Download or read book Prostaglandins Organ and Tissue specific Actions written by Stan Greenberg and published by Marcel Dekker. This book was released on 1982 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Prostaglandins Organ and Tissue Specific Actions written by Stan Greenberg and published by . This book was released on 1982-01-01 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Prostaglandins Organ and Tissue specific Actions written by Stan Greenberg and published by Marcel Dekker. This book was released on 1982 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Lipid Mediators written by Fiona M. Cunningham and published by . This book was released on 1994 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an overview of lipid mediators from synthesis to inhibition. It addresses the immune system and its diseases from a pharmacological viewpoint and combines clinical aspects with basic science.
Download or read book The Resolution of Inflammation written by Adriano Rossi and published by Springer Science & Business Media. This book was released on 2008-03-17 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area, including pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments.
Download or read book Prostacyclin and Its Stable Analogue Iloprost written by Ryszard Gryglewski and published by Springer. This book was released on 1987 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ten years after the discovery of prostacyclin, our knowledge of its biochemical mode of action, pharmacological properties, pathophysiological significance and therapeutic applications is ever expanding. Prostacyclin is both complex and unique as demonstrated by its unusual feature of being chemically and meta bolically unstable when compared to other prostanoids and known amine or peptide mediators. Although physiologically essential, the chemical instability of prostacyclin poses a serious drawback in laboratory and clinical studies. It is one of the genuine objectives of pharmaceutical research to supply synthetic compounds which overcome the inherent drawbacks - considering investigational and therapeutic use - of endogenous compounds. Whereas metabolic instability in certain cases could be of advantage, chemical instability definitely is not. With Iloprost, a molecule has been designed which - according to all data so far available - pertains high receptor affinity, metabolic instability (clinically this equates with a fine control of Iloprost's effects) while chemical stability has been achieved. By virtue of these characteristics Iloprost can be considered as one step towards specific interaction within the arachidonic acid cascade, namely the prostacyclin receptor. The aim of the symposium was to provide a critical experimental appraisal concerning the biochemical mode of action and pharmacological properties of prostacyclin and Iloprost.
Download or read book Blood Vessels and Lymphatics in Organ Systems written by David Abramson and published by Academic Press. This book was released on 2012-12-02 with total page 792 pages. Available in PDF, EPUB and Kindle. Book excerpt: Blood Vessels and Lymphatics on Organ Systems provides an introduction to the general and the specific characteristics of blood vessels and lymphatics in organ systems. It offers a structured, multidisciplinary approach to the broad field of vascular science, emphasizing both established and recent concepts. These include vascular networks such as those in the pineal, parathyroids, pancreas, adrenals, adipose tissue, and special senses; and functions of vascular endothelium. The book is organized into two parts. Part One on the general properties of blood vessels and lymphatics deals with the general aspects of the arteries, veins, microcirculation, and lymphatic channels. Part Two discusses the embryologic, morphologic, physiologic, pharmacologic, pathophysiologic, and pathologic characteristics of blood and lymph circulations in each of the important organ systems. This book was written for graduate students in the areas of blood and lymph circulation and for advanced research workers or clinicians seeking sources of information on advances in cardiovascular science.
Download or read book Holland Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2004 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Download or read book Part 1 MRCOG Revision Notes and Sample SBAs written by Neelanjana Mukhopadhaya and published by Cambridge University Press. This book was released on 2020-12-10 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise yet comprehensive guide is focused on the curriculum and current exam style of the MRCOG Part 1 examination. It integrates clinical knowledge with basic science, providing readers with a deeper understanding of pathophysiology of medical disorders in obstetrics and gynaecology. The lead editor is a member of the Part 1 Examination Committee and her insights are skilfully woven into the book's revision notes, sample Single Best Answer (SBA) question and answer explanations, and tips on exam technique. The book encourages a structured thought process to develop, making it easier for clinicians to make differential diagnoses and conduct relevant investigations and treatment plans. The focus on basic sciences also endows readers with the ability to develop research ideas and evaluate findings. Featuring easy-to-read text, highlighted key points, illustrations, and plenty of practice papers, this succinct guide is essential preparation reading for trainee obstetricians and gynaecologists taking the challenging Part 1 MRCOG exam.
Download or read book The Eicosanoids written by Peter Curtis-Prior and published by John Wiley & Sons. This book was released on 2004-07-16 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive reference work, updated from the first edition, brings together the knowledge and expertise of contributors from around the world. It includes new topics such as prostaglandin synthetase enzyme, new synthetic eicosanoids, innovative analytical methods, the influence of cytokines in the regulation of synthesis and actions, newer eicosanoids that influence the cardiovascular system, and newly discovered roles in reproduction and interactions with nitric oxide. This book satisfies a surge of interest in prostaglandins—NSAIDS (e.g. aspirin) are the biggest selling drugs of all time, and the field has been refreshed by the advent of new types (selective COX-2 inhibitors, anti-leukotiene drugs).
Download or read book Principles of Bone Biology written by John P. Bilezikian and published by Academic Press. This book was released on 2008-09-29 with total page 2074 pages. Available in PDF, EPUB and Kindle. Book excerpt: Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field The essential resource for anyone involved in the study of bones and bone diseases Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics Readers can easily search and locate information quickly as it will be online with this new edition
Download or read book Microcirculation written by Ronald F. Tuma and published by Academic Press. This book was released on 2011-04-28 with total page 999 pages. Available in PDF, EPUB and Kindle. Book excerpt: This reference is a volume in the Handbook of Physiology, co-published with The American Physiological Society. Growth in knowledge about the microcirculation has been explosive with the field becoming fragmented into numerous subdisciplines and subspecialties. This volume pulls all of the critical information into one volume. Meticulously edited and reviewed. Benefit: Provides investigators a unique tool to explore the significance of their findings in the context of other aspects of the microcirculation. In this way, the updated edition has a direct role in helping to develop new pathways of research and scholarship Highlights the explosive growth in knowledge about the microcirculation including the biology of nitric oxide synthase (NOS), endothelial cell signaling, angiogenesis, cell adhesion molecules, lymphocyte trafficking, ion channels and receptors, and propagated vasomotor responses. Benefit: Microcirculatory biology has become fragmented into numerous sub-disciplines and subspecialties, and these reference reintegrates the information in one volume
Download or read book The Physiology and Pharmacology of the Microcirculation written by Nicholas Mortillaro and published by Elsevier. This book was released on 2012-12-02 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Physiology and Pharmacology of the Microcirculation, Volume 1 discusses the biochemistry, metabolism, pharmacology, and physiology of the general microcirculation. This volume is organized into nine chapters that explore the microcirculation in several organ systems, such as brain, eye, heart, and kidney. The introductory chapters treat the biochemistry of isolated elements of the microvasculature, with special emphasis on the central nervous system. These chapters also explore the microvascular element and the vascular smooth muscle, focusing on their ultrastructural characteristics, innervation, and contraction-relaxation, and the effects of both endogenous and pharmacological vasoactive substances on vascular smooth muscle. The subsequent chapters deal with the exchange mode of the microcirculation; the mechanisms involved in the regulation of transcapillary fluid exchange; and the permeability of capillaries to small and large molecules in a variety of tissues. A discussion on the control mechanisms modulating microcirculatory dynamics is also included. The remaining four chapters are organized to deal with the microcirculation process in selected organs.
Download or read book Fluorine and Health written by Alain Tressaud and published by Elsevier. This book was released on 2008-06-06 with total page 821 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluorine and Health presents a critical multidisciplinary overview on the contribution of fluorinated compounds to resolve the important global issue of medicinal monitoring and health care. The involved subjects are organized in three thematic parts devoted to Molecular Imaging, Biomedical Materials and Pharmaceuticals. Initially the key-position of partially fluorinated low molecular weight compounds labelled either with the natural 19F-isotope for Magnetic Resonance Imaging (MRI) or labelled with the radioactive [18F]-isotope for Positron Emission Tomography (PET) is highlighted. Both non-invasive methods belong to the most challenging in vivo imaging techniques in oncology, neurology and in cardiology for the diagnosis of diseases having the highest mortality in the industrialized countries. The manifold facets of fluorinated biomaterials range from inorganic ceramics to perfluorinated organic molecules. Liquid perfluorocarbons are suitable for oxygen transport and as potential respiratory gas carriers, while fluorinated polymers are connected to the pathology of blood vessels. Another important issue concerns the application of highly fluorinated liquids in ophthalmology. Moreover, fluorine is an essential trace element in bone mineral, dentine and tooth enamel and is applied for the prophylaxis and treatment of dental caries. The various origins of human exposure to fluoride species is detailed to promote a better understanding of the effect of fluoride species on living organisms.Medicinally relevant fluorinated molecules and their interactions with native proteins are the main focus of the third part. New molecules fluorinated in strategic position are crucial for the development of pharmaceuticals with desired action and optimal pharmacological profile. Among the hundreds of marketed active drug components there are more than 150 fluorinated compounds. The chapters will illustrate how the presence of fluorine atoms alters properties of bioactive compounds at various biochemical steps, and possibly facilitate its emergence as pharmaceuticals. Finally the synthetic potential of a fluorinase, the first C-F bond forming enzyme, is summarized. New approach of topics involving chemistry, biology and medicinal techniques Transdisciplinar papers on fluoride products Importance of fluoride products in health Updated data on specific topics
Download or read book Immunobiology of the Macrophage written by David S. Nelson and published by Academic Press. This book was released on 2014-06-28 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunobiology of the Macrophage presents an account of the state of knowledge of the immunobiology of the macrophage. The book’s contributors—immunologists of diverse scientific and geographic backgrounds—have been encouraged to give personal accounts of developments in their special fields of interest as well as critical surveys of the backgrounds leading to these developments. The book begins with a study on the functions of macrophages in the initiation and regulation of antibody responses in vitro. This is followed by separate chapters on topics such as the role of macrophages in making antigen more immunogenic and less tolerogenic; functional distinctions between macrophages at different sites; and the role of the macrophage in antigen recognition by T lymphocytes. Subsequent chapters examine interactions between macrophages and lymphocytes in the production of interferon and other mediators of cellular immunity; macrophage cell lines and their uses in immunobiology; and cytotoxic macrophages in allograft rejection.
Download or read book Preterm Birth written by Institute of Medicine and published by National Academies Press. This book was released on 2007-05-23 with total page 791 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increasing prevalence of preterm birth in the United States is a complex public health problem that requires multifaceted solutions. Preterm birth is a cluster of problems with a set of overlapping factors of influence. Its causes may include individual-level behavioral and psychosocial factors, sociodemographic and neighborhood characteristics, environmental exposure, medical conditions, infertility treatments, and biological factors. Many of these factors co-occur, particularly in those who are socioeconomically disadvantaged or who are members of racial and ethnic minority groups. While advances in perinatal and neonatal care have improved survival for preterm infants, those infants who do survive have a greater risk than infants born at term for developmental disabilities, health problems, and poor growth. The birth of a preterm infant can also bring considerable emotional and economic costs to families and have implications for public-sector services, such as health insurance, educational, and other social support systems. Preterm Birth assesses the problem with respect to both its causes and outcomes. This book addresses the need for research involving clinical, basic, behavioral, and social science disciplines. By defining and addressing the health and economic consequences of premature birth, this book will be of particular interest to health care professionals, public health officials, policy makers, professional associations and clinical, basic, behavioral, and social science researchers.
Download or read book Endometriosis written by Tasuku Harada and published by Springer. This book was released on 2014-08-06 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: Endometriosis is one of the most common gynecological diseases, causing pelvic pain, infertility, and cancer. The condition reduces the quality of life for the estimated 10% of menstruating women who are affected by it. This book provides a clear insight into the pathogenesis and pathophysiology of endometriosis—essential information for clinicians intending to successfully treat the condition. The first part covers a range of topics including stem cells, NK cells, macrophages, inflammation, cytokines, epigenetics, prostaglandin, sex steroids, aromatase, apoptosis, nerve fibers, and malignant transformation to aid in understanding the pathogenesis and pathophysiology of the disease. The second part provides useful tools for therapy, specifically, notable recent techniques in prevention, imaging, biomarkers, medical treatments, surgical treatments, prevention of recurrence, and infertility treatments. Each chapter was written by an expert in the field, with nearly 40 researchers and clinicians contributing to the work. This book will be highly useful to clinicians as well as to research scientists who are interested in this enigmatic disease.
