Download or read book Vascular Pharmacology written by and published by Academic Press. This book was released on 2017-02-14 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular Pharmacology: Smooth Muscle provides up-to-date information on the structure, function, signaling, and development of vascular smooth muscle. Contributors include prominent scientists and highly-recognized experts with major accomplishments in the field of vascular smooth muscle research. Presents a must read reference on vascular smooth muscle physiology and pharmacology Contains up-to-date information on the structure, function, signaling, and development of vascular smooth muscle Includes contributors from prominent scientists and highly-recognized experts with major accomplishments in the field of vascular smooth muscle research
Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Download or read book Pharmacology of Vascular Smooth Muscle written by C. J. Garland and published by . This book was released on 1996 with total page 456 pages. Available in PDF, EPUB and Kindle. Book excerpt: The aim of this book is to provide pharmacologists with an understandi ng of how events at the cellular level impact on the cardiovascular sy stem as a whole. The pharmacological principles and major techniques r elating to this area are poorly covered in the literature at present, and this volume will be the first to provide an accessible introductio n to the subject.
Download or read book Pharmacology of Vascular Smooth Muscle written by C. J. Garland and published by . This book was released on 1996 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Pharmacology of Smooth Muscle written by Laszlo Szekeres and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 739 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and systematic survey of the present knowledge of the structure and physiological functions of smooth muscle and its response to endogenous substances and pharmacological agents. The latter includes findings on different organ systems containing smooth muscle - with the exception of the vascular system which, owing to the great amount of new knowledge accumulated in this area in recent years, is treated in a special chapter. In this connection the effect of antihypertensive agents and drugs affecting the coronary and cerebrovascular smooth muscle is also covered. For all those wishing to gain a deeper insight into smooth muscle pharmacology.
Download or read book The Endothelium written by Michel Félétou and published by Morgan & Claypool Publishers. This book was released on 2011 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: The endothelium, a monolayer of endothelial cells, constitutes the inner cellular lining of the blood vessels (arteries, veins and capillaries) and the lymphatic system, and therefore is in direct contact with the blood/lymph and the circulating cells. The endothelium is a major player in the control of blood fluidity, platelet aggregation and vascular tone, a major actor in the regulation of immunology, inflammation and angiogenesis, and an important metabolizing and an endocrine organ. Endothelial cells controls vascular tone, and thereby blood flow, by synthesizing and releasing relaxing and contracting factors such as nitric oxide, metabolites of arachidonic acid via the cyclooxygenases, lipoxygenases and cytochrome P450 pathways, various peptides (endothelin, urotensin, CNP, adrenomedullin, etc.), adenosine, purines, reactive oxygen species and so on. Additionally, endothelial ectoenzymes are required steps in the generation of vasoactive hormones such as angiotensin II. An endothelial dysfunction linked to an imbalance in the synthesis and/or the release of these various endothelial factors may explain the initiation of cardiovascular pathologies (from hypertension to atherosclerosis) or their development and perpetuation. Table of Contents: Introduction / Multiple Functions of the Endothelial Cells / Calcium Signaling in Vascular Cells and Cell-to-Cell Communications / Endothelium-Dependent Regulation of Vascular Tone / Conclusion / References
Download or read book The Vascular Smooth Muscle Cell written by and published by Elsevier. This book was released on 1995-10-24 with total page 427 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the last several years, the development of reagents that recognize smooth muscle-specific proteins has enabled researchers to identify smooth muscle cells (SMC) in tissue undergoing both differentiation and repair. These developments have led to increased research on SMC. The latest volume in the Biology of the Extracellular Matrix Series takes a current and all-encompassing look at this growing area of research. Devoted entirely to the subject of SMC, the book covers a diversity of topics-from SMC architecture and contractility to differentiation and gene expression in development. It also examines the proliferation and replication of SMC and its role in pharmacology and vascular disease. A must for cell, developmental, and molecular biologists, this book also will appeal to cardiologists, pathologists, and biomedical researchers interested in smooth muscle cells. Presents a molecular, genetic, and developmental perspective of the vas smooth muscle cell Overview sections highlight key points of chapters, including the clinical relevance of the research and expectations for future study Appeals to both the basic biologist and to the biomedical researcher of vascular disease
Download or read book Pharmacologie Et Physiologie Des Muscles Lisses written by Institut national de la santé et de la recherche médicale (France) and published by . This book was released on 1976 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Studies on the biology and pharmacology of the human vascular smooth muscle cell in culture written by Euan Nicholas Munro and published by . This book was released on 1994 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Vascular Smooth Muscle written by Maurice F. Crass and published by . This book was released on 1982 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vascular Smooth Muscle: Metabolic, Ionic, and Contractile Mechanisms addresses the vascular smooth muscle function by describing plasma lipoprotein structure, synthesis, and transport in relation to the concepts of altered vascular smooth muscle lipid metabolism leading to the genesis of atherosclerotic disease. This book is organized into six chapters and begins with an introduction to the complexities of energy metabolism and how metabolic events can be correlated with a simultaneous quantitative assessment of smooth muscle mechanics and the contractile machinery at the molecular level. The ...
Download or read book Pharmacology of Smooth Muscle written by Laszlo Szekeres and published by Springer. This book was released on 2011-12-22 with total page 727 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and systematic survey of the present knowledge of the structure and physiological functions of smooth muscle and its response to endogenous substances and pharmacological agents. The latter includes findings on different organ systems containing smooth muscle - with the exception of the vascular system which, owing to the great amount of new knowledge accumulated in this area in recent years, is treated in a special chapter. In this connection the effect of antihypertensive agents and drugs affecting the coronary and cerebrovascular smooth muscle is also covered. For all those wishing to gain a deeper insight into smooth muscle pharmacology.
Download or read book Pharmacology of Smooth Muscle written by Laszlo Szekeres and published by Springer. This book was released on 1994-11-04 with total page 727 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and systematic survey of the present knowledge of the structure and physiological functions of smooth muscle and its response to endogenous substances and pharmacological agents. The latter includes findings on different organ systems containing smooth muscle - with the exception of the vascular system which, owing to the great amount of new knowledge accumulated in this area in recent years, is treated in a special chapter. In this connection the effect of antihypertensive agents and drugs affecting the coronary and cerebrovascular smooth muscle is also covered. For all those wishing to gain a deeper insight into smooth muscle pharmacology.
Download or read book Pharmacological Studies on Vascular Smooth Muscle written by J. E. Mackenzie and published by . This book was released on 1976 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Vascular Smooth Muscle Function in Hypertension written by Theodora Szasz and published by Biota Publishing. This book was released on 2016-10-23 with total page 106 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hypertension is defined by an increase in systemic blood pressure above limits considered normal, currently set at 140 mmHg for systolic and 90 mmHg for diastolic pressure. Assuming central venous pressure to be near zero, mean arterial pressure is determined by the product of total peripheral resistance and cardiac output. In most cases of essential hypertension, as well as in animal models of hypertension, cardiac output and its main determinants, stroke volume and heart rate, are normal, whereas total peripheral resistance is increased. Total peripheral resistance is influenced by a number of factors described by the Poiseuille’s law, the most significant of which by far is the diameter of blood vessels of the arterial tree. Since blood vessel diameter is a reflection of both vascular structure and active regulation of vascular tone through mechanisms of vasoconstriction and vasodilatation, it is generally considered that alterations in total peripheral resistance are directly determined by alterations in vascular smooth muscle structure and/or function. Thus, complex blood pressure regulation systems, including renal, nervous, endocrine, immune, and others, in their turn influenced by genetic or environmental factors, converge upon the same molecular mechanisms that control the structure and function of vascular smooth muscle. In this work, rather than providing the exhaustive list of modifications in the blood pressure regulating systems that ultimately affect the vasculature in hypertension, we will focus on the structural and functional alterations of vascular smooth muscle per se during hypertension.
Download or read book Biochemistry of Smooth Muscle Contraction written by Michael Barany and published by Elsevier. This book was released on 1996-01-04 with total page 455 pages. Available in PDF, EPUB and Kindle. Book excerpt: This valuable resource provides a systematic account of the biochemistry of smooth muscle contraction. As a comprehensive guide to this rapidly growing area of research, it covers the structure and characteristic properties of contractile and regulatory proteins, with special emphasis on their predicted function in the live muscle. Also included in this book are intermediate filament proteins, and desmin and vimentin, whose function in smooth muscle is unknown; and several enzymes involved in the phosphorylation-dephosphorylation of contractile and other proteins.
Download or read book Biology of Vascular Smooth Muscle written by Yuansheng Gao and published by Springer Nature. This book was released on 2022-12-08 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a concise yet comprehensive review of the morphological, biochemical, electrical, mechanical, and metabolic properties of vascular smooth muscle, the regulation of vascular activities and the intracellular signaling involved. It particularly focuses on newly identified vasoactive agents, enzymes and transduction mechanisms. It also discusses the latest findings in the regulation of cerebral, coronary and pulmonary circulation as well as vascular activity under hypoxia and ageing. The second edition intends to update the contents of the first edition with the latest achievements in the regulation of vascular activities from biochemical, structural, genetic, physiological, and pharmacological aspects. In addition, two new chapters related to microRNA and extracellular vesicles have been added to reflect their newly discovered important roles in vascular activities. The contraction and dilatation activities of vasculature are of fundamental importance for maintaining circulation homeostasis and adapting to physiological changes. Over the last four decades, there have been significant advances in our understanding of the biochemical, structural, genetic, physiological, and pharmacological aspects of vascular activity regulation, and these insights into the responsiveness of blood vessels under normal and pathophysiological conditions help to provide valuable weapons in the fight vascular diseases. The book is of interest to researchers and graduate students, both in basic research and in clinic settings, in the field of vascular biology.
Download or read book Smooth Muscle Excitation written by T. B. Bolton and published by . This book was released on 1996 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compendium of the latest electrophysiological research on smooth muscles from an international collection of authors. It includes recent discoveries in calcium stores and their relationship to contraction and to electrical changes in the membrane. A major section of the book concentrates on calcium release mechanisms in the cell, their control, and the consequences of calcium release in the cell for membrane events. Smooth Muscle Excitation also covers the effects of chemicals released from adjacent cells. Key Features * State-of-the-art volume that represents a synopsis of all work currently being undertaken in this area throughout the world * Content covers both basic and clinical research * Provides a range of drug development studies * Presents contributions from many internationally recognized smooth muscle physiologists
