Download or read book Practical Electrophysiological Methods written by Helmut Kettenmann and published by Wiley-Liss. This book was released on 1992-11-11 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed to enable newcomers to electrophysiology to choose appropriate preparations and techniques for in vitro studies in vertebrate neurobiology. Emphasizes techniques involving the glass micropipette and other recently developed methods, supplementing easy-to-follow instructions with illustrative schemes, examples of original records, photomicrographs, key word listings, comprehensive reference tables and a list of suppliers and key equipment and reagents.

Download or read book Introduction to Electrophysiological Methods and Instrumentation written by Franklin Bretschneider and published by Academic Press. This book was released on 2018-11-13 with total page 372 pages. Available in PDF, EPUB and Kindle. Book excerpt: Introduction to Electrophysiological Methods and Instrumentation, Second Edition covers all topics of interest to electrophysiologists, neuroscientists and neurophysiologists, from the reliable penetration of cells and the behavior and function of the equipment, to the mathematical tools available for analyzing data. It discusses the pros and cons of techniques and methods used in electrophysiology and how to avoid pitfalls. Although the basics of electrophysiological techniques remain the principal purpose of this second edition, it now integrates several current developments, including, amongst others, automated recording for high throughput screening and multimodal recordings to correlate electrical activity with other physiological parameters collected by optical means. This book provides the electrophysiologist with the tools needed to understand his or her equipment and how to acquire and analyze low-voltage biological signals. - Introduces possibilities and solutions, along with the problems, pitfalls, and artefacts of equipment and electrodes - Discusses the particulars of recording from brain tissue slices, oocytes and planar bilayers - Describes optical methods pertinent to electrophysiological practice - Presents the fundamentals of signal processing of analogue signals, spike trains and single channel recordings, along with procedures for signal recording and processing - Includes appendices on electrical safety and foundations of useful mathematical tools

Download or read book Basic Electrophysiological Methods written by Ellen Covey and published by Oxford University Press. This book was released on 2015-02-25 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Basic Electrophysiological Methods provides a concise and easy-to-read guide on a selection of the most important contemporary electrophysiological techniques, their implementation, applications, and ways in which they can be combined and integrated with neuroscientific techniques. Intended for students, postdocs, and faculty with a basic neuroscience background, this text will not obscure the relevant technical details with textbook neuroscience tutorials as many other books do. Instead, each chapter provides a conscientious overview of the underlying theory -- a comprehensive description of equipment, materials, methods, data management, and analysis -- a troubleshooting guide, and a list of frequently asked questions. No book or online resource can function as strictly a DIY set of instructions on how to implement a complex technique. However, this book provides a fundamental and accessible set of information intended to form a foundation prior to, during, and after hands-on experience and training, greatly facilitating the initial learning process and subsequent fine-tuning of technical details.

Download or read book Principles and Practice of Clinical Electrophysiology of Vision second edition written by John R. Heckenlively and published by MIT Press. This book was released on 2006-04-07 with total page 1033 pages. Available in PDF, EPUB and Kindle. Book excerpt: The long-awaited second edition of an authoritative reference on electrophysiologic vision testing, including detailed information on techniques and problems, basic physiology and anatomy, theoretical concepts, and clinical findings; with extensive new material. This authoritative text is the only comprehensive reference available on electrophysiologic vision testing, offering both practical information on techniques and problems as well as basic physiology and anatomy, theoretical concepts, and clinical correlations. The second edition, of the widely used text, offers extensive new material and updated information: 65 of the 84 chapters are completely new, with the changes reflecting recent advances in the field. The book will continue to be an essential resource for practitioners and scholars from a range of disciplines within vision science. The contributions not only cover new information—important material that is likely to become more important in the next decade—but also offer a long-range perspective on the field and its remarkable development in the last century. After discussing the history and background of clinical electrophysiology, the book introduces the anatomy of the retina and principles of cell biology in the visual pathways at the molecular, physiological, and biochemical levels. It relates these new findings to the techniques and interpretations of clinical tests, including the electro-oculogram (EOG), electroretinogram (ERG), and visual evoked potentials (VEP), which are discussed in detail, as are equipment, data acquisition and analysis, principles and protocols for clinical testing, diseases and dysfunction, and animal testing. Notable additions for this edition include chapters on the origin of electroretinogram waveforms, multifocal techniques, testing in standard laboratory animals, recent advances in analysis of abnormalities in disease, and the applications of these techniques to the study of genetic abnormalities.

Download or read book Electrophysiological Recording Techniques written by Robert P. Vertes and published by Humana Press. This book was released on 2010-11-19 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Applying neurophysiological methods to the study of brain-behavior relationships proved to be a major advance in the early days of neuroscience research. Considerable technological progress has been made very recently, and the impact on modern neuroscience will be invaluable. In Electrophysiological Recording Techniques, experts in the field present a current view of the widespread application of electrophysiological methods to the study of the brain and to the problem of brain-behavior relationships. The book has been organized to display the range of modern neurophysiological methods ranging from the recordings of single neurons and neuronal ensembles to recordings of field potentials within discrete brain regions and across multiple brain areas. Many of the chapters also address the major challenge of applying the appropriate methods to analyze and interpret neurophysiological recording data. As a volume in the popular Neuromethods series, the chapters provide authoritative reviews of many commonly used approaches in the field today in both the basic research level and in clinical settings. Practical and up-to-date, Electrophysiological Recording Techniques serves as a key reference volume for researchers working in this ever-changing and vital field.

Download or read book Cardiac Electrophysiology Methods and Models written by Daniel C. Sigg and published by Springer Science & Business Media. This book was released on 2010-09-11 with total page 490 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiovascular disease is the major cause of mortality and morbidity in the Western Hemisphere. While significant progress has been made in treating a major sub-category of cardiac disease, arrhythmias, significant unmet needs remain. In particular, every day, thousands of patients die because of arrhythmias in the US alone, and atrial fibrillation is the most common arrhythmia affecting millions of patients in the US alone at a given time. Therefore, there is a public need to continue to develop new and better therapies for arrhythmias. Accordingly, an ever increasing number of biomedical, pharmaceutical, and medical personnel is interested in studying various aspects of arrhythmias at a basic, translational, and applied level, both in industry (ie Biotech, Pharmaceutical and device), and in academia. Not only has our overall understanding of molecular bases of disease dramatically increased, but so has the number of available and emerging molecular, pharmacological or device treatment based therapies. This practical, state-of-the art handbook will summarize and review key research methods and protocols, their advantages and pitfalls, with a focus on practical implementation, and collaborative cross-functional research. The volume will include visual and easy-to-use graphics, bulleted summaries, boxed summary paragraphs, links to reference websites, equipment manufacturers where appropriate, photographs of typical experimental setups and so forth, to keep this book very focused on practical methods and implementation, and yet, provide enough theory that the principles are clearly understood and can be easily applied.

Download or read book Practical Methods in Cardiovascular Research written by Stefan Dhein and published by Springer. This book was released on 2006-02-28 with total page 1011 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientists working or planning to work in the field of cardiovascular research will welcome Methods in Cardiovascular Research as the reference book they have been waiting for. Not only general aspects of cardiovascular research are well presented but also detailed descriptions of methods, protocols and practical examples. Written by leading scientists in their field, chapters cover classical methods such as the Langendorff heart or working heart models as well as numerous new techniques and methods. Newcomers and experienced researchers alike will benefit from the troubleshooting guide in each chapter, the extensive reference lists for advanced reading and the great practical experience of the authors. Methods in Cardiovascular Research is a "must have" for anybody with an interest in cardiovascular research.

Download or read book Handbook of Cardiac Electrophysiology written by Francis D. Murgatroyd and published by Remedica. This book was released on 2002 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text is a comprehensive introductory-level guide to invasive cardiac EP studies. Its focus is to enable the reader to understand and interpret the recording and stimulation techniques used during an EP study.

Download or read book Computer Analysis of Electrophysiological Signals written by John Dempster and published by . This book was released on 1993-01-01 with total page 228 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Volume in the Biological Techniques Series. This essential bench-top manual is the first comprehensive introduction to the principles and practice of the analysis of electrophysiological signals. The text describes hardware and software, including specific techniques for the analysis of single ion channels, noise analysis, and voltage-clamped whole cell currents. Rather than simply providing a manual describing how to use computer programs, this book provides insight into why programs operate in particular ways, the pitfalls awaiting the unwary, and the general philosophy behind signal analysis techniques. Examples of program source code are included. Key Features * Explains the principles of the digitization of analog signals * Provides practical examples for hardware in common use in the electrophysiological laboratory

Download or read book Patch Clamping written by Areles Molleman and published by John Wiley & Sons. This book was released on 2003-06-13 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patch clamping is a widely applied electrophysiological technique for the study of ion channels; membrane proteins that regulate the flow of ions across cellular membranes and therefore influence the physiology of all cells. Patch Clamping aims to cover the basic principles and practical applications of this important technique. Starting with a review of the history of patch clamping, the text then goes on to cover the basic principles, platforms, equipment and environmental control, and will also include coverage of preparation types, recording modes and analysis of results. This book will explain the basic principles and practical application of patch clamp electrophysiology Written in a non-technical style to ensure its broad appeal to novice users Takes a practical approach This self-contained guide provides everything a practising patch clamp electrophysiologist needs to know to master this technique, including an overview of membrane biophysics, standard experimental design, data analysis, and technical concerns

Download or read book Electrophysiological Maneuvers for Arrhythmia Analysis written by George J. Klein MD and published by Cardiotext Publishing. This book was released on 2014-05-01 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: From senior electrophysiologist and world-class educator George Klein, a fully illustrated guide with over 100 intracardiac tracings and figures that allow the physician to approach electrophysiologic problems effectively and systematically. The book is especially focused on electrophysiological maneuvers and provides a clear and understandable guide to their proper selection and interpretation using abundant clinical examples. Defines the integral role for "traditional" electrogram (EGM) analysis in order to understand the mechanism of a tachycardia. It goes without saying that a correct arrhythmia diagnosis is a prerequisite to catheter ablation regardless of the presence of sophisticated mapping and imaging technologies. Electrophysiological maneuvers are fundamental to this process, and proper selection and interpretation of maneuvers constitute a core skill of the electrophysiologist. In this volume, we make the case that most maneuvers are fundamentally similar in principle and can be understood by appreciating a few basic physiological and anatomical principles. The art lies not in a comprehensive knowledge by rote of every maneuver or its application, but rather a systematic approach using common principles. We illustrate this by showing abundant examples and emphasizing the "game plan," including checklists that can be applied to virtually any maneuver. —George J. Klein In my opinion, this book should be on the shelf of every electrophysiologist trainee as well as every clinical cardiac electrophysiologist. It is a classic, like its editor. Dr. Klein deserves high praise for organizing his and his colleagues’ clinical experiences and thought processes into a concise, practical text that should be part of all training programs in electrophysiology. —From the foreword by Mark E. Josephson, MD

Download or read book Practical Intracardiac Echocardiography in Electrophysiology written by Jian-Fang Ren and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tremendous advances in intracardiac echocardiography (ICE) have coincided with the evolution of interventional electrophysiology. This book is designed to provide both the electrophysiologist and echocardiographer with an in-depth view of the role and value of ICE during electrophysiologic procedures. A guide to techniques used for optimal ICE imaging in cardiac electrophysiology is provided. In addition, new and less-recognized uses of ICE in electrophysiological procedures are described and their clinical applications are presented. Illustrated with over 500 images, many of which are in color, the book can also be used as a practical atlas. Readers need not be experts in the field of echocardiography to benefit from this practical approach to intracardiac imaging in electrophysiology.

Download or read book Patch Clamp Electrophysiology written by Mark Dallas and published by Humana. This book was released on 2021-11-13 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume describes a range of standard and novel methodological approaches used to probe ion channel function across different modalities. Chapters guide readers through methods and protocols from an introduction to the decades old patch clamp method for the ion channel neophyte to more complex, recent protocol advances, such as optogenetics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, application details for both the expert and non-expert reader, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Patch Clamp Electrophysiology: Methods and Protocols aims to be a reference guide for current and future ion channel physiologists.

Download or read book Electrophysiological Methods in Biological Research written by Jan Bures and published by Academic Press. This book was released on 2013-10-22 with total page 825 pages. Available in PDF, EPUB and Kindle. Book excerpt: Electrophysiological Methods in Biological Research, Third Revised Edition describes the principles and applications of significant electrophysiological methods as regards to transistorisation of electrophysiological apparatus and to the mathematical analysis of electrophysiological data. The book explains the aspects of physics and electronics that are important in electrophysiology, such as the basic principles of semiconductor function, electronic simulators, electrodes, and the processing of electrophysiological data. The text also cites several examples that measure the resulting membrane potential if one electrode is inside the cell while the other is in contact with the cell's surface. Other experiments show the electrophysiological techniques and the fundamentals of electrical activity in the peripheral excitable structures, and its association with physiological functions. In considering the problems of nerve and muscle physiology, the investigator should know the technique of recording the electrical signs of a nerve impulse. These signs, or action potentials, indicate the presence of a nerve impulse. The text also discusses the effects of barbiturates or ether anesthesia in EEG activity, as well as its dissociation after physostigmine and atropine have been administered. The book can prove useful for pharmacologists, microchemists, cellular biologists, and research workers and technologists dealing with neural mechanisms.

Download or read book Practical Visual Electrophysiological Examination written by Ruifang Sui and published by Springer Nature. This book was released on 2022-04-10 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book includes the concept, general summary and the equipment of the visual electrophysiological examination. It also covers the clinical application scope, diagnosis protocol, standardized operation steps, clinical report samples, and the key points of reading reports, etc. of visual evoked potential (VEP), electroretinogram (ERG), electrooculogram (EOG), multifocal VEP, multifocal ERG and other commonly used visual electrophysiological examinations. Typical clinical report examples of normal and abnormal waveforms are specially added, which is a highlight of this book and can help clinical technicians quickly grasp the key points of electrophysiological report reading.

Download or read book Neurometrics written by E. Roy John and published by Routledge. This book was released on 2021-07-18 with total page 261 pages. Available in PDF, EPUB and Kindle. Book excerpt: Originally published in 1977, this volume attempts to show how the existing state of knowledge and technique in neuroscience can be effectively applied to a variety of practical clinical problems that at the time were dealt with less than adequately. Traditionally, clinical electroencephalography had been one of the major techniques by which our knowledge of neuroscience had been brought to bear upon these problems. The utility of this technique had been sharply limited and constrained by reliance upon qualitative interpretation of electrophysiological observations. In contrast, the approach proposed here is based upon quantitative measurements of salient features extracted from electrophysiological data which reflect various aspects of brain function related to sensory, perceptual and cognitive processes as well as to the structural and functional integrity of different neuroanatomical systems. The Editors call this quantitative approach "neurometrics".

Download or read book Guide to Research Techniques in Neuroscience written by Matt Carter and published by Academic Press. This book was released on 2022-03-26 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern neuroscience research is inherently multidisciplinary, with a wide variety of cutting edge new techniques to explore multiple levels of investigation. This Third Edition of Guide to Research Techniques in Neuroscience provides a comprehensive overview of classical and cutting edge methods including their utility, limitations, and how data are presented in the literature. This book can be used as an introduction to neuroscience techniques for anyone new to the field or as a reference for any neuroscientist while reading papers or attending talks. - Nearly 200 updated full-color illustrations to clearly convey the theory and practice of neuroscience methods - Expands on techniques from previous editions and covers many new techniques including in vivo calcium imaging, fiber photometry, RNA-Seq, brain spheroids, CRISPR-Cas9 genome editing, and more - Clear, straightforward explanations of each technique for anyone new to the field - A broad scope of methods, from noninvasive brain imaging in human subjects, to electrophysiology in animal models, to recombinant DNA technology in test tubes, to transfection of neurons in cell culture - Detailed recommendations on where to find protocols and other resources for specific techniques - "Walk-through" boxes that guide readers through experiments step-by-step