Download or read book Plasma choline and cholinergic mechanisms in the brain methods function and role in Huntington s chorea written by Sven-Åke Eckernäs and published by . This book was released on 1977 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Plasma Choline and Cholinergic Mechanisms in the Brain written by Sven-Åke Eckernäs and published by . This book was released on 1977 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Plasma Choline and Cholinergic Mechanisms in the Brain Methods Function and R le in Huntington s Chorea Akademisk Avhandling written by Sven-Åke Eckernäs and published by . This book was released on 1977 with total page 62 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Choline and Lecithin in Brain Disorders written by André Barbeau and published by . This book was released on 1979 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Some neurological and psychiatric disorders of the brain associated with inadequate cholinergic transmission are being successfully treated with choline and/or lecithin. Plasma composition can affect neurotransmitter synthesis; one function of this phenomenon may be to provide metabolic signals to the brain concerning appetite, stimulus response, or sleepiness. The methods whereby this occurs are being investigated for their possible usefulness in treating manic depression, memory impairment and other brain disorders. Synthesis, biochemistry, measurement, metabolism and dietary sources of choline are discussed, as well as effects and side effects of treatment. Movement disorders, Huntington's disease, dyskinesia, learning and memory are among the brain functions affected by choline being investigated.
Download or read book Brain Acetylcholine and Neuropsychiatric Disease written by Kenneth L. Davis and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent years have witnessed a resurgence of interest in the possible role of brain acetylcholine in neuropsychiatric disease. Research in this area has involved the renewed investigation of the cholinomimetics physostigmine and arecoline, and has been facilitated by the development of new potential cholinomimetics such as dimethylaminoethanol (Deanol) and choline chloride. Current investigators also have taken advantage of new approaches to neurochemical studies. Increasingly sensitive assay techniques such as gas chromatography/mass spectrometry have allowed investigators to measure low concentra tions of choline and acetylcholine in brain tissues. Improved neuroanatomical procedures such as immunohistochemical staining and the use of microelectrodes and micropipets have enabled skilled investigators to begin to map central acetylcholine pathways and to dissect the component parts of the complex interactions between brain acetylcholine and other neurotransmitters. The convergence of data from both clinical and basic studies now suggest that brain acetylcholine may be involved in affective illness, several movement disorders, and some cognitive disturbances. The purpose of this book is to summarize recent clinical and pre-clinical investigations on the possible role of brain acetylcholine in several neurological and psychiatric disorders. The volume is divided into six major sections: (1) Brain Acetylcholine and Psychiatric Disorders; (2) Brain Acetylcholine and Movement Disorders; (3) Brain Acetylcholine and Cognitive Function; (4) The Electrophysiology of Cholinergic Agents; (5) Interactions of Brain Acetylcholine and Other Neurotransmitters; (6) Biochemical and Pharmacological Aspects of CholinergiC Treatment Strategies.
Download or read book Central Cholinergic Mechanisms and Adaptive Dysfunctions written by Man Singh and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although serious interest in studying the role of central cho linergic processes in psychopathology is just beginning to emerge, experimental literature on the part played by cholinergic mechanisms in brain behavior. reiations is quite extensive. During the past thirty years, cholinergic research has contributed significantly to the characterization and differentiation of adaptive mechanisms in volved in input selection, perception, cortical, autonomic and behav ioral activation, learning, memory, and inhibitory control of behav ioral outputs. To say that dysfunction of one or more of these mech anisms may be at the root of neuropsychiatric illnesses such as schiz ophrenia would be stating the obvious. This book examines the part cholinergic processes might play in dysfunctions of the adaptive processes involved in higher brain func tions and their significance for the pathogenesis, classification, etiology, and treatment of psychopathological conditions. In a series of wide ranging reviews of the available information, the subject is discussed from a variety of perspectives, using data derived from both experimental and clinical research. The purpose is not so much to determine whether cholinergic excess or deficiency is causal in this or that neuropsychiatric syndrome, but rather to try to understand the disease mechanisms in terms of adaptive processes in which cholinergic systems seem to play an important part.
Download or read book Exploring the Vertebrate Central Cholinergic Nervous System written by Alexander G. Karczmar and published by Springer Science & Business Media. This book was released on 2007-04-05 with total page 698 pages. Available in PDF, EPUB and Kindle. Book excerpt: Even if the “weapons of mass destruction” (WMD) and, among them, stocks of organoph- phorus (OP) agents (also referred to as war gases and nerve gases) were not found in Iraq following the US-Iraq war, the relative ease with which these substances can be made from harmless precursors and the low cost of their manufacture will continue to fascinate pow- hungry, ruthless dictators, as well as multinational and international terrorists, particularly as the close relationship between the OP agents and useful insecticides makes it easy to disguise the importation and purchase of small amounts of the precursors. Indeed, the use by Saddam Hussein of a nerve gas against the Kurds and his possible employment of the OP agents during his war with Iran, and the Sarin attack in the Tokyo underground by an extremist religious set magnetized the world with respect to the OP drugs. As these drugs exert their toxicity via their cholinergic action on the nervous, particularly central nervous, system, it is no wonder that the research in the cholinergic ? eld attracts, and merits, our intense attention. These considerations underlie the signi? cance of this book, as Alex Karczmar devotes an entire chapter of Exploring the Vertebrate Central Cholinergic Nervous System to anticholinest- ases (antiChEs), and as he is an acknowledged expert in the ? eld of cholinergic toxicity as well as a consultant to the Surgeon General of the U. S. Army.
Download or read book Cumulated Index Medicus written by and published by . This book was released on 1999 with total page 1860 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book CNS Aging and Its Neuropharmacology written by William Meier-Ruge and published by S. Karger AG (Switzerland). This book was released on 1979 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Central Neurotransmitter Turnover written by C. J. Pycock and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: The concept of chemical transmission in the central nervous system has taken some time to be generally accepted, but an increasing number of compounds are now being recognized as hav ing a transmitter role in the brain. The acetylcholine system was the first to be discovered in the periphery and its charac teristic features of storage of transmitter in vesicles in the nerve terminal, its electrically-evoked release and rapid extra neuronal breakdown were considered to be necessary criteria for any neurotransmitter candidate. The subsequent elucidation of the noradrenergic system made it apparent that rapid enzymatic breakdown was not essential for a released transmitter, and the possibility of high-affinity re-uptake processes became establ ished as an alternative means of terminating the synaptic actions of a transmitter. With the eventual acceptance of the amino acids as excitat ory or inhibitory transmitters, the requirement for a transmit ter to be present in a low concentration overall (although locally concentrated in specific terminals) also had to be discarded. This necessitated the additional concept of specif ic metabolic pools with different functions being located in different cells or within different regions of the same cell. Some localization of glutamate and aspartate remote from excit able membranes is clearly essential since their overall brain concentrations would be sufficient to maximally depolarize the majority of neurones in the brain. The concept of separate metabolic pools has been supported by stUdies on turnover rate (see Chapter 5).
Download or read book Neurochemical Transmitters and Modulators written by and published by . This book was released on 1978 with total page 616 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Biogenic Amines and Transmitters in the Nervous System written by and published by . This book was released on 1977 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Parkinson s Disease and Related Disorders written by and published by . This book was released on 1977 with total page 714 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Acta Neurologica Scandinavica written by and published by . This book was released on 1962 with total page 1294 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Perspectives in Psychopharmacology written by Earl Usdin and published by . This book was released on 1988 with total page 728 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Nutritional Factors written by Roland F. Beers and published by Lippincott Williams & Wilkins. This book was released on 1981 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt:
