Download or read book A Practical Guide to Designing Phase II Trials in Oncology written by Sarah R. Brown and published by John Wiley & Sons. This book was released on 2014-03-28 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: How to identify optimal phase II trial designs Providing a practical guide containing the information needed to make crucial decisions regarding phase II trial designs, A Practical Guide to Designing Phase II Trials in Oncology sets forth specific points for consideration between the statistician and clinician when designing a phase II trial, including issues such as how the treatment works, choice of outcome measure and randomization, and considering both academic and industry perspectives. A comprehensive and systematic library of available phase II trial designs is included, saving time otherwise spent considering multiple manuscripts, and real-life practical examples of using this approach to design phase II trials in cancer are given. A Practical Guide to Designing Phase II Trials in Oncology: Offers a structured and practical approach to phase II trial design Considers trial design from both an academic and industry perspective Includes a structured library of available phase II trial designs Is relevant to both clinical and statistical researchers at all levels Includes real life examples of applying this approach For those new to trial design, A Practical Guide to Designing Phase II Trials in Oncology will be a unique and practical learning tool, providing an introduction to the concepts behind informed decision making in phase II trials. For more experienced practitioners, the book will offer an overview of new, less familiar approaches to phase II trial design, providing alternative options to those which they may have previously used.
Download or read book Plan 2008 written by University of Wisconsin--La Crosse and published by . This book was released on 2004 with total page 28 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Handbook of Vegetables and Vegetable Processing written by Muhammad Siddiq and published by John Wiley & Sons. This book was released on 2018-02-14 with total page 1102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Vegetables and Vegetable Processing, Second Edition is the most comprehensive guide on vegetable technology for processors, producers, and users of vegetables in food manufacturing.This complete handbook contains 42 chapters across two volumes, contributed by field experts from across the world. It provides contemporary information that brings together current knowledge and practices in the value-chain of vegetables from production through consumption. The book is unique in the sense that it includes coverage of production and postharvest technologies, innovative processing technologies, packaging, and quality management. Handbook of Vegetables and Vegetable Processing, Second Edition covers recent developments in the areas of vegetable breeding and production, postharvest physiology and storage, packaging and shelf life extension, and traditional and novel processing technologies (high-pressure processing, pulse-electric field, membrane separation, and ohmic heating). It also offers in-depth coverage of processing, packaging, and the nutritional quality of vegetables as well as information on a broader spectrum of vegetable production and processing science and technology. Coverage includes biology and classification, physiology, biochemistry, flavor and sensory properties, microbial safety and HACCP principles, nutrient and bioactive properties In-depth descriptions of key processes including, minimal processing, freezing, pasteurization and aseptic processing, fermentation, drying, packaging, and application of new technologies Entire chapters devoted to important aspects of over 20 major commercial vegetables including avocado, table olives, and textured vegetable proteins This important book will appeal to anyone studying or involved in food technology, food science, food packaging, applied nutrition, biosystems and agricultural engineering, biotechnology, horticulture, food biochemistry, plant biology, and postharvest physiology.
Download or read book Fundamentals of Cancer Detection Treatment and Prevention written by Surya K. De and published by John Wiley & Sons. This book was released on 2022-05-17 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Cancer Detection, Treatment, and Prevention The professional guide to cancer diagnosis and therapy for researchers and clinicians In Fundamentals of Cancer Detection, Treatment, and Prevention, distinguished researcher Surya K. De delivers a concise and authoritative guide to cancer treatment, diagnosis, and prevention. The book offers a comprehensive overview of cancer in humans, from its causes, symptoms, and diagnosis to the variety of treatment options available today. Intuitively organized by cancer type, this guide provides concise information on risk factors, diagnosis, and treatment options for all commonly encountered tumors, including surgery, radiation therapy, chemotherapy, and immunotherapy. All US FDA-approved drugs—like small molecules, peptides, monoclonal antibodies, whole antibodies, gene therapy, antibody-drug conjugates, and cell therapies—are considered, and information about their generic and brand names, clinical uses, and mechanisms of action is presented. Readers will also find: A thorough overview of human cancers, including cancer risk factors and possible preventions Comprehensive explorations of bladder, blood, brain, and spinal cord cancers Practical discussions of breast, colorectal, cervical, kidney, and liver cancer In-depth examinations of lung, skin, ovarian, vaginal, vulvar, pancreatic, and prostate cancers, as well as mesothelioma Perfect for pharmaceutical chemists, oncologists, pharmacologists, and medicinal chemists, Fundamentals of Cancer Detection, Treatment, and Prevention is an indispensable guide for professional researchers, whether they are working in the clinic or the pharmaceutical industry.
Download or read book Power and Gas Asset Management written by Miguel Moreira da Silva and published by Springer Nature. This book was released on 2020-01-01 with total page 165 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers meaningful insights into an impending challenge for the energy industry, namely the increasing role of asset management amongst the utilities’ core operations. In the aftermath of energy digitalization, power and gas companies will be able to seize asset productivity—through risk-based operation and maintenance—and better balance capital and operational expenditures. By addressing the asset management of both power and gas infrastructures, and by adopting a comprehensive approach—including regulation and business models, as well as a solid technology background—this book offers a unique perspective on the energy utilities’ transformation journey and the road to optimal decision-making for both asset portfolio expansion and replacement. The asset management end-to-end mission requires appropriate internal governance—depending on the business framework—and the development of decision aid models (for asset replacement and maintenance), supported on probabilistic risk and reliability indexes. This book advocates systematically digitalizing the power and gas assets, addressing both data governance and infrastructure, alongside real-time equipment condition monitoring. It also provides a meaningful methodology for designing data-centric asset management and predictive operation and maintenance, using artificial intelligence and engineering-based approaches. As such, it provides valuable strategy, methods and models—illustrated by case studies and proofs of concept—for a wide range of stakeholders, including utilities and industry professionals, regulators, policy-makers, researchers and students.
Download or read book Strategic Responses to the Eu Emission Trading Scheme written by Simon Hecker and published by GRIN Verlag. This book was released on 2011-10 with total page 149 pages. Available in PDF, EPUB and Kindle. Book excerpt: Master's Thesis from the year 2011 in the subject Economy - Environment economics, grade: 1.1, course: International Business, language: English, abstract: Emitting half of the greenhouse gases in industrialised countries, the oil and gas sector plays a central role in global GHG emissions. Environmental regulations such as the EU ETS emerged to fight climate change by reducing GHG emissions. Although those regulations increasingly affect oil and gas companies, specific implications of the EU ETS on business strategies are widely unknown. Therefore, this dissertation explores strategic responses to the EU ETS and analyses the impact of the regulation on the oil and gas sector. A strategic response framework, derived from the literature review, provides the basis for the analysis and is consequently adapted to the research findings. Empirical case studies of BP and Shell, combine secondary data and expert interviews to identify and further outline specific responses to the EU ETS. The research findings indicate that the EU ETS significantly impacts business strategies of oil and gas firms. The resulting strategic responses are mainly influenced by regulatory pressure, economic factors and competitive implications. Responses in various corporate, managerial and operational areas could be identified. From a corporate perspective, oil and gas companies support the EU ETS, as a trading scheme for carbon is preferred to other options, such as carbon taxes. Managerial responses comprise the introduction of environmental risk management systems, incorporating a carbon price into investment decisions, and the establishment of carbon trading teams, mitigating the costs of the EU ETS. Operationally, oil and gas firms responded directly by engaging in carbon trading and investing in Carbon Capture and Storage technologies. While, process improvements and lower emission generating products such as natural gases and biofuels are responses triggered by the EU ETS, investments
Download or read book The Politics of the Lisbon Agenda written by Susana Borras and published by Routledge. This book was released on 2014-06-03 with total page 159 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the year 2000, in Lisbon, the European Union launched an agenda for growth, jobs, sustainability and competiveness with a ten-year target. In 2010, the agenda was re-launched with different specific objectives but with the same final goals. Why do the European Union leaders engage with these ten-year plans? What exactly do they commit to when they do so? Do they learn from the results, or is this a rhetorical exercise that complex organizations need to raise attention to certain issues? This volume is the first-ever systematic study of the Lisbon agenda of the European Union, now called Europe 2020. It explains the rise of the Lisbon agenda as governance architectures and examines its components across time and sectors. This book was published as a special issue of the Journal of European Public Policy.
Download or read book Melanoma written by William H. Sharfman, MD and published by Demos Medical Publishing. This book was released on 2012-12-17 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging Cancer Therapeutics is a trinary hard cover periodical that is designed to provide an up-to-date evidence-based review of a dedicated emerging cancer therapy topic of interest to clinicians and scientists involved in the care of patients receiving cancer treatment. It will serve as both a reference and instructional tool for students, housestaff, fellows, practicing clinical oncologists, radiation oncologists, surgical oncologists, cancer biologists, and interdisciplinary colleagues throughout the oncology spectrum. With contributions from nationally recognized experts representing the fields of dermatology, dermatologic surgery, surgical oncology, dermatopathology, and medical oncology, Melanoma includes chapters on prevention, changes in melanoma staging, the evolving role of established surgical therapies, single-agent specific V600E mutant inhibitors, target therapy for patients without BRAF mutations, new treatments for metastatic melanoma-including ipilimumab and vemurafenib-and more.
Download or read book Williams Textbook of Endocrinology 14 Edition South Asia Edition 2 Vol Set E Book written by Shlomo Melmed and published by Elsevier India. This book was released on 2020-06-30 with total page 2250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Williams Textbook of Endocrinology, 14 Edition: South Asia Edition, 2 Vol SET - E-Book
Download or read book Multiple Myeloma written by Shaji Kumar, MD and published by Demos Medical Publishing. This book was released on 2010-08-24 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multiple Myeloma: The second issue of Emerging Cancer Therapeutics focuses on multiple myelomas also known as plasma cell myeloma, KahlerÌs Disease and myelomatosis. It is estimated that over 20,000 new cases are diagnosed each year with over 10,000 people dying from these malignancies. Multiple myelomas are highly treatable but rarely curable. Thus it is crucial for the practitioner to be up-to-date on the latest insights regarding their management. Management options and outcomes for individuals with multiple myelomas improved dramatically with the introduction of chemotherapy. Even further improvements in prognosis have occurred because of the introduction of newer therapies such as pulse corticosteroids, thalidomide, bortezomib, and autologous and allogeneic stem cell transplantation. With the increased number of therapeutic options to choose from, the clinician is better placed to offer effective therapy but at the same time is challenged to keep abreast of the rapidly changing treatment landscape and the newly emerging data that is shaping the treatment options today and in the future. Multiple Myeloma provides a comprehensive and in-depth review of this group of malignancies. This volume reviews the current literature, provides critical evaluations of the data and offers evidence-based recommendations. About the Series: Emerging Cancer Therapeutics is an invited review publication providing a through analysis of key clinical research related to cancer therapeutics, including a discussion and assessment of current evidence, current clinical best practice, and likely near future developments. There is an emphasis throughout on multidisciplinary approaches to the specialty, as well as on quality and outcomes analysis. Published three times a year Emerging Cancer Therapeutics provides authoritative, thorough assessments of advances in therapeutics in all major areas of oncology, both solid and hematologic malignancies, with a focus on advances in medical and biological therapies with emerging clinical impact and encompassing new technologies with implications for management such as molecular imaging. Features of Emerging Cancer Therapeutics include: Editorial board of nationally recognized experts across the spectrum of Cancer Therapeutics In-depth, up-to-date expert reviews and analysis of major new developments in all areas of Cancer Therapeutics Issues edited by an authority in specific subject area Focuses on major topics in Cancer Therapeutics with in-depth articles covering advances in clinical and translational research developments, as well as clinical applications and experience Emphasizes multidisciplinary approaches to research and practice
Download or read book Cap and Trade The Kyoto Protocol Greenhouse Gas GHG Emissions Carbon Tax Emission Allowances Acid Rain SO2 Program Ozone Transport Commission NOX Carbon Markets and Climate Change written by Jonathan L. Ramseur and published by The Capitol Net Inc. This book was released on with total page 567 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Lung Cancer written by Kemp H. Kernstine, MD, PhD and published by Demos Medical Publishing. This book was released on 2010-10-25 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lung Cancer: Over the course of the last decade, the treatment of lung cancer has evolved quite rapidly. New scientific and clinical advances have modified the standard of care and led to improved patient outcomes. At the same time, the treatment of lung cancer has become increasingly complex, requiring the comprehensive review and assessment of multiple issues, genetics, radiology, surgery, reconstruction, chemotherapy, and more. As a result the harmony and open communication between these specialties facilitated by a multidisciplinary team approach are crucial in providing the best care to patients and ensuring successful treatment. Lung Cancer: A Multidisciplinary Approach to Diagnosis and Management, written by a multidisciplinary team of authors representing a range of disciplines, is a valuable resource for physicians, fellows, nurses, physician assistants, physical therapists, and all health care providers involved in the treatment of lung cancer. Lung Cancer: A Multidisciplinary Approach to Diagnosis and Management summarizes the state-of-the-art issues related to the treatment of lung cancer and describes an approach for optimal multidisciplinary care for individuals who have been diagnosed with lung cancer or who are at higher risk to develop lung cancer. About the Series: The Current Multidisciplinary Oncology series edited by Charles R. Thomas consolidates and integrates the varied aspects of multidisciplinary care for major topics in oncology, including breast, lung, prostrate, head and neck and more. The volumes in the Current Multidisciplinary Oncology series will represent all related topic areas, including oncology, radiation oncology, pain, pathology, imaging, psychological support and the primary disease. In addition, each volume includes a chapter focusing on special populations and the disease's impact / difference on them, and discussion of future directions and quality of life issues. In addition each volume has a chapter written by a private practice oncologist. All Current Multidisciplinary Oncology titles provide: Consolidation and integration of the varied aspects of multidisciplinary care for major topics in oncology Coverage of all related topic areas, including medical and surgical oncology, radiation oncology, pain, pathology, imaging, psychological support, and the primary disease A chapter focusing on special populations and the disease's impact / difference on them A chapter on community practice written by a private practice oncologist Discussion of quality-of-life issues
Download or read book Natomas Levee Improvement Program Phase 4a Landslide Improvements Project Sutter and Sacramento Counties written by and published by . This book was released on 2010 with total page 734 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Meeting the energy challenge written by Great Britain: Department of Trade and Industry and published by The Stationery Office. This book was released on 2007-05-23 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are two main energy challenges: tackling climate change by reducing carbon dioxide emissions; and ensuring clean and affordable energy as the country becomes increasingly dependent on imported fuel. These challenges have to be met against the backdrop of rising fossil fuel prices; slower than anticipated liberalisation of the EU energy markets; heightened awareness of the risk arising from remaining oil and gas reserves being concentrated in a few geographical regions; and a need for substantial new investment in power stations, the electricity grid and gas infrastructure. This White Paper sets out the Governments international and domestic strategy to address these challenges and ways to implement the Energy Review of 2006 and the 2006 Pre-Budget Report. There is a separate consultation document on nuclear power.
Download or read book Lung Cancer Therapy Annual 7 written by Rolf A. Stahel and published by CRC Press. This book was released on 2012-08-13 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oncology research and practice in lung cancer continues to develop rapidly. This latest edition of Lung Cancer Therapy Annual briefs the oncology community with a review of the recent literature, emphasizing the therapeutic aspects. It offers an update of the impact that this information will have on the day-to-day management of the lung cancer pat
Download or read book Viruses and Human Cancer written by Mei Hwei Chang and published by Springer Science & Business Media. This book was released on 2013-09-06 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Research on oncogenic viruses and related human cancers has advanced rapidly in the past decade. Most articles, however, focus on a specific oncogenic virus and cancer. There is consequently a need for a comprehensive, up-to-date monograph that offers broad and integrated knowledge. Viruses and Human Cancer – From Basic Science to Clinical Prevention is designed to meet this need by providing an advanced overview on the basic and clinical aspects of oncogenic viruses and the human cancers that they cause. Virology, virus-induced inflammation and tissue injuries, oncogenic mechanisms, epidemiology, and current and emerging preventive and therapeutic strategies are all discussed in detail. In addition, the book covers the individual aspects of seven oncogenic viruses, i.e., hepatitis B virus, hepatitis C virus, human papilloma virus, Epstein-Barr virus, human T-cell lymphotropic virus, Kaposi sarcoma-associated herpes virus, and Merkel cell polyomavirus, and the related human cancers.
Download or read book Natomas Levee Improvement Program Phase 3 Landside Improvements Project written by and published by . This book was released on 2009 with total page 826 pages. Available in PDF, EPUB and Kindle. Book excerpt:
