Download or read book Principles of Experimental Design for the Life Sciences written by Murray R. Selwyn and published by CRC Press. This book was released on 1996-05-23 with total page 176 pages. Available in PDF, EPUB and Kindle. Book excerpt: Let this down-to-earth book be your guide to the statistical integrity of your work. Without relying on the detailed and complex mathematical explanations found in many other statistical texts, Principles of Experimental Design for the Life Sciences teaches how to design, conduct, and interpret top-notch life science studies. Learn about the planning of biomedical studies, the principles of statistical design, sample size estimation, common designs in biological experiments, sequential clinical trials, high dimensional designs and process optimization, and the correspondence between objectives, design, and analysis. Each of these important topics is presented in an understandable and non-technical manner, free of statistical jargon and formulas. Written by a biostatistical consultant with 25 years of experience, Principles of Experimental Design for the Life Sciences is filled with real-life examples from the author's work that you can quickly and easily apply to your own. These examples illustrate the main concepts of experimental design and cover a broad range of application areas in both clinical and nonclinical research. With this one innovative, helpful book you can improve your understanding of statistics, enhance your confidence in your results, and, at long last, shake off those statistical shackles!
Download or read book Experimental Design for the Life Sciences written by Graeme D. Ruxton and published by Oxford University Press, USA. This book was released on 2006 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experimental Design for the Life Sciences teaches the reader how to effectively design experiments, to ensure that today's students are equipped with the skills they need to be the researchers of tomorrow. With a refreshingly approachable and articulate style, the book explains the essential elements of experimental design in clear, practical terms, so that the reader can grasp and apply even the most challenging concepts, including power analysis and pseudoreplication.
Download or read book Experimental Design in Biotechnology written by Perry D. Haaland and published by CRC Press. This book was released on 2020-11-25 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides the first time user of statistics with an understanding of how and why statistical experimental design and analysis can be an effective problem solving tool. It presents experimental designs which are useful for small screening and response surface experiments.
Download or read book Statistical Design and Analysis of Biological Experiments written by Hans-Michael Kaltenbach and published by Springer Nature. This book was released on 2021-04-15 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: This richly illustrated book provides an overview of the design and analysis of experiments with a focus on non-clinical experiments in the life sciences, including animal research. It covers the most common aspects of experimental design such as handling multiple treatment factors and improving precision. In addition, it addresses experiments with large numbers of treatment factors and response surface methods for optimizing experimental conditions or biotechnological yields. The book emphasizes the estimation of effect sizes and the principled use of statistical arguments in the broader scientific context. It gradually transitions from classical analysis of variance to modern linear mixed models, and provides detailed information on power analysis and sample size determination, including ‘portable power’ formulas for making quick approximate calculations. In turn, detailed discussions of several real-life examples illustrate the complexities and aberrations that can arise in practice. Chiefly intended for students, teachers and researchers in the fields of experimental biology and biomedicine, the book is largely self-contained and starts with the necessary background on basic statistical concepts. The underlying ideas and necessary mathematics are gradually introduced in increasingly complex variants of a single example. Hasse diagrams serve as a powerful method for visualizing and comparing experimental designs and deriving appropriate models for their analysis. Manual calculations are provided for early examples, allowing the reader to follow the analyses in detail. More complex calculations rely on the statistical software R, but are easily transferable to other software. Though there are few prerequisites for effectively using the book, previous exposure to basic statistical ideas and the software R would be advisable.
Download or read book Understanding Statistics and Experimental Design written by Michael H. Herzog and published by Springer. This book was released on 2019-08-13 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access textbook provides the background needed to correctly use, interpret and understand statistics and statistical data in diverse settings. Part I makes key concepts in statistics readily clear. Parts I and II give an overview of the most common tests (t-test, ANOVA, correlations) and work out their statistical principles. Part III provides insight into meta-statistics (statistics of statistics) and demonstrates why experiments often do not replicate. Finally, the textbook shows how complex statistics can be avoided by using clever experimental design. Both non-scientists and students in Biology, Biomedicine and Engineering will benefit from the book by learning the statistical basis of scientific claims and by discovering ways to evaluate the quality of scientific reports in academic journals and news outlets.
Download or read book Experimental Design for the Life Sciences written by Graeme Ruxton and published by Oxford University Press. This book was released on 2011 with total page 197 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing students with clear and practical advice on how best to organise experiments and collect data so as to make the subsequent analysis easier and their conclusions more robust, this text assumes no specialist knowledge.
Download or read book The Principles of Experimental Research written by K Srinagesh and published by Elsevier. This book was released on 2011-04-01 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: The need to understand how to design and set up an investigative experiment is nearly universal to all students in engineering, applied technology and science, as well as many of the social sciences. Many schools offer courses in this fundamental skill and this book is meant to offer an easily accessible introduction to the essential tools needed, including an understanding of logical processes, how to use measurement, the do’s and don’ts of designing experiments so as to achieve reproducible results and the basic mathematical underpinnings of how data should be analyzed and interpreted. The subject is also taught as part of courses on Engineering statistics, Quality Control in Manufacturing, and Senior Design Project, in which conducting experimental research is usually integral to the project in question. * Covers such essential fundamentals as "definitions," "quantification," and standardization of test materials * Shows students and professionals alike how to plan an experiment—from how to frame a proper Hypothesis to designing an experiment to accurately reflect the nature of the problem to "designing with factors." * Includes a separate section on the use of Statistics in Experimental Research, including overview of probability and statistics, as well as Randomization, Replication and Sampling, as well as proper ways to draw statistical inferences from experimental data.
Download or read book Design of Experiments for Agriculture and the Natural Sciences written by Reza Hoshmand and published by CRC Press. This book was released on 2018-10-03 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written to meet the needs of both students and applied researchers, Design of Experiments for Agriculture and the Natural Sciences, Second Edition serves as an introductory guide to experimental design and analysis. Like the popular original, this thorough text provides an understanding of the logical underpinnings of design and analysis by selecting and discussing only those carefully chosen designs that offer the greatest utility. However, it improves on the first edition by adhering to a step-by-step process that greatly improves accessibility and understanding. Real problems from different areas of agriculture and science are presented throughout to show how practical issues of design and analysis are best handled. Completely revised to greatly enhance readability, this new edition includes: A new chapter on covariance analysis to help readers reduce errors, while enhancing their ability to examine covariances among selected variables Expanded material on multiple regression and variance analysis Additional examples, problems, and case studies A step-by-step Minitab® guide to help with data analysis Intended for those in the agriculture, environmental, and natural science fields as well as statisticians, this text requires no previous exposure to analysis of variance, although some familiarity with basic statistical fundamentals is assumed. In keeping with the book's practical orientation, numerous workable problems are presented throughout to reinforce the reader's ability to creatively apply the principles and concepts in any given situation.
Download or read book The Design of Experiments in Neuroscience written by Mary E. Harrington and published by Cambridge University Press. This book was released on 2020-02-06 with total page 201 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using engaging prose, Mary E. Harrington introduces neuroscience students to the principles of scientific research including selecting a topic, designing an experiment, analyzing data, and presenting research. This new third edition updates and clarifies the book's wealth of examples while maintaining the clear and effective practical advice of the previous editions. New and expanded topics in this edition include techniques such as optogenetics and conditional transgenes as well as a discussion of rigor and reproducibility in neuroscience research. Extended coverage of descriptive and inferential statistics arms readers with the analytical tools needed to interpret data. Throughout, practical guidelines are provided on avoiding experimental design problems, presenting research including creating posters and giving talks, and using a '12-step guide' to reading scientific journal articles.
Download or read book Experimental Design for Laboratory Biologists written by Stanley E. Lazic and published by Cambridge University Press. This book was released on 2016-12-08 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: Specifically intended for lab-based biomedical researchers, this practical guide shows how to design experiments that are reproducible, with low bias, high precision, and widely applicable results. With specific examples from research using both cell cultures and model organisms, it explores key ideas in experimental design, assesses common designs, and shows how to plan a successful experiment. It demonstrates how to control biological and technical factors that can introduce bias or add noise, and covers rarely discussed topics such as graphical data exploration, choosing outcome variables, data quality control checks, and data pre-processing. It also shows how to use R for analysis, and is designed for those with no prior experience. An accompanying website (https://stanlazic.github.io/EDLB.html) includes all R code, data sets, and the labstats R package. This is an ideal guide for anyone conducting lab-based biological research, from students to principle investigators working in either academia or industry.
Download or read book Scientific Research in Education written by National Research Council and published by National Academies Press. This book was released on 2002-03-28 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt: Researchers, historians, and philosophers of science have debated the nature of scientific research in education for more than 100 years. Recent enthusiasm for "evidence-based" policy and practice in educationâ€"now codified in the federal law that authorizes the bulk of elementary and secondary education programsâ€"have brought a new sense of urgency to understanding the ways in which the basic tenets of science manifest in the study of teaching, learning, and schooling. Scientific Research in Education describes the similarities and differences between scientific inquiry in education and scientific inquiry in other fields and disciplines and provides a number of examples to illustrate these ideas. Its main argument is that all scientific endeavors share a common set of principles, and that each fieldâ€"including education researchâ€"develops a specialization that accounts for the particulars of what is being studied. The book also provides suggestions for how the federal government can best support high-quality scientific research in education.
Download or read book Experimental and Quasi Experimental Designs for Research written by Donald T. Campbell and published by Ravenio Books. This book was released on 2015-09-03 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: We shall examine the validity of 16 experimental designs against 12 common threats to valid inference. By experiment we refer to that portion of research in which variables are manipulated and their effects upon other variables observed. It is well to distinguish the particular role of this chapter. It is not a chapter on experimental design in the Fisher (1925, 1935) tradition, in which an experimenter having complete mastery can schedule treatments and measurements for optimal statistical efficiency, with complexity of design emerging only from that goal of efficiency. Insofar as the designs discussed in the present chapter become complex, it is because of the intransigency of the environment: because, that is, of the experimenter’s lack of complete control.
Download or read book Design of Experiments for Engineers and Scientists written by Jiju Antony and published by Elsevier. This book was released on 2023-06-02 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition of Design of Experiments for Engineers and Scientists adds to the tried and trusted tools that were successful in so many engineering organizations with new coverage of design of experiments (DoE) in the service sector. Case studies are updated throughout, and new ones are added on dentistry, higher education, and utilities. Although many books have been written on DoE for statisticians, this book overcomes the challenges a wider audience faces in using statistics by using easy-to-read graphical tools. Readers will find the concepts in this book both familiar and easy to understand, and users will soon be able to apply them in their work or research. This classic book is essential reading for engineers and scientists from all disciplines tackling all kinds of product and process quality problems and will be an ideal resource for students of this topic. Written in nonstatistical language, the book is an essential and accessible text for scientists and engineers who want to learn how to use DoE Explains why teaching DoE techniques in the improvement phase of Six Sigma is an important part of problem-solving methodology New edition includes two new chapters on DoE for services as well as case studies illustrating its wider application in the service industry
Download or read book Experimental Design written by S.N. Deming and published by Elsevier. This book was released on 1987-01-01 with total page 285 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now available in a paperback edition is a book which has been described as ``...an exceptionally lucid, easy-to-read presentation... would be an excellent addition to the collection of every analytical chemist. I recommend it with great enthusiasm.'' (Analytical Chemistry). Unlike most current textbooks, it approaches experimental design from the point of view of the experimenter, rather than that of the statistician. As the reviewer in `Analytical Chemistry' went on to say: ``Deming and Morgan should be given high praise for bringing the principles of experimental design to the level of the practicing analytical chemist.''. The book first introduces the reader to the fundamentals of experimental design. Systems theory, response surface concepts, and basic statistics serve as a basis for the further development of matrix least squares and hypothesis testing. The effects of different experimental designs and different models on the variance-covariance matrix and on the analysis of variance (ANOVA) are extensively discussed. Applications and advanced topics (such as confidence bands, rotatability, and confounding) complete the text. Numerous worked examples are presented. The clear and practical approach adopted by the authors makes the book applicable to a wide audience. It will appeal particularly to those with a practical need (scientists, engineers, managers, research workers) who have completed their formal education but who still need to know efficient ways of carrying out experiments. It will also be an ideal text for advanced undergraduate and graduate students following courses in chemometrics, data acquisition and treatment, and design of experiments.
Download or read book Statistical Principles for the Design of Experiments written by R. Mead and published by Cambridge University Press. This book was released on 2012-09-13 with total page 587 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is about the statistical principles behind the design of effective experiments and focuses on the practical needs of applied statisticians and experimenters engaged in design, implementation and analysis. Emphasising the logical principles of statistical design, rather than mathematical calculation, the authors demonstrate how all available information can be used to extract the clearest answers to many questions. The principles are illustrated with a wide range of examples drawn from real experiments in medicine, industry, agriculture and many experimental disciplines. Numerous exercises are given to help the reader practise techniques and to appreciate the difference that good design can make to an experimental research project. Based on Roger Mead's excellent Design of Experiments, this new edition is thoroughly revised and updated to include modern methods relevant to applications in industry, engineering and modern biology. It also contains seven new chapters on contemporary topics, including restricted randomisation and fractional replication.
Download or read book The Design of Experiments written by R. Mead and published by Cambridge University Press. This book was released on 1990-07-26 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: In all the experimental sciences, good design of experiments is crucial to the success of research. Well-planned experiments can provide a great deal of information efficiently and can be used to test several hypotheses simultaneously. This book is about the statistical principles of good experimental design and is intended for all applied statisticians and practising scientists engaged in the design, implementation and analysis of experiments. Professor Mead has written the book with the emphasis on the logical principles of statistical design and employs a minimum of mathematics. Throughout he assumes that the large-scale analysis of data will be performed by computers and he is thus able to devote more attention to discussions of how all of the available information can be used to extract the clearest answers to many questions. The principles are illustrated with a wide range of examples drawn from medicine, agriculture, industry and other disciplines. Numerous exercises are given to help the reader practise techniques and to appreciate the difference that good design of experiments can make to a scientific project.
Download or read book Experimental Design and Data Analysis for Biologists written by Gerald Peter Quinn and published by Cambridge University Press. This book was released on 2002-03-21 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Regression, analysis of variance, correlation, graphical.
