Download or read book Facing the Spears of Change written by Marie Alohalani Brown and published by University of Hawaii Press. This book was released on 2016-05-31 with total page 249 pages. Available in PDF, EPUB and Kindle. Book excerpt: Facing the Spears of Change takes a close look at the extraordinary life of John Papa `Ī`ī. Over the years, `Ī`ī faced many personal and political changes and challenges in rapid succession, which he skillfully parried or seized, then used to fend off other attacks. He began serving in the household of Kamehameha I as an attendant in 1810, at the age of ten, and became highly familiar with the inner workings of the royal household. His early service took place in a time when ali`i nui (the highest-ranking Hawaiians) were considered divine and surrounded with strict kapu (sacred prohibitions); breaking a kapu pertaining to an ali`i meant death for the transgressor. He went on to become an influential statesman, privy to the shifting modes of governance adopted by the Hawaiian kingdom. `Ī`ī’s intelligence and his good standing with those he served resulted in a great degree of influence within the Hawaiian government, with his fellow Hawaiians, and with the missionaries residing in the Hawaiian Islands. As a privileged spectator and key participant, his published accounts of ali`i and his insights into early nineteenth-century Hawaiian cultural-religious practices are unsurpassed. In this groundbreaking work, Marie Alohalani Brown offers an elegantly written and compelling portrait of an important historical figure in nineteenth-century Hawai`i. Brown’s extensive archival research using Hawaiian and English language primary sources from the 1800s allows access to information which would be otherwise unknown but to a very small circle of researchers.
Download or read book Papa s Game written by Gregory Wallance and published by Rawson Wade Publishers. This book was released on 1981 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Frontiers of Cellular Bioenergetics written by S. Papa and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 827 pages. Available in PDF, EPUB and Kindle. Book excerpt: 1. The Mitochondrial and Bacterial Respiratory Chains: From MacMunn and Keilin to Current Concepts; P. Nicholls. 2. The Mitochondrial Enzymes of Oxidative Phosphorylation; Y. Hatefi. 3. Proton Pumps of Respiratory Chain Enzymes; S. Papa, et al. 4. Uncoupling of Respiration and Phosphorylation; V.P. Skulachev. 5. Crystallization, Structure, and Possible Mechanism of Action of Cytochrome c Oxidase from the Soil Bacterium Paracoccus denitrificans; M. Hartmut, et al. 6. The Structure of Crystalline Bovine Heart Cytochrome c Oxidase; S. Yoshikawa, et al. 7. Electron and Proton Transfer in.
Download or read book Meissner V Papas written by and published by . This book was released on 1941 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Advances in Mitochondrial Medicine written by Roberto Scatena and published by Springer Science & Business Media. This book was released on 2012-02-09 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria are far more than the “powerhouse” of the cell as they have classically been described. In fact, mitochondria biological activities have progressively expanded to include not only various bioenergetic processes but also important biosynthetic pathways, calcium homeostasis and thermogenesis, cell death by apoptosis, several different signal transduction pathways mainly related to redox control of gene expression and so on. This functional and structural complexity may undergo important derangements so to justify the definition of ‘mitochondrial medicine’, which should include all the clinical consequences of congenital or acquired mitochondrial dysfunctions. There are actually a growing number of studies which assign a significant pathogenic role to damaged mitochondria in different diseases: ischemia/reperfusion injury, neurodegenerative diseases, cancer with its dramatic sequelae (i.e, metastasis), metabolic syndrome, hyperlipidemias, just to mention a few of the most important pathologies. In this context, a further aspect that should not be disregarded is the interaction of pharmacological agents with mitochondria, not only in regard of the toxicological aspects but, above all, of the potential therapeutic applications. In fact, it is interesting to note that, while the properties of different so-called “mitoxicants” are well-known, the subtle linkages between drugs and mitochondria is still in need of a real pharmacological and therapeutic control at the clinical level. This lack of consideration can often lead to an underestimation of unwanted toxic effects but also of desirable therapeutic activities. A reevaluation of the potential clinical role of mitochondria could give a new light on some yet obscure aspects of human pathophysiology.
Download or read book Free Radicals Oxidative Stress and Antioxidants written by Tomris Özben and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been an explosion of research related to free radicals and antioxidants in recent years, and hundreds of laboratories worldwide are actively involved in many as pects of free radicals, oxidative stress, and antioxidants. The literature on these topics in creases exponentially every year. Over the last few years, we have been fortunate to witness a widespread recognition of the important role of free radicals in a wide variety of pathological conditions including diseases such as atherosclerosis, cardiovascular and neurological diseases, ischemia, emphysema, diabetes, radiation injury, cancer, etc. In ad dition, many laboratories are studying the role of free radicals in the inexorable process of aging. Increased evidence involves free radicals with the etiology of various diseases, thereby suggesting the use of antioxidants as a viable therapeutic approach for the treat ment of free radical mediated pathologies. Despite these impressive developments, many important aspects of free radical and antioxidant research are open for investigation. It is important to understand the overall mechanisms involved in free radical mediated physiological and pathological conditions. This knowledge will undoubtedly lead to the development of new therapeutic approaches to prevent or control free radical related diseases. This book contains the proceedings of the NATO Advanced Study Institute (ASI) on "Free Radicals, Oxidative Stress, and Antioxidants: Pathological and Physiological Sig nificance," which was held in Antalya, Turkey from May 24-June 4, 1997.
Download or read book Detection of Mitochondrial Diseases written by F.N. Gellerich and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: In October 1995, the 1st Colloquium on Mitochondria and Myopathies in Halle/Saale was organized in Halle/Saale by the editors of this focused issue. The meeting took up what might be called an East German tradition: from 1976 to 1990 Andreas Schmidt organized seven clinically orientated Colloquia on Myology in Jena, and from 1974 to 1990 a series of twelve Colloquia on Mitochondria focused on basic research aspects was arranged by Wolfgang Kunz in Magdeburg. At those meetings, East Germany was a mediator between East European, West European and American scientists. In continuation of this tradition, scientists from more than 17 countries working on mitochondria as neurologists, biochemists, geneticists, or as physiologists came to Halle. The title of the colloquium indicated the combination of both basic and clinical mitochondrial research. The most important contributions of this meeting are now published in this focused issue. We thank all authors for their patience and cooperation that have made it possible to produce this unique collection of papers representing current knowledge on detection of mitochondrial causes of diseases. We especially thank Prof. N.S. Dhalla for making it possible to publish these contributions together in this focused issue and also as a hard-cover book.
Download or read book The Mamas and The Papas Songbook written by The Mamas and The Papas and published by Hal Leonard Corporation. This book was released on 1991-10-01 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: (Piano/Vocal/Guitar Artist Songbook). 16 of their greatest hits in piano/vocal/guitar notation, plus a complete history of the band. Includes: California Dreamin' * Creeque Alley * Dancing in the Street * Dedicated to the One I Love * Dream a Little Dream of Me * Glad to Be Unhappy * Go Where You Wanna Go * Got a Feelin' * I Call Your Name * I Saw Her Again * Look Through My Window * Midnight Voyage * Monday, Monday * My Girl * Words of Love * Twelve-Thirty (Young Girls Are Coming to the Canyon).
Download or read book Cell Growth and Oncogenesis written by S. Papa and published by Birkhäuser. This book was released on 2013-03-11 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid progress has been made in our understanding of the molecular mechanisms of cell growth and oncogenesis during the past decade. This book comprises recent results on the regulation of cell growth in normal and neoplastic tissues by growth factors including hormones, and by the activation and inactivation of oncogenes and tumor suppressor genes, respectively. Special attention has been given to the presentation of the frequently neglected close correlation between changes in signal transduction and metabolism pathways during oncogenesis.
Download or read book Child Language Creolization and Historical Change written by Eduardo D. Faingold and published by Gunter Narr Verlag. This book was released on 1996 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book You re Doing Great written by Tom Papa and published by St. Martin's Press. This book was released on 2020-05-12 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: Comedian and Live from Here head writer Tom Papa, author of Your Dad Stole My Rake, tackles the modern condition in a heartwarming group of short essays. Tom Papa is a little worried about you. You seem stressed, overworked and, frankly, a little mixed up. Everyone is fighting an overwhelming feeling that things are getting worse, that we should be doing more, that we’re not good enough. Well, life isn't perfect. There have always been problems and there always will be. You can fight for the things you believe in, you can work really, really hard, but you shouldn't lose track of the fact that while you’re doing all that, life is flying by at lightning-fast speed. If you actually take a breath and look around you’ll realize you’re actually doing great. Here’s the thing: We live in an amazing time filled with airplanes, scooters, and peanut butter cups. We have air conditioning, blenders, and martini shakers. It's time to refocus, enjoy it all, and stop waiting for something better! Relax with comedian and Live from Here writer and performer Tom Papa as he explores his favorite subjects in 75 essays, including: You Don't Have to Live Your Best Life Don't Open the Mail I'm So Baked I Love Your Love Handles Don't Go Tubing Shut Up and Eat Recalibrate, turn off your device, and open your eyes to a better reality: You’re doing great!
Download or read book The New Century Perfect Speaker written by John Coulter and published by . This book was released on 1901 with total page 568 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Life in the New World Or Sketches of American Society written by Charles Sealsfield and published by . This book was released on 1844 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Spy written by and published by . This book was released on 1989-01 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smart. Funny. Fearless."It's pretty safe to say that Spy was the most influential magazine of the 1980s. It might have remade New York's cultural landscape; it definitely changed the whole tone of magazine journalism. It was cruel, brilliant, beautifully written and perfectly designed, and feared by all. There's no magazine I know of that's so continually referenced, held up as a benchmark, and whose demise is so lamented" --Dave Eggers. "It's a piece of garbage" --Donald Trump.
Download or read book New Research on Atherosclerosis written by Leon V. Clark and published by Nova Publishers. This book was released on 2006 with total page 122 pages. Available in PDF, EPUB and Kindle. Book excerpt: Atherosclerosis is a degenerative condition in which arteries build up deposits called plaques (atheromas) which consist of lipids (mainly cholesterol), connective tissue and smooth muscle cells originating from the arterial wall. Plaques develop quietly over a period of years and are unnoticeable until there is an interruption in the normal flow of blood. Plaques may partially or totally block the blood's flow through an artery. Two things that can happen where plaques occur are: bleeding (haemorrhage) into the plaque; and formation of a blood clot (thrombus) on the plaque's surface. Atherosclerosis affects large and medium-sized arteries. The type of artery and where the plaque develops varies with each person. Atherosclerosis research has witnessed startling progress in recent years, partially due to new drugs as well as to new breakthroughs in molecular medicine.
Download or read book The Nanas and the Papas written by Kathryn Zullo and published by Andrews McMeel Publishing. This book was released on 1998 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt: When Kathryn and Allan Zullo learned they were going to be grandparents, they were thrilled. The next emotion the two fortysomething felt was panic. "What do we really know about being grandparents?" they tought. "We're nothing like our gray-haired grandmas and grandpas." To answer their questions--and those of a new generation of grandparents--they created The Nanas and the Papas. They went to leading experts in child care and grandparenting, including T. Berry Brazelton, Arthur Kornhaber, and Perry Buffington, all of whom generously shared their views on the issues confronting boomer grandparents. Then they talked to other boomer nanas and papas, from friends next door to Internet acquaintances across the country.
Download or read book Papas with Ponytails written by Alexandra Flowers and published by Lulu.com. This book was released on 2019-09-25 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: For author Alexandra Flowers, the mantra, "strength, wisdom, courage; strength, wisdom, courage," helps settle her mind and get through stressful times. In Papas with Ponytails, she shares how she came to this point in her life. This memoir offers an account of Alexandra Flowers' journey. It includes the recollection of a host of painful experiences which include surviving an abusive husband, the heartache of having her son stolen, being in Iran during the hostage crisis in 1980, her despair in rejecting God and turning to drugs and alcohol, and includes tales of her experiences with ghosts and prophetic dreams. Papas with Ponytails also highlights her accomplishments of overcoming fear and insecurity, working with refugees in Costa Rica, achieving recovery, working with teenagers, accomplishing lifelong dreams by earning two college degrees, as well as details of her son's dangerous attempt to escape Iran in hope of reuniting with his mother.
