Download or read book Product Safety Evaluation Handbook Second Edition written by Shayne C. Gad and published by CRC Press. This book was released on 1999-07-02 with total page 712 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Provides comprehensive, single-source coverage of the latest toxicity testing requirements and methods for personal care products, industrial and agricultural chemicals, and consumer goods. Second Edition, contains a new chapter on toxicokinetic testing and modeling, offers the latest solutions to common problems in testing and risk assessment, supplies an updated bibliography and more than 1300 references-over 100 new to this edition, and more."

Download or read book Product Safety Evaluation Handbook Second Edition written by Shayne C. Gad and published by CRC Press. This book was released on 1999-07-02 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Provides comprehensive, single-source coverage of the latest toxicity testing requirements and methods for personal care products, industrial and agricultural chemicals, and consumer goods. Second Edition, contains a new chapter on toxicokinetic testing and modeling, offers the latest solutions to common problems in testing and risk assessment, supplies an updated bibliography and more than 1300 references-over 100 new to this edition, and more."

Download or read book Product Safety Evaluation Handbook written by Shayne C. Gad and published by . This book was released on 1988 with total page 664 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Impact Evaluation in Practice Second Edition written by Paul J. Gertler and published by World Bank Publications. This book was released on 2016-09-12 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of the Impact Evaluation in Practice handbook is a comprehensive and accessible introduction to impact evaluation for policy makers and development practitioners. First published in 2011, it has been used widely across the development and academic communities. The book incorporates real-world examples to present practical guidelines for designing and implementing impact evaluations. Readers will gain an understanding of impact evaluations and the best ways to use them to design evidence-based policies and programs. The updated version covers the newest techniques for evaluating programs and includes state-of-the-art implementation advice, as well as an expanded set of examples and case studies that draw on recent development challenges. It also includes new material on research ethics and partnerships to conduct impact evaluation. The handbook is divided into four sections: Part One discusses what to evaluate and why; Part Two presents the main impact evaluation methods; Part Three addresses how to manage impact evaluations; Part Four reviews impact evaluation sampling and data collection. Case studies illustrate different applications of impact evaluations. The book links to complementary instructional material available online, including an applied case as well as questions and answers. The updated second edition will be a valuable resource for the international development community, universities, and policy makers looking to build better evidence around what works in development.

Download or read book Leachables and Extractables Handbook written by Douglas J. Ball and published by John Wiley & Sons. This book was released on 2012-01-24 with total page 702 pages. Available in PDF, EPUB and Kindle. Book excerpt: A practical and science-based approach for addressing toxicological concerns related to leachables and extractables associated with inhalation drug products Packaging and device components of Orally Inhaled and Nasal Drug Products (OINDP) such as metered dose inhalers, dry powder inhalers, and nasal sprays pose potential safety risks from leachables and extractables, chemicals that can be released or migrate from these components into the drug product. Addressing the concepts, background, historical use, and development of safety thresholds and their utility for qualifying leachables and extractables in OINDP, the Leachables and Extractables Handbook takes a practical approach to familiarize readers with the recent recommendations for safety and risk assessment established through a joint effort of scientists from the FDA, academia, and industry. Coverage includes best practices for the chemical evaluation and management of leachables and extractables throughout the pharmaceutical product life cycle, as well as: Guidance for pharmaceutical professionals to qualify and risk-assess container closure system leachables and extractables in drug products Principles for defining toxicological safety thresholds that are applicable to OINDP and potentially applicable to other drug products Regulatory perspectives, along with an appendix of key terms and definitions, case studies, and sample protocols Analytical chemists, packaging and device engineers, formulation development scientists, component suppliers, regulatory affairs specialists, and toxicologists will all benefit from the wealth of information offered in this important text.

Download or read book Health Information Technology Evaluation Handbook written by Vitaly Herasevich, MD, PhD, MSc and published by CRC Press. This book was released on 2017-10-24 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Governments and clinical providers are investing billions of dollars in health information technologies. This is being done with the expectation that HIT adoption will translate into healthier patients experiencing better care at lower cost. As the first wave of adoption comes to an end, stakeholders are ready to evaluate the results of their investment and make decisions about future directions. As a result, structured evaluations of a projects impact are an essential element of the justification for investment in HIT. This book provides an easy-to-read reference outlining the basic concepts, theory, and methods required to perform a systematic evaluation of HIT.

Download or read book Drug Safety Evaluation written by Shayne Cox Gad and published by John Wiley & Sons. This book was released on 2016-11-18 with total page 918 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical guide presents a road map for safety assessment as an integral part of the development of new drugs and therapeutics. Helps readers solve scientific, technical, and regulatory issues in preclinical safety assessment and early clinical drug development Explains scientific and philosophical bases for evaluation of specific concerns – including local tissue tolerance, target organ toxicity and carcinogenicity, developmental toxicity, immunogenicity, and immunotoxicity Covers the development of new small and large molecules, generics, 505(b)(2) route NDAs, and biosimilars Revises material to reflect new drug products (small synthetic, large proteins and cells, and tissues), harmonized global and national regulations, and new technologies for safety evaluation Adds almost 20% new and thoroughly updates existing content from the last edition

Download or read book Regulatory Toxicology Second Edition written by Shayne C. Gad and published by CRC Press. This book was released on 2001-07-19 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical resource provides toxicologists and scientists with essential information on the regulations that govern their jobs and products. Regulatory Toxicology also covers the scientific and historical underpinnings of those regulations. Each chapter provides a grounding in the historical events that led to the development of original legislation and major subsequent changes in legislation. The major administrative divisions for regulatory agencies and their main missions and responsibilities are also detailed, as are the basic filing units or documents the agencies require of individuals to meet goals. This second edition is updated to reflect new developments in the field.

Download or read book Safety Evaluation of Medical Devices written by Shayne C. Gad and published by CRC Press. This book was released on 2001-12-04 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Capturing the growth of the global medical device market in recent years, this practical new guide is essential for all who are responsible for ensuring safety in the use and manufacture of medical devices. It has been extensively updated to reflect significant advances, incorporating combination products and helpful case examples of current real-life problems in the field. The Third Edition explores these key current trends: global device markets continually advancing technology the increasing harmonization of device safety regulation worldwide Each aspect of safety evaluation is considered in terms of International Standards Organization (ISO), US Food and Drug Administration (FDA), European Union (EU), and Japanese Ministry of Health and Welfare (MHW) perspectives. In addition, the book reflects the role of the continuing growth of technology in the incorporation of science, particularly in the areas of immunotoxicology and toxicokinetics.

Download or read book Violence Assessment and Intervention written by Florian and published by CRC Press. This book was released on 2008-12-22 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt: Behavioral science has revealed a wealth of information concerning violence assessment in a wide variety of situations, but the challenge confronted by those dealing with potentially hostile populations is the effective application of this knowledge. Now in its second edition, Violence Assessment and Intervention: The Practitioner‘s Handbook, Secon

Download or read book Product Reliability Maintainability and Supportability Handbook written by Michael Pecht and published by CRC Press. This book was released on 2009-04-16 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: To ensure product reliability, an organization must follow specific practices during the product development process that impact reliability. The second edition of the bestselling Product Reliability, Maintainability, and Supportability Handbook helps professionals identify the shortcomings in the reliability practices of their organizations and em

Download or read book International Handbook of Threat Assessment written by J. Reid Meloy and published by Oxford University Press. This book was released on 2021 with total page 761 pages. Available in PDF, EPUB and Kindle. Book excerpt: Revised edition of International handbook of threat assessment, [2014]

Download or read book In Vitro Toxicology Second Edition written by Shayne C. Gad and published by CRC Press. This book was released on 2000-11-02 with total page 419 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicology has made tremendous strides in the sophistication of the models used to identify and understand the mechanisms of agents that can harm or kill humand and other higher organisms. Non-animals or in vitro models started to gain significant use in the 1960s. As a result of the increased concern over animal welfare, economic factors, and the need for greater sensitivity and understanding of mechanisms, interest in in vitro^n models has risen. This volume demonstrates that there now exists a broad range of in vitro models for use in either identifying or understanding most forms of toxicity. The availability of in vitro models spans both the full range of endpoints (irritation, sensitization, lethality, mutagenicity, and devlopmental toxicity) and the full spectrum of target organ systems (skin, eye, heart, liver, kidney, nervous system, etc.). Chapters are devoted to each of these speciality areas from a perspective of presenting the principal models and their uses and limitations. Chapters that overview the principles involved in the general selection and use of models, and that address the issues of safety concerns and regulatory acceptance of these methods are also included.

Download or read book Handbook on Impact Evaluation written by Shahidur R. Khandker and published by World Bank Publications. This book was released on 2009-10-13 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Public programs are designed to reach certain goals and beneficiaries. Methods to understand whether such programs actually work, as well as the level and nature of impacts on intended beneficiaries, are main themes of this book.

Download or read book Handbook of Practical Program Evaluation written by Joseph S. Wholey and published by Jossey-Bass. This book was released on 2004-06-08 with total page 600 pages. Available in PDF, EPUB and Kindle. Book excerpt: The second edition of Handbook of Practical Program Evaluation offers managers, analysts, consultants, and educators in government, nonprofit, and private institutions a valuable resource that outlines efficient and economical methods for assessing program results and identifying ways to improve program performance. The Handbook has been thoroughly revised. Many new chapters have been prepared for this edition, including chapters on logic modeling and on evaluation applications for small nonprofit organizations. The Handbook of Practical Program Evaluation is a comprehensive resource on evaluation, covering both in-depth program evaluations and performance monitoring. It presents evaluation methods that will be useful at all levels of government and in nonprofit organizations.

Download or read book American Herbal Products Association s Botanical Safety Handbook Second Edition written by Zoë Gardner and published by CRC Press. This book was released on 2013-03-15 with total page 1073 pages. Available in PDF, EPUB and Kindle. Book excerpt: Access to accurate, evidence-based, and clinically relevant information is essential to anyone who uses or recommends herbal products. With input from some of the most respected experts in herbal and integrative medicine, this completely revised edition of the American Herbal Products Association’s Botanical Safety Handbook reviews both traditional knowledge and contemporary research on herbs to provide an authoritative resource on botanical safety. The book covers more than 500 species of herbs and provides a holistic understanding of safety through data compiled from clinical trials, pharmacological and toxicological studies, medical case reports, and historical texts. For each species, a brief safety summary is provided for quick reference, along with a detailed review of the literature. Easily understood classification systems are used to indicate the safety of each listed species and the potential for the species to interact with drugs. Enhancements to the Second Edition include: Classification of each herb with both a safety rating and a drug interaction rating More references listed for each individual herb, vetted for accuracy Specific information on adverse events reported in clinical trials or case reports Safety-related pharmacology and pharmacokinetics of each herb, including drug interactions Additional information on the use of herbs by pregnant or lactating women Toxicological studies and data on toxic compounds Representing the core of the botanical trade and comprising the finest growers, processors, manufacturers, and marketers of herbal products, the mission of the AHPA is to promote the responsible commerce of herbal products. The American Herbal Products Association Botanical Safety Handbook, Second Edition ensures that this vision is attained. The book will be a valuable reference for product manufacturers, healthcare practitioners, regulatory agencies, researchers, and consumers of herbal products.

Download or read book written by Jean-Christophe Rufin and published by W. W. Norton & Company. This book was released on 2002-08-01 with total page 1092 pages. Available in PDF, EPUB and Kindle. Book excerpt: The sequel to The Abyssinian finds Jean-Baptiste Poncet in Persia practicing medicine for the Shah and trying to rescue his wife and daughter from inside the walls of a city under attack. Reprint. 11,500 first printing.