters the effect of various enzymes like Glutathione S-transferase, NADPH Cytochrome c Reductase and Nitric Oxide Synthase (NOS). Accordingly, Polyphenolic acetates were found effective in the inhibition of ADP induced platelet aggregation, because of which, the acetoxy derivatives of several classes of polyphenols were found to be the substrates of TAase. Our group has synthesized a number of heterocyclic compounds e.g. benzofurans and quinolones etc. These compounds were screened for various biological activities e.g. antioxidant, antiplatelet aggregation, and antimicrobial activities.
Download or read book Design Synthesis and Biological Evaluation of Novel Quinoline based Molecules with Potential Anticancer Activity written by Zohreh Amoozgar and published by . This book was released on 2007 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Heterocycles in Natural Product Synthesis written by Krishna C. Majumdar and published by John Wiley & Sons. This book was released on 2011-06-15 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt: Filling a gap on the market, this handbook and ready reference is unique in its discussion of the usefulness of various heterocyclic systems in the synthesis of natural products. Clearly structured for easy access to the information, each chapter is devoted to a certain class of heterocycle, providing a tabular presentation of the natural products to be covered containing the particular heterocyclic ring system along with their biological profile, occurrence and most important physical properties, backed by the appropriate references. In addition, the application of the heterocyclic system to the synthesis of natural products ic covered in detail. Of great interest to organic, natural products, medicinal and biochemists, as well as those working in the pharmaceutical and agrochemical industry.
Download or read book Biological and Computational Synthesis of Heterocyclic Compounds written by Irshad Ahamed J and published by . This book was released on 2024-01-08 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological and Computational Synthesis of Heterocyclic Compounds" authored by Irshad Ahamed J is a comprehensive guide to the synthesis and characterization of various heterocyclic compounds and their derivatives. The book provides an in-depth analysis of the biological and computational aspects of the synthesis of these compounds, making it an essential read for students and researchers in the field of organic chemistry. The book covers various aspects of the synthesis process, including reaction mechanisms, reaction conditions, and yield optimization. It also delves into the characterization of the synthesized compounds through a range of spectroscopic techniques such as IR, NMR, and mass spectrometry. The book further explores the biological activities of these compounds, including their antiviral, antibacterial, and anticancer properties.The computational aspects of the synthesis of heterocyclic compounds are also covered in detail. The book highlights the importance of computational methods in the design and synthesis of these compounds, including the use of molecular modeling and computer-aided drug design. Overall, "Biological and Computational Synthesis of Heterocyclic Compounds" is a valuable resource for anyone interested in the synthesis and characterization of these important organic compounds. It provides a comprehensive overview of the synthesis and biological activities of these compounds, making it an ideal reference for students and researchers alike.
Download or read book Aqueous Mediated Synthesis written by Asit K. Chakraborti and published by Walter de Gruyter GmbH & Co KG. This book was released on 2024-02-19 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Bioactive Heterocycles written by K. L. Ameta and published by Nova Science Publishers. This book was released on 2013 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a critical and lucid account of various synthetic methodologies and biological activities of different sized bioactive heterocyclic compounds. In effect, this book imparts a great deal of comprehensive reviews about the chemistry and biology of selected groups of heterocycles and natural products including important pharmaceuticals as well as agrochemical pesticides in one handy project. Besides, this compendious effort encompasses different methods of synthesis and biological evaluation of heterocyclic compounds. The main purpose of this book is to share the recent advances and scope of Bioactive Heterocycles for the future avenues in the field. It has specifically been designed by keeping in mind the wide interests of individuals engaged in the design and synthesis of biologically active heterocyclic compounds as well as research scientists in academia and industry. The authors expect this book to be a standard reference in Universities and industrial libraries.
Download or read book The Synthesis and Biological Activity of Certain Quinoline Derivatives written by Nazir Hassim and published by . This book was released on 1992 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Quinazolinone and Quinazoline Derivatives written by Ali Gamal Al-kaf and published by BoD – Books on Demand. This book was released on 2020-05-06 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the problems with modern public health is target searching for new highly effective medicinal preparations. Among those medicinal preparations are the natural and synthetic origins of quinazolinone-4 derivatives. Quinazolinone derivatives are reported to be physiologically and pharmacologically active. They also exhibit a wide range of activities such as anticonvulsant, antiinflammatory, antifungal, antimalarial, and sedative properties. Some of these compounds are identified as drugs used as diuretics, vasodilators, and antihypertensive agents. Moreover, sulfonamide derivatives have been widely used as bacteriostatic agents. Prompted by the above-mentioned facts and in conjunction with our ongoing program on the utility of readily obtainable starting material for the synthesis of heterocyclic systems of biological interest, we have decided to synthesize a series of quinazolinone derivatives having sulfonamide moiety with a potentially wide spectrum of biological responses.
Download or read book The Treatment of Incurable Diseases written by Howard Frederick Johnson and published by . This book was released on 1851 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Isocyanide based Multicomponent Reactions written by Jonathan G. Rudick and published by Frontiers Media SA. This book was released on 2020-02-20 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
