Download or read book Patient Specific Computational Modeling written by Begoña Calvo Lopez and published by Springer Science & Business Media. This book was released on 2012-05-20 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses patient-specific modeling. It integrates computational modeling, experimental procedures, imagine clinical segmentation and mesh generation with the finite element method (FEM) to solve problems in computational biomedicine and bioengineering. Specific areas of interest include cardiovascular problems, ocular and muscular systems and soft tissue modeling. Patient-specific modeling has been the subject of serious research over the last seven years and interest in the area is continually growing and this area is expected to further develop in the near future.
Download or read book Cardiovascular Biomechanics written by Peter R. Hoskins and published by Springer. This book was released on 2017-02-16 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a balanced presentation of the fundamental principles of cardiovascular biomechanics research, as well as its valuable clinical applications. Pursuing an integrated approach at the interface of the life sciences, physics and engineering, it also includes extensive images to explain the concepts discussed. With a focus on explaining the underlying principles, this book examines the physiology and mechanics of circulation, mechanobiology and the biomechanics of different components of the cardiovascular system, in-vivo techniques, in-vitro techniques, and the medical applications of this research. Written for undergraduate and postgraduate students and including sample problems at the end of each chapter, this interdisciplinary text provides an essential introduction to the topic. It is also an ideal reference text for researchers and clinical practitioners, and will benefit a wide range of students and researchers including engineers, physicists, biologists and clinicians who are interested in the area of cardiovascular biomechanics.
Download or read book Patient Specific Modeling of the Cardiovascular System written by Roy C.P. Kerckhoffs and published by Springer Science & Business Media. This book was released on 2010-09-03 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Peter Hunter Computational physiology for the cardiovascular system is entering a new and exciting phase of clinical application. Biophysically based models of the human heart and circulation, based on patient-specific anatomy but also informed by po- lation atlases and incorporating a great deal of mechanistic understanding at the cell, tissue, and organ levels, offer the prospect of evidence-based diagnosis and treatment of cardiovascular disease. The clinical value of patient-specific modeling is well illustrated in application areas where model-based interpretation of clinical images allows a more precise analysis of disease processes than can otherwise be achieved. For example, Chap. 6 in this volume, by Speelman et al. , deals with the very difficult problem of trying to predict whether and when an abdominal aortic aneurysm might burst. This requires automated segmentation of the vascular geometry from magnetic re- nance images and finite element analysis of wall stress using large deformation elasticity theory applied to the geometric model created from the segmentation. The time-varying normal and shear stress acting on the arterial wall is estimated from the arterial pressure and flow distributions. Thrombus formation is identified as a potentially important contributor to changed material properties of the arterial wall. Understanding how the wall adapts and remodels its material properties in the face of changes in both the stress loading and blood constituents associated with infl- matory processes (IL6, CRP, MMPs, etc.
Download or read book Cardiovascular Mechanics written by Michel R. Labrosse and published by CRC Press. This book was released on 2018-09-13 with total page 386 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this book is to illustrate in specific detail how cardiovascular mechanics stands as a common pillar supporting such different clinical successes as drugs for high blood pressure, prosthetic heart valves and coronary artery bypass grafting, among others. This information is conveyed through a comprehensive treatment of the overarching principles and theories that are behind mechanobiological processes, aortic and arterial mechanics, atherosclerosis, blood and microcirculation, hear valve mechanics, as well as medical devices and drugs. Examines all major theoretical and practical aspects of mechanical forces related to the cardiovascular system. Discusses a unique coverage of mechanical changes related to an aging cardiovascular system. Provides an overview of experimental methods in cardiovascular mechanics. Written by world-class researchers from Canada, the US and EU. Extensive references are provided at the end of each chapter to enhance further study. Michel R. Labrosse is the founder of the Cardiovascular Mechanics Laboratory at the University of Ottawa, where he is a full professor within the Department of Mechanical Engineering. He has been an active researcher in academia along with being heavily associated with the University of Ottawa Heart Institute. He has authored or co-authored over 90 refereed communications, and supervised or co-supervised over 40 graduate students and post-docs.
Download or read book The Digital Patient written by C. D. Combs and published by John Wiley & Sons. This book was released on 2015-12-11 with total page 331 pages. Available in PDF, EPUB and Kindle. Book excerpt: A modern guide to computational models and constructive simulation for personalized patient care using the Digital Patient The healthcare industry’s emphasis is shifting from merely reacting to disease to preventing disease and promoting wellness. Addressing one of the more hopeful Big Data undertakings, The Digital Patient: Advancing Healthcare, Research, and Education presents a timely resource on the construction and deployment of the Digital Patient and its effects on healthcare, research, and education. The Digital Patient will not be constructed based solely on new information from all the “omics” fields; it also includes systems analysis, Big Data, and the various efforts to model the human physiome and represent it virtually. The Digital Patient will be realized through the purposeful collaboration of patients as well as scientific, clinical, and policy researchers. The Digital Patient: Advancing Healthcare, Research, and Education addresses the international research efforts that are leading to the development of the Digital Patient, the wealth of ongoing research in systems biology and multiscale simulation, and the imminent applications within the domain of personalized healthcare. Chapter coverage includes: The visible human The physiological human The virtual human Research in systems biology Multi-scale modeling Personalized medicine Self-quantification Visualization Computational modeling Interdisciplinary collaboration The Digital Patient: Advancing Healthcare, Research, and Education is a useful reference for simulation professionals such as clinicians, medical directors, managers, simulation technologists, faculty members, and educators involved in research and development in the life sciences, physical sciences, and engineering. The book is also an ideal supplement for graduate-level courses related to human modeling, simulation, and visualization.
Download or read book Computational Cardiovascular Mechanics written by Julius M. Guccione and published by Springer Science & Business Media. This book was released on 2010-01-08 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Cardiovascular Mechanics provides a cohesive guide to creating mathematical models for the mechanics of diseased hearts to simulate the effects of current treatments for heart failure. Clearly organized in a two part structure, this volume discusses various areas of computational modeling of cardiovascular mechanics (finite element modeling of ventricular mechanics, fluid dynamics) in addition to a description an analysis of the current applications used (solid FE modeling, CFD). Edited by experts in the field, researchers involved with biomedical and mechanical engineering will find Computational Cardiovascular Mechanics a valuable reference.
Download or read book Patient Specific Modeling in Tomorrow s Medicine written by Amit Gefen and published by Springer Science & Business Media. This book was released on 2012-01-05 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews the frontier of research and clinical applications of Patient Specific Modeling, and provides a state-of-the-art update as well as perspectives on future directions in this exciting field. The book is useful for medical physicists, biomedical engineers and other engineers who are interested in the science and technology aspects of Patient Specific Modeling, as well as for radiologists and other medical specialists who wish to be updated about the state of implementation.
Download or read book Statistical Atlases and Computational Models of the Heart Multi Disease Multi View and Multi Center Right Ventricular Segmentation in Cardiac MRI Challenge written by Esther Puyol Antón and published by Springer Nature. This book was released on 2022-01-14 with total page 397 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the proceedings of the 12th International Workshop on Statistical Atlases and Computational Models of the Heart, STACOM 2021, as well as the M&Ms-2 Challenge: Multi-Disease, Multi-View and Multi-Center Right Ventricular Segmentation in Cardiac MRI Challenge. The 25 regular workshop papers included in this volume were carefully reviewed and selected after being revised. They deal with cardiac imaging and image processing, machine learning applied to cardiac imaging and image analysis, atlas construction, artificial intelligence, statistical modelling of cardiac function across different patient populations, cardiac computational physiology, model customization, atlas based functional analysis, ontological schemata for data and results, integrated functional and structural analyses, as well as the pre-clinical and clinical applicability of these methods. In addition, 15 papers from the M&MS-2 challenge are included in this volume. The Multi-Disease, Multi-View & Multi-Center Right Ventricular Segmentation in Cardiac MRI Challenge (M&Ms-2) is focusing on the development of generalizable deep learning models for the Right Ventricle that can maintain good segmentation accuracy on different centers, pathologies and cardiac MRI views. There was a total of 48 submissions to the workshop.
Download or read book Artificial Intelligence for Computational Modeling of the Heart written by Tommaso Mansi and published by Academic Press. This book was released on 2019-11-28 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Artificial Intelligence for Computational Modeling of the Heart presents recent research developments towards streamlined and automatic estimation of the digital twin of a patient's heart by combining computational modeling of heart physiology and artificial intelligence. The book first introduces the major aspects of multi-scale modeling of the heart, along with the compromises needed to achieve subject-specific simulations. Reader will then learn how AI technologies can unlock robust estimations of cardiac anatomy, obtain meta-models for real-time biophysical computations, and estimate model parameters from routine clinical data. Concepts are all illustrated through concrete clinical applications.
Download or read book Advances in Heart Valve Biomechanics written by Michael S. Sacks and published by Springer. This book was released on 2019-04-08 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book covers the latest research development in heart valve biomechanics and bioengineering, with an emphasis on novel experimentation, computational simulation, and applications in heart valve bioengineering. The most current research accomplishments are covered in detail, including novel concepts in valvular viscoelasticity, fibril/molecular mechanisms of tissue behavior, fibril kinematics-based constitutive models, mechano-interaction of valvular interstitial and endothelial cells, biomechanical behavior of acellular valves and tissue engineered valves, novel bioreactor designs, biomechanics of transcatheter valves, and 3D heart valve printing. This is an ideal book for biomedical engineers, biomechanics, surgeons, clinicians, business managers in the biomedical industry, graduate and undergraduate students studying biomedical engineering, and medical students.
Download or read book Computational Modeling in Biomedical Engineering and Medical Physics written by Alexandru Morega and published by Academic Press. This book was released on 2020-10-02 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mathematical and numerical modelling of engineering problems in medicine is aimed at unveiling and understanding multidisciplinary interactions and processes and providing insights useful to clinical care and technology advances for better medical equipment and systems. When modelling medical problems, the engineer is confronted with multidisciplinary problems of electromagnetism, heat and mass transfer, and structural mechanics with, possibly, different time and space scales, which may raise concerns in formulating consistent, solvable mathematical models. Computational Medical Engineering presents a number of engineering for medicine problems that may be encountered in medical physics, procedures, diagnosis and monitoring techniques, including electrical activity of the heart, hemodynamic activity monitoring, magnetic drug targeting, bioheat models and thermography, RF and microwave hyperthermia, ablation, EMF dosimetry, and bioimpedance methods. The authors discuss the core approach methodology to pose and solve different problems of medical engineering, including essentials of mathematical modelling (e.g., criteria for well-posed problems); physics scaling (homogenization techniques); Constructal Law criteria in morphing shape and structure of systems with internal flows; computational domain construction (CAD and, or reconstruction techniques based on medical images); numerical modelling issues, and validation techniques used to ascertain numerical simulation results. In addition, new ideas and venues to investigate and understand finer scale models and merge them into continuous media medical physics are provided as case studies. Presents the fundamentals of mathematical and numerical modeling of engineering problems in medicine Discusses many of the most common modelling scenarios for Biomedical Engineering, including, electrical activity of the heart hemodynamic activity monitoring, magnetic drug targeting, bioheat models and thermography, RF and microwave hyperthermia, ablation, EMF dosimetry, and bioimpedance methods Includes discussion of the core approach methodology to pose and solve different problems of medical engineering, including essentials of mathematical modelling, physics scaling, Constructal Law criteria in morphing shape and structure of systems with internal flows, computational domain construction, numerical modelling issues, and validation techniques used to ascertain numerical simulation results
Download or read book Functional Imaging and Modeling of the Heart written by Daniel B. Ennis and published by Springer. This book was released on 2021-06-18 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 11th International Conference on Functional Imaging and Modeling of the Heart, which took place online during June 21-24, 2021, organized by the University of Stanford. The 65 revised full papers were carefully reviewed and selected from 68 submissions. They were organized in topical sections as follows: advanced cardiac and cardiovascular image processing; cardiac microstructure: measures and models; novel approaches to measuring heart deformation; cardiac mechanics: measures and models; translational cardiac mechanics; modeling electrophysiology, ECG, and arrhythmia; cardiovascular flow: measures and models; and atrial microstructure, modeling, and thrombosis prediction.
Download or read book Cardiovascular Solid Mechanics written by Jay D. Humphrey and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 766 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text presents a general introduction to soft tissue biomechanics. One of its primary goals is to introduce basic analytical, experimental and computational methods. In doing so, it enables readers to gain a relatively complete understanding of the biomechanics of the heart and vasculature.
Download or read book Patient specific Hemodynamic Computations Application to Personalized Diagnosis of Cardiovascular Pathologies written by Lucian Mihai Itu and published by Springer. This book was released on 2017-05-31 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hemodynamic computations represent a state-of-the-art approach for patient-specific assessment of cardiovascular pathologies. The book presents the development of reduced-order multiscale hemodynamic models for coronary artery disease, aortic coarctation and whole body circulation, which can be applied in routine clinical settings for personalized diagnosis. Specific parameter estimation frameworks are introduced for calibrating the parameters of the models and high performance computing solutions are employed to reduce their execution time. The personalized computational models are validated against patient-specific measurements. The book is written for scientists in the field of biomedical engineering focusing on the cardiovascular system, as well as for research-oriented physicians in cardiology and industrial players in the field of healthcare technologies.
Download or read book Biomechanics written by Donald R. Peterson and published by CRC Press. This book was released on 2014-12-13 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents Current Principles and ApplicationsBiomedical engineering is considered to be the most expansive of all the engineering sciences. Its function involves the direct combination of core engineering sciences as well as knowledge of nonengineering disciplines such as biology and medicine. Drawing on material from the biomechanics section of The
Download or read book 3 Dimensional Modeling in Cardiovascular Disease written by Evan M. Zahn and published by Elsevier Health Sciences. This book was released on 2019-09-14 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by physicians and surgeons, imaging specialists, and medical technology engineers, and edited by Dr. Evan M. Zahn of the renowned Cedars-Sinai Heart Institute, this concise, focused volume covers must-know information in this new and exciting field. Covering everything from the evolution of 3D modeling in cardiac disease to the various roles of 3D modeling in cardiology to cardiac holography and 3D bioprinting, 3-Dimensional Modeling in Cardiovascular Disease is a one-stop resource for physicians, cardiologists, radiologists, and engineers who work with patients, support care providers, and perform research. - Provides history and context for the use of 3D printing in cardiology settings, discusses how to use it to plan and evaluate treatment, explains how it can be used as an education resource, and explores its effectiveness with medical interventions. - Presents specific uses for 3D modeling of the heart, examines whether it improves outcomes, and explores 3D bioprinting. - Consolidates today's available information and guidance into a single, convenient resource.
Download or read book Mathematical Modeling of Cardiovascular Systems From Physiology to the Clinic written by Julius Guccione and published by Frontiers Media SA. This book was released on 2020-01-13 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt:
