Download or read book Some Organophosphate Insecticides and Herbicides written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 2017 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the IARC Monographs provides evaluations of the carcinogenicity of some organophosphate insecticides and herbicides, including diazinon, glyphosate, malathion, parathion, and tetrachlorvinphos. Diazinon acts on a wide range of insects on crops, gardens, livestock, and pets, but most uses have been restricted in the USA, Canada, and the European Union since the 1980s. Glyphosate is the most heavily used agricultural and residential herbicide in the world, and has been detected in soil, air, surface water, and groundwater, as well as in food. Malathion is one of the oldest and most widely used organophosphate insecticides, and has a broad spectrum of applications in agriculture and public health, notably mosquito control. The insecticide parathion has been largely banned or restricted throughout the world due to toxicity to wildlife and humans. Tetrachlorvinphos is banned in the European Union, but continues to be used in the USA and elsewhere as an insecticide on animals, including in pet flea collars. The IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of these agents.

Download or read book Toxicological profile for methyl parathion written by and published by . This book was released on 2001 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: The ATSDR toxicological profile succinctly characterizes the toxicology and adverse health effects information for the toxic substance described therein. Each peer-reviewed profile identifies and reviews the key literature that describes a substance's toxicological properties. This public health statement tells you about methyl parathion and the effects of exposure.

Download or read book Advances in Parathion Research and Application 2012 Edition written by and published by ScholarlyEditions. This book was released on 2012-12-26 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Parathion Research and Application / 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Parathion in a concise format. The editors have built Advances in Parathion Research and Application / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Parathion in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Parathion Research and Application / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book Advances in Parathion Research and Application 2011 Edition written by and published by ScholarlyEditions. This book was released on 2012-01-09 with total page 22 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in Parathion Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Parathion in a compact format. The editors have built Advances in Parathion Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Parathion in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Parathion Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Download or read book Cancer Hazards Parathion Malathion Diazinon Tetrachlorvinphos and Glyphosate written by Martha Richmond and published by Springer Nature. This book was released on 2022-02-26 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on a monograph published in 2017 by the International Agency for Research on Cancer (IARC), an agency of the World Health Organization (WHO), discussing its carcinogen hazard classification of four pesticides: parathion, malathion, diazinon, and tetrachlorvinphos as well as the herbicide glyphosate. The monograph provided a detailed discussion of considerations and conclusions made by a group of experts who met in 2015 to evaluate these compounds. Although not universally true, many of these substances, from the time of their commercial introduction to their present-day use, have spread significantly in the environment, affecting animals and plants in the larger ecosystem, the overall health of the environment, and human health. This book develops each of these issues before turning to the IARC review process, both the general process and its evolution over time, and compound selection criteria and deliberations regarding the substances discussed in the 2017 monograph. Final book sections detail scientific and private sector reactions to and implications of the IARC classifications. Hazard identification is contrasted with various models of quantitative risk assessment. The last chapters highlight the importance of hazard identification for members of domestic and global underserved communities involved in farming and landscape work, where exposures may vary widely, are not well-regulated, and where health outcomes are often not carefully documented.

Download or read book Low volume and Ultralow volume Sprays of Malathion and Methyl Parathion for Control of Three Lepidopterous Cotton Pests written by Dan A. Wolfenbarger and published by . This book was released on 1971 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Low volume and Ultralow volume Sprays of Malathion and Methyl Parathion for Control of Three Lepidopterous Cotton Pests written by B. R. Burmester and published by . This book was released on 1970 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Tissue Changes in Puffers Exposed to Methoxychlor and Methyl Parathion written by Ronald Eisler and published by . This book was released on 1967 with total page 18 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adult northern puffers were exposed for periods up to 45 days to either 30 parts per billion (ppb) of the organochloride insecticide methoxychlor, 20, 200 ppb of the organophosphorous insecticide methyl parathion, or to a combination of 15 ppb of methoxychlor and 10, 100 ppb of methyl parathion. These concentrations will produce approximately 5 percent mortality in 96 hours under the conditions of the experiment. Profiles were constructed on the effects of each insecticide on blood and tissue components. The visual patterns provided by these profiles suggest a means of identifying unfavorable environmental conditions before the appearence of obvious morphological or physiological changes.

Download or read book Parathion in Aerosols for the Control of Pests on Greenhouse Ornamentals written by Floyd Franklin Smith and published by . This book was released on 1948 with total page 8 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Download or read book Toxicology of Organophosphate and Carbamate Compounds written by Ramesh C Gupta and published by Academic Press. This book was released on 2011-04-28 with total page 781 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use continues to pose a threat to human and animal health, aquatic systems and wildlife. These anticholinesterase agents produce a variety of toxicological effects in target and nontarget organs. In light of this complexicity, this multi-authored book is written by the well known scientists from many countries. The book is organized into nine sections, with a total of 49 chapters, to provide in-depth knowledge on various aspects of OP and CM compounds, including their use, classification, mechanism-based toxicity, and prophylactic and therapeutic measurements. Several chapters are written with special emphasis to cover timely topics, such as chemical warfare agents, physiologically-based pharmacokinetic modeling, structure and function of cholinesterases, paraoxonase, carboxylesterases; developmental neurotoxicity, the intermediate syndrome, oxidative stress, endocrine disruption, and DNA damage/gene expression and carcinogenesis. Section-VI with 5 chapters is specifically devoted to risk assessment, and safety and regulatory guidelines for pesticides. - Describes everything you need to know about Organophosphates and Carbamates - Extensively covers pesticides, nerve agents, therapeutic drugs, and flame retardants - Describes epidemiology of the world's major disasters involving Organophosphates and Carbamates - Covers animal, human, aquatic, and wildlife toxicity of Anticholinesterases - Insights into in-depth cholinergic and noncholinergic mechanisms of toxicity - Describes recent advancements in cholinesterases, paraoxonases, carboxylesterases, oxidative stress, endocrine disruption, cardiac and pulmonary toxicity, and carcinogenesis - Provides in vitro and in vivo models for neurotoxicity testing - Integrates knowledge of studies in lab animals and humans - Offers risk/safety assessment and national/international guidelines for permissible levels of pesticide residues - Describes management of Anticholinesterase poisoning in humans

Download or read book Circle of Poison written by David Weir and published by Food First Books. This book was released on 1981 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: Every minute, someone in the Third World becomes a victim of pesticide poisoning. Circle of Poison documents the international marketing of restricted pesticides that leave a globe-circling trail of sickness and death. But the circle's victims are not silent. Around the world, people are fighting back.

Download or read book Beilsteins Handbuch Der Organischen Chemie written by Friedrich Konrad Beilstein and published by Arkose Press. This book was released on 2015-09-27 with total page 940 pages. Available in PDF, EPUB and Kindle. Book excerpt: This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Download or read book Metabolic Pathways of Agrochemicals written by Terry R Roberts and published by Royal Society of Chemistry. This book was released on 2007-10-31 with total page 872 pages. Available in PDF, EPUB and Kindle. Book excerpt: This important publication provides a comprehensive summary of data and information on the metabolism and chemical degradation of agrochemicals in soils, plants and animals. Part 1, Herbicides and Plant Growth Regulators, and Part 2, Insecticides and Fungicides, together provide a major bibliography, as each entry is fully referenced. Contents include metabolic products, pathways and mechanisms, together with useful details on physico-chemical properties and mode of action. Both parts are organised by class of chemical for easy reference. There are separate entries for each pesticide, covering most commercially available chemicals in use today. In addition, an overview of the metabolism of each major class provides the reader with an informed summary of key similarities and significant differences between individual chemicals. Information is based primarily on literature from the past 40 years of research, together with some important, previously unpublished work provided by the agrochemical companies. Presented in a systematic, easy-to-read style, with extensive indexing to facilitate the rapid location of required information and the comparison of related compounds, Metabolic Pathways of Agrochemicals is an invaluable reference for chemists, biochemists and biologists working in the discovery, development and registration of agrochemicals, as well as scientists in related areas such as design and mode of action of pharmaceuticals.

Download or read book Tear Gas written by Anna Feigenbaum and published by Verso Books. This book was released on 2017-11-07 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: One hundred years ago, French troops fired tear gas grenades into German trenches. Designed to force people out from behind barricades and trenches, tear gas causes burning of the eyes and skin, tearing, and gagging. Chemical weapons are now banned from war zones. But today, tear gas has become the most commonly used form of "less-lethal" police force. In 2011, the year that protests exploded from the Arab Spring to Occupy Wall Street, tear gas sales tripled. Most tear gas is produced in the United States, and many images of protestors in Tahrir Square showed tear gas canisters with "Made in USA" printed on them, while Britain continues to sell tear gas to countries on its own human-rights blacklist. An engrossing century-spanning narrative, Tear Gas is the first history of this weapon, and takes us from military labs and chemical weapons expos to union assemblies and protest camps, drawing on declassified reports and witness testimonies to show how policing with poison came to be.

Download or read book Dirty War written by Glenn Cross and published by Helion and Company. This book was released on 2017-03-21 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dirty War is the first comprehensive look at the Rhodesia’s top secret use of chemical and biological weapons (CBW) during their long counterinsurgency against native African nationalists. Having declared its independence from Great Britain in 1965, the government—made up of European settlers and their descendants—almost immediately faced a growing threat from native African nationalists. In the midst of this long and terrible conflict, Rhodesia resorted to chemical and biological weapons against an elusive guerrilla adversary. A small team made up of a few scientists and their students at a remote Rhodesian fort to produce lethal agents for use. Cloaked in the strictest secrecy, these efforts were overseen by a battle-hardened and ruthless officer of Rhodesia’s Special Branch and his select team of policemen. Answerable only to the head of Rhodesian intelligence and the Prime Minister, these men working alongside Rhodesia’s elite counterguerrilla military unit, the Selous Scouts, developed the ingenious means to deploy their poisons against the insurgents. The effect of the poisons and disease agents devastated the insurgent groups both inside Rhodesia and at their base camps in neighboring countries. At times in the conflict, the Rhodesians thought that their poisons effort would bring the decisive blow against the guerrillas. For months at a time, the Rhodesian use of CBW accounted for higher casualty rates than conventional weapons. In the end, however, neither CBW use nor conventional battlefield successes could turn the tide. Lacking international political or economic support, Rhodesia’s fate from the outset was doomed. Eventually the conflict was settled by the ballot box and Rhodesia became independent Zimbabwe in April 1980. Dirty War is the culmination of nearly two decades of painstaking research and interviews of dozens of former Rhodesian officers who either participated or were knowledgeable about the top secret development and use of CBW. The book also draws on the handful of remaining classified Rhodesian documents that tell the story of the CBW program. Dirty War combines all of the available evidence to provide a compelling account of how a small group of men prepared and used CBW to devastating effect against a largely unprepared and unwitting enemy. Looking at the use of CBW in the context of the Rhodesian conflict, Dirty War provides unique insights into the motivation behind CBW development and use by states, especially by states combating internal insurgencies. As the norms against CBW use have seemingly eroded with CW use evident in Iraq and most recently in Syria, the lessons of the Rhodesian experience are all the more valid and timely.

Download or read book Toxicology of Pesticides written by Lucio G. Costa and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: The protection of human health and food and fiber resources against the ravages of pests of many sorts is a continuous struggle by all people in the world. The use of chemical pesticides as an aid in this struggle is now also global. These chemicals are deliberately added to the environment for the purpose of killing or injuring some form of life. Because pesticides are generally less selectively toxic than would be desired, non-target species, including humans, must be protected from injury by these chemicals. This can only be achieved by thorough understanding of the comparative toxicology of these compounds, and by minimizing human (and other desirable species) exposure. The latter can only be achieved by sound regulatory policies that utilize scientific principles and data, properly tempered by both gaps in that data and sociologic and economic considerations. This book contains the proceedings of the NATO Advanced Study Institute on "Toxicology of Pesticides: Experimental, Clinical and Regulatory Perspectives" held in Riva del Garda on October 6-15, 1986. This NATO-ASI has been promoted by the School of Public Health and Community Medicine, University of Washington at Seattle, by the Institute of Pharmacological Sciences, University of Milano and by the Giovanni Lorenzini Foundation, and has been sponsored by both the Society of Toxicology (USA) and the Italian Society of Toxicology.

Download or read book Paraoxonase PON1 in Health and Disease written by Lucio G. Costa and published by Springer Science & Business Media. This book was released on 2002-11-30 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: The journey to find genes responsible for determining sensitivity or resistance to specific insecticides led to the paraoxonase (PON1) gene on human chromosome 7. This gene encodes a 355 amino acid protein that is localized on the high density lipoprotein (HDL) particles in plasma. Characterization of this gene revealed that different individuals expressed both different forms of this enzyme with amino acid substitutions at positions 55 and 192 as well as different levels of this protein. Additional studies showed that mutations in the regulatory region of the PON1 gene contributed to the very different levels of plasma PON1 among individuals. It turned out that both the level of the enzyme as well as the amino acid present at position 192 (glutamine or arginine) are important in determining resistance to the active forms of specific organophosphorus insecticides, especially diazinon and chlorpyrifos. The position 192 amino acid also determined whether an individual's plasma hydrolyzed the nerve agents soman and sarin at high or low rates. It is not yet known whether these different rates of hydrolysis observed in biochemical assays reflect differences in sensitivity of individuals to nerve agents. Taken together, all of the experiments carried out to date indicate that engineered recombinant PON1 is an excellent candidate to use for treating cases of poisoning by specific organophosphorus compounds. The available data on the relationship of PON1 levels and position 192 genotype led us to introduce the term PON1 status to describe an individual's PON1 plasma level as well as their position 192 genotype.The characterization of the genetic variations of the PON1 gene together with experiments showing that HDL can protect the lipids in low density lipoprotein particles (LDL) from oxidation and that it was PON1 that was responsible for this protection have opened an entirely new area of investigation, the role of PON1 in protecting against vascular disease.More recent reports have noted that PON1 also metabolizes a number of drugs, activating some and inactivating others.This book describes the recent advances in understanding the role of PON1 in both cardiovascular disease and toxicology of insecticide exposure as well as some of the recent information indicating an important possible role in the pharmacokinetics of drug metabolism. The final chapter of the book provides an overview of the areas of PON1 research and suggests future directions for research on PON1 as well as the related, linked genes PON2 and PON3.