Download or read book Preserving the Promise written by Scott Dessain and published by Academic Press. This book was released on 2016-10-05 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preserving the Promise: Improving the Culture of Biotech Investment critically examines why most biotech startups fail, as they emerge from universities into an ecosystem that inhibits rather than encourages innovation. This "Valley of Death" squanders our public investments in medical research and with them, the promise of longer and healthier lives. The authors explicate the Translation Gap faced by early stage biotech companies, the result of problematic technology transfer and investment practices, and provide specific prescriptions for improving translation of important discoveries into safe and effective therapies. In Preserving the Promise, Dessain and Fishman build on their collective experience as company founders, healthcare investor (Fishman) and physician/scientist (Dessain). The book offers a forward-looking, critical analysis of "conventional wisdom" that encumbers commercialization practices. It exposes the self-defeating habits of drug development in the Valley of Death, that waste money and extinguish innovative technologies through distorted financial incentives. - Explains why translation of biotech discovery into medicine succeeds so infrequently that it's been dubbed the Valley of Death - Uncovers specific decision-making strategies that more effectively align incentives, improving clinical and financial outcomes for investors, inventor/entrepreneurs, and patients - Examines the critical, early stages of commercialization, where technology transfer offices and Angels act as gatekeepers to development, and where tension between short-term financial and long-term clinical aspirations sinks important technologies - Deconstructs the forces driving biotech, recasts them in a proven conceptual framework, and offers practical guidance for making the system better

Download or read book Protecting the Promise to Our Seniors written by United States. Congress. Senate. Special Committee on Aging and published by . This book was released on 2011 with total page 64 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Promise and Peril written by Christopher McKnight Nichols and published by Harvard University Press. This book was released on 2011-08-11 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: Spreading democracy abroad or protecting business at home: this book offers a new look at the history of the contest between isolationalism and internationalism that is as current as the wars in Iraq and Afghanistan and as old as America itself, with profiles of the people, policies, and events that shaped the debate.

Download or read book Preserving Food Without Freezing Or Canning written by The Gardeners and Farmers of Centre Terre Vivante and published by Chelsea Green Publishing. This book was released on 2007-04-04 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translation of: Conserves naturelles des quatre saisons.

Download or read book Rena s Promise written by Rena Kornreich Gelissen and published by Beacon Press. This book was released on 2015-03-17 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: An expanded edition of the powerful memoir about two sisters' determination to survive during the Holocaust featuring new and never before revealed information about the first transport of women to Auschwitz In March 1942, Rena Kornreich and 997 other young women were rounded up and forced onto the first Jewish transport of women to Auschwitz. Soon after, Rena was reunited with her sister Danka at the camp, beginning a story of love and courage that would last three years and forty-one days. From smuggling bread for their friends to narrowly escaping the ever-present threats that loomed at every turn, the compelling events in Rena’s Promise remind us that humanity and hope can survive inordinate brutality.

Download or read book Getting Things Right written by Conor McHugh and published by Oxford University Press. This book was released on 2022-10-28 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some of our attitudes are fitting, others unfitting. It seems fitting to admire Mandela, but not Idi Amin, and to believe that the Seine flows through Paris, but not that the Thames does. Fitting attitudes get things right. Conor McHugh and Jonathan Way argue that fittingness is the key to understanding the normative domain--the domain of reasons, obligations, and value. They develop and defend a novel 'fittingness first' approach, on which fittingness is a normatively basic property and all other normative properties depend on fittingness. They show how this approach illuminates central questions in ethics and epistemology.

Download or read book A Promise for Miriam written by Vannetta Chapman and published by Harvest House Publishers. This book was released on 2012-07-01 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Promise for Miriam, the first book in a brand-new romantic series from popular author Vannetta Chapman, introduces the Amish community of Pebble Creek and some of the kind, caring people there. As they face challenges to their community from the English world, they come together to reach out to their non-Amish neighbors while still preserving their cherished Plain ways. Amish schoolteacher Miriam King loves her students. At 26, most women her age are married with children of their own, but she hasn’t yet met anyone who can convince her to give up the Plain school that sits along the banks of Pebble Creek. Then newcomer Gabriel Miller steps into her life, bringing his daughter, an air of mystery, and challenges Miriam has never faced before. Will Gabe be able to let go of the past that haunts him? He thinks he just wants to be left alone, but the loving and warm community he and his daughter have moved to has other plans for him. After a near tragedy is averted, he hesitantly returns offers of help and friendship, and he discovers he can make a difference to the people of Pebble Creek—and maybe find love again.

Download or read book Oxford Studies in Metaethics Volume 17 written by Russ Shafer-Landau and published by Oxford University Press. This book was released on 2022-04-20 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxford Studies in Metaethics is the only publication devoted exclusively to original philosophical work in the foundations of ethics. It provides an annual selection of much of the best new scholarship being done in the field. Its broad purview includes work being done at the intersections of ethical theory with metaphysics, epistemology, philosophy of language, and philosophy of mind. The essays included in the series provide an excellent basis for understanding recent developments in the field; those who would like to acquaint themselves with the current state of play in metaethics would do well to start here.

Download or read book Restoring Women s History Through Historic Preservation written by Gail Lee Dubrow and published by JHU Press. This book was released on 2003-01-28 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This essay collection draws upon work presented at three national conferences on women and historic preservation held at Bryn Mawr College in 1994, Arizona State University in 1997, and at Mount Vernon College in 2000.

Download or read book The Oxford Handbook of Consequentialism written by Douglas W. Portmore and published by Oxford University Press. This book was released on 2020-09-17 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt: Consequentialism is a major moral theory in contemporary philosophy: it is the view that the only thing that matters when making moral decisions is the outcome of those decisions. Consequentialists hold that to morally assess an act, we must first evaluate and rank the various ways that things could turn out depending on whether it or some alternative act is performed. Whether we should perform that act thus depends on how its outcome ranks relative to those of its alternatives. Consequentialism rivals deontology, contractualism, and virtue ethics, but, more importantly, it has influenced contemporary moral philosophy such that the consequentialist/non-consequentialist distinction is one of the most central in normative ethics. After all, every plausible moral theory must concede that the goodness of an act's consequences is something that matters, even if it's not the only thing that matters. Thus, all plausible moral theories will accept that both 1) an act's producing good consequences constitutes a moral reason to perform it, and 2) the better its consequences, the more of a moral reason there is to perform it. In this way, much of consequentialist ethical theory is important for normative ethics in general. This Oxford Handbook contains thirty-two previously unpublished contributions by top moral philosophers examining the current state of play in consequentialism and pointing to new directions for future research. The volume is organized into four major sections: foundational issues; objections to consequentialism; its forms and limits; and consequentialism's implications for policy, practice, and social reform.

Download or read book Preserving South Street Seaport written by James Michael Lindgren and published by NYU Press. This book was released on 2014 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: Preserving South Street Seaportatells the fascinating story, from the 1960s to the present, of the South Street Seaport District of Lower Manhattan. Home to the original Fulton Fish Market and then the South Street Seaport Museum, it is one of the last neighborhoods of late 18th- and early 19th-century New York City not to be destroyed by urban development. In 1988, South Street Seaport became the city's #1 destination for visitors. Featuring over 40 archival and contemporary black-and-white photographs, this is the first history of a remarkable historic district and maritime museum.a aaLindgren skillfully tells the complex story of this unique cobblestoned neighborhood. aComprised of deteriorating, 4-5 story buildings in what was known as the Fulton Fish Market, the neighborhood was earmarked for the erection of the World Trade Center until New Jersey forced its placement one mile westward. After Penn StationOCOs demolition had angered many New York citizens, preservationists mobilized in 1966 to save this last piece of ManhattanOCOs old port and recreate its fabled 19th-century Street of Ships. The South Street Seaport and the World Trade Center became the yin and yang of Lower ManhattanOCOs rebirth. In an unprecedented move, City Hall designated the museum as developer of the twelve-block urban renewal district.aaaHowever, the Seaport Museum, whose membership became the largest of any history museum in the city, was never adequately funded, and it suffered with the real estate collapse of 1972. The city, bankers, and state bought the museumOCOs fifty buildings and leased them back at terms that crippled the museum financially. That led to the controversial construction of the Rouse Company's New Fulton Market (1983) and Pier 17 mall (1985). Lindgren chronicles these years of struggle, as the defenders of the people-oriented museum and historic district tried to save the original streets and buildings and the largest fleet of historic ships in the country from the schemes of developers, bankers, politicians, and even museum administrators.aaThough the Seaport MuseumOCOs finances were always tenuous, the neighborhood and the museum were improving until the tragedy of 9/11. But the prolonged recovery brought on dysfunctional museum managers and indifference, if not hostility, from City Hall. Superstorm Sandy then dealt a crushing blow. Today, the future of this pioneering museum, designated by Congress as AmericaOCOs National Maritime Museum, is in doubt, as its waterfront district is eyed by powerful commercial developers. aWhileaPreserving South Street Seaportareveals the pitfalls of privatizing urban renewal, developing museum-corporate partnerships, and introducing a professional regimen over a peopleOCOs movement, it also tells the story of how a seedy, decrepit piece of waterfront became a wonderful venue for all New Yorkers and visitors from around the world to enjoy. aThis book will appeal to a wide audience of readers in the history and practice of museums, historic preservation, urban history and urban development, and contemporary New York City.a a This book is supported by a grant from Furthermore: a program of the J.M. Kaplan Fund.a"

Download or read book Preserving Digital Materials written by Douglas Ross Harvey and published by Walter de Gruyter. This book was released on 2008-12-18 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a single-volume introduction to the principles, strategies and practices currently applied by librarians and record keepers to the preservation of digital information. Also included are case studies of practice from the library, record keeping, audiovisual archiving, data archiving and geospatial communities.

Download or read book The Promise of the Foreign written by Vicente L. Rafael and published by Duke University Press. This book was released on 2005-12-05 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: In The Promise of the Foreign, Vicente L. Rafael argues that translation was key to the emergence of Filipino nationalism in the nineteenth century. Acts of translation entailed technics from which issued the promise of nationhood. Such a promise consisted of revising the heterogeneous and violent origins of the nation by mediating one’s encounter with things foreign while preserving their strangeness. Rafael examines the workings of the foreign in the Filipinos’ fascination with Castilian, the language of the Spanish colonizers. In Castilian, Filipino nationalists saw the possibility of arriving at a lingua franca with which to overcome linguistic, regional, and class differences. Yet they were also keenly aware of the social limits and political hazards of this linguistic fantasy. Through close readings of nationalist newspapers and novels, the vernacular theater, and accounts of the 1896 anticolonial revolution, Rafael traces the deep ambivalence with which elite nationalists and lower-class Filipinos alike regarded Castilian. The widespread belief in the potency of Castilian meant that colonial subjects came in contact with a recurring foreignness within their own language and society. Rafael shows how they sought to tap into this uncanny power, seeing in it both the promise of nationhood and a menace to its realization. Tracing the genesis of this promise and the ramifications of its betrayal, Rafael sheds light on the paradox of nationhood arising from the possibilities and risks of translation. By repeatedly opening borders to the arrival of something other and new, translation compels the nation to host foreign presences to which it invariably finds itself held hostage. While this condition is perhaps common to other nations, Rafael shows how its unfolding in the Philippine colony would come to be claimed by Filipinos, as would the names of the dead and their ghostly emanations.

Download or read book Landscapes of Conflict written by William G. Robbins and published by University of Washington Press. This book was released on 2009-11-23 with total page 458 pages. Available in PDF, EPUB and Kindle. Book excerpt: Post-World War II Oregon was a place of optimism and growth, a spectacular natural region from ocean to high desert that seemingly provided opportunity in abundance. With the passing of time, however, Oregon’s citizens — rural and urban — would find themselves entangled in issues that they had little experience in resolving. The same trees that provided income to timber corporations, small mill owners, loggers, and many small towns in Oregon, also provided a dramatic landscape and a home to creatures at risk. The rivers whose harnessing created power for industries that helped sustain Oregon’s growth — and were dumping grounds for municipal and industrial wastes — also provided passageways to spawning grounds for fish, domestic water sources, and recreational space for everyday Oregonians. The story of Oregon’s accommodation to these divergent interests is a divisive story between those interested in economic growth and perceived stability and citizens concerned with exercising good stewardship towards the state’s natural resources and preserving the state’s livability. In his second volume of Oregon’s environmental history, William Robbins addresses efforts by individuals and groups within and outside the state to resolve these conflicts. Among the people who have had roles in this process, journalists and politicians Richard Neuberger and Tom McCall left substantial legacies and demonstrated the ambiguities inherent in the issues they confronted.

Download or read book The Concepts of Ethics written by NA NA and published by Springer. This book was released on 2015-12-25 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Clearinghouse Review written by and published by . This book was released on 2011-05 with total page 80 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book All the Promises of the Bible written by Herbert Lockyer and published by Zondervan. This book was released on 2017-06-06 with total page 356 pages. Available in PDF, EPUB and Kindle. Book excerpt: Promises You Can Stand On Through Thick and Thin The Bible is filled with hundreds of what the apostle Peter called "exceeding great and precious promises": definite, explicit declarations God has made that you can count on. In All the Promises of the Bible, Dr. Herbert Lockyer discusses the nature of God’s promises - their substance, simplicity, surety, source, security, scope. Lockyer’s in-depth look at the scope of God’s promises arranges them in categories that cover the full array of human concerns, from the spiritual to the material and the corporate to the personal. As you come to understand God’s promises and how they apply to every aspect of your life, you’ll gain a trust in God that will sustain you through the worst of times and be your source of rejoicing in the best. X