Download or read book Pharmacology of Retinoids in the Skin written by Uwe Reichert and published by . This book was released on 1989 with total page 308 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Retinoids in Dermatology written by Ayse Serap Karadag and published by CRC Press. This book was released on 2019-10-28 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Retinoids are valuable drugs in the dermatologic armamentarium, being employed in daily clinical practice. The text provides an in-depth update on the latest thinking on pharmacology, clinical use, side effects, and follow-up of retinoid therapy in dermatology; it also addresses topics related to retinoid use in special circumstances, such as vulnerable populations, concomitant surgery, and aesthetic procedures. CONTENTS: The background of retinoids * Mechanism of action of vitamin A * Mechanism of action of topical retinoids * Mechanism of action of isotretinoin * Mechanism of action of acitretin * Mechanism of action of bexarotene * Mechanism of action of alitretinoin * Effects of retinoids at the cellular level (differentiation, apoptosis, autophagy, cell cycle regulation, and senescence) * Effects of retinoids at the systemic level * New aspects of isotretinoin teratogenicity * Mucocutaneous side effects * Ophthalmologic side effects * Musculoskeletal side effects * Neurologic side effects * Psychiatric side effects * Gastrointestinal side effects * Endocrine and metabolic side effecs * Other systemic side effects: Cardiovascular, pulmonary, otolaryngorhinologic, genitourinary, renal, and immunologic * Retinoids in acne * Retinoids in hidradenitis suppurativa/acne inversa * Retinoids in rosacea * Retinoids in hair disorders * Retinoids in psoriasis * Retinoids in keratinization disorders * Retinoids in antiaging therapy * Retinoids in other skin diseases * Retinoids in lymphoma * Retinoids in cutaneous chemoprophylaxis * Guide to good clinical practice for vulnerable populations (infancy, childhood, fertile period, elderly) * Retinoids and concomitant surgery * Retinoids and concomitant aesthetic procedures * Laboratory and clinical follow-up * Teratogenicity and registry programs * Management of vitamin A and retinoid side effects * Future and novel unexplored indications of retinoids Published in association with the Journal of Dermatological Treatment.
Download or read book Comprehensive Dermatologic Drug Therapy written by Stephen E. Wolverton and published by Elsevier Health Sciences. This book was released on 2019-12-14 with total page 858 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed with practical usability in mind, Comprehensive Dermatologic Drug Therapy, 4th Edition, helps you safely and effectively treat the skin disorders you’re likely to see in your practice. Dr. Stephen E. Wolverton and new associate editor Dr. Jashin J. Wu lead a team of global experts to bring you concise, complete guidance on today's full spectrum of topical, intralesional, and systemic drugs. You’ll prescribe with confidence thanks to expert coverage of which drugs to use, when to use them, and adverse effects to monitor. Includes new drug interaction tables, drug risk profiles, and FDA guidelines, as well as two new appendices that summarize chapter questions and summarize highest-risk drug interactions. Covers the best uses for new biologic therapeutics. Contains new chapters covering medical decision-making principles, PDE-4 and JAK inhibitors, interleukin 17 inhibitors, interleukin 23 inhibitors, additional biologic therapeutics, and hedgehog pathway inhibitors. Contains quick-access summaries of indications/contraindications, dosage guidelines, drug interactions, drug monitoring guidelines, adverse effects, and treatment protocols. Features a highly detailed, disease-specific index, as well as purchase information for major drugs. Helps you assess your knowledge and prepare for certification or recertification with about 800 review questions and answers throughout the book.
Download or read book Vitamin A and Retinoids An Update of Biological Aspects and Clinical Applications written by Maria A. Livrea and published by Birkhäuser. This book was released on 2012-12-06 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid progress has been made in our understanding of the molecular mechanisms of cell growth and oncogenesis during the past decade. Special attention has been given to the presentation of the frequently neglected close correlation between changes in signal transduction and metabolic pathways during oncogenesis. This book advances the knowledge of mechanisms regulating metabolism and functioning of vitamin A and offers the most recent results of research on the clinical efficiency of retinoids in skin disorders and cancer. The book presents recent findings on the regulation of cell growth in normal and neoplastic tissues by growth factors including hormones, and by the activation and inactivation of oncogenes and tumor suppressor genes, respectively. It also offers a survey of the molecular and cell biochemistry of retinoids. Basic researchers in biochemistry, pharmacology and cell biology as well as clinicians will find this book very informative and up-to-date. This book advances the knowledge of mechanisms regulating metabolism and functioning of vitamin A and offers the most recent results of research on clinical efficiency of retinoids in skin disorders and cancer. Basic researchers in biochemistry, pharmacology, cell biology, and clinicians will find this book very informative and up-to-date. The chapters, organized in six sections, are contributed by leading scientists who have been working in the retinoid field for decades. Their experience and competence is aknowledged worldwide.
Download or read book Cosmetic Dermatology written by Zoe Diana Draelos and published by John Wiley & Sons. This book was released on 2015-10-08 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Back for a new edition, Zoe Draelos' outstanding resource to cosmetic dermatology again provides a highly-illustrated, clinical guide to the full range of cosmetic skin treatments. Bringing together experts from research, industry, surgery and practice, it is structured in four distinct parts for easy navigation by the busy clinician: Basic Concepts - giving an overview of the physiology pertinent to cosmetic dermatology and the delivery systems by which treatments can take effect; Hygiene Products - evaluating cleansing and moisturising products; Adornment - looking at aesthetic techniques such as cosmetics, nail protheses and hair treatment; Antiaging - ie, injectables, resurfacing and skin contouring techniques, and the rapidly growing area of Cosmeceuticals. With over 300 high-quality images and key summary boxes throughout, this new edition incorporates the newest procedural innovations in this rapidly developing field. Perfect for all dermatologists, especially those specialising in cosmetic dermatology and whether hospital-based or in private practice, it provides the complete cosmetic regimen for your patients and will be an indispensable tool to consult over and over again.
Download or read book Pharmacology of Topical Retinoids written by Hans Schaefer and published by S. Karger AG (Switzerland). This book was released on 1994 with total page 84 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Retinoids and Carotenoids in Dermatology written by Anders Vahlquist and published by CRC Press. This book was released on 2007-06-20 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-date reference describes how retinoids and carotenoids function in the skin and how they can be utilized to prevent and treat a wide variety of skin diseases, as well as advance biomedical research in relation to cancer treatment and immunology. Providing an in-depth update on the pharmacology, pharmacodynamics, and new applications of
Download or read book The Retinoids v 2 written by BAERT ET BAERT ET AL and published by Academic Press. This book was released on 2014-06-28 with total page 463 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Retinoids: v. 2
Download or read book Retinoids written by Heinz Nau and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 631 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the future' the decade of the 1990s will likely be viewed as a Golden Age for retinoid research. There have been unprecedented research gains in the understanding of retinoid actions and physiology; since the retinoid nuclear receptors were first identified and the importance of retinoic acid in develop mental processes was first broadly recognized in the late 1980s. Between then and now, our knowledge of retinoid action has evolved from one of a near complete lack of understanding of how retinoids act within cells to one of sophisticated understanding of the molecular processes through which retinoids modulate transcription. In this volume, we have tried to provide a comprehensive update of the present understanding of retinoid actions, with an emphasis on re cent advances. The initial chapters of the volume, or Section A, focus on the physicochemical properties and metabolism of naturally occurring retinoids: - N OY provides an uncommonly encountered view of retinoid effects from the perspective of the physiochemical properties of retinoids. - V AKIANI and BUCK lend a perspective on the biological occurrence and actions of retro- and anhydro-retinoids. Section B considers both the retinoid nuclear receptors and their mechanisms of action as well as synthetic retinoids that have been used exper imentally to provide mechanistic insights into receptor actions and have potential therapeutic use for treating disease: - PIEDRAFITA and PFAHL provide a comprehensive review of retinoid nuclear receptor biochemistry and molecular biology.
Download or read book Retinoids written by Maria A Livrea and published by CRC Press. This book was released on 1993-01-18 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains papers presented at the Conference on Retinoids: New Trends in Research and Clinical Applications, held in 1991 in Palermo, Italy, describing the latest research findings on biochemistry, nutrition, molecular and cell biology and developmental biology, as well as the pharmacology and the therapeutic use of vitamin A and its congeners.;Written by leading authorities in the field from the USA, Europe and Japan, Retinoids, amongst other things: addresses retinol-supported retinoic acid (RA) synthesis and catabolism; identifies synthetic ligands with a high selective affinity for RAR-alpha, -beta and -gamma nuclear receptors, determining if they would show pharmacological properties similar to the natural parent substance all-trans RA; considers the embryonic/foetal cellular retinoid-binding proteins and evidence for their participation in normal and abnormal morphogenesis; discusses a novel arotinoid, Ro 40-8757, that exhibited improved anti-tumour efficacy and safety in pre-clinical tests; and reports the audioradiographic distribution of retinol and RA in organs of pregnant hamsters and foetuses.
Download or read book Encyclopedia of Pharmacy Practice and Clinical Pharmacy written by and published by Academic Press. This book was released on 2019-06-28 with total page 2370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Pharmacy Practice and Clinical Pharmacy, Three Volume Set covers definitions, concepts, methods, theories and applications of clinical pharmacy and pharmacy practice. It highlights why and how this field has a significant impact on healthcare. The work brings baseline knowledge, along with the latest, most cutting-edge research. In addition, new treatments, algorithms, standard treatment guidelines, and pharmacotherapies regarding diseases and disorders are also covered. The book's main focus lies on the pharmacy practice side, covering pharmacy practice research, pharmacovigilance, pharmacoeconomics, social and administrative pharmacy, public health pharmacy, pharmaceutical systems research, the future of pharmacy, and new interventional models of pharmaceutical care. By providing concise expositions on a broad range of topics, this book is an excellent resource for those seeking information beyond their specific areas of expertise. This outstanding reference is essential for anyone involved in the study of pharmacy practice. Provides a ‘one-stop’ resource for access to information written by world-leading scholars in the field Meticulously organized, with articles split into three clear sections, it is the ideal resource for students, researchers and professionals to find relevant information Contains concise and accessible chapters that are ideal as an authoritative introduction for non-specialists and readers from the undergraduate level upwards Includes multimedia options, such as hyperlinked references and further readings, cross-references and videos
Download or read book Retinoids Advances in Basic Research and Therapy written by Constantin E. Orfanos and published by Springer. This book was released on 1981 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pharmacology and toxicology of retinoids. Biological effects of retinoids. Application of oral retinoids in psoriasis. Application of oral retinoids in acne. Oral retinoid therapy of miscellaneuous disorders of skin and oral mucosa. Clinical and laboratory monitoring of oral retinoid therapy. Short clinical and experimental reports. Present status and perspectives.
Download or read book Diet and Cancer written by Maryce M. Jacobs and published by Springer Science & Business Media. This book was released on 2013-11-22 with total page 267 pages. Available in PDF, EPUB and Kindle. Book excerpt: The American Institute for Cancer Research (AICR) sponsored its third annual confer ence on nutrition and cancer. The theme was "Diet and Cancer: Markers, Prevention, and Treatment. " The conference was held October 29-30, 1992 at the Ritz Carlton Hotel in McLean, Virginia. This proceedings contains chapters from the platform presentations and abstracts from the poster presentations. Several chapters address each of four session topics: Retinoids as Differentiation Agents in Cancer Therapy, Biological Markers of Cancer Risk, Chemoprevention of Cancer by Non-Nutrients in Foods, and Nutritional Problems and Support in the Treatment of Cancer. The first three chapters discuss in detail different mechanisms by which retinoids influence differentiation and provide evidence to support their use in cancer therapy. In vivo and in vitro studies show the effects of retinoic acid (RA) on tumorigenicity and cellu lar/molecular events. A synopsis of data showing the involvement of the retinoblastoma (RB) gene in HL-60 cell differentiation induced by RA and 1,2S-dihydroxy vitamin D3 (VD) is presented. In SCID (severe combined immunodeficiency) mice injected with HL-60 3 human leukemia cells and gavaged daily with RA, the number of tumor sites and number of mice with tumors are reduced. All trans-RA induces myeloid differentiation in HL-60 cells. Similarly, VD3 induces HL-60 monocytic differentiation. In both cases an early down regulation of retinoblastoma (RB) gene expression precedes the differentiation.
Download or read book Pediatric Dermatology written by Howard B. Pride and published by Saunders. This book was released on 2008 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: This title in the 'Requisites in Dermatology' series is the perfect resource for quick reference & rapid review in pediatric dermatology. It succinctly presents all of the most essential clinical & foundational knowledge you need for certification, recertification, or practice.
Download or read book Medicinal Chemistry of Anticancer Drugs written by Carmen Avendaño and published by Elsevier. This book was released on 2015-06-11 with total page 767 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design. Presents information in a clear and concise way using a large number of figures Historical background provides insights on how the process of drug discovery in the anticancer field has evolved Extensive references to primary literature
Download or read book Cosmeceuticals written by J. Comstock and published by Karger Medical and Scientific Publishers. This book was released on 2021-01-19 with total page 178 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cosmeceuticals are ingredients or products that provide cosmetic and therapeutic benefits and which can be obtained without a prescription. They are one of the fastest growing segments in the personal care product market. Even in the worst economic climate, sales of cosmetics remain robust. Beauty enhancers are our best means of feel-good escapism, and we are not about to give them up. The ingredients, sales locations, and the regulation of sales are dynamic aspects of the industry. Here we give you a heads-up on where the market is going so you can make strategic decisions for your practice. This book will give you an understanding of facial cosmeceuticals examining the needs of the face, moisturizer formulation, noninvasive testing, and clinical evaluation to establish efficacy. It sheds light on topics such as the delivery mechanisms of active ingredients, vitamin A and C and other antioxidants, growth factors and stem cells, peptides, or amino acids. Topics also include the use of cosmeceuticals for the treatment of acne, rosacea, and hair loss and for hair care as well as the treatment of scars and cosmeceuticals for sun protection and protection from pollution. It also covers aspects of nutraceuticals and diets for healthy skin.
Download or read book Retinoid Signaling Pathways written by and published by Academic Press. This book was released on 2020-04-29 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: Retinoid Signaling Pathways, Volume 637, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Sections in this release include The chemistry and biochemistry of Vitamin A and its natural derivative, Biosynthesis of retinoic acids, Biodegration of retinoic acids mediated by retinoid binding proteins, Retinoic acid homeostasis, Cryo Electron Microscopy to study retinol update via the STRA6 receptor, Immuno-detection of retinoic acid synthesis enzymes in the brain, classical pathway of gene regulation by retinoids, Protein-protein interactions in the regulation of retinoid acid receptors activity, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series Includes the latest information on retinoid signaling pathways
