Download or read book Practical manual on tuberculosis laboratory strengthening written by World Health Organization and published by World Health Organization. This book was released on 2022-10-31 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book WHO operational handbook on tuberculosis Module 3 written by World Health Organization and published by World Health Organization. This book was released on 2024-03-15 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: The “WHO operational handbook on tuberculosis. Module 3: Diagnosis - Rapid diagnostics for tuberculosis detection, third edition” is the latest edition replacing the one issued in 2021. A new class of technologies for drug susceptibility testing is endorsed by WHO and included in this edition: targeted next generation sequencing. The operational handbook aims at facilitating the implementation of the WHO recommendations by the Member States, technical partners, and others involved in managing patients with TB and DR-TB. It provides practical information on existing and new tests recommended by WHO, step-by-step advice on implementing and scale-up testing to achieve local and national impact and lastly, model diagnostic algorithms, which are updated to incorporate the latest recommendations. An overview of budgetary considerations and information sheets on each of the newly recommended tests is provided. The class of targeted next generation sequencing is recommended for the detection of resistance to a number of first- and second-line anti-TB drugs, rather than culture-based phenotypic drug susceptibility testing. The recommendations will open for faster detection of resistance to a range of anti-TB drugs directly from sputum samples.
Download or read book Practical manual of processing stool samples for diagnosis of childhood TB written by and published by World Health Organization. This book was released on 2022-04-28 with total page 44 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical manual aims to help countries implement stool testing into their TB diagnostic and clinical practice. It provides available evidence and incorporates recommendations on the use of stool as a sample type to diagnose TB. The target audience is staff at national TB programmes and TB laboratories and other health authorities and partners.
Download or read book Guidance for the surveillance of drug resistance in tuberculosis sixth edition written by and published by World Health Organization. This book was released on 2021-02-12 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this document is to assist national TB programmes in developing the strongest possible mechanisms of surveillance, starting from periodic country-specific surveys of sampled patients. The ultimate goal is to establish continuous surveillance systems based on routine drug susceptibility testing (DST). This guidance promotes certain standardized criteria for surveillance to ensure that results are comparable within and between countries over time. The target audience of this document is national TB programmes and, in particular, the coordination team for surveillance ideally composed of the programme manager, a laboratory specialist, a logistician, and an epidemiologist/statistician.
Download or read book Tuberculosis Laboratory Biosafety Manual written by World Health Organization and published by . This book was released on 2012 with total page 58 pages. Available in PDF, EPUB and Kindle. Book excerpt: This manual was developed from the Expert Group meeting. The recommendations are based on assessments of the risks associated with different technical procedures performed in different types of TB laboratories; the manual describes the basic requirements for facilities and practices, which can be adapted to follow local or national regulations or as the result of a risk assessment. Risk assessments require careful judgement: on the one hand, underestimating risks may lead to laboratory staff being exposed to biological hazards but, on the other hand, implementing more rigorous risk mitigation measures than are needed may result in an unnecessary burden on laboratory staff and higher costs to establish and maintain the laboratory's infrastructure.
Download or read book WHO operational handbook on tuberculosis Module 3 written by and published by World Health Organization. This book was released on 2021-07-06 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Isolation and Identification of Mycobacterium Tuberculosis written by Bobby E. Strong and published by . This book was released on 1981 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The use of next generation sequencing for the surveillance of drug resistant tuberculosis written by World Health Organization and published by World Health Organization. This book was released on 2023-10-17 with total page 134 pages. Available in PDF, EPUB and Kindle. Book excerpt: This document provides practical guidance on planning and implementing next-generation sequencing (NGS) technology for the characterization of Mycobacterium tuberculosis complex (MTBC) bacteria. The aim is to detect mutations associated with drug resistance in the context of a surveillance system for tuberculosis (TB). This guide is intended to inform staff of national TB programmes and ministries of health, implementing partners, laboratory managers and technical staff, clinicians, donors, and other stakeholders engaged in the surveillance of drug-resistant TB and TB laboratory strengthening.
Download or read book Practical and Laboratory Diagnosis of Tuberculosis written by Guadalupe García-Elorriaga and published by Springer. This book was released on 2015-07-29 with total page 87 pages. Available in PDF, EPUB and Kindle. Book excerpt: The present work focuses on the diagnosis of TB, covering all its possible ways. Content ranges from clinical diagnosis, which is the first instance in approaching tuberculosis, until the gold standard microbiological and molecular diagnostic tools, which are useful due to its speed and high sensitivity. Additionally, diagnosis of latent TB infection, which is key feature to controlling TB under a public health perspective, is also addressed. This book is intended to be a quick and useful reference for the diagnosis of TB, being of special use for clinicians, pulmonologists and microbiologists, but also to every professional, professors and students involved in research and practice on TB diagnosis. In addition, it is intended to be of interest to professionals all over the world, but especially in countries with high TB endemicity, where the proper diagnosis of TB is a topic of major importance.
Download or read book Manual for selection of molecular WHO recommended rapid diagnostic tests for detection of tuberculosis and drug resistant tuberculosis written by and published by World Health Organization. This book was released on 2022-04-28 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Xpert MTB RIF Implementation Manual written by World Health Organization and published by . This book was released on 2015-04-20 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In December 2010, WHO first recommended the use of the Xpert MTB/RIF assay. The WHO's policy statement was supported by a rapid implementation document, which provided the technical "how-to" and operational considerations for rolling out the use of the assay. An unprecedented uptake of this new technology followed the release of WHO's policy: by the end of March 2014, more than 2,300 GeneXpert instruments and more than 6 million Xpert MTB/RIF cartridges had been procured in the public sector in 104 countries eligible for concessional prices. An Expert Group was convened by WHO in May 2013 to review the current body of evidence on use of Xpert MTB/RIF. The resulting recommendations from the Expert Group are included in the WHO Policy update, which widens the recommended use of Xpert MTB/RIF, including for the diagnosis of paediatric TB and on selected specimens for the diagnosis of extrapulmonary TB, and includes an additional recommendation on the use of Xpert MTB/RIF as the initial diagnostic test in all individuals presumed to have pulmonary TB. The accompanying Xpert MTB/RIF implementation manual has been developed to replace the first edition and takes into consideration the current body of evidence and operational experiences available, in the context of the Policy update.
Download or read book Implementation Research in Health written by David H. Peters and published by World Health Organization. This book was released on 2013 with total page 69 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interest in implementation research is growing, largely in recognition of the contribution it can make to maximizing the beneficial impact of health interventions. As a relatively new and, until recently, rather neglected field within the health sector, implementation research is something of an unknown quantity for many. There is therefore a need for greater clarity about what exactly implementation research is, and what it can offer. This Guide is designed to provide that clarity. Intended to support those conducting implementation research, those with responsibility for implementing programs, and those who have an interest in both, the Guide provides an introduction to basic implementation research concepts and language, briefly outlines what it involves, and describes the many opportunities that it presents. The main aim of the Guide is to boost implementation research capacity as well as demand for implementation research that is aligned with need, and that is of particular relevance to health systems in low- and middle-income countries (LMICs). Research on implementation requires the engagement of diverse stakeholders and multiple disciplines in order to address the complex implementation challenges they face. For this reason, the Guide is intended for a variety of actors who contribute to and/or are impacted by implementation research. This includes the decision-makers responsible for designing policies and managing programs whose decisions shape implementation and scale-up processes, as well as the practitioners and front-line workers who ultimately implement these decisions along with researchers from different disciplines who bring expertise in systematically collecting and analyzing information to inform implementation questions. The opening chapters (1-4) make the case for why implementation research is important to decision-making. They offer a workable definition of implementation research and illustrate the relevance of research to problems that are often considered to be simply administrative and provide examples of how such problems can be framed as implementation research questions. The early chapters also deal with the conduct of implementation research, emphasizing the importance of collaboration and discussing the role of implementers in the planning and designing of studies, the collection and analysis of data, as well as in the dissemination and use of results. The second half of the Guide (5-7) detail the various methods and study designs that can be used to carry out implementation research, and, using examples, illustrates the application of quantitative, qualitative, and mixed-method designs to answer complex questions related to implementation and scale-up. It offers guidance on conceptualizing an implementation research study from the identification of the problem, development of research questions, identification of implementation outcomes and variables, as well as the selection of the study design and methods while also addressing important questions of rigor.
Download or read book Nutrition and Health in a Developing World written by Saskia de Pee and published by Humana Press. This book was released on 2017-02-13 with total page 827 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition reviews the epidemiology, policies, programs and outcome indicators that are used to determine improvements in nutrition and health that lead to development. This greatly expanded third edition provides policy makers, nutritionists, students, scientists, and professionals with the most recent and up-to-date knowledge regarding major health and nutritional problems in developing countries. Policies and programs that address the social and economic determinants of nutrition and health are now gaining in importance as methods to improve the status of the most vulnerable people in the world. This volume provides the most current research and strategies so that policy makers, program managers, researchers and students have knowledge and resources that they can use to advance methods for improving the public’s health and the development of nations. The third edition of Nutrition and Health in Developing Countries takes on a new context where the word “developing” is now a verb and not an adjective.
Download or read book Laboratory Biosafety Manual written by World Health Organization and published by . This book was released on 1983 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Guidance for national strategic planning for tuberculosis written by World Health Organization and published by World Health Organization. This book was released on 2022-11-30 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt: A national strategic plan (NSP) for TB is a key document that guides national authorities and stakeholders on how to comprehensively address the TB epidemic through interventions within the health and across other sectors. The NSP translates global, regional and national commitments into national and subnational targets and activities to be implemented to achieve these targets, and provides the basis for mobilizing domestic and external resources for the TB response. It outlines the overall goal(s), strategies and priority interventions, and provides guidance on how these are coordinated across sectors. This guidance is intended for use in developing standalone TB strategic plans, or TB interventions as part of multidisease or health sector plans. It describes key considerations and steps for strategic planning for TB in line with the World Health Organization’s End TB strategy, and the proposed structure of the NSP. The target audience of this publication are all stakeholders involved in national strategic planning for TB (e.g., ministry of health, other government ministries, private sector, civil society, affected communities, academic and research institutions, and technical and funding partners). The current document is an update to the 2015 Toolkit to develop a national strategic plan for TB prevention, care and control. It was developed to better align with global commitments and latest developments in TB and in public health, and builds on lessons learned from using the 2015 toolkit.
Download or read book HIV and Tuberculosis written by Irini Sereti and published by Springer Nature. This book was released on 2019-11-30 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Globally, HIV-associated tuberculosis is one of the most important causes of infection-related death, accounting for one in every three HIV deaths and over 300,000 in 2017 alone. The HIV epidemic has undermined tuberculosis-control efforts in many countries around the world, as the virus has important modifying effects on the pathogenesis, diagnosis, and treatment of TB. The management of HIV-associated TB is also complicated by rapid clinical progression, immune reconstitution inflammatory syndrome, drug-drug interactions, and shared toxicities. The past two decades have yielded thousands of research publications and review articles on HIV-associated TB. HIV and Tuberculosis: A Formidable Alliance consolidates this massive amount of data into a single resource. With contributions from myriad disciplines, including epidemiology, immunology, public health, and clinical medicine, this book provides well-rounded and thorough coverage that will appeal to researchers and clinicians alike.
Download or read book Global Health and Pathology An Issue of the Clinics in Laboratory Medicine written by Dan Milner and published by Elsevier Health Sciences. This book was released on 2018-02-10 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of Clinics in Laboratory Medicine, edited by Dr. Dan Milner, will focus on Global Health and Pathology. Topics include, but are not limited to: Clinical Laboratory Volunteerism, Pathologists Overseas; Anatomic Pathology Volunteerism; Funding Strategies in Research and Global Pathology; Diagnostics for Cancer and Health Systems building through pathology laboratories; Training the next pathologists in global health; Maximizing internet resources for improving pathology/lab medicine in LMICs; Pathology-based research in Africa; HIV and Cancer: Role of Pathology in success; Lymphoma and Pathology in Africa: Current approaches and future diagnostics; Laboratory Capacity as a tool for building health systems; Building Cross Country Networks for Laboratory Capacity and improvement; Lab accreditation; Practical success in Telepathology experiences in Africa; Pathology and WHO vision of the future of LMICs; Breast Cancer in LMICs: Why we need pathology and clinical trial capability to solve this challenge; Cytopathology in LMICs: why and how to integrate to capacitate healthcare; and Biorepositories and Data Cores for Research in Global Health.
