Download or read book Physical Forces and the Mammalian Cell written by Bozzano G Luisa and published by Academic Press. This book was released on 2012-12-02 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the physical forces - fluid shear, stretch, and gravity that play a role in the physiology of tissues and cellular functions. It gives special attention to the influences of the flow of blood and exercise on the growth of blood vessels and the flow of interstitial fluid on bone formation. Pathological conditions are also presented, such as the lack of mechanical loading on bone and osteoporosis. For biotechnologists, the problem of cell susceptibility to agitation-induced hydrodynamic forces in the scale-up of mammalian cell bioreactors is examined.
Download or read book Mechanical Forces Their Effects on Cells and Tissues written by Keith J. Gooch and published by Springer Science & Business Media. This book was released on 2013-03-14 with total page 230 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Cell Culture nimal cell culture began in 1912 when Alexis Carrel grew bits of chick heart A in vitro by placing them into a drop of horse plasma. When the plasma clotted, it formed a solid surface into which the heart cells explanted. Left unattended, these cells died within several days. By regularly feeding the grow ing cells with aqueous extracts of whole chick embryos and periodically sub dividing them, Carrel was able to maintain the cells for extended periods. From these initial experiments, cell culture has expanded into an important component of biological research and commercial production. Animal cell culture is an important tool for the study of complex biologi cal systems. In vivo it is often impossible to target a treatment to one specific cell type or to adequately control the environment. For example, it is impos sible to selectively depolarize endothelial cells in vivo to determine the role of transmembrane potential in the transduction of fluid mechanical forces generated by blood flow to a biochemical response. Depolarizing all of the cells within the vascular system by injecting potassium chloride into the animal's bloodstream clearly is not an option, as it will lead to cardiac arrest.
Download or read book Mechanical Forces written by Keith J. Gooch and published by . This book was released on 1997-01-01 with total page 182 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Cellular Mechanotransduction written by Mohammad R. K. Mofrad and published by Cambridge University Press. This book was released on 2014-07-31 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Mechanotransduction" is the term for the ability, first described by 19th-century anatomist Julius Wolff, of living tissues to sense mechanical stress and respond by tissue remodeling. More recently, the scope of mechanotransduction has been expanded to include the sensation of stress, its translation into a biochemical signal, and the sequence of biological responses it produces. This book looks at mechanotransduction in a more restricted sense, focusing on the process of stress sensing and transducing a mechanical force into a cascade of biochemical signals. This stress has become increasingly recognized as one of the primary and essential factors controlling biological functions, ultimately affecting the function of the cells, tissues, and organs. A primary goal of this broad book is also to help define the new field of mechanomics, which attempts to describe the complete mechanical state of a biological system.
Download or read book Cell Biology by the Numbers written by Ron Milo and published by Garland Science. This book was released on 2015-12-07 with total page 400 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid
Download or read book Mechanics of the Cell written by David H. Boal and published by Cambridge University Press. This book was released on 2002 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: A biological physics text for a multidisciplinary audience, exploring the architectural structure of the cell.
Download or read book Mechanical Engineering of the Cytoskeleton in Developmental Biology written by and published by Academic Press. This book was released on 1994-04-22 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developing organisms are systems in which the geometry, dynamics, and boundary conditions are all changing in the course of morphogenesis. The morphogenesis of cells and organisms appear to be mediated in part by the mechanically active components of the cytoskeleton. Mechanical forces have long been considered secondary to the effects of molecular mechanisms in cell growth, differentiation, and development. This volume explores the role of mechanical forces in cell growth and development and demonstrates its importance. This volume will prove invaluable to all biologists interested in the fundamentals of mechanical forces in development, from the advanced to the graduate researcher.
Download or read book Biomechanics of Active Movement and Division of Cells written by Nuri Akkas and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: The NATO Advanced Study Institute on Biomechanics of Active Movement and Division of Cells was held September 19-29, 1993 in Istanbul and the Proceedings are presented in this volume. Sixty-eight scientists from sixteen countries attended. Prof. J. Bereiter-Hahn of Goethe-Universitat, Frankfurt, Germany, Prof. A.K. Harris of the University of North Carolina, Chapel Hill, USA, Prof. R.M. Nerem of Georgia Institute of Technology, Atlanta, USA and Prof. R. Skalak of the University of California, San Diego, USA were the members of the International Organizing Committee. As the Scientific Director of the Institute, I wish to express my sincere appreciation for their assistance without which the Institute could not have taken place. This Institute is the third one of the meetings which are now called "the NATO Istanbul Meetings on Cytomechanics". The first one was the NATO Advanced Research Workshop on Biomechanics of Cell Division which was held October 12-17, 1986 in Istanbul. The Proceedings were published as NATO ASI Series A Life Sciences Vol. 132 by Plenum Press in 1987. The second one was the NATO Advanced Study Institute on Biomechanics of Active Movement and Deformation of Cells which was held September 3-13, 1989 in Istanbul. The Proceedings were published as NATO ASI Series H : Cell Biology Vol. 42 by Springer-Verlag in 1990.
Download or read book Animal Cell Technology written by R. E. Spier and published by Elsevier. This book was released on 2013-10-22 with total page 853 pages. Available in PDF, EPUB and Kindle. Book excerpt: Animal Cell Technology: Products of Today, Prospects for Tomorrow is a collection of papers that discusses the advancement and future of biotechnology. The book presents a total of 164 materials that are organized into 22 sections. The coverage of the text includes the various methodologies involved in animal cell technology, such as post translational modifications; kinetics and modeling; and measurement and assay. The book also covers product safety and consistency testing; products from animal cells in culture; and apoptosis and cell biology. The text will be of great use to biologists, biotechnicians, and biological engineers. Readers who have an interest in the advancement of biotechnology will also benefit from the book.
Download or read book Molecular Cellular and Clinical Aspects of Angiogenesis written by Michael E. Maragoudakis and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been an explosion of research activity related to angiogenesis in recent years, and hundreds of laboratories worldwide are actively involved in many aspects of angiogenesiS. The literature on angiogenesis increases exponentially every year, and more than 16,000 peer-reviewed articles have been published the past 25 years, which are scattered in basic science and clinical journals. The complexity of the cascade of events leading to new vessel formation from preexisting ones has challenged scientists in cell biology, biochemistry, physiology, pharmacology, molecular biology, developmental biology, and other fields. With their multidisciplinary approach and the powerful new techniques that have been developed, the progress in understanding angiogenesis has been impressive indeed. Only 12 years ago the mention of an angiogenic factor caused skepticism. Today we have the complete amino-acid fiequence and their genes cloned for at least 9 angiogenic factors. Many laboratories are studying their role in angiogenesis, and several biotechnology firms have a keen interest in commercial developments relative to these molecules. The role of extracellular matrix components in angiogenesis and the interaction of endothelial cells with other cell types such as pericytes, smooth muscle cells, and inflammatory cells have been studied by other groups. This rapid expansion is the result of a realization that in many disease states a common underlying pathology is a derangement in angiogenesis.
Download or read book Tissue Engineering written by Bernhard Palsson and published by CRC Press. This book was released on 2003-03-26 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: A volume in the new Principles and Applications in Engineering series, Tissue Engineering provides an overview of the major physiologic systems of current interest to biomedical engineers: cardiovascular, endocrine, nervous, visual, auditory, gastrointestinal, and respiratory. It contains useful definitions, tables of basic physiologic data, and an introduction to the literature. Then, the book reviews the status of tissue engineering of specific organs, including bone marrow, skeletal muscle, and cartilage. Readers will acquire a good understanding of the engineering and cell biological fundamentals of tissue engineering and will develop ideas for further development of this emerging and important field.
Download or read book World Congress on Medical Physics and Biomedical Engineering May 26 31 2012 Beijing China written by Mian Long and published by Springer Science & Business Media. This book was released on 2013-02-11 with total page 2385 pages. Available in PDF, EPUB and Kindle. Book excerpt: The congress’s unique structure represents the two dimensions of technology and medicine: 13 themes on science and medical technologies intersect with five challenging main topics of medicine to create a maximum of synergy and integration of aspects on research, development and application. Each of the congress themes was chaired by two leading experts. The themes address specific topics of medicine and technology that provide multiple and excellent opportunities for exchanges.
Download or read book Biomedical Engineering Handbook 2 written by Joseph D. Bronzino and published by Springer Science & Business Media. This book was released on 2000-02-15 with total page 1528 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Tissue Engineering written by BELL and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Mechanics of the Cell written by David Boal and published by Cambridge University Press. This book was released on 2012-01-19 with total page 623 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exploring the mechanical features of biological cells, including their architecture and stability, this textbook is a pedagogical introduction to the interdisciplinary fields of cell mechanics and soft matter physics from both experimental and theoretical perspectives. This second edition has been greatly updated and expanded, with new chapters on complex filaments, the cell division cycle, the mechanisms of control and organization in the cell, and fluctuation phenomena. The textbook is now in full color which enhances the diagrams and allows the inclusion of new microscopy images. With around 280 end-of-chapter exercises exploring further applications, this textbook is ideal for advanced undergraduate and graduate students in physics and biomedical engineering. A website hosted by the author contains extra support material, diagrams and lecture notes, and is available at www.cambridge.org/Boal.
Download or read book Principles of Tissue Engineering written by Robert Lanza and published by Elsevier. This book was released on 2000-05-16 with total page 1039 pages. Available in PDF, EPUB and Kindle. Book excerpt: The opportunity that tissue engineering provides for medicine is extraordinary. In the United States alone, over half-a-trillion dollars are spent each year to care for patients who suffer from tissue loss or dysfunction. Although numerous books and reviews have been written on tissue engineering, none has been as comprehensive in its defining of the field. Principles of Tissue Engineering combines in one volume the prerequisites for a general understanding of tissue growth and development, the tools and theoretical information needed to design tissues and organs, as well as a presentation of applications of tissue engineering to diseases affecting specific organ systems. The first edition of the book, published in 1997, is the definite reference in the field. Since that time, however, the discipline has grown tremendously, and few experts would have been able to predict the explosion in our knowledge of gene expression, cell growth and differentiation, the variety of stem cells, new polymers and materials that are now available, or even the successful introduction of the first tissue-engineered products into the marketplace. There was a need for a new edition, and this need has been met with a product that defines and captures the sense of excitement, understanding and anticipation that has followed from the evolution of this fascinating and important field. Key Features* Provides vast, detailed analysis of research on all of the major systems of the human body, e.g., skin, muscle, cardiovascular, hematopoietic, and nerves* Essential to anyone working in the field* Educates and directs both the novice and advanced researcher* Provides vast, detailed analysis of research with all of the major systems of the human body, e.g. skin, muscle, cardiovascular, hematopoietic, and nerves* Has new chapters written by leaders in the latest areas of research, such as fetal tissue engineering and the universal cell* Considered the definitive reference in the field* List of contributors reads like a "who's who" of tissue engineering, and includes Robert Langer, Joseph Vacanti, Charles Vacanti, Robert Nerem, A. Hari Reddi, Gail Naughton, George Whitesides, Doug Lauffenburger, and Eugene Bell, among others
Download or read book Fetal and Neonatal Physiology written by Richard A. Polin and published by Elsevier Health Sciences. This book was released on 2011-01-01 with total page 2213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fetal and Neonatal Physiology, edited by Drs. Polin, Fox, and Abman, focuses on physiologic developments of the fetus and newborn and their impact on the clinical practice of neonatology. A must for practice, this 4th edition brings you the latest information on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. You'll also have easy access to the complete contents and illustrations online at expertconsult.com. Gain a comprehensive, state-of-the-art understanding of normal and abnormal physiology, and its relationship to disease in the fetus and newborn premature infant, from Dr. Richard Polin and other acknowledged worldwide leaders in the field. Understand the implications of fetal and neonatal physiology through chapters devoted to clinical correlation. Apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Effectively manage the consequences of intrauterine infections with three new chapters covering intrauterine infection and preterm birth, intrauterine infection and brain injury, and intrauterine infection and chronic lung disease. Access the complete contents and illustrations online at expertconsult.com - fully searchable! Get the latest developments and a full understanding of the distinct physiology of the fetus and newborn so you can treat and manage sick newborns and preemies.
