Download or read book A Guide to Sample Size for Animal based Studies written by Penny S. Reynolds and published by John Wiley & Sons. This book was released on 2023-12-11 with total page 294 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understand a foundational area of experimental design with this innovative reference Animal-based research is an essential part of basic and preclinical research, but poses a unique set of experimental design challenges. The most important of these are the 3Rs Replacement, Reduction and Refinement the principles comprising the ethical framework for humane animal-based studies. However, many researchers have difficulty navigating the design trade-offs necessary to simultaneously minimize animal use, and produce scientific information that is both rigorous and reliable. A Guide to Sample Size for Animal-Based Studies meets this need with a thorough, accessible reference work to the subject. This book provides a straightforward systematic approach to "right-sizing" animal-based experiments, with sample size estimates based on the fundamentals of statistical thinking: structured research questions, variation control and appropriate design of experiments. The result is a much-needed guide to planning animal-based experiments to ensure scientifically valid and reliable results. This book offers: Step-by-step guidance in diverse methods for approximating and refining sample size Detailed treatment of research topics specific to animal-based research, including pilot, feasibility and proof-of-concept studies Sample size approximation methods for different types of data binary, continuous, ordinal, time to event and different study types description, comparison, nested designs, reference interval construction and dose-response studies Numerous worked examples, using real data from published papers, together with SAS and R code A Guide to Sample Size for Animal-Based Studies is a must-have reference for preclinical and veterinary researchers, as well as ethical oversight committees and policymakers.

Download or read book Fishery Bulletin written by and published by . This book was released on 1983 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

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Download or read book Special Scientific Report written by and published by . This book was released on 1970 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Report on Investigations from 1964 to 1966 written by North Pacific Fur Seal Commission and published by . This book was released on 1969 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Supplementary report. Primarily a compilation of data in table form. Includes population dynamics, distribution and food habits. Focuses primarily on fur seals from Robben Island, Commander Islands and the Pribilof Islands.

Download or read book Gambling on Indian Reservations and Lands written by United States. Congress. Senate. Select Committee on Indian Affairs and published by . This book was released on 1985 with total page 720 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Administrative Report LJ written by and published by . This book was released on 1991 with total page 38 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Appendix to The Case of the United States Before the Tribunal of Arbitration to Convene at Paris Under the Provisions of the Treaty Between the United States of America and Great Britain Concluded February 29 1892 written by United States and published by . This book was released on 1892 with total page 688 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Report of the United States Commissioner of Fisheries for the Fiscal Year with Appendixes written by United States. Bureau of Fisheries and published by . This book was released on 1921 with total page 868 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Annual Report of the Commissioner of Fisheries written by United States. Bureau of Fisheries and published by . This book was released on 1922 with total page 962 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Report of the Commissioner for written by United States Fish Commission and published by . This book was released on 1917 with total page 770 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Alaska Fisheries and Fur Industries in written by and published by . This book was released on 1919 with total page 606 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Report on the Salmon Fisheries in Alaska written by and published by . This book was released on 1921 with total page 158 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Ocean Mammal Protection Hearings Before the Subcommittee on Oceans and Atmosphere 92 2 on S 685 1315 2579 2639 2871 3112 3161 and Amendment 1048 Ocean Mammal Legislation written by United States. Congress. Senate. Commerce and published by . This book was released on 1972 with total page 1232 pages. Available in PDF, EPUB and Kindle. Book excerpt:

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Download or read book Seal and Salmon Fisheries and General Resources of Alaska written by United States. Dept. of the Treasury. Special Agents Division and published by . This book was released on 1898 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Fur Seal Arbitration written by Bering Sea Tribunal of Arbitration and published by . This book was released on 1895 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: