Download or read book Physiologic and Chemical Basis for Metal Toxicity written by B. Venugopal and published by Springer. This book was released on 1977-01-01 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our purpose is to provide understanding for appropriate use of metals in a technical society. Knowledge of metal toxicity is needed for the preven tion, prediction, diagnosis, and therapy of adverse reactions from excess metals in mammals. Metal Toxicity in Mammals is presented in two volumes. Volume 1, Physiologic and Chemical Basis for Metal Toxic ity, provides the basis for understanding the toxic actions of metals recorded in Volume 2, Chemical Toxicity of Metals and Metalloids. The details and bases for many concepts summarized in Volume I are given, with appropriate references, in Volume 2. Thus, references for specific items in Volume 2 are not generally given in Volume 1. The authors reviewed the known toxicity of several heavy metals in anticipation of their use as multinutrient markers for NASA. As more and more metals were considered, the need for a complete review became obvious. This treatise supplants onerous searches of metal-toxicity litera ture up to 1975 and reviews the toxicity of all the metals of the periodic table on the basis of available relevant data. Books on pharmacological, nutritional, medical, veterinary, or industrial toxicity contain information about selected metals. More complete data about metals of public concern, such as mercury, lead, and cadmium, may be found in numerous books and reviews. The reader should refer to general texts and basic reference works, when specific references are not given, for general information.

Download or read book Physiologic and Chemical Basis for Metal Toxicity written by B. Venugopal and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: Our purpose is to provide understanding for appropriate use of metals in a technical society. Knowledge of metal toxicity is needed for the preven tion, prediction, diagnosis, and therapy of adverse reactions from excess metals in mammals. Metal Toxicity in Mammals is presented in two volumes. Volume 1, Physiologic and Chemical Basis for Metal Toxic ity, provides the basis for understanding the toxic actions of metals recorded in Volume 2, Chemical Toxicity of Metals and Metalloids. The details and bases for many concepts summarized in Volume I are given, with appropriate references, in Volume 2. Thus, references for specific items in Volume 2 are not generally given in Volume 1. The authors reviewed the known toxicity of several heavy metals in anticipation of their use as multinutrient markers for NASA. As more and more metals were considered, the need for a complete review became obvious. This treatise supplants onerous searches of metal-toxicity litera ture up to 1975 and reviews the toxicity of all the metals of the periodic table on the basis of available relevant data. Books on pharmacological, nutritional, medical, veterinary, or industrial toxicity contain information about selected metals. More complete data about metals of public concern, such as mercury, lead, and cadmium, may be found in numerous books and reviews. The reader should refer to general texts and basic reference works, when specific references are not given, for general information.

Download or read book Metal Toxicity in Mammals Physiologic and chemical basis for metal toxicity written by Thomas D. Luckey and published by . This book was released on 1977 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Chelation Therapy in the Treatment of Metal Intoxication written by Jan Aaseth and published by Academic Press. This book was released on 2016-04-18 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chelation Therapy in the Treatment of Metal Intoxication presents a practical guide to the use of chelation therapy, from its basic chemistry, to available chelating antidotes, and the application of chelating agents. Several metals have long been known to be toxic to humans, and continue to pose great difficulty to treat. These challenges pose particular problems in industrial settings, with lead smelting known to be associated with hemopoietic alterations and paralyses, and the inhalation of mercury vapor in mercury mining being extremely detrimental to the central nervous system. Clinical experience has demonstrated that acute and chronic human intoxications with a range of metals can be treated efficiently by administration of chelating agents. Chelation Therapy in the Treatment of Metal Intoxication describes the chemical and biological principles of chelation in the treatment of these toxic metal compounds, including new chelators such as meso-2,3-dimercaptosuccinic acid (DMSA) and D,L-2,3-dimercapto-1-propanesulfonic acid (DMPS). - Presents all the current findings on the potential for chelation as a therapy for metal intoxication - Presents practical guidelines for selecting the most appropriate chelating agent - Includes coverage on radionuclide exposure and metal storage diseases - Describes the chemical and biological principles of chelation in the treatment of toxic metal compounds

Download or read book Cellular Effects of Heavy Metals written by Gaspar Banfalvi and published by Springer Science & Business Media. This book was released on 2011-03-02 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term “heavy metals” is used as a group name of toxic metals and metalloids (semimetals) causing contaminations and ecotoxicity. In strict chemical sense the density of heavy metals is higher than 5 g/cm3. From biological point of view as microelements they can be divided into two major groups. a. For their physiological function organisms and cells require essential microelements such as iron, chromium (III), cobalt, copper, manganese, molidenium, zinc. b. The other group of heavy metals is toxic to the health or environment. Of highest concern are the emissions of As, Cd, Co, Cu, Hg, Mn, Ni, Pb, Sn, Tl. The toxicity of heavy metals is well known at organizational level, while less attention has been paid to their cellular effects. This book describes the toxicity of heavy metals on microorganisms, yeast, plant and animal cells. Other chapters of the book deal with their genotoxic, mutagenic and carcinogenic effects. The toxicity of several metals touch upon the aspects of environmental hazard, ecosystems and human health. Among the cellular responses of heavy metals irregularities in cellular mechanisms such as gene expression, protein folding, stress signaling pathways are among the most important ones. The final chapters deal with biosensors and removal of heavy metals. As everybody is eating, drinking and exposed to heavy metals on a daily basis, the spirit of the book will attract a wide audience.

Download or read book Poisoning in the Modern World written by Ozgur Karcioglu and published by BoD – Books on Demand. This book was released on 2019-06-19 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 400 years ago, Swiss alchemist and physician Paracelsus (1493-1541) cited: "All substances are poisons; there is none that is not a poison. The right dose differentiates a poison from a remedy." This is often condensed to: "The dose makes the poison." So, why are we overtly anxious about intoxications?In fact, poisons became a global problem with the industrial revolution. Pesticides, asbestos, occupational chemicals, air pollution, and heavy metal toxicity maintain high priority worldwide, especially in developing countries. Children between 0 and 5 years old are the most vulnerable to both acute and chronic poisonings, while older adults suffer from the chronic effects of chemicals. This book aims to raise awareness about the challenges of poisons, to help clinicians understand current issues in toxicology.

Download or read book Plant Metallomics and Functional Omics written by Gaurav Sablok and published by Springer. This book was released on 2019-07-04 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Major portion of the planet earth is covered by seas and oceans representing 96.5% of the planet’s water, playing a detrimental role in sustaining the plant including crop diversity and productivity for human consumption. Water resources contain both soluble and transition metals, which are easily absorbed by plants through roots as a first point of contact and subsequently play important physiological and biological functions in plants. Transition metals such as copper (Cu), iron (Fe), manganese (Mn) and zinc (Zn) contribute to the plant productivity by playing key functional roles in the photosynthesis. In addition, to their major role in regulating the plant productivity, they also play an important role by acting as homeostatic regulators in uni-parentally inherited chloroplasts and maintains the flow of the electron transfer. It is worthwhile to mention that they play a critical role as transporters, which acts as electron balancing units for managing the electrostatic potential across the membranes. In contrast, some metals such as Cd, As play a significant role in inducing the stress mechanism and influencing either directly or in-directly Haber-Weiss reactions either through the production of the reactive oxygen species (ROS) or through the membrane damage thus leading to leakage of membrane transporters. However, besides playing a detrimental role as transporters in plant system, excessive accumulation of these metals due to the increasing contamination in the marginal soil and water are posing important threats to the plant system. Realizing the toxic effects of the metals, several physiological evidences have been laid for the credence of the metal toxicity and their concurrent effect on plant productivity. Increasing effects of the metals as toxicants can have three adverse effects on the populations: population can move, persist via local adaptation or phenotypic plasticity, or die. Next generation sequencing studies have revolutionized our abilities to detect the changes in expression profiles across an array of genes, which can in-turn help to develop early markers of metal induced stress. Plant Metallomics and Functional Omics: A System-Wide Perspective focuses on the applications of the system wide understanding of the biological and functional interplay occurring at the juncture of the metalloid induced stress and toxicity. The main goal of this book is to familiarize the readers with the most up-to-date information on metal-induced physiological changes in plant species.

Download or read book Metal Chelation in Medicine written by Robert R Crichton and published by Royal Society of Chemistry. This book was released on 2016-10-18 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metal chelators are emerging as versatile tool with many medical applications. Their versatility allows them to be used in chelation therapy for treating diseases caused by toxic and heavy metal poisoning, chelating agents are capable of binding to toxic metal ions to form complex structures which are easily excreted from the body removing them from intracellular or extracellular spaces. In addition, metal chelators can also be applied as contrast agents in MRI scanning. Metal Chelation in Medicine provides a clear and timely perspective on the role of chelating agents in the management of metal intoxications and storage diseases. Written by leaders in the field of chelators, this publication is at the cutting-edge of the subject. It covers a broad range of topics such as the use of metal chelators in non-invasive assessment of brain iron overload, and the treatment of systemic iron overload and neurodegenerative diseases. As such it is particularly valuable to clinicians treating metal poisonings and metal storage diseases. However, it is also a useful text for researchers, industry professionals and university students with a specific interest in medicinal chemistry, chelation, metal ions, imaging and non-invasive techniques.

Download or read book Biochemical Toxicology written by Muharrem Ince and published by BoD – Books on Demand. This book was released on 2020-07-29 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical Toxicology - Heavy Metals and Nanomaterials provides an overview of biochemical contamination, nanomaterials and toxic metals, and measurement techniques. It explains and clarifies important studies and compares and develops new and groundbreaking measurement techniques in the fields of organic and inorganic pollution and nanoscience. It is highly recommended for professionals and readers interested in the environment and human health.

Download or read book Diet and Health written by National Research Council and published by National Academies Press. This book was released on 1989-01-01 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.

Download or read book Plants and Heavy Metals written by Antonella Furini and published by Springer Science & Business Media. This book was released on 2012-04-23 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title focuses on the many aspects of the interaction between plants and heavy metals. Not only it describes the effects of heavy metal toxicity on the plant cell and its organs but it also examines the mechanisms that plants adopt to scavenge heavy metals at cellular, physiological, and metabolic level. Plants and Heavy Metals also analyses Hyperaccumulator plants and shows their potential role in phytoremediation technologies in light of the recent research results.

Download or read book Plant Metal Interaction written by Parvaiz Ahmad and published by Elsevier. This book was released on 2016-02-02 with total page 654 pages. Available in PDF, EPUB and Kindle. Book excerpt: Plant Metal Interaction: Emerging Remediation Techniques covers different heavy metals and their effect on soils and plants, along with the remediation techniques currently available. As cultivable land is declining day-by-day as a result of increased metals in our soil and water, there is an urgent need to remediate these effects. This multi-contributed book is divided into four sections covering the whole of plant metal interactions, including heavy metals, approaches to alleviate heavy metal stress, microbial approaches to remove heavy metals, and phytoremediation. - Provides an overview of the effect of different heavy metals on growth, biochemical reactions, and physiology of various plants - Serves as a reference guide for available techniques, challenges, and possible solutions in heavy metal remediation - Covers sustainable technologies in uptake and removal of heavy metals

Download or read book National Library of Medicine Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1993 with total page 690 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.

Download or read book The Responses of Plants to Metal Toxicity written by S.M. Reichman and published by . This book was released on 2002 with total page 59 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Chemical Exposure and Toxic Responses written by Stephen K. Hall and published by CRC Press. This book was released on 2020-07-24 with total page 299 pages. Available in PDF, EPUB and Kindle. Book excerpt: Providing material for practitioners and students alike, Chemical Exposure and Toxic Responses is a clear and straightforward presentation of industrial toxicology. Exposure to toxic chemicals is of major concern to health professionals. In recent years, the scope and importance of hazardous materials toxicology has expanded and now impacts financial institutions, government, private corporations, and many other organizations as well. Chemical Exposure and Toxic Responses presents the myriad health implications of hazardous chemicals in a single source. This book is organized so that readers can proceed from a general perspective on the problem of chemical exposure and toxic responses to an understanding of toxicology and a method of inquiry. Written for anyone who needs practical toxicological information, the book compactly and efficiently presents the scientific basis of toxicology as it applies to the workplace. It covers the diverse chemical hazards encountered in the work environment and provides a practical understanding of these hazards for those charged with protecting the health and well being of people at work. Chemical Exposure and Toxic Responses consists of three parts: Part I establishes the general principles of industrial toxicology; Part II addresses specific effects of toxic agents on specific physiological organs and systems; and Part III is devoted to the evaluation of hazards in the workplace.

Download or read book Basics of Toxicology written by Chris Kent and published by John Wiley & Sons. This book was released on 1998-11-13 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt: Toxicology--the scientific study of environmental factors that are harmful to living organisms--was established more than 400 years ago by the Swiss physician Paracelsus. Yet, despite its long lineage, this fascinating discipline continues to evolve sophisticated new tools and techniques for identifying toxins and the means by which they impair health. This book provides environmental technology students with an enjoyable and effective way to acquire the solid working knowledge of toxicology basics they'll need to make informed decisions as professionals. Features that make Basics of Toxicology an ideal introduction to the subject for two-year and four-year environmental technology students, include: * Acclaimed, user-friendly, modular format found in all the books in the Preserving the Legacy series * Basic anatomy, physiology, and chemistry concepts that help clarify how toxins interact with living tissue * Rapid-learning chapter structure, featuring clear, concise objectives, concept statements, and summaries, as well as practice questions * Helpful sidebars that highlight critical concepts * More than 150 high-quality line-drawings, photographs, diagrams, charts, and tables * Numerous easy-to-perform, skill-building activities * A glossary of more than 800 essential terms * Extensive bibliography of recommended readings in all key subject areas * Basic anatomy, physiology, and chemistry concepts that help clarify how toxins interact with living tissue Its comprehensive scope along with its quick-reference design also makes Basics of Toxicology a handy working reference for practicing environmental technicians.

Download or read book Metal Transporters written by Jose M. Arguello and published by Academic Press. This book was released on 2012-10-25 with total page 478 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Current Topics in Membranes focuses on metal transmembrane transporters and pumps, a recently discovered family of membrane proteins with many important roles in the physiology of living organisms. The book summarizes the most recent advances in the field of metal ion transport and provides a broad overview of the major classes of transporters involved in homeostasis of heavy metals. Various families of the transporters and metal specificities are discussed with the focus on the structural and mechanistic aspects of their function and regulation. The reader will access information obtained through a variety of approaches ranging from X-ray crystallography to cell biology and bioinformatics, which have been applied to transporters identified in diverse biological systems, such as pathogenic bacteria, plants, humans and others. Field is cutting-edge and a lot of the information is new to research community Wide breadth of topic coverage Contributors of high renown and expertise