Download or read book Phytochemistry Computational Tools and Databases in Drug Discovery written by Chukwuebuka Egbuna and published by Elsevier. This book was released on 2022-11-30 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phytochemistry, Computational Tools and Databases in Drug Discovery presents the state-of-the-art in computational methods and techniques for drug discovery studies from medicinal plants. Various tools and databases for virtual screening and characterization of plant bioactive compounds and their subsequent predictions on biological targets for the discovery of new drugs against specific diseases are presented, along with computational tools for the prediction of the toxic effects of phytochemicals on living systems. The book also provides in-depth insight on the applications of these computational tools as well as the databases that describe the interactions of phytochemicals with diseases along with predictions for druggable bioactive compounds. Useful for drug developers, medicinal chemists, toxicologists, phytochemists, plant biochemists and analytical chemists, this book clearly presents the various computational techniques, tools and databases for phytochemical research. Provides the various databases, methods and procedures for computational drug discovery in plants Includes insights into the predictors for properties of phytochemicals against different diseases Discusses the applications of computational tools and their databases

Download or read book Textbook of Pharmacognosy Phytochemistry written by Dr Biren Shah and published by Elsevier India. This book was released on 2013-11-01 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive textbook primarily aims at fulfilling the syllabus requirements of B.Pharm. students. It is specifically designed to impart knowledge about the alternative systems of medicine and modern pharmacognosy. Additionally, it will also serve as a valuable information resource to other health sciences students and researchers working in the field of herbal technology.

Download or read book Herbalism Phytochemistry and Ethnopharmacology written by Amritpal Singh and published by CRC Press. This book was released on 2011-04-11 with total page 440 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bridging the gap between the ancient art of herbalism and the emerging sciences of ethnopharmocology and phytopharmacotherapy, this book highlights the major breakthroughs in the history of the field and focuses on future directions in the discovery and application of herb-derived medicines. Implementing the concept of reverse pharmacology, it inte

Download or read book Phytochemistry An in silico and in vitro Update written by Shashank Kumar and published by Springer. This book was released on 2019-06-25 with total page 575 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phytochemistry is the branch of science that deals with the study of plant-derived chemicals or compounds, which are also known as phytochemicals or plant-derived secondary metabolites. Plants are known to produce phytochemicals that are essential for their growth and reproduction, as they protect them from insects, pathogens, and herbivores. Some of the major groups of plant-derived secondary metabolites are phenolics, flavonoids, terpenoids, alkaloids, tannin etc. Plant-derived phytochemicals are pharmacologically active and have the potential to cure various human diseases and disorders. Natural plant products have been known for their medicinal properties for untold years, and form the basis of several medicinal systems such as Chinese, Unani, and Ayurvedic Medicine. This book offers an essential introduction to phytochemicals and their synthetic analogues. It discusses various in silico approaches used to identify pharmacologically active phytochemicals and their biological activities, as well as in vitro and in vivo models/assays that have been utilized for the pharmacological profiling of plant-derived products to combat cancer, diabetes, cardiovascular diseases and neurological disorders. The intended audience includes upper-level undergraduate and graduate students; researchers and scientists from the pharmaceutical/food chemistry/nutrition sciences/biochemistry, and clinical biochemistry fields; and medical students. Sharing the latest findings, the book will familiarize these readers with the concepts, chemistry, and tremendous potential of phytochemistry.

Download or read book Computational Phytochemistry written by Satyajit Dey Sarker and published by Elsevier. This book was released on 2024-03-15 with total page 532 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Phytochemistry, Second Edition, explores how recent advances in computational techniques and methods have been embraced by phytochemical researchers to enhance many of their operations, refocusing and expanding the possibilities of phytochemical studies. By applying computational aids and mathematical models to extraction, isolation, structure determination, and bioactivity testing, researchers can obtain highly detailed information about phytochemicals and optimize working approaches. This book aims to support and encourage researchers currently working with or looking to incorporate computational methods into their phytochemical work. Topics in this book include computational methods for predicting medicinal properties, optimizing extraction, isolating plant secondary metabolites, and building dereplicated phytochemical libraries. The roles of high-throughput screening, spectral data for structural prediction, plant metabolomics, and biosynthesis are all reviewed before the application of computational aids for assessing bioactivities and virtual screening is discussed. Illustrated with detailed figures and supported by practical examples, this book is an indispensable guide for all those involved with the identification, extraction, and application of active agents from natural products. This new edition captures remarkable advancements in mathematical modeling and computational methods that have been incorporated in phytochemical research, addressing, e.g., extraction, isolation, structure determination, and bioactivity testing of phytochemicals. Includes step-by-step protocols for various computational and mathematical approaches applied to phytochemical research Features clearly illustrated chapters contributed by highly reputable researchers Covers all key areas in phytochemical research, including virtual screening and metabolomics

Download or read book Phytochemistry the Military and Health written by Andrew G. Mtewa and published by Elsevier. This book was released on 2021-03-02 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phytochemistry, the Military and Health: Phytotoxins and Natural Defenses comes as a response to the gap that there has for so long existed between phytochemistry and survival of both service personnel and civilian communities during and after conflicts. Armed conflicts cause a lot of devastation to communities and should be avoided as much as it can be possible. The devastation is usually evident in service provisions such as Health, Education, Water, and Food among many others. Both service personnel and civilians are affected to various degrees. Facilities usually end up being physically destroyed, with no essential supplies and/or having dysfunctional systems. Going with untreated wounds, communicable and non-communicable diseases for weeks with no medical interventions due to the conflicts, disease burdens heavily weigh down on communities as well as security personnel. To make the situation even more complicated, masses of people are forced to migrate for safety and security reasons, likely going with diseases along wherever they go. In such instances, phytochemicals become handy in providing solutions from first aid, basic analgesia, antimicrobials, and the general improvement of health. Phytochemicals are known to play a major role in the day to day management of diseases and health. There has been much research into their effectiveness as community medicines and as alternatives to conventional drugs. However, the role that phytochemicals play in the military, counterterrorism, and security has been overlooked. Phytochemistry, the Military and Health: Phytotoxins and Natural Defenses discusses the roles that phytochemicals play as friends and foes in the military, including insights aimed to help develop antidotes against phytochemicals and other chemical agents used maliciously as weapons. Filling a gap between drug discovery, security, and emergency medicine, this book describes which plants can be categorized for protection and controls, which can be helpful in times of conflicts and soon after conflicts, in military operations, and those that can be used as deterrents and as emergency medicines. Carefully designed to show the contribution that phytochemicals play in safety and security, this book is useful for researchers, regulators and anyone interested in plant chemistry. Covers the contribution that phytochemicals play in safety and security Contains insights that will help in the development of antidotes against phytochemical and other chemical weapons Categorizes plants in terms of their usefulness as well as the potential security risks they possess

Download or read book Phytochemistry of Medicinal Plants written by John T. Arnason and published by Springer Science & Business Media. This book was released on 2013-11-11 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Phytochemicals from medicinal plants are receiving ever greater attention in the scientific literature, in medicine, and in the world economy in general. For example, the global value of plant-derived pharmaceuticals will reach $500 billion in the year 2000 in the OECD countries. In the developing countries, over-the-counter remedies and "ethical phytomedicines," which are standardized toxicologically and clinically defined crude drugs, are seen as a promising low cost alternatives in primary health care. The field also has benefited greatly in recent years from the interaction of the study of traditional ethnobotanical knowledge and the application of modem phytochemical analysis and biological activity studies to medicinal plants. The papers on this topic assembled in the present volume were presented at the annual meeting of the Phytochemical Society of North America, held in Mexico City, August 15-19, 1994. This meeting location was chosen at the time of entry of Mexico into the North American Free Trade Agreement as another way to celebrate the closer ties between Mexico, the United States, and Canada. The meeting site was the historic Calinda Geneve Hotel in Mexico City, a most appropriate site to host a group of phytochemists, since it was the address of Russel Marker. Marker lived at the hotel, and his famous papers on steroidal saponins from Dioscorea composita, which launched the birth control pill, bear the address of the hotel.

Download or read book Phytochemistry written by Chukwuebuka Egbuna and published by CRC Press. This book was released on 2018-12-12 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first book in this three-volume set provides comprehensive coverage of a wide range of topics in phytochemistry. With chapters from professional specialists from key institutions around the world, the volume starts with an introduction to phytochemistry and details the fundamentals. Part II discusses the state-of-the-art modern methods and techniques in phytochemical research, while Part III provides an informative overview of computational phytochemistry and its applications. Part IV presents novel research findings in the discovery of drugs that will be effective in the treatment of diseases. The chapters are drawn carefully and integrated sequentially to aid flow, consistency, and continuity.

Download or read book Phytochemistry of Plants of Genus Piper written by Brijesh Kumar and published by CRC Press. This book was released on 2020-06-08 with total page 78 pages. Available in PDF, EPUB and Kindle. Book excerpt: Piper is the representative genus of family Piperaceae. Piper species are pan-tropical in distribution and found in both the hemispheres. As the king of all spices, black pepper, Piper nigrum, led to the global expeditions culminating in the discovery of India and the new world. Piper species have been reported to possess various pharmacological activities such as insecticidal, antibacterial, anti-inflammatory, antiplatelet, anti-hypertensive, antithyroid, antitumor activities and hepatoprotective properties. Botanical authentication of the plants of Piper species is difficult because of the morphological similarity among the species. This book describes ultra-performance liquid chromatography coupled with triple quadrupole electrospray tandem mass spectrometry in multiple reactions monitoring (MRM) mode to study the quantitative variation of thirteen bioactive markers in different plant parts of ten Piper species. Features: Collection of Ayurvedic features and scientific evidence of the most important medicinal plants of Piper species. Describes chemical signatures for identification of Piper species. Provides easy-to-use analytical procedure for quality control of Piper species and its products.

Download or read book Plant Biochemistry written by Hans-Walter Heldt and published by Academic Press. This book was released on 2005 with total page 658 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1 A Leaf Cell Consists of Several Metabolic Compartments 2 The Use of Energy from Sunlight by Photosynthesis is the Basis of Life on Earth 3 Photosynthesis is an Electron Transport Process 4 ATP is Generated by Photosynthesis 5 Mitochondria are the Power Station of the Cell 6 The Calvin Cycle Catalyzes Photosynthetic CO2 Assimilation 7 In the Photorespiratory Pathway Phosphoglycolate Formed by the Oxygenase Activity of RubisCo is Recycled 8 Photosynthesis Implies the Consumption of Water 9 Polysaccharides are Storage and Transport Forms of Carbohydrates Produced by Photosynthesis 10Nitrate Assimilation is Essential for the Synthesis of Organic Matter 11 Nitrogen Fixation Enables the Nitrogen in the Air to be Used for Plant Growth 12 Sulfate Assimilation Enables the Synthesis of Sulfur Containing Substances 13 Phloem Transport Distributes Photoassimilates to the Various Sites of Consumption and Storage 14 Products of Nitrate Assimilation are Deposited in Plants as Storage Proteins 15 Glycerolipids are Membrane Constituents and Function as Carbon Stores 16 Secondary Metabolites Fulfill Specific Ecological Functions in Plants 17 Large Diversity of Isoprenoids has Multiple Funtions in Plant Metabolism 18 Phenylpropanoids Comprise a Multitude of Plant Secondary Metabolites and Cell Wall Components 19 Multiple Signals Regulate the Growth and Development of Plant Organs and Enable Their Adaptation to Environmental Conditions 20 A Plant Cell has Three Different Genomes 21 Protein Biosynthesis Occurs at Different Sites of a Cell 22 Gene Technology Makes it Possible to Alter Plants to Meet Requirements of Agriculture, Nutrition, and Industry.

Download or read book Integrative Phytochemistry from Ethnobotany to Molecular Ecology written by John Romeo and published by Elsevier. This book was released on 2003-07-23 with total page 340 pages. Available in PDF, EPUB and Kindle. Book excerpt: This monograph series is commissioned by the Phytochemical Society of North America (PSNA). The volumes in this series contain articles on developing topics of interest to scientists, students and individuals interested in recent developments in the biochemistry, chemistry and molecular biology of plants. Volume 37 concentrates on the integration of techniques to solve complex phytochemistry problems. This volume describes the combination of multiple techniques to solve complex plant science problems. The chapters investigate What, Why and How secondary metabolites are formed. Volume 37 covers a wide range of phytochemistry topics from Ethnobotany to Molecular ecology.

Download or read book Phytochemistry of Plants of Genus Rauvolfia written by Brijesh Kumar and published by CRC Press. This book was released on 2020-06-08 with total page 79 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rauvolfia species, commonly known as Sarpagandha, has been traditionally used in Ayurveda for curing high blood pressure, hypertension, snake bites, fever, and mental illnesses. Due to its wide variety and differences in chemical composition, it is necessary to develop an efficient and reliable method for rapid screening and determination of phytochemicals in the extracts of the Rauvolfia species. This book will provide qualitative and quantitative comparative phytochemical investigations of selected medicinal plants from the Rauvolfia genus using liquid chromatography-mass spectrometry (LC-MS) techniques. The results will help in assuring the efficacy and safety of Rauvolfia herbal products. Features: Collection of Ayurvedic features and scientific evidence of important medicinal plants. Discusses chemical signatures for the identification of Rauvolfia (Sarpagandha) and its products. Easy-to-use analytical procedure for quality control of Rauvolfia and its products.

Download or read book Phytochemistry of Plants of Genus Phyllanthus written by Brijesh Kumar and published by CRC Press. This book was released on 2021-12-31 with total page 89 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book deals with the importance of separation techniques in screening of major lignans, flavonoids and terpenoids in Phyllanthus species using HPLC/UPLC coupled with mass spectrometric techniques.

Download or read book Thin Layer Chromatography in Phytochemistry written by Monika Waksmundzka-Hajnos and published by CRC Press. This book was released on 2008-03-04 with total page 898 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thin layer chromatography (TLC) is increasingly used in the fields of plant chemistry, biochemistry, and molecular biology. Advantages such as speed, versatility, and low cost make it one of the leading techniques used for locating and analyzing bioactive components in plants. Thin Layer Chromatography in Phytochemistry is the first sourc

Download or read book Ecological Biochemistry written by Gerd-Joachim Krauss and published by John Wiley & Sons. This book was released on 2015-01-12 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first stand-alone textbook for at least ten years on this increasingly hot topic in times of global climate change and sustainability in ecosystems. Ecological biochemistry refers to the interaction of organisms with their abiotic environment and other organisms by chemical means. Biotic and abiotic factors determine the biochemical flexibility of organisms, which otherwise easily adapt to environmental changes by altering their metabolism. Sessile plants, in particular, have evolved intricate biochemical response mechanisms to fit into a changing environment. This book covers the chemistry behind these interactions, bottom up from the atomic to the system's level. An introductory part explains the physico-chemical basis and biochemical roots of living cells, leading to secondary metabolites as crucial bridges between organisms and the respective ecosystem. The focus then shifts to the biochemical interactions of plants, fungi and bacteria within terrestrial and aquatic ecosystems with the aim of linking biochemical insights to ecological research, also in human-influenced habitats. A section is devoted to methodology, which allows network-based analyses of molecular processes underlying systems phenomena. A companion website offering an extended version of the introductory chapter on Basic Biochemical Roots is available at http://www.wiley.com/go/Krauss/Nies/EcologicalBiochemistry

Download or read book Phytochemical Methods written by Jeffrey B. Harborne and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: While there are many books available on methods of organic and biochemical analysis, the majority are either primarily concerned with the application of a particular technique (e.g. paper chromatography) or have been written for an audience of chemists or for biochemists work ing mainly with animaltissues. Thus, no simple guide to modern metho ds of plant analysis exists and the purpose of the present volume is to fill this gap. It is primarily intended for students in the plant sciences, who have a botanical or a general biological background. It should also be of value to students in biochemistry, pharmacognosy, food science and 'natural products' organic chemistry. Most books on chromatography, while admirably covering the needs of research workers, tend to overwhelm the student with long lists of solvent systems and spray reagents that can be applied to each class of organic constituent. The intention here is to simplify the situation by listing only a few specially recommended techniques that have wide currency in phytochemical laboratories. Sufficient details are provided to allow the student to use the techniques for themselves and most sections contain some introductory practical experiments which can be used in classwork.

Download or read book Phytochemistry of Plants of Genus Cassia written by Brijesh Kumar and published by CRC Press. This book was released on 2021-08-12 with total page 82 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cassia is an indigenous plant in Africa, Latin America, Northern Australia and Southeast Asia. Several Cassia species are of high commercial and medicinal significance since they are used as spices and in traditional medicines. Currently plants from genus Cassia is in great demand due to their immense medicinal properties. Cassia species have various pharmacological activities such as antibacterial, analgesic, antiinflammatory, antiarthritic, hepatoprotective, antitumor, antifertility, antifungal, antioxidant, antileishmaniatic, antimicrobial, CNS and hypoglycaemic activitiy. Different class of compounds reported from Cassia species are anthraquinones, phenolics, flavonoids, chromenes, terpenes, proanthocyanidins, coumarins, chromones and lignans. The taxonomy and nomenclature of Cassia species are quite complex. It is very difficult to differentiate them due to their overlapping morphological characters and close similarities. This usually leads to misidentification and misinterpretation of the components. Features: Presents collection of Ayurvedic features and scientific evidence of most important medicinal plants of Cassia species Chemical signatures for identification of Cassia species Easy to use analytical procedure for quality control of Cassia species and its products.