Download or read book Final Report on Phase II Study of Academic Library Consortia written by System Development Corporation, Santa Monica, Calif and published by . This book was released on 1971 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Phase II Final Report NATO CCMS Pilot Study written by and published by DIANE Publishing. This book was released on 1998 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Technical Reports of the National Highway Traffic Safety Administration written by United States. National Highway Traffic Safety Administration. Office of Administrative Services and published by . This book was released on 1973 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Expert Scientific Group on Phase One Clinical Trials written by Expert Scientific Group on Phase One Clinical Trials and published by TSO. This book was released on 2006 with total page 700 pages. Available in PDF, EPUB and Kindle. Book excerpt: This particular Expert Scientific Group was established following the very serious adverse reactions that occurred in the first-in-man clinical trial (that is the first time the drug is given to a human) of TGN1412 in March 2006. The trial was performed in a private clinic research unit at Northwick Park Hospital in London. TGN1412 is a monoclonal antibody that was being developed as a medicine to treat leukaemia and autoimmune diseases such as rheumatoid arthritis. In the clinical trial, six healthy male volunteers experienced severe systemic adverse reactions soon after receiving TGN1412 intravenously. All six volunteers developed a cytokine (small protein molecules that transmit signals between immune cells and tissue cells) release syndrome with multi-organ failure and required intensive treatment and supportive measures. The Expert Group states that the pre-clinical development studies that were performed with TGN1412 did not predict a safe dose for use in humans, even though current regulatory requirements were met. The Expert Scientific Group has set out 22 recommendations that should increase the safety of volunteers in future clinical trials, and these cover the following areas: the preclinical and early clinical development; the process of preparation and review of clinical trial applications, and early access to advice for both regulators and sponsors; the determining and administering of the initial doses in man; the clinical environment for first-in-man studies and the development of the skills and training to meet future needs.
Download or read book Energy Research Abstracts written by and published by . This book was released on 1993 with total page 906 pages. Available in PDF, EPUB and Kindle. Book excerpt: Semiannual, with semiannual and annual indexes. References to all scientific and technical literature coming from DOE, its laboratories, energy centers, and contractors. Includes all works deriving from DOE, other related government-sponsored information, and foreign nonnuclear information. Arranged under 39 categories, e.g., Biomedical sciences, basic studies; Biomedical sciences, applied studies; Health and safety; and Fusion energy. Entry gives bibliographical information and abstract. Corporate, author, subject, report number indexes.
Download or read book Nuclear Science Abstracts written by and published by . This book was released on 1973 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: NSA is a comprehensive collection of international nuclear science and technology literature for the period 1948 through 1976, pre-dating the prestigious INIS database, which began in 1970. NSA existed as a printed product (Volumes 1-33) initially, created by DOE's predecessor, the U.S. Atomic Energy Commission (AEC). NSA includes citations to scientific and technical reports from the AEC, the U.S. Energy Research and Development Administration and its contractors, plus other agencies and international organizations, universities, and industrial and research organizations. References to books, conference proceedings, papers, patents, dissertations, engineering drawings, and journal articles from worldwide sources are also included. Abstracts and full text are provided if available.
Download or read book Research in Education written by and published by . This book was released on 1974 with total page 1262 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Scientific and Technical Aerospace Reports written by and published by . This book was released on 1990 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Technical Abstract Bulletin written by and published by . This book was released on with total page 850 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Monthly Catalogue United States Public Documents written by and published by . This book was released on 1991 with total page 1702 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Government wide Index to Federal Research Development Reports written by and published by . This book was released on 1965 with total page 1654 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Treasury and General Government Appropriations for Fiscal Year 2000 written by United States. Congress. Senate. Committee on Appropriations. Subcommittee on Treasury and General Government and published by . This book was released on 2000 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Prospective Evaluation of Applied Energy Research and Development at DOE Phase One written by National Research Council and published by National Academies Press. This book was released on 2005-07-27 with total page 138 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 2001, the National Research Council (NRC) completed a congressionally mandated assessment of the benefits and costs of DOE's fossil energy and energy efficiency R&D programs, Energy Research at DOE: Was It Worth It? The Congress followed this retrospective study by directing DOE to request the NRC to develop a methodology for assessing prospective benefits. The first phase of this projectâ€"development of the methodologyâ€"began in December 2003. Phase two will make the methodology more robust and explore related issues, and subsequent phases will apply the methodology to review the prospective benefits of different DOE fossil energy and energy efficiency R&D programs. In developing this project, three considerations were particularly important. First, the study should adapt the work of the retrospective study. Second, the project should develop a methodology that provides a rigorous calculation of benefits and risks, and a practical and consistent process for its application. Third, the methodology should be transparent, should not require extensive resources for implementation, and should produce easily understood results. This report presents the results of phase one. It focuses on adaptation of the retrospective methodology to a prospective context.
Download or read book Drug courts better DOJ data collection and evaluation efforts needed to measure impact of drug court programs written by and published by DIANE Publishing. This book was released on 2002 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report responds to your request that we assess the Department of Justices (DOJ) efforts to collect data on the performance and impact of federally funded drug court programs. The main purpose of a drug court program is to use the authority of the court to reduce crime by changing defendants substance abuse behavior. Under this concept, in exchange for the possibility of dismissed charges or reduced sentences, defendants are diverted to drug court programs in various ways and at various stages in the judicial process. Judges generally preside over drug court proceedings; monitor the progress of defendants; and prescribe sanctions and rewards as appropriate in collaboration with prosecutors, defense attorneys, treatment providers, and others. While some basic requirements are set at the federal level, most decisions about how a drug court operates are left to local jurisdictions.
Download or read book Highway Safety Literature written by and published by . This book was released on 1980 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Sharing Clinical Trial Data written by Institute of Medicine and published by National Academies Press. This book was released on 2015-04-20 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Data sharing can accelerate new discoveries by avoiding duplicative trials, stimulating new ideas for research, and enabling the maximal scientific knowledge and benefits to be gained from the efforts of clinical trial participants and investigators. At the same time, sharing clinical trial data presents risks, burdens, and challenges. These include the need to protect the privacy and honor the consent of clinical trial participants; safeguard the legitimate economic interests of sponsors; and guard against invalid secondary analyses, which could undermine trust in clinical trials or otherwise harm public health. Sharing Clinical Trial Data presents activities and strategies for the responsible sharing of clinical trial data. With the goal of increasing scientific knowledge to lead to better therapies for patients, this book identifies guiding principles and makes recommendations to maximize the benefits and minimize risks. This report offers guidance on the types of clinical trial data available at different points in the process, the points in the process at which each type of data should be shared, methods for sharing data, what groups should have access to data, and future knowledge and infrastructure needs. Responsible sharing of clinical trial data will allow other investigators to replicate published findings and carry out additional analyses, strengthen the evidence base for regulatory and clinical decisions, and increase the scientific knowledge gained from investments by the funders of clinical trials. The recommendations of Sharing Clinical Trial Data will be useful both now and well into the future as improved sharing of data leads to a stronger evidence base for treatment. This book will be of interest to stakeholders across the spectrum of research-from funders, to researchers, to journals, to physicians, and ultimately, to patients.
Download or read book Phase One Final Report written by Raymond W. Lawton and published by . This book was released on 1979 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt:
